JP2020182453A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020182453A5 JP2020182453A5 JP2020076547A JP2020076547A JP2020182453A5 JP 2020182453 A5 JP2020182453 A5 JP 2020182453A5 JP 2020076547 A JP2020076547 A JP 2020076547A JP 2020076547 A JP2020076547 A JP 2020076547A JP 2020182453 A5 JP2020182453 A5 JP 2020182453A5
- Authority
- JP
- Japan
- Prior art keywords
- primer
- target
- nucleic acid
- acid sequence
- tail
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000007523 nucleic acids Chemical class 0.000 claims 44
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 27
- 238000000034 method Methods 0.000 claims 25
- 239000002773 nucleotide Substances 0.000 claims 25
- 125000003729 nucleotide group Chemical group 0.000 claims 25
- 238000012163 sequencing technique Methods 0.000 claims 21
- 108020004707 nucleic acids Proteins 0.000 claims 18
- 102000039446 nucleic acids Human genes 0.000 claims 18
- 239000000523 sample Substances 0.000 claims 14
- 238000009396 hybridization Methods 0.000 claims 8
- 108091093088 Amplicon Proteins 0.000 claims 6
- 230000001419 dependent effect Effects 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 108091034117 Oligonucleotide Proteins 0.000 claims 3
- 238000000137 annealing Methods 0.000 claims 3
- 239000012472 biological sample Substances 0.000 claims 3
- 230000008707 rearrangement Effects 0.000 claims 3
- 108020004414 DNA Proteins 0.000 claims 2
- 102100034343 Integrase Human genes 0.000 claims 1
- 108700020796 Oncogene Proteins 0.000 claims 1
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 239000002299 complementary DNA Substances 0.000 claims 1
- 239000011541 reaction mixture Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461931959P | 2014-01-27 | 2014-01-27 | |
| US61/931,959 | 2014-01-27 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016549249A Division JP7016215B2 (ja) | 2014-01-27 | 2015-01-26 | 配列決定のために核酸を調製する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020182453A JP2020182453A (ja) | 2020-11-12 |
| JP2020182453A5 true JP2020182453A5 (enExample) | 2021-02-25 |
Family
ID=53678460
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016549249A Active JP7016215B2 (ja) | 2014-01-27 | 2015-01-26 | 配列決定のために核酸を調製する方法 |
| JP2020076547A Pending JP2020182453A (ja) | 2014-01-27 | 2020-04-23 | 配列決定のために核酸を調製する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016549249A Active JP7016215B2 (ja) | 2014-01-27 | 2015-01-26 | 配列決定のために核酸を調製する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US10450597B2 (enExample) |
| EP (2) | EP4219744A3 (enExample) |
| JP (2) | JP7016215B2 (enExample) |
| AU (2) | AU2015209079B2 (enExample) |
| WO (1) | WO2015112974A1 (enExample) |
Families Citing this family (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US12655483B2 (en) | 2010-05-18 | 2026-06-16 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| EP2854058A3 (en) | 2010-05-18 | 2015-10-28 | Natera, Inc. | Methods for non-invasive pre-natal ploidy calling |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| AU2011348100B2 (en) | 2010-12-22 | 2016-08-25 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| JP6153874B2 (ja) | 2011-02-09 | 2017-06-28 | ナテラ， インコーポレイテッド | 非侵襲的出生前倍数性呼び出しのための方法 |
| EP3321378B1 (en) | 2012-02-27 | 2021-11-10 | Becton, Dickinson and Company | Compositions for molecular counting |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| CN105705659B (zh) | 2013-08-28 | 2019-11-29 | 贝克顿迪金森公司 | 大规模平行单细胞分析 |
| EP3105349B1 (en) | 2014-02-11 | 2020-07-15 | F. Hoffmann-La Roche AG | Targeted sequencing and uid filtering |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| RU2717641C2 (ru) | 2014-04-21 | 2020-03-24 | Натера, Инк. | Обнаружение мутаций и плоидности в хромосомных сегментах |
| US20180173845A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| WO2016138496A1 (en) | 2015-02-27 | 2016-09-01 | Cellular Research, Inc. | Spatially addressable molecular barcoding |
| EP3262189B1 (en) * | 2015-02-27 | 2021-12-08 | Becton, Dickinson and Company | Methods for barcoding nucleic acids for sequencing |
| CN107406888A (zh) | 2015-03-30 | 2017-11-28 | 赛卢拉研究公司 | 用于组合条形编码的方法和组合物 |
| EP3286326B1 (en) | 2015-04-23 | 2025-01-22 | Becton, Dickinson and Company | Method for whole transcriptome amplification |
| EP4428863A3 (en) | 2015-05-11 | 2024-12-11 | Natera, Inc. | Methods and compositions for determining ploidy |
| CN107922970B (zh) | 2015-08-06 | 2021-09-28 | 豪夫迈·罗氏有限公司 | 通过单探针引物延伸的靶标富集 |
| WO2017044574A1 (en) | 2015-09-11 | 2017-03-16 | Cellular Research, Inc. | Methods and compositions for nucleic acid library normalization |
| ES2893000T3 (es) * | 2015-12-01 | 2022-02-07 | Seracare Life Sciences Inc | Materiales de referencia celulares multiplex |
| JP7280044B2 (ja) | 2016-04-15 | 2023-05-23 | ナテラ， インコーポレイテッド | 肺癌の検出方法 |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| WO2017210469A2 (en) | 2016-06-01 | 2017-12-07 | F. Hoffman-La Roche Ag | Immuno-pete |
| ES2855748T3 (es) * | 2016-07-12 | 2021-09-24 | Hoffmann La Roche | Enriquecimiento de diana de extensión de cebador |
| CA3037190A1 (en) | 2016-09-15 | 2018-03-22 | ArcherDX, Inc. | Methods of nucleic acid sample preparation for analysis of cell-free dna |
| US12630864B2 (en) | 2016-09-15 | 2026-05-19 | Laboratory Corporation Of America Holdings | Methods of nucleic acid sample preparation |
| CN109937254B (zh) | 2016-09-15 | 2023-05-30 | 阿谢尔德克斯有限责任公司 | 核酸样品制备方法 |
| IL265478B2 (en) | 2016-09-26 | 2024-10-01 | Becton Dickinson Co | Measurement of protein expression using reagents with barcoded oligonucleotide sequences |
| WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| CN110312825A (zh) | 2016-10-24 | 2019-10-08 | 吉内恩福赛克公司 | 隐藏核酸内存在的信息 |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| CA3042391A1 (en) * | 2016-11-02 | 2018-05-11 | ArcherDX, Inc. | Methods of nucleic acid sample preparation for immune repertoire sequencing |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| CN106755451A (zh) * | 2017-01-05 | 2017-05-31 | 苏州艾达康医疗科技有限公司 | 核酸制备及分析 |
| US11319583B2 (en) | 2017-02-01 | 2022-05-03 | Becton, Dickinson And Company | Selective amplification using blocking oligonucleotides |
| US12297491B2 (en) | 2017-03-08 | 2025-05-13 | Roche Sequencing Solutions, Inc. | Primer extension target enrichment and improvements thereto including simultaneous enrichment of DNA and RNA |
| JP6970205B2 (ja) | 2017-03-08 | 2021-11-24 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Ｄｎａおよびｒｎａの同時濃縮を含むプライマー伸長標的濃縮およびそれに対する向上 |
| JP7536450B2 (ja) | 2017-06-05 | 2024-08-20 | ベクトン・ディキンソン・アンド・カンパニー | 単一細胞用のサンプルインデックス付加 |
| US11505826B2 (en) | 2017-07-12 | 2022-11-22 | Agilent Technologies, Inc. | Sequencing method for genomic rearrangement detection |
| WO2019118926A1 (en) | 2017-12-14 | 2019-06-20 | Tai Diagnostics, Inc. | Assessing graft suitability for transplantation |
| EP4269582A3 (en) * | 2017-12-21 | 2024-01-24 | F. Hoffmann-La Roche AG | Target enrichment by unidirectional dual probe primer extension |
| EP3737773B1 (en) | 2018-01-12 | 2023-04-12 | Natera, Inc. | Novel primers and uses thereof |
| DK3781714T3 (da) | 2018-04-14 | 2026-03-30 | Natera Inc | Fremgangsmåder til cancerpåvisning og -overvågning ved personlig påvisning af cirkulerende tumor-dna |
| EP3788170B1 (en) | 2018-05-03 | 2025-01-01 | Becton, Dickinson and Company | Molecular barcoding on opposite transcript ends |
| CA3097976A1 (en) | 2018-05-03 | 2019-11-07 | Becton, Dickinson And Company | High throughput multiomics sample analysis |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| EP3861134B1 (en) | 2018-10-01 | 2024-09-04 | Becton, Dickinson and Company | Determining 5' transcript sequences |
| EP3877520B1 (en) | 2018-11-08 | 2025-03-19 | Becton, Dickson And Company | Whole transcriptome analysis of single cells using random priming |
| EP3887385B1 (en) | 2018-11-30 | 2024-03-20 | Geneinfosec, Inc. | A method for generating random oligonucleotides and determining their sequence |
| EP3894552B1 (en) | 2018-12-13 | 2026-01-28 | Becton, Dickinson and Company | Selective extension in single cell whole transcriptome analysis |
| EP3914728B1 (en) | 2019-01-23 | 2023-04-05 | Becton, Dickinson and Company | Oligonucleotides associated with antibodies |
| CN113454234B (zh) | 2019-02-14 | 2025-03-18 | 贝克顿迪金森公司 | 杂合体靶向和全转录物组扩增 |
| US12305235B2 (en) | 2019-06-06 | 2025-05-20 | Natera, Inc. | Methods for detecting immune cell DNA and monitoring immune system |
| WO2021016239A1 (en) | 2019-07-22 | 2021-01-28 | Becton, Dickinson And Company | Single cell chromatin immunoprecipitation sequencing assay |
| EP4055160B1 (en) | 2019-11-08 | 2024-04-10 | Becton Dickinson and Company | Using random priming to obtain full-length v(d)j information for immune repertoire sequencing |
| CN115279919A (zh) | 2020-01-13 | 2022-11-01 | 贝克顿迪金森公司 | 使用含有du的寡核苷酸的细胞捕获 |
| CN115244184A (zh) | 2020-01-13 | 2022-10-25 | 贝克顿迪金森公司 | 用于定量蛋白和rna的方法和组合物 |
| WO2021155057A1 (en) | 2020-01-29 | 2021-08-05 | Becton, Dickinson And Company | Barcoded wells for spatial mapping of single cells through sequencing |
| US12153043B2 (en) | 2020-02-25 | 2024-11-26 | Becton, Dickinson And Company | Bi-specific probes to enable the use of single-cell samples as single color compensation control |
| WO2021231779A1 (en) | 2020-05-14 | 2021-11-18 | Becton, Dickinson And Company | Primers for immune repertoire profiling |
| CN115803445A (zh) | 2020-06-02 | 2023-03-14 | 贝克顿迪金森公司 | 用于5撇基因表达测定的寡核苷酸和珠 |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| WO2022026909A1 (en) | 2020-07-31 | 2022-02-03 | Becton, Dickinson And Company | Single cell assay for transposase-accessible chromatin |
| JP2023547732A (ja) * | 2020-11-03 | 2023-11-13 | エイシーティ・ジェノミックス（アイピー）リミテッド | 遺伝子改変を検出するための標的化シークエンシング方法およびそのキット |
| WO2022109343A1 (en) | 2020-11-20 | 2022-05-27 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
| CN116685850A (zh) | 2020-12-15 | 2023-09-01 | 贝克顿迪金森公司 | 单细胞分泌组分析 |
| EP4448793A4 (en) * | 2021-12-14 | 2025-12-17 | Univ Arizona State | METHOD FOR COMBINATION OF IN-SITU SINGLE-CELL DNA AND RNA SEQUENCEMENT |
Family Cites Families (107)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4868104A (en) | 1985-09-06 | 1989-09-19 | Syntex (U.S.A.) Inc. | Homogeneous assay for specific polynucleotides |
| US6027913A (en) | 1988-01-28 | 2000-02-22 | Sommer; Steven S. | Nucleic acid amplification with direct sequencing |
| GB8818020D0 (en) | 1988-07-28 | 1988-09-01 | Ici Plc | Method for amplification of nucleotide sequences |
| US6087101A (en) | 1990-05-18 | 2000-07-11 | Gruelich; Karl Otto | Optical characterization of nucleic acids and oligonucleotides |
| US5846719A (en) | 1994-10-13 | 1998-12-08 | Lynx Therapeutics, Inc. | Oligonucleotide tags for sorting and identification |
| US5565340A (en) | 1995-01-27 | 1996-10-15 | Clontech Laboratories, Inc. | Method for suppressing DNA fragment amplification during PCR |
| WO1997023646A1 (en) | 1995-12-22 | 1997-07-03 | Behringwerke Aktiengesellschaft | Detection of differences in nucleic acids |
| CA2239683A1 (en) | 1995-12-22 | 1997-07-03 | Dade Behring Marburg Gmbh | Homogeneous amplification and detection of nucleic acids |
| US5827658A (en) | 1996-08-09 | 1998-10-27 | The United States Of America As Reprsented By The Department Of Health And Human Services | Isolation of amplified genes via cDNA subtractive hybridization |
| US6482590B1 (en) | 1996-12-20 | 2002-11-19 | Aventis Behring Gmbh | Method for polynucleotide amplification |
| US6365346B1 (en) | 1998-02-18 | 2002-04-02 | Dade Behring Inc. | Quantitative determination of nucleic acid amplification products |
| US6235502B1 (en) | 1998-09-18 | 2001-05-22 | Molecular Staging Inc. | Methods for selectively isolating DNA using rolling circle amplification |
| US6200757B1 (en) | 1999-01-19 | 2001-03-13 | Dade Behring Inc. | Method for controlling the extension of an oligonucleotide |
| WO2000043543A1 (en) | 1999-01-19 | 2000-07-27 | Dade Behring Inc. | Detection of differences between polynucleotides |
| WO2000070095A2 (en) | 1999-05-17 | 2000-11-23 | Dade Behring Inc. | Homogeneous isothermal amplification and detection of nucleic acids using a template switch oligonucleotide |
| US6818395B1 (en) | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
| US6232104B1 (en) | 1999-08-17 | 2001-05-15 | Dade Behring Inc. | Detection of differences in nucleic acids by inhibition of spontaneous DNA branch migration |
| ATE262595T1 (de) | 1999-09-13 | 2004-04-15 | Nugen Technologies Inc | Methoden und zusammensetzungen zur linearen isothermalen amplifikation von polynukleotidsequenzen |
| US7244559B2 (en) | 1999-09-16 | 2007-07-17 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| WO2001023610A2 (en) | 1999-09-29 | 2001-04-05 | Solexa Ltd. | Polynucleotide sequencing |
| US6309836B1 (en) | 1999-10-05 | 2001-10-30 | Marek Kwiatkowski | Compounds for protecting hydroxyls and methods for their use |
| AU5741101A (en) | 2000-04-28 | 2001-11-12 | Digital Gene Technologies, Inc. | Methods for rapid isolation and sequence determination of gene-specific sequences |
| EP1356094B1 (en) | 2000-06-26 | 2010-01-13 | Nugen Technologies, Inc. | Methods and compositions for transcription-based nucleic acid amplification |
| EP1176212A1 (en) | 2000-07-24 | 2002-01-30 | Centre National de Genotype | Method for haplotyping by mass spectrometry |
| AU2002213096B2 (en) | 2000-10-06 | 2007-03-29 | Nugen Technologies, Inc. | Methods and probes for detection and/or quantification of nucleic acid sequences |
| JP2002153271A (ja) * | 2000-11-17 | 2002-05-28 | Jeol Ltd | Ｄｎａあるいはｒｎａの塩基配列決定方法およびｄｎａシーケンサー |
| EP1427847B1 (en) | 2000-12-13 | 2010-07-28 | Nugen Technologies, Inc. | Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof |
| AU2005203617A1 (en) * | 2001-03-09 | 2005-09-01 | Nugen Technologies, Inc | Methods and compositions for amplification of RNA sequences |
| MXPA02012739A (es) | 2001-03-09 | 2004-04-20 | Nugen Technologies Inc | Metodos y composiciones para amplificacion de secuencias de arn. |
| US6632611B2 (en) | 2001-07-20 | 2003-10-14 | Affymetrix, Inc. | Method of target enrichment and amplification |
| US20030104432A1 (en) | 2001-07-27 | 2003-06-05 | The Regents Of The University Of California | Methods of amplifying sense strand RNA |
| WO2003078645A2 (en) | 2002-03-11 | 2003-09-25 | Nugen Technologies, Inc. | Methods for generating double stranded dna comprising a 3’ single stranded portion and uses of these complexes for recombination |
| EP1490514A4 (en) | 2002-03-29 | 2008-12-17 | Nugen Technologies Inc | THROUGH ISOTHERME SINGLE PRIMER NUCLEIC ACID AMPLIFICATION IMPROVED DETECTION AND QUANTIFICATION OF ANALYTES |
| WO2004011665A2 (en) | 2002-05-17 | 2004-02-05 | Nugen Technologies, Inc. | Methods for fragmentation, labeling and immobilization of nucleic acids |
| US7273730B2 (en) | 2002-05-24 | 2007-09-25 | Invitrogen Corporation | Nested PCR employing degradable primers |
| US7459273B2 (en) | 2002-10-04 | 2008-12-02 | Affymetrix, Inc. | Methods for genotyping selected polymorphism |
| DE602004026033D1 (de) | 2003-01-29 | 2010-04-29 | 454 Corp | Zweiendige sequenzierung |
| EP1454992B1 (en) | 2003-03-07 | 2006-05-31 | Istituto Nazionale Per Lo Studio E La Cura Dei Tumori | Anaplastic lymphoma kinase assay, reagents and compositions thereof |
| JP2006523465A (ja) | 2003-04-14 | 2006-10-19 | ニューゲン テクノロジーズ， インコーポレイテッド | ランダムにプライミングされる複合プライマーを用いる大規模増幅 |
| US7226720B2 (en) | 2003-09-08 | 2007-06-05 | General Electric Company | Limited play data storage media and method for limiting access to data thereon |
| US7824856B2 (en) | 2003-09-10 | 2010-11-02 | Althea Technologies, Inc. | Expression profiling using microarrays |
| WO2005045073A1 (en) * | 2003-11-10 | 2005-05-19 | Seegene, Inc. | Method for amplifying unknown dna sequence adjacent to known sequence |
| US7169560B2 (en) | 2003-11-12 | 2007-01-30 | Helicos Biosciences Corporation | Short cycle methods for sequencing polynucleotides |
| JP5138938B2 (ja) | 2003-12-19 | 2013-02-06 | プレキシコン インコーポレーテッド | Ｒｅｔ調節剤の開発のための化合物および方法 |
| CA2552007A1 (en) | 2003-12-29 | 2005-07-21 | Nugen Technologies, Inc. | Methods for analysis of nucleic acid methylation status and methods for fragmentation, labeling and immobilization of nucleic acids |
| JP3972106B2 (ja) | 2004-03-03 | 2007-09-05 | 大学共同利用機関法人情報・システム研究機構 | ゲノムライブラリー作製方法、および同方法により作製されたゲノムライブラリー |
| GB0421525D0 (en) | 2004-09-28 | 2004-10-27 | Novartis Ag | Inhibitors of protein kineses |
| US20070070349A1 (en) | 2005-09-23 | 2007-03-29 | Helicos Biosciences Corporation | Optical train and method for TIRF single molecule detection and analysis |
| US7220549B2 (en) | 2004-12-30 | 2007-05-22 | Helicos Biosciences Corporation | Stabilizing a nucleic acid for nucleic acid sequencing |
| EP1929046B1 (en) | 2005-09-07 | 2012-07-11 | Nugen Technologies, Inc. | Improved nucleic acid amplification procedure |
| GB0522310D0 (en) | 2005-11-01 | 2005-12-07 | Solexa Ltd | Methods of preparing libraries of template polynucleotides |
| EP1957667A1 (en) | 2005-11-15 | 2008-08-20 | Solexa Ltd. | Method of target enrichment |
| US7282337B1 (en) | 2006-04-14 | 2007-10-16 | Helicos Biosciences Corporation | Methods for increasing accuracy of nucleic acid sequencing |
| US8192940B2 (en) | 2006-05-04 | 2012-06-05 | Seegene, Inc. | Method for amplifying unknown DNA sequence adjacent to known sequence |
| US20090275486A1 (en) | 2006-05-16 | 2009-11-05 | Nurith Kurn | Nucleic acid separation and purification method based on reversible charge interactions |
| WO2008005459A2 (en) | 2006-06-30 | 2008-01-10 | Nugen Technologies, Inc. | Methods for fragmentation and labeling of nucleic acids |
| EP2677309B9 (en) | 2006-12-14 | 2014-11-19 | Life Technologies Corporation | Methods for sequencing a nucleic acid using large scale FET arrays, configured to measure a limited pH range |
| EP2121983A2 (en) | 2007-02-02 | 2009-11-25 | Illumina Cambridge Limited | Methods for indexing samples and sequencing multiple nucleotide templates |
| US8716190B2 (en) | 2007-09-14 | 2014-05-06 | Affymetrix, Inc. | Amplification and analysis of selected targets on solid supports |
| US20100248310A1 (en) | 2007-10-22 | 2010-09-30 | Monoquant Pty Ltd. | Method of dna amplification |
| EP2247727A4 (en) | 2008-02-12 | 2011-08-03 | Nugen Technologies Inc | PROCESS FOR ARCHIVING AND CLONING EXPANSION |
| US8034568B2 (en) * | 2008-02-12 | 2011-10-11 | Nugen Technologies, Inc. | Isothermal nucleic acid amplification methods and compositions |
| US7846666B2 (en) | 2008-03-21 | 2010-12-07 | Nugen Technologies, Inc. | Methods of RNA amplification in the presence of DNA |
| WO2009133466A2 (en) | 2008-04-30 | 2009-11-05 | Population Genetics Technologies Ltd. | Asymmetric adapter library construction |
| US20110172105A1 (en) | 2008-06-04 | 2011-07-14 | Salk Institute For Biological Studies | GREPSEQ: An Almost Inexhaustible, Cost-Effective, High-Throughput Protocol for the Generation of Selector Sequences |
| EP2313091A4 (en) | 2008-07-14 | 2012-04-04 | Univ Kingston | PHARMACEUTICAL COMPOSITIONS WITH RET-HEMMERN AND METHOD FOR THE TREATMENT OF CANCER |
| WO2010077288A2 (en) | 2008-12-09 | 2010-07-08 | The Salk Institute For Biological Studies | Methods for identifying differences in alternative splicing between two rna samples |
| WO2010083046A2 (en) | 2009-01-15 | 2010-07-22 | The Salk Institute For Biological Studies | Methods for using next generation sequencing to identify 5-methyl cytosines in the genome |
| US20100286143A1 (en) * | 2009-04-24 | 2010-11-11 | Dora Dias-Santagata | Methods and materials for genetic analysis of tumors |
| EP2464738A4 (en) | 2009-08-12 | 2013-05-01 | Nugen Technologies Inc | METHODS, COMPOSITIONS, AND KITS FOR GENERATING NUCLEIC ACID PRODUCTS SUBSTANTIALLY FREE OF MATRIX NUCLEIC ACID |
| WO2011032053A1 (en) | 2009-09-11 | 2011-03-17 | Nugen Technologies, Inc. | Compositions and methods for whole transcriptome analysis |
| GB2487341A (en) | 2009-11-02 | 2012-07-18 | Nugen Technologies Inc | Compositions and methods for targeted nucleic acid sequence selection and amplification |
| WO2011056866A2 (en) | 2009-11-05 | 2011-05-12 | Epicentre Technologies Corporation | Methods and kits for 3'-end-tagging of rna |
| US20110269647A1 (en) | 2010-04-28 | 2011-11-03 | Medical Research Council | Method |
| EP2854058A3 (en) | 2010-05-18 | 2015-10-28 | Natera, Inc. | Methods for non-invasive pre-natal ploidy calling |
| WO2011156529A2 (en) | 2010-06-08 | 2011-12-15 | Nugen Technologies, Inc. | Methods and composition for multiplex sequencing |
| WO2012003374A2 (en) | 2010-07-02 | 2012-01-05 | The Board Of Trustees Of The Leland Stanford Junior University | Targeted sequencing library preparation by genomic dna circularization |
| EP2619327B1 (en) | 2010-09-21 | 2014-10-22 | Population Genetics Technologies LTD. | Increasing confidence of allele calls with molecular counting |
| AU2011305445B2 (en) | 2010-09-24 | 2017-03-16 | The Board Of Trustees Of The Leland Stanford Junior University | Direct capture, amplification and sequencing of target DNA using immobilized primers |
| US20120100549A1 (en) | 2010-10-01 | 2012-04-26 | Ibis Biosciences, Inc. | Targeted genome amplification methods |
| DK2630263T4 (da) | 2010-10-22 | 2022-02-14 | Cold Spring Harbor Laboratory | Varital tælling af nucleinsyrer for at opnå information om antal genomiske kopier |
| WO2012064739A2 (en) * | 2010-11-08 | 2012-05-18 | The Trustees Of Columbia University In The City Of New York | Microbial enrichment primers |
| AU2011348100B2 (en) | 2010-12-22 | 2016-08-25 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| WO2012103154A1 (en) | 2011-01-24 | 2012-08-02 | Nugen Technologies, Inc. | Stem-loop composite rna-dna adaptor-primers: compositions and methods for library generation, amplification and other downstream manipulations |
| JP6153874B2 (ja) | 2011-02-09 | 2017-06-28 | ナテラ， インコーポレイテッド | 非侵襲的出生前倍数性呼び出しのための方法 |
| WO2012112804A1 (en) | 2011-02-18 | 2012-08-23 | Raindance Technoligies, Inc. | Compositions and methods for molecular labeling |
| WO2012131616A1 (en) * | 2011-03-30 | 2012-10-04 | Chromous Biotech Pvt. Ltd. | Primer set, kit and methods thereof |
| EP3246416B1 (en) | 2011-04-15 | 2024-06-05 | The Johns Hopkins University | Safe sequencing system |
| SG10201605049QA (en) * | 2011-05-20 | 2016-07-28 | Fluidigm Corp | Nucleic acid encoding reactions |
| CN103890191B (zh) | 2011-05-27 | 2018-12-04 | 哈佛大学校长及研究员协会 | 单细胞全基因组扩增方法 |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| EP2769007B1 (en) | 2011-10-19 | 2016-12-07 | Nugen Technologies, Inc. | Compositions and methods for directional nucleic acid amplification and sequencing |
| WO2013074833A1 (en) | 2011-11-16 | 2013-05-23 | The Board Of Trustees Of The Leland Stanford Junior University | Capture probe and assay for analysis of fragmented nucleic acids |
| CN105861487B (zh) | 2012-01-26 | 2020-05-05 | 纽亘技术公司 | 用于靶向核酸序列富集和高效文库产生的组合物和方法 |
| WO2013122826A1 (en) | 2012-02-14 | 2013-08-22 | Gnubio, Inc. | Cascaded addition of target specific universal adapters to nucleic acids |
| SMT202100154T1 (it) | 2012-02-17 | 2021-05-07 | Hutchinson Fred Cancer Res | Composizioni e metodi per identificare precisamente mutazioni |
| EP4026912A1 (en) * | 2012-05-10 | 2022-07-13 | The General Hospital Corporation | Methods for determining a nucleotide sequence |
| CA2877094A1 (en) | 2012-06-18 | 2013-12-27 | Nugen Technologies, Inc. | Compositions and methods for negative selection of non-desired nucleic acid sequences |
| US20150011396A1 (en) | 2012-07-09 | 2015-01-08 | Benjamin G. Schroeder | Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing |
| WO2014047678A1 (en) | 2012-09-25 | 2014-04-03 | Agriculture Victoria Services Pty Ltd | Method of producing a normalised nucleic acid library using solid state capture material |
| EP2971130A4 (en) | 2013-03-15 | 2016-10-05 | Nugen Technologies Inc | SEQUENTIAL SEQUENCING |
| US20140274729A1 (en) | 2013-03-15 | 2014-09-18 | Nugen Technologies, Inc. | Methods, compositions and kits for generation of stranded rna or dna libraries |
| JP6525473B2 (ja) | 2013-11-13 | 2019-06-05 | ニューゲン テクノロジーズ， インコーポレイテッド | 複製物配列決定リードを同定するための組成物および方法 |
| US9689027B2 (en) | 2013-11-15 | 2017-06-27 | The Board Of Trustees Of The Leland Stanford Junior University | High efficiency multiplexed nucleic acid capture in a structured microenvironment |
| CA3037190A1 (en) | 2016-09-15 | 2018-03-22 | ArcherDX, Inc. | Methods of nucleic acid sample preparation for analysis of cell-free dna |
| CN109937254B (zh) | 2016-09-15 | 2023-05-30 | 阿谢尔德克斯有限责任公司 | 核酸样品制备方法 |
| CA3042391A1 (en) | 2016-11-02 | 2018-05-11 | ArcherDX, Inc. | Methods of nucleic acid sample preparation for immune repertoire sequencing |
-
2015
- 2015-01-26 AU AU2015209079A patent/AU2015209079B2/en active Active
- 2015-01-26 EP EP23152512.2A patent/EP4219744A3/en active Pending
- 2015-01-26 US US14/605,363 patent/US10450597B2/en active Active
- 2015-01-26 WO PCT/US2015/012891 patent/WO2015112974A1/en not_active Ceased
- 2015-01-26 EP EP15740988.9A patent/EP3099820A4/en not_active Ceased
- 2015-01-26 JP JP2016549249A patent/JP7016215B2/ja active Active
-
2019
- 2019-10-02 US US16/590,878 patent/US11807897B2/en active Active
-
2020
- 2020-04-23 JP JP2020076547A patent/JP2020182453A/ja active Pending
-
2021
- 2021-10-08 AU AU2021245236A patent/AU2021245236B2/en active Active
-
2023
- 2023-10-04 US US18/481,021 patent/US12371732B2/en active Active
-
2025
- 2025-06-27 US US19/252,627 patent/US20250376715A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR100977186B1 (ko) | 이중 특이성 올리고뉴클레오타이드를 사용한 방법 및 이중특이성 올리고뉴클레오타이드 | |
| KR101243266B1 (ko) | 이중 특이성 올리고뉴클레오타이드를 사용한 방법 및 이중 특이성 올리고뉴클레오타이드 | |
| US9057110B2 (en) | Method for direct amplification from crude nucleic acid samples | |
| JP2024114703A5 (enExample) | ||
| US20100273159A1 (en) | Nested Multiplex Amplification Method for Identification of Multiple Biological Entities | |
| JP2011500092A5 (enExample) | ||
| CA2468754A1 (en) | Annealing control primer and its uses | |
| JP2020516281A5 (enExample) | ||
| CA2476564A1 (en) | Polynomial amplification of nucleic acids | |
| JP2021094038A (ja) | 核酸を調製するための等温方法および関連組成物 | |
| US20200232011A1 (en) | Methods of nucleic acid detection and primer design | |
| JP7539770B2 (ja) | ゲノム再編成検出のための配列決定方法 | |
| JP2021503903A (ja) | 非対称ｐｃｒ法 | |
| JP6847364B2 (ja) | オリゴカチオン複合プライマー配列を使用する等温増幅 | |
| US10801056B2 (en) | Kit and method for detection of microRNA | |
| JP2022512264A5 (enExample) | ||
| JP2009513142A5 (enExample) | ||
| WO2017183648A1 (ja) | 多項目増幅手法 | |
| US7501254B2 (en) | Methods and compositions for amplification and capture of nucleic acid sequences | |
| WO2012032510A1 (en) | Primers for amplifying dna and methods of selecting same | |
| CN109415762B (zh) | 通过多重扩增双重信号扩增的目标核酸序列的检测方法 | |
| JP6983906B2 (ja) | ライブラリーの定量および定性 | |
| JP2022553164A5 (enExample) | ||
| CN111334562A (zh) | 一种含有修饰引物的核酸扩增方法和试剂盒 | |
| JP2024002889A (ja) | Ｄｎａライブラリーの作製キット及び作製方法、遺伝子多型の検出方法 |