AU1776501A - Bifunctional molecules and their use in the disruption of protein-protein interactions - Google Patents

Bifunctional molecules and their use in the disruption of protein-protein interactions

Info

Publication number
AU1776501A
AU1776501A AU17765/01A AU1776501A AU1776501A AU 1776501 A AU1776501 A AU 1776501A AU 17765/01 A AU17765/01 A AU 17765/01A AU 1776501 A AU1776501 A AU 1776501A AU 1776501 A AU1776501 A AU 1776501A
Authority
AU
Australia
Prior art keywords
protein
disruption
bifunctional molecules
interactions
protein interactions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU17765/01A
Inventor
Roger Briesewitz
Gerald R Crabtree
Kryn Stankunas
Thomas Wandless
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Publication of AU1776501A publication Critical patent/AU1776501A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU17765/01A 1999-11-19 2000-11-17 Bifunctional molecules and their use in the disruption of protein-protein interactions Abandoned AU1776501A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16667599P 1999-11-19 1999-11-19
US60166675 1999-11-19
PCT/US2000/031695 WO2001036612A1 (en) 1999-11-19 2000-11-17 Bifunctional molecules and their use in the disruption of protein-protein interactions

Publications (1)

Publication Number Publication Date
AU1776501A true AU1776501A (en) 2001-05-30

Family

ID=22604262

Family Applications (1)

Application Number Title Priority Date Filing Date
AU17765/01A Abandoned AU1776501A (en) 1999-11-19 2000-11-17 Bifunctional molecules and their use in the disruption of protein-protein interactions

Country Status (3)

Country Link
EP (1) EP1230353A4 (en)
AU (1) AU1776501A (en)
WO (1) WO2001036612A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7498025B1 (en) 1999-11-19 2009-03-03 The Board Of Trustees Of The Leland Stanford Junior University Targeted bifunctional molecules and therapies based thereon
US9428845B1 (en) 2010-12-28 2016-08-30 Warp Drive Bio, Inc. Identifying new therapeutic agents
EP3247378B8 (en) * 2015-01-09 2023-08-23 Revolution Medicines, Inc. Macrocyclic compounds that participate in cooperative binding and medical uses thereof
JP7411326B2 (en) 2015-10-01 2024-01-11 ワープ ドライブ バイオ インコーポレイテッド Methods and reagents for analyzing protein-protein interfaces
CA3020594A1 (en) 2016-04-12 2017-10-19 Warp Drive Bio, Inc. Compositions and methods for the production of compounds
US11479797B2 (en) 2016-10-28 2022-10-25 Ginkgo Bioworks, Inc. Compositions and methods for the production of compounds
AU2020379734A1 (en) 2019-11-04 2022-05-05 Revolution Medicines, Inc. Ras inhibitors
MX2022005357A (en) 2019-11-04 2022-06-02 Revolution Medicines Inc Ras inhibitors.
EP4055028A1 (en) 2019-11-04 2022-09-14 Revolution Medicines, Inc. Ras inhibitors
JP2023541916A (en) 2020-09-15 2023-10-04 レボリューション メディシンズ インコーポレイテッド Indole derivatives as RAS inhibitors in the treatment of cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3824633B2 (en) * 1993-02-12 2006-09-20 ザ・ボード・オブ・トラスティーズ・オブ・ザ・リランド・スタンフォード・ジュニアー・ユニバーシティ Regulatory transcription of target genes and other biological consequences
ES2347027T3 (en) * 1998-05-22 2010-10-22 The Board Of Trustees Of The Leland Stanford Junior University BIFUNCTIONAL MOLECULES AND THERAPIES BASED ON THE SAME.

Also Published As

Publication number Publication date
WO2001036612A1 (en) 2001-05-25
EP1230353A4 (en) 2002-11-06
EP1230353A1 (en) 2002-08-14

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase