|
FR2656800B1
(fr)
|
1990-01-08 |
1992-05-15 |
Roussy Inst Gustave |
Nouvelles proteines produits par les lymphocytes humains, sequence d'adn codant pour ces proteines et applications pharmaceutiques et biologiques.
|
|
US5976877A
(en)
|
1990-01-08 |
1999-11-02 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Proteins produced by human lymphocytes DNA sequence encoding these proteins and their pharmaceutical and biological uses
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
ES2281899T3
(es)
|
1994-05-06 |
2007-10-01 |
Institut Gustave Roussy |
Fracciones polipeptidicas solubles de la proteina lag-3; procedimiento de produccion; composicion terapeutica; anticuerpo anti-idiotipo.
|
|
AU701375B2
(en)
|
1995-07-21 |
1999-01-28 |
Institut Gustave Roussy |
Methods for detecting, identifying, isolating, and selectively labelling and targeting Th1 lymphocytes by means of the LAG-3 protein
|
|
US5811097A
(en)
|
1995-07-25 |
1998-09-22 |
The Regents Of The University Of California |
Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling
|
|
EP0885131B1
(en)
|
1996-03-07 |
2002-06-12 |
Isotag Technology, Inc. |
Near infrared fluorescent security thermal transfer printing and marking ribbons
|
|
US6482925B1
(en)
|
1996-11-28 |
2002-11-19 |
Applied Research Systems Ars Holding N.V. |
Mutants of the LAG-3 proteins and nucleotides encoding LAG-3 mutants
|
|
JP3920928B2
(ja)
|
1996-11-29 |
2007-05-30 |
アプライド・リサーチ・システムズ・エイアールエス・ホールディング・ナムローゼ・フェンノートシャップ |
移植片拒絶反応の防止法および普遍的遺伝子治療宿主細胞の生産法
|
|
JP2001523958A
(ja)
|
1997-03-21 |
2001-11-27 |
ブライハム アンド ウィミンズ ホスピタル,インコーポレイテッド |
免疫療法のctla−4結合ペプチド
|
|
EP0900841A1
(en)
|
1997-06-18 |
1999-03-10 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
LAG-3 splice variants
|
|
DK1141028T3
(da)
|
1998-12-23 |
2010-05-25 |
Pfizer |
Humane monoklonale antistoffer til CTLA-4
|
|
GB9911569D0
(en)
|
1999-05-18 |
1999-07-21 |
Oxford Biomedica Ltd |
Antibodies
|
|
EP1210428B1
(en)
|
1999-08-23 |
2015-03-18 |
Dana-Farber Cancer Institute, Inc. |
Pd-1, a receptor for b7-4, and uses therefor
|
|
EP1210424B1
(en)
|
1999-08-23 |
2007-02-07 |
Dana-Farber Cancer Institute, Inc. |
Novel b7-4 molecules and uses therefor
|
|
IL148079A0
(en)
|
1999-08-24 |
2002-09-12 |
Medarex Inc |
Human ctla-4 antibodies and compositions containing the same
|
|
US7605238B2
(en)
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
|
AU784634B2
(en)
|
1999-11-30 |
2006-05-18 |
Mayo Foundation For Medical Education And Research |
B7-H1, a novel immunoregulatory molecule
|
|
AU2001268427B2
(en)
|
2000-06-16 |
2007-03-29 |
Glaxosmithkline Intellectual Property Limited |
Antibodies that immunospecifically bind to blys
|
|
CN1487996B
(zh)
|
2000-11-30 |
2010-06-16 |
米德列斯公司 |
用于生产人类抗体的转基因转染色体啮齿动物
|
|
US7538206B2
(en)
|
2001-02-22 |
2009-05-26 |
Institut Pasteur |
Comparative mycobacterial geneomics as a tool for identifying targets for the diagnosis, prophylaxis or treatment of mycobacterioses
|
|
US20020146753A1
(en)
|
2001-04-06 |
2002-10-10 |
Henrik Ditzel |
Autoantibodies to glucose-6-phosphate isomerase and their participation in autoimmune disease
|
|
EP1295895B1
(en)
|
2001-09-19 |
2011-08-10 |
Institut Gustave Roussy |
Peptides and proteins binding to glu-pro motifs, therapeutical compositions containing the same and applications thereof
|
|
US7306906B2
(en)
|
2001-09-19 |
2007-12-11 |
Alexion Pharmaceuticals, Inc. |
Engineered templates and their use in single primer amplification
|
|
WO2003088808A2
(en)
|
2002-04-16 |
2003-10-30 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
EP2388265A1
(en)
|
2002-02-22 |
2011-11-23 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
IL149820A0
(en)
|
2002-05-23 |
2002-11-10 |
Curetech Ltd |
Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency
|
|
ES2350687T3
(es)
|
2002-07-03 |
2011-01-26 |
Ono Pharmaceutical Co., Ltd. |
Composiciones de inmunopotenciación.
|
|
CA2492143A1
(en)
*
|
2002-07-12 |
2004-01-22 |
Medarex, Inc. |
Methods and compositions for preventing oxidative degradation of proteins
|
|
US20070185017A1
(en)
|
2002-10-29 |
2007-08-09 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
CN1753912B
(zh)
|
2002-12-23 |
2011-11-02 |
惠氏公司 |
抗pd-1抗体及其用途
|
|
WO2005035732A2
(en)
|
2003-02-19 |
2005-04-21 |
Dyax Corporation |
Papp-a ligands
|
|
FI1897548T4
(fi)
|
2003-02-28 |
2024-09-03 |
The Johns Hopkins University |
T-solujen säätely
|
|
CA2541360A1
(en)
|
2003-10-08 |
2005-04-21 |
Bradley T. Messmer |
Methods and compositions for diagnosis and treatment of b cell chronic lymphocytic leukemia
|
|
NZ547157A
(en)
|
2003-12-10 |
2009-07-31 |
Medarex Inc |
Interferon Alpha Antibodies and their uses
|
|
MX350383B
(es)
|
2004-01-09 |
2017-09-04 |
Pfizer |
Anticuerpos contra madcam.
|
|
KR100891620B1
(ko)
|
2004-04-13 |
2009-04-02 |
에프. 호프만-라 로슈 아게 |
항-p-셀렉틴 항체
|
|
WO2005103081A2
(en)
|
2004-04-20 |
2005-11-03 |
Genmab A/S |
Human monoclonal antibodies against cd20
|
|
KR20070038556A
(ko)
|
2004-07-20 |
2007-04-10 |
심포젠 에이/에스 |
항-rhesus d 재조합 폴리클로날 항체 및 이의 제조방법
|
|
CA2575791A1
(en)
|
2004-08-03 |
2006-02-16 |
Dyax Corp. |
Hk1-binding proteins
|
|
US20090252741A1
(en)
|
2004-09-08 |
2009-10-08 |
Ohio State University Research Foundation |
Human monoclonal anti-ctla4 antibodies in cancer treatment
|
|
WO2006039644A2
(en)
|
2004-10-01 |
2006-04-13 |
Medarex, Inc. |
Methods of treating cd30 positive lymphomas
|
|
ES2671893T3
(es)
|
2004-10-06 |
2018-06-11 |
Mayo Foundation For Medical Education And Research |
B7-H1 y PD-1 en el tratamiento del carcinoma de células renales
|
|
JO3000B1
(ar)
*
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
WO2006101691A1
(en)
|
2005-03-23 |
2006-09-28 |
Pfizer Products Inc. |
Therapy of prostate cancer with ctla4 antibodies and hormonal therapy
|
|
RU2494107C2
(ru)
|
2005-05-09 |
2013-09-27 |
Оно Фармасьютикал Ко., Лтд. |
Моноклональные антитела человека к белку программируемой смерти 1 (pd-1) и способы лечения рака с использованием анти-pd-1-антител самостоятельно или в комбинации с другими иммунотерапевтическими средствами
|
|
CN101355965A
(zh)
|
2005-06-08 |
2009-01-28 |
达纳-法伯癌症研究院 |
通过抑制程序性细胞死亡1(pd-1)途经治疗持续性感染和癌症的方法及组合物
|
|
CN104356236B
(zh)
|
2005-07-01 |
2020-07-03 |
E.R.施贵宝&圣斯有限责任公司 |
抗程序性死亡配体1(pd-l1)的人单克隆抗体
|
|
EP1777523A1
(en)
|
2005-10-19 |
2007-04-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method
|
|
EP1957531B1
(en)
|
2005-11-07 |
2016-04-13 |
Genentech, Inc. |
Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
|
|
EP2314619A1
(en)
|
2005-12-05 |
2011-04-27 |
Symphogen A/S |
Anti-orthopoxvirus recombinant polyclonal antibody
|
|
CN101490085A
(zh)
|
2006-06-12 |
2009-07-22 |
特鲁比昂药品公司 |
具有效应功能的单链多价结合蛋白
|
|
WO2007146968A2
(en)
|
2006-06-12 |
2007-12-21 |
Trubion Pharmaceuticals, Inc. |
Single-chain multivalent binding proteins with effector function
|
|
EP2975057A1
(en)
|
2006-07-10 |
2016-01-20 |
Fujita Health University |
Novel anti-cd73 antibody
|
|
WO2008073160A2
(en)
|
2006-08-17 |
2008-06-19 |
The Trustees Of Columbia University In The City Of New York |
Methods for converting or inducing protective immunity
|
|
AR062435A1
(es)
|
2006-08-18 |
2008-11-05 |
Xoma Technology Ltd |
Anticuerpo especifico prlr (receptor de prolactina) y sus usos
|
|
CA2682292A1
(en)
|
2007-03-30 |
2008-10-09 |
Medimmune, Llc |
Aqueous formulation comprising an anti-human interferon alpha antibody
|
|
EP1987839A1
(en)
|
2007-04-30 |
2008-11-05 |
I.N.S.E.R.M. Institut National de la Sante et de la Recherche Medicale |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
|
HRP20131167T1
(hr)
|
2007-06-18 |
2014-01-03 |
Merck Sharp & Dohme B.V. |
Antitijela za humani receptor programirane smrti pd-1
|
|
US20090028857A1
(en)
|
2007-07-23 |
2009-01-29 |
Cell Genesys, Inc. |
Pd-1 antibodies in combination with a cytokine-secreting cell and methods of use thereof
|
|
US8476419B2
(en)
|
2007-09-14 |
2013-07-02 |
Vrije Universiteit Brussel |
Enhancing the T-cells stimulatory capacity of human antigen presenting cells and their use in vaccination
|
|
EP2044949A1
(en)
|
2007-10-05 |
2009-04-08 |
Immutep |
Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response
|
|
WO2009114335A2
(en)
|
2008-03-12 |
2009-09-17 |
Merck & Co., Inc. |
Pd-1 binding proteins
|
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
|
CN102203132A
(zh)
|
2008-08-25 |
2011-09-28 |
安普利穆尼股份有限公司 |
Pd-1拮抗剂的组合物和使用方法
|
|
AU2009333580B2
(en)
|
2008-12-09 |
2016-07-07 |
Genentech, Inc. |
Anti-PD-L1 antibodies and their use to enhance T-cell function
|
|
US20110007023A1
(en)
|
2009-07-09 |
2011-01-13 |
Sony Ericsson Mobile Communications Ab |
Display device, touch screen device comprising the display device, mobile device and method for sensing a force on a display device
|
|
SI2454284T1
(en)
|
2009-07-15 |
2018-07-31 |
Aimm Therapeutics B.V. |
Compounds that specifically bind to Gram-positive bacteria
|
|
NZ628923A
(en)
|
2009-11-24 |
2016-02-26 |
Medimmune Ltd |
Targeted binding agents against b7-h1
|
|
US8907053B2
(en)
|
2010-06-25 |
2014-12-09 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
|
CA2805414C
(en)
|
2010-07-14 |
2020-07-07 |
Merck Sharp & Dohme Corp. |
Anti-addl monoclonal antibody and uses thereof
|
|
WO2012054438A1
(en)
|
2010-10-22 |
2012-04-26 |
Schering Corporation |
Anti-pcsk9
|
|
JP6033783B2
(ja)
|
2010-11-01 |
2016-11-30 |
シムフォゲン・アクティーゼルスカブSymphogen A/S |
Pan−her抗体組成物
|
|
KR101970025B1
(ko)
|
2011-04-20 |
2019-04-17 |
메디뮨 엘엘씨 |
B7-h1 및 pd-1과 결합하는 항체 및 다른 분자들
|
|
JP6240600B2
(ja)
|
2011-07-24 |
2017-11-29 |
キュアテク リミテッド |
ヒト化免疫モノクローナル抗体の変異体
|
|
CA2853637C
(en)
|
2011-10-26 |
2023-04-04 |
Novartis Ag |
Anti-canine cd20 monoclonal antibodies and methods of use
|
|
HRP20201595T1
(hr)
|
2011-11-28 |
2020-12-11 |
Merck Patent Gmbh |
Anti-pd-l1 protutijela i njihova uporaba
|
|
CN113967253A
(zh)
|
2012-05-15 |
2022-01-25 |
百时美施贵宝公司 |
通过破坏pd-1/pd-l1信号传输的免疫治疗
|
|
HK1204557A1
(en)
|
2012-05-31 |
2015-11-27 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind pd-l1
|
|
AR091649A1
(es)
|
2012-07-02 |
2015-02-18 |
Bristol Myers Squibb Co |
Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
|
|
EA037554B1
(ru)
|
2013-03-15 |
2021-04-13 |
Глаксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед |
Анти-lag-3 связывающие белки
|
|
WO2014144666A2
(en)
|
2013-03-15 |
2014-09-18 |
The University Of Chicago |
Methods and compositions related to t-cell activity
|
|
JP6742903B2
(ja)
|
2013-05-02 |
2020-08-19 |
アナプティスバイオ インコーポレイティッド |
プログラム死−1(pd−1)に対する抗体
|
|
US9676853B2
(en)
|
2013-05-31 |
2017-06-13 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind PD-1
|
|
CN104250302B
(zh)
|
2013-06-26 |
2017-11-14 |
上海君实生物医药科技股份有限公司 |
抗pd‑1抗体及其应用
|
|
CA2917858A1
(en)
|
2013-08-02 |
2015-02-05 |
Aduro Biotech Holdings, Europe B.V. |
Combining cd27 agonists and immune checkpoint inhibition for immune stimulation
|
|
EA034666B1
(ru)
|
2013-09-13 |
2020-03-04 |
Бейджин Свитзерланд Гмбх |
Антитело против pd-1 и его применение для лечения рака или вирусной инфекции и фрагмент антитела
|
|
SG11201601763SA
(en)
|
2013-09-20 |
2016-04-28 |
Bristol Myers Squibb Co |
Combination of anti-lag-3 antibodies and anti-pd-1 antibodies to treat tumors
|
|
MY184154A
(en)
|
2013-12-12 |
2021-03-23 |
Shanghai hengrui pharmaceutical co ltd |
Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof
|
|
EP3084005A4
(en)
|
2013-12-17 |
2017-08-02 |
Merck Sharp & Dohme Corp. |
Pd-l1 gene signature biomarkers of tumor response to pd-1 antagonists
|
|
WO2015094995A2
(en)
|
2013-12-17 |
2015-06-25 |
Merck Sharp & Dohme Corp. |
Gene signature biomarkers of tumor response to pd-1 antagonists
|
|
WO2015095404A2
(en)
|
2013-12-17 |
2015-06-25 |
Genentech, Inc. |
Methods of treating cancers using pd-1 axis binding antagonists and taxanes
|
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
|
SG10201900002QA
(en)
|
2014-01-24 |
2019-02-27 |
Dana Farber Cancer Institue Inc |
Antibody molecules to pd-1 and uses thereof
|
|
EP3099716A1
(en)
|
2014-01-28 |
2016-12-07 |
Bristol-Myers Squibb Company |
Anti-lag-3 antibodies to treat hematological malignancies
|
|
US20150259420A1
(en)
|
2014-03-14 |
2015-09-17 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
|
EP3144388B1
(en)
|
2014-05-13 |
2020-07-01 |
Chugai Seiyaku Kabushiki Kaisha |
T cell-redirecting antigen-binding molecule for cells having immunosuppression function
|
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
|
JO3663B1
(ar)
|
2014-08-19 |
2020-08-27 |
Merck Sharp & Dohme |
الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
|
|
KR20170072343A
(ko)
|
2014-11-06 |
2017-06-26 |
제넨테크, 인크. |
Ox40 결합 효능제 및 tigit 억제제를 포함하는 병용 요법
|
|
EP3916017A1
(en)
|
2014-12-22 |
2021-12-01 |
PD-1 Acquisition Group, LLC |
Anti-pd-1 antibodies
|
|
GB201500374D0
(en)
|
2015-01-09 |
2015-02-25 |
Immutep S A |
Combined preparations for the treatment of cancer
|
|
MA41463A
(fr)
|
2015-02-03 |
2017-12-12 |
Anaptysbio Inc |
Anticorps dirigés contre le gène d'activation 3 des lymphocytes (lag-3)
|
|
US20190041389A1
(en)
|
2015-02-13 |
2019-02-07 |
The University Of Queensland |
Methods for classifying tumors and uses therefor
|
|
CN108112254B
(zh)
|
2015-03-13 |
2022-01-28 |
西托姆克斯治疗公司 |
抗-pdl1抗体、可活化的抗-pdl1抗体、及其使用方法
|
|
TN2017000440A1
(en)
|
2015-04-17 |
2019-04-12 |
Bristol Myers Squibb Co |
Compositions comprising a combination of an anti-pd-1 antibody and another antibody
|
|
US20160362489A1
(en)
|
2015-04-28 |
2016-12-15 |
Bristol-Myers Squibb Company |
Treatment of PD-L1-Positive Melanoma Using an Anti-PD-1 Antibody
|
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
|
WO2016197367A1
(en)
|
2015-06-11 |
2016-12-15 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-pd-l1 antibodies
|
|
WO2017004153A1
(en)
|
2015-06-29 |
2017-01-05 |
The Broad Institute Inc. |
Tumor and microenvironment gene expression, compositions of matter and methods of use thereof
|
|
EP3316888A1
(en)
|
2015-07-02 |
2018-05-09 |
Celgene Corporation |
Combination therapy for treatment of hematological cancers and solid tumors
|
|
GB201512869D0
(en)
|
2015-07-21 |
2015-09-02 |
Almac Diagnostics Ltd |
Gene signature for minute therapies
|
|
CA2993177A1
(en)
|
2015-07-22 |
2017-01-26 |
Sorrento Therapeutics, Inc. |
Antibody therapeutics that bind lag3
|
|
DK3317301T3
(da)
|
2015-07-29 |
2021-06-28 |
Immutep Sas |
Kombinationsterapier omfattende antistofmolekyler mod lag-3
|
|
WO2017019846A1
(en)
|
2015-07-30 |
2017-02-02 |
Macrogenics, Inc. |
Pd-1-binding molecules and methods use thereof
|
|
WO2017020291A1
(en)
|
2015-08-06 |
2017-02-09 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-pd-l1 antibodies
|
|
WO2017025498A1
(en)
|
2015-08-07 |
2017-02-16 |
Pieris Pharmaceuticals Gmbh |
Novel fusion polypeptide specific for lag-3 and pd-1
|
|
WO2017024465A1
(en)
|
2015-08-10 |
2017-02-16 |
Innovent Biologics (Suzhou) Co., Ltd. |
Pd-1 antibodies
|
|
WO2017024515A1
(en)
|
2015-08-11 |
2017-02-16 |
Wuxi Biologics (Cayman) Inc. |
Novel anti-pd-1 antibodies
|
|
KR102055396B1
(ko)
|
2015-08-11 |
2019-12-12 |
우시 바이올로직스 (케이만) 인코포레이티드 |
신규한 항-pd-1 항체
|
|
AR105654A1
(es)
|
2015-08-24 |
2017-10-25 |
Lilly Co Eli |
Anticuerpos pd-l1 (ligando 1 de muerte celular programada)
|
|
CN114605548A
(zh)
|
2015-09-01 |
2022-06-10 |
艾吉纳斯公司 |
抗-pd-1抗体及其使用方法
|
|
KR20250073532A
(ko)
|
2015-09-02 |
2025-05-27 |
이뮤텝 에스.에이.에스. |
항-lag-3 항체
|
|
TWI756187B
(zh)
|
2015-10-09 |
2022-03-01 |
美商再生元醫藥公司 |
抗lag3抗體及其用途
|
|
US10705088B2
(en)
|
2015-10-23 |
2020-07-07 |
Novartis Ag |
Method of scoring a sample comprising tumor tissue
|
|
DK3827845T3
(da)
*
|
2015-11-03 |
2022-05-23 |
Janssen Biotech Inc |
Subkutane formuleringer af anti-cd38-antistoffer og anvendelser deraf
|
|
US11660340B2
(en)
|
2015-11-18 |
2023-05-30 |
Chugai Seiyaku Kabushiki Kaisha |
Combination therapy using T cell redirection antigen binding molecule against cell having immunosuppressing function
|
|
CN106699889A
(zh)
|
2015-11-18 |
2017-05-24 |
礼进生物医药科技(上海)有限公司 |
抗pd-1抗体及其治疗用途
|
|
WO2017086419A1
(ja)
|
2015-11-18 |
2017-05-26 |
中外製薬株式会社 |
液性免疫応答の増強方法
|
|
MA43260A
(fr)
|
2015-11-18 |
2018-09-26 |
Merck Sharp & Dohme |
Liants pd1 et/ou lag3
|
|
WO2017087901A2
(en)
|
2015-11-19 |
2017-05-26 |
Sutro Biopharma, Inc. |
Anti-lag3 antibodies, compositions comprising anti-lag3 antibodies and methods of making and using anti-lag3 antibodies
|
|
BR112018010172A2
(pt)
|
2015-11-19 |
2018-11-21 |
Bristol Myers Squibb Co |
anticorpos contra receptor de fator de necrose de tumor induzido por glicocorticoide (gitr) e usos dos mesmos
|
|
US10969392B2
(en)
|
2015-12-10 |
2021-04-06 |
Vanderbilt University |
Methods and systems for predicting response to immunotherapies for treatment of cancer
|
|
US10954301B2
(en)
|
2015-12-14 |
2021-03-23 |
Macrogenics, Inc. |
Bispecific molecules having immunoreactivity with PD-1 and CTLA-4, and methods of use thereof
|
|
KR20180086502A
(ko)
|
2015-12-16 |
2018-07-31 |
머크 샤프 앤드 돔 코포레이션 |
항-lag3 항체 및 항원-결합 단편
|
|
MX2018007295A
(es)
|
2016-01-11 |
2019-03-28 |
Armo Biosciences Inc |
Interleucina 10 en la produccion de linfocitos t cd8+especificos para el antigeno y metodos de uso de estos.
|
|
CN111491361B
(zh)
|
2016-02-02 |
2023-10-24 |
华为技术有限公司 |
确定发射功率的方法、用户设备和基站
|
|
WO2017132827A1
(en)
|
2016-02-02 |
2017-08-10 |
Innovent Biologics (Suzhou) Co., Ltd. |
Pd-1 antibodies
|
|
SG10201601719RA
(en)
|
2016-03-04 |
2017-10-30 |
Agency Science Tech & Res |
Anti-LAG-3 Antibodies
|
|
AU2017266298B2
(en)
|
2016-05-18 |
2024-01-04 |
Boehringer Ingelheim International Gmbh |
Anti PD-1 and anti-LAG3 antibodies for cancer treatment
|
|
KR102664891B1
(ko)
|
2016-06-20 |
2024-05-13 |
에프-스타 테라퓨틱스 리미티드 |
Pd-l1 및 lag-3에 결합하는 결합 분자
|
|
KR20190022632A
(ko)
|
2016-06-20 |
2019-03-06 |
에프-스타 베타 리미티드 |
Lag-3 결합 구성원
|
|
CA3024359A1
(en)
|
2016-06-23 |
2017-12-28 |
Jiangsu Hengrui Medicine Co., Ltd. |
Lag-3 antibody, antigen-binding fragment thereof, and pharmaceutical application thereof
|
|
EP3498840A4
(en)
|
2016-08-15 |
2020-05-06 |
National University Corporation Hokkaido University |
ANTI-LAG-3 ANTIBODY
|
|
WO2018057506A1
(en)
|
2016-09-20 |
2018-03-29 |
Medimmune, Llc |
Compositions and methods for characterizing solid tumors responsiveness to anti-pd-l1 antibody monotherapy
|
|
SG10201912663YA
(en)
|
2016-10-11 |
2020-03-30 |
Agenus Inc |
Anti-lag-3 antibodies and methods of use thereof
|
|
CA3040194A1
(en)
|
2016-10-13 |
2018-04-19 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for predicting response and resistance to ctla4 blockade in melanoma using a gene expression signature
|
|
MY203971A
(en)
|
2016-10-13 |
2024-07-26 |
Chia Tai Tianqing Pharmaceutical Group Co Ltd |
Anti-lag-3 antibodies and compositions
|
|
WO2018083087A2
(en)
|
2016-11-02 |
2018-05-11 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Binding proteins
|
|
EP3615572A1
(en)
|
2017-04-27 |
2020-03-04 |
Tesaro Inc. |
Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof
|
|
AU2018263868A1
(en)
|
2017-05-02 |
2019-12-12 |
Merck Sharp & Dohme Llc |
Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies
|
|
CN110621337B
(zh)
|
2017-05-10 |
2021-11-09 |
浙江时迈药业有限公司 |
抗lag3人单克隆抗体及其用途
|
|
JP2020521759A
(ja)
|
2017-05-26 |
2020-07-27 |
ザ・ジョンズ・ホプキンス・ユニバーシティ |
免疫トレランスを調節するための多機能性の抗体−リガンド・トラップ
|
|
SMT202300418T1
(it)
|
2017-05-30 |
2024-01-10 |
Bristol Myers Squibb Co |
Trattamento di tumori positivi per lag-3
|
|
EP3630179A2
(en)
|
2017-05-30 |
2020-04-08 |
Bristol-Myers Squibb Company |
Compositions comprising an anti-lag-3 antibody or an anti-lag-3 antibody and an anti-pd-1 or anti-pd-l1 antibody
|
|
US20210340250A1
(en)
|
2017-05-30 |
2021-11-04 |
Bristol-Myers Squibb Company |
Compositions comprising a combination of an anti-lag-3 antibody, a pd-1 pathway inhibitor, and an immunotherapeutic agent
|
|
MX2021000726A
(es)
|
2018-07-26 |
2021-03-25 |
Bristol Myers Squibb Co |
Terapia combinada de gen de activacion de linfocitos 3(lag-3) para el tratamiento del cancer.
|
|
JP2022512750A
(ja)
|
2018-10-19 |
2022-02-07 |
ブリストル-マイヤーズ スクイブ カンパニー |
黒色腫に対する併用療法
|