JP2019509737A5 - - Google Patents
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- JP2019509737A5 JP2019509737A5 JP2018547346A JP2018547346A JP2019509737A5 JP 2019509737 A5 JP2019509737 A5 JP 2019509737A5 JP 2018547346 A JP2018547346 A JP 2018547346A JP 2018547346 A JP2018547346 A JP 2018547346A JP 2019509737 A5 JP2019509737 A5 JP 2019509737A5
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- Prior art keywords
- antibody
- tgfβ1
- antigen
- pharmaceutical composition
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021174552A JP2022028680A (ja) | 2016-03-11 | 2021-10-26 | ＴＧＦβ１結合性免疫グロブリンおよびその使用 |
| JP2021209374A JP7794630B2 (ja) | 2016-03-11 | 2021-12-23 | ＴＧＦβ１結合性免疫グロブリンおよびその使用 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662307353P | 2016-03-11 | 2016-03-11 | |
| US62/307,353 | 2016-03-11 | ||
| US201762443615P | 2017-01-06 | 2017-01-06 | |
| US62/443,615 | 2017-01-06 | ||
| US201762452866P | 2017-01-31 | 2017-01-31 | |
| US62/452,866 | 2017-01-31 | ||
| PCT/US2017/021972 WO2017156500A1 (en) | 2016-03-11 | 2017-03-10 | Tgfb1-binding immunoglobulins and use thereof |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021174552A Division JP2022028680A (ja) | 2016-03-11 | 2021-10-26 | ＴＧＦβ１結合性免疫グロブリンおよびその使用 |
| JP2021209374A Division JP7794630B2 (ja) | 2016-03-11 | 2021-12-23 | ＴＧＦβ１結合性免疫グロブリンおよびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019509737A JP2019509737A (ja) | 2019-04-11 |
| JP2019509737A5 true JP2019509737A5 (https=) | 2020-04-16 |
Family
ID=58503696
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018547346A Withdrawn JP2019509737A (ja) | 2016-03-11 | 2017-03-10 | ＴＧＦβ１結合性免疫グロブリンおよびその使用 |
| JP2021174552A Withdrawn JP2022028680A (ja) | 2016-03-11 | 2021-10-26 | ＴＧＦβ１結合性免疫グロブリンおよびその使用 |
| JP2021209374A Active JP7794630B2 (ja) | 2016-03-11 | 2021-12-23 | ＴＧＦβ１結合性免疫グロブリンおよびその使用 |
| JP2023100034A Withdrawn JP2023108057A (ja) | 2016-03-11 | 2023-06-19 | ＴＧＦβ１結合性免疫グロブリンおよびその使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021174552A Withdrawn JP2022028680A (ja) | 2016-03-11 | 2021-10-26 | ＴＧＦβ１結合性免疫グロブリンおよびその使用 |
| JP2021209374A Active JP7794630B2 (ja) | 2016-03-11 | 2021-12-23 | ＴＧＦβ１結合性免疫グロブリンおよびその使用 |
| JP2023100034A Withdrawn JP2023108057A (ja) | 2016-03-11 | 2023-06-19 | ＴＧＦβ１結合性免疫グロブリンおよびその使用 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US11643459B2 (https=) |
| EP (2) | EP3365368B1 (https=) |
| JP (4) | JP2019509737A (https=) |
| KR (3) | KR20180122397A (https=) |
| CN (1) | CN109071646A (https=) |
| AU (2) | AU2017230103A1 (https=) |
| BR (1) | BR112018068340A2 (https=) |
| CA (1) | CA3055555A1 (https=) |
| DK (1) | DK3365368T3 (https=) |
| EA (1) | EA201891909A1 (https=) |
| ES (1) | ES2951648T3 (https=) |
| FI (1) | FI3365368T3 (https=) |
| HU (1) | HUE062976T2 (https=) |
| IL (2) | IL307835A (https=) |
| MX (2) | MX2018010948A (https=) |
| PL (1) | PL3365368T3 (https=) |
| PT (1) | PT3365368T (https=) |
| SG (1) | SG11201807176XA (https=) |
| WO (1) | WO2017156500A1 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017156500A1 (en) | 2016-03-11 | 2017-09-14 | Scholar Rock, Inc. | Tgfb1-binding immunoglobulins and use thereof |
| US20190292254A1 (en) * | 2016-07-14 | 2019-09-26 | Scholar Rock, Inc. | TGFBeta Antibodies, Methods and Uses |
| PE20191661A1 (es) | 2017-01-06 | 2019-11-11 | Scholar Rock Inc | Inhibidores de tgf beta1 isoforma-especificos contexto-permisivos y uso de los mismos |
| EP3600322A1 (en) * | 2017-03-28 | 2020-02-05 | Boehringer Ingelheim International GmbH | Nintedanib for use in methods for the treatment of muscular dystrophy |
| PT3621694T (pt) | 2017-05-09 | 2023-10-09 | Scholar Rock Inc | Inibidores de lrrc33 e sua utilização |
| US12358992B2 (en) * | 2017-07-28 | 2025-07-15 | Scholar Rock, Inc. | LTBP complex-specific inhibitors of TGF-beta 1 and uses thereof |
| EP3694552A1 (en) | 2017-10-10 | 2020-08-19 | Tilos Therapeutics, Inc. | Anti-lap antibodies and uses thereof |
| US20210115122A1 (en) * | 2018-02-23 | 2021-04-22 | Chugai Seiyaku Kabushiki Kaisha | Cross-species anti-latent tgf-beta 1 antibodies and methods of use |
| TW202019957A (zh) | 2018-07-11 | 2020-06-01 | 美商供石公司 | TGFβ1抑制劑及其用途 |
| MX2021000347A (es) | 2018-07-11 | 2021-04-19 | Scholar Rock Inc | Inhibidores de tgf?1 selectivos de isoforma, de alta afinidad y usos de los mismos. |
| PL3677278T3 (pl) | 2018-07-11 | 2022-02-28 | Scholar Rock, Inc. | Selektywne względem izoformy inhibitory tgfbeta1 i ich zastosowanie |
| EP3863722A2 (en) | 2018-10-10 | 2021-08-18 | Tilos Theapeutics, Inc. | Anti-lap antibody variants and uses thereof |
| WO2020095113A1 (en) * | 2018-11-05 | 2020-05-14 | Ludwig Institute For Cancer Research Ltd | Humanized and variant tgf-beta1 specific antibodies and methods and uses thereof |
| AR117918A1 (es) | 2019-01-30 | 2021-09-01 | Scholar Rock Inc | COMPLEJOS-ESPECÍFICOS LTBP INHIBIDORES DE TGFb Y SUS USOS |
| CA3135988C (en) * | 2019-06-10 | 2024-11-19 | Shandong Boan Biotechnology Co., Ltd. | Bifunctional fusion protein against PD-L1 and TGFS and its use |
| BR112022003412A2 (pt) | 2019-08-28 | 2022-05-24 | Chugai Pharmaceutical Co Ltd | Anticorpos anti-tgf-beta 1 latente de espécies cruzadas e métodos de uso |
| AU2021205440A1 (en) | 2020-01-11 | 2022-09-01 | Scholar Rock,Inc. | TGF-beta inhibitors and use thereof |
| US20230057012A1 (en) | 2020-01-11 | 2023-02-23 | Scholar Rock, Inc. | Tgfb inhibitors and use thereof |
| EP4126919A1 (en) * | 2020-03-24 | 2023-02-08 | Bio-Techne Corporation | Methods of using a tgf beta knockout cell line and compositions resulting therefrom |
| CA3208624A1 (en) * | 2021-01-18 | 2022-07-21 | Shanghai Jemincare Pharmaceutical Co., Ltd. | Garp protein antibody and application thereof |
| JP7280400B2 (ja) * | 2021-02-26 | 2023-05-23 | 中外製薬株式会社 | 種交差性抗潜在型ＴＧＦ－β１抗体の使用 |
| WO2022180764A1 (en) | 2021-02-26 | 2022-09-01 | Chugai Seiyaku Kabushiki Kaisha | Uses of cross-species anti-latent tgf-beta 1 antibodies |
| WO2022204581A2 (en) | 2021-03-26 | 2022-09-29 | Scholar Rock, Inc. | Tgf-beta inhibitors and use thereof |
| WO2022206753A1 (zh) * | 2021-03-29 | 2022-10-06 | 山东先声生物制药有限公司 | GARP/TGFβ1抗体及其应用 |
| WO2022256723A2 (en) | 2021-06-03 | 2022-12-08 | Scholar Rock, Inc. | Tgf-beta inhibitors and therapeutic use thereof |
| EP4370148A1 (en) | 2021-07-14 | 2024-05-22 | Scholar Rock, Inc. | Ltbp complex-specific inhibitors of tgf beta1 and uses thereof |
| CA3244596A1 (en) | 2022-03-29 | 2023-10-05 | Allogene Therapeutics, Inc. | Chimeric switch receivers for converting immunoactive signals into stimulation signals |
| WO2024023283A1 (en) | 2022-07-29 | 2024-02-01 | Institut National de la Santé et de la Recherche Médicale | Lrrc33 as a biomarker and biotarget in cutaneous t-cell lymphomas |
| GB202219154D0 (en) * | 2022-12-19 | 2023-02-01 | Metacurum Biotech Ab | Antibodies and uses thereof |
| WO2024149237A1 (zh) * | 2023-01-09 | 2024-07-18 | 北京拓界生物医药科技有限公司 | TGFβ1结合分子、GARP-TGFβ1结合分子及其医药用途 |
| PE20252310A1 (es) | 2023-02-10 | 2025-09-22 | Chugai Pharmaceutical Co Ltd | Anticuerpos anti-tgf-beta 1 latente y metodos de uso |
| WO2024187051A1 (en) | 2023-03-07 | 2024-09-12 | Scholar Rock, Inc. | Tgf-beta inhibitors for use for treating resistant or unresponsive cancer in patients |
| WO2025240343A1 (en) | 2024-05-13 | 2025-11-20 | Scholar Rock, Inc. | Tgf-beta inhibitors for treating cancer |
| CN120131938B (zh) * | 2025-03-19 | 2025-12-23 | 广州奥奇生物技术有限公司 | 一种益生菌制剂的制备方法及其在改善睡眠中的应用 |
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