EP1230353A4 - Bifunctional molecules and their use in the disruption of protein-protein interactions - Google Patents
Bifunctional molecules and their use in the disruption of protein-protein interactionsInfo
- Publication number
- EP1230353A4 EP1230353A4 EP20000980512 EP00980512A EP1230353A4 EP 1230353 A4 EP1230353 A4 EP 1230353A4 EP 20000980512 EP20000980512 EP 20000980512 EP 00980512 A EP00980512 A EP 00980512A EP 1230353 A4 EP1230353 A4 EP 1230353A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- protein
- disruption
- bifunctional molecules
- interactions
- protein interactions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16667599P | 1999-11-19 | 1999-11-19 | |
US166675P | 1999-11-19 | ||
PCT/US2000/031695 WO2001036612A1 (en) | 1999-11-19 | 2000-11-17 | Bifunctional molecules and their use in the disruption of protein-protein interactions |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1230353A1 EP1230353A1 (en) | 2002-08-14 |
EP1230353A4 true EP1230353A4 (en) | 2002-11-06 |
Family
ID=22604262
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20000980512 Withdrawn EP1230353A4 (en) | 1999-11-19 | 2000-11-17 | Bifunctional molecules and their use in the disruption of protein-protein interactions |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1230353A4 (en) |
AU (1) | AU1776501A (en) |
WO (1) | WO2001036612A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2044001A (en) | 1999-11-19 | 2001-05-30 | Board Of Trustees Of The Leland Stanford Junior University | Targeted bifunctional molecules and therapies based thereon |
US9428845B1 (en) | 2010-12-28 | 2016-08-30 | Warp Drive Bio, Inc. | Identifying new therapeutic agents |
WO2016112295A1 (en) | 2015-01-09 | 2016-07-14 | Warp Drive Bio, Inc. | Compounds that participate in cooperative binding and uses thereof |
WO2017059207A1 (en) | 2015-10-01 | 2017-04-06 | Warp Drive Bio, Inc. | Methods and reagents for analyzing protein-protein interfaces |
KR102615448B1 (en) | 2016-04-12 | 2023-12-19 | 징코 바이오웍스, 인크. | Compositions and methods for the production of compounds |
CA3042231A1 (en) | 2016-10-28 | 2018-05-03 | Ginkgo Bioworks, Inc. | Compositions and methods for the production of compounds |
WO2021091967A1 (en) | 2019-11-04 | 2021-05-14 | Revolution Medicines, Inc. | Ras inhibitors |
TW202132314A (en) | 2019-11-04 | 2021-09-01 | 美商銳新醫藥公司 | Ras inhibitors |
BR112022008565A2 (en) | 2019-11-04 | 2022-08-09 | Revolution Medicines Inc | COMPOUND, PHARMACEUTICAL COMPOSITION, CONJUGATE, METHODS TO TREAT CANCER AND A RAS PROTEIN-RELATED DISORDER |
MX2023003060A (en) | 2020-09-15 | 2023-04-05 | Revolution Medicines Inc | Indole derivatives as ras inhibitors in the treatment of cancer. |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999061055A1 (en) * | 1998-05-22 | 1999-12-02 | The Board Of Trustees Of The Leland Stanford Junior University | Bifunctional molecules and therapies based thereon |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1978095A1 (en) * | 1993-02-12 | 2008-10-08 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptor proteins for controlling signal transduction and ligands binding thereto |
-
2000
- 2000-11-17 WO PCT/US2000/031695 patent/WO2001036612A1/en not_active Application Discontinuation
- 2000-11-17 EP EP20000980512 patent/EP1230353A4/en not_active Withdrawn
- 2000-11-17 AU AU17765/01A patent/AU1776501A/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999061055A1 (en) * | 1998-05-22 | 1999-12-02 | The Board Of Trustees Of The Leland Stanford Junior University | Bifunctional molecules and therapies based thereon |
Non-Patent Citations (1)
Title |
---|
See also references of WO0136612A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP1230353A1 (en) | 2002-08-14 |
WO2001036612A1 (en) | 2001-05-25 |
AU1776501A (en) | 2001-05-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1084109A1 (en) | 2-,3-,4-,or 5-substituted-n1-(benzensulfonyl) indoles and their use in therapy 2- | |
AU2001293553A1 (en) | Phosphatidylserine-carrying apoptosis-mimicking bodies and the use thereof in medical treatment | |
IL205242A0 (en) | Substituted oxazolidinones and their use in the field of blood coagulation | |
GB9721437D0 (en) | Heteroaromatic compounds and their use in medicine | |
HK1039637A1 (en) | Heteroduplex mutational vectors and use thereof in bacteria | |
HU9902952D0 (en) | Water-soluble pharmaceutical copositions in an ionic complex and the use thereof | |
HUP0101137A3 (en) | Anticoagulant amidines and their pharmaceutical use | |
PT1212317E (en) | INDOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF OSTEOPOROSIS BETWEEN OTHER APPLICATIONS | |
AU4196801A (en) | Chordin-like-2 molecules and uses thereof | |
HUP0203896A3 (en) | Substituted 8-arylquinoline phosphodiesterase-4-inhibitors and use thereof | |
HUP0203811A3 (en) | Use of polymeric material in the treatment of hard surfaces | |
EP1230353A4 (en) | Bifunctional molecules and their use in the disruption of protein-protein interactions | |
EP1147213A4 (en) | Novel rgs-containing molecules and uses thereof | |
AU2841801A (en) | Triazolotriazinones and the use thereof | |
GB2352234B (en) | Improvements in and relating to portable disc holders | |
AU2001266229A1 (en) | Hcn polypeptides and polynucleotides and their use in therapy | |
GB2370233B (en) | Apparatus for use in behaviour modification and the like | |
IL142778A0 (en) | Therapeutic product and its use | |
PL363048A1 (en) | Azabicyclic derivatives and their therapeutic use | |
AU2001277119A1 (en) | Human kininogen d5 domain polypeptides and their use | |
FI964809A0 (en) | In the case of use of the processing unit | |
ZA981782B (en) | The use of levobupivacaine in combination with other drugs | |
GB2336582B (en) | Improvements in storage and display devices | |
AU3294700A (en) | Self-contained and mobile washstand for recurrent use in medical environment | |
EP1229924A4 (en) | Targeted bifunctional molecules and therapies based thereon |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020506 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
A4 | Supplementary search report drawn up and despatched | ||
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20021106 |
|
17Q | First examination report despatched |
Effective date: 20060524 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20070519 |