|
ATE92501T1
(de)
|
1984-10-04 |
1993-08-15 |
Sandoz Ag |
Monoklonale antikoerper gegen zyklosporine.
|
|
DE69013742T2
(de)
|
1989-04-15 |
1995-03-23 |
Fujirebio Kk |
Peptide und diese Peptide enthaltende Wirkstoffe gegen Dementia.
|
|
ES2089723T3
(es)
|
1992-03-27 |
1996-10-01 |
American Home Prod |
29-demetoxirapamicina para inducir la inmunodepresion.
|
|
DK0725778T3
(da)
|
1993-09-20 |
2001-12-17 |
Univ Leland Stanford Junior |
Rekombinant produktion af hidtil ukendte polyketider
|
|
IL112873A
(en)
|
1994-03-08 |
2005-03-20 |
Wyeth Corp |
Rapamycin-fkbp12 binding proteins, their isolation and their use
|
|
GB9410142D0
(en)
|
1994-05-20 |
1994-07-06 |
Univ Warwick |
Carbapenems
|
|
GB9524630D0
(en)
|
1994-12-24 |
1996-01-31 |
Zeneca Ltd |
Chemical compounds
|
|
US6124453A
(en)
|
1995-07-04 |
2000-09-26 |
Novartis Ag |
Macrolides
|
|
CA2197524A1
(en)
*
|
1996-02-22 |
1997-08-22 |
Bradley Stuart Dehoff |
Polyketide synthase genes
|
|
EP0910633B1
(en)
|
1996-07-05 |
2009-12-09 |
Biotica Technology Limited |
Hybrid polyketide synthase I gene
|
|
SE9603465D0
(sv)
|
1996-09-23 |
1996-09-23 |
Astra Ab |
New compounds
|
|
US6902913B2
(en)
|
1997-04-30 |
2005-06-07 |
Kosan Biosciences, Inc. |
Recombinant narbonolide polyketide synthase
|
|
US6153383A
(en)
|
1997-12-09 |
2000-11-28 |
Verdine; Gregory L. |
Synthetic transcriptional modulators and uses thereof
|
|
ATE473759T1
(de)
|
1998-05-22 |
2010-07-15 |
Univ Leland Stanford Junior |
Bifunktionelle moleküle sowie darauf basierende therapien.
|
|
CA2343880C
(en)
|
1998-10-02 |
2008-08-26 |
Kosan Biosciences, Inc. |
Polyketide synthase enzymes and recombinant dna constructs therefor
|
|
US6686454B1
(en)
|
1998-10-09 |
2004-02-03 |
Isotechnika, Inc. |
Antibodies to specific regions of cyclosporine related compounds
|
|
CA2359801A1
(en)
|
1999-02-09 |
2000-08-17 |
Rajesh S. Gokhale |
Methods to mediate polyketide synthase module effectiveness
|
|
GB9927191D0
(en)
|
1999-11-17 |
2000-01-12 |
Angeletti P Ist Richerche Bio |
Methods and means for regulation of gene expression
|
|
EP1230353A4
(en)
|
1999-11-19 |
2002-11-06 |
Univ Leland Stanford Junior |
BIFUNCTIONAL MOLECULES AND THEIR USE IN THE DESTRUCTION OF PROTEIN-PROTEIN INTERACTIONS
|
|
US7220552B1
(en)
|
1999-11-19 |
2007-05-22 |
The Board Of Trustees Of The Leland Stanford Junior University |
Bifunctional molecules and their use in the disruption of protein-protein interactions
|
|
WO2001059126A2
(en)
*
|
2000-02-08 |
2001-08-16 |
Norges Teknisk Naturvitenskapelige Universitet |
Gene cluster encoding a nystatin polyketide synthase and its manipulation and utility
|
|
MXPA02000823A
(es)
|
2000-05-23 |
2002-07-30 |
Vertex Pharma |
Inhibidores de caspasa y uso de los mismos.
|
|
US7198924B2
(en)
*
|
2000-12-11 |
2007-04-03 |
Invitrogen Corporation |
Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
|
|
US20030153053A1
(en)
*
|
2001-08-06 |
2003-08-14 |
Ralph Reid |
Methods for altering polyketide synthase genes
|
|
US6809077B2
(en)
|
2001-10-12 |
2004-10-26 |
Enanta Pharmaceuticals, Inc. |
Cyclosporin analogs for the treatment of autoimmune diseases
|
|
US6987090B2
(en)
|
2002-05-09 |
2006-01-17 |
Lg Household & Health Care Ltd. |
Use of 3-position cyclosporin derivatives for hair growth
|
|
EP1477563A3
(en)
*
|
2003-05-16 |
2004-11-24 |
Wyeth |
Cloning genes from streptomyces cyaneogriseus subsp.noncyanogenus for biosynthesis of antibiotics and methods of use
|
|
JP2009528292A
(ja)
|
2006-02-27 |
2009-08-06 |
ザ ボード オブ トラスティーズ オブ レランド スタンフォード ジュニア ユニバーシティ |
生物学的障壁を越える増強された放出特性を有する分子の輸送のための組成物および方法
|
|
US20070203168A1
(en)
|
2006-02-28 |
2007-08-30 |
Zhao Jonathon Z |
Isomers of rapamycin and 42-Epi-rapamycin, methods of making and using the same
|
|
KR100945483B1
(ko)
|
2007-10-25 |
2010-03-05 |
이화여자대학교 산학협력단 |
pikD 조절유전자의 발현벡터를 이용한 스트렙토미세스베네주엘라에(Streptomycesvenezuelae)에서폴리케타이드(polyketide)의 생산성 증가방법
|
|
GB0805363D0
(en)
*
|
2008-03-20 |
2008-04-30 |
Sinvent As |
Novel NRPS-PKS gene cluster and its manipulation and utility
|
|
WO2010031185A1
(en)
|
2008-09-19 |
2010-03-25 |
Protox Therapeutics Inc. |
Treating cancer stem cells using targeted cargo proteins
|
|
US8962329B2
(en)
|
2008-09-24 |
2015-02-24 |
Shanghai Institute Of Organic Chemistry, Chinese Academy Of Sciences |
Gene cluster
|
|
WO2010088573A1
(en)
|
2009-01-30 |
2010-08-05 |
Enanta Pharmaceuticals, Inc. |
Cyclosporin analogues for preventing or treating hepatitis c infection
|
|
WO2011008260A2
(en)
|
2009-07-13 |
2011-01-20 |
President And Fellows Of Harvard College |
Bifunctional stapled polypeptides and uses thereof
|
|
WO2011009938A2
(en)
|
2009-07-24 |
2011-01-27 |
Universite Henri Poincare Nancy 1 |
Stambomycin and derivatives, their production and their use as drugs
|
|
AU2010298338A1
(en)
|
2009-09-22 |
2012-04-12 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles
|
|
EP2492344B1
(en)
|
2009-10-22 |
2016-04-06 |
PeptiDream Inc. |
Rapid display method in translational synthesis of peptide
|
|
EP2646440A4
(en)
|
2010-11-30 |
2014-06-18 |
Univ Johns Hopkins |
CYCLIC HYBRID LIBRARIES AND SCREENS FOR THIS
|
|
US9428845B1
(en)
|
2010-12-28 |
2016-08-30 |
Warp Drive Bio, Inc. |
Identifying new therapeutic agents
|
|
WO2012174489A2
(en)
|
2011-06-15 |
2012-12-20 |
The Ohio State University |
Small molecule composite surfaces as inhibitors of protein-protein interactions
|
|
PL3210627T3
(pl)
|
2012-07-12 |
2023-04-17 |
Hangzhou Dac Biotech Co., Ltd |
Koniugaty zawierające cząsteczki wiążące się z komórką i środek cytotoksyczny
|
|
EP2922818B1
(en)
|
2012-11-24 |
2018-09-05 |
Hangzhou Dac Biotech Co., Ltd |
Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
|
|
EP2806274A1
(en)
|
2013-05-24 |
2014-11-26 |
AIT Austrian Institute of Technology GmbH |
Lung cancer diagnostic method and means
|
|
US10233431B2
(en)
|
2014-02-26 |
2019-03-19 |
The Regents Of The University Of California |
Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases
|
|
CN106255882A
(zh)
|
2014-03-03 |
2016-12-21 |
耶路撒冷希伯来大学伊森姆研究发展公司 |
用于检测铜绿假单胞菌的方法和装置
|
|
WO2018081592A2
(en)
|
2016-10-28 |
2018-05-03 |
Warp Drive Bio, Inc. |
Compositions and methods for the production of compounds
|