|
US1016745A
(en)
|
1911-04-11 |
1912-02-06 |
Edwin C Henrikson |
Table-caster.
|
|
US5139941A
(en)
|
1985-10-31 |
1992-08-18 |
University Of Florida Research Foundation, Inc. |
AAV transduction vectors
|
|
US5436146A
(en)
|
1989-09-07 |
1995-07-25 |
The Trustees Of Princeton University |
Helper-free stocks of recombinant adeno-associated virus vectors
|
|
US6268213B1
(en)
|
1992-06-03 |
2001-07-31 |
Richard Jude Samulski |
Adeno-associated virus vector and cis-acting regulatory and promoter elements capable of expressing at least one gene and method of using same for gene therapy
|
|
US5869305A
(en)
|
1992-12-04 |
1999-02-09 |
The University Of Pittsburgh |
Recombinant viral vector system
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US5856152A
(en)
|
1994-10-28 |
1999-01-05 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV vector and methods of use therefor
|
|
US5652224A
(en)
|
1995-02-24 |
1997-07-29 |
The Trustees Of The University Of Pennsylvania |
Methods and compositions for gene therapy for the treatment of defects in lipoprotein metabolism
|
|
US6093570A
(en)
|
1995-06-07 |
2000-07-25 |
The University Of North Carolina At Chapel Hill |
Helper virus-free AAV production
|
|
US5741683A
(en)
|
1995-06-07 |
1998-04-21 |
The Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
|
JP2001500497A
(ja)
|
1996-09-06 |
2001-01-16 |
トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスに指図される遺伝子治療の方法
|
|
US5866552A
(en)
|
1996-09-06 |
1999-02-02 |
The Trustees Of The University Of Pennsylvania |
Method for expressing a gene in the absence of an immune response
|
|
US20020037867A1
(en)
|
1999-02-26 |
2002-03-28 |
James M. Wilson |
Method for recombinant adeno-associated virus-directed gene therapy
|
|
AU722375B2
(en)
|
1996-09-06 |
2000-08-03 |
Trustees Of The University Of Pennsylvania, The |
Methods using cre-lox for production of recombinant adeno-associated viruses
|
|
EP0931158A1
(en)
|
1996-09-06 |
1999-07-28 |
The Trustees Of The University Of Pennsylvania |
An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase
|
|
WO1998011244A2
(en)
|
1996-09-11 |
1998-03-19 |
The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Aav4 vector and uses thereof
|
|
ES2215222T3
(es)
|
1996-12-05 |
2004-10-01 |
Crucell Holland B.V. |
Modificacion genetica de celulas cepa de repoblacion hematopoyeticas de primates.
|
|
JP2002503954A
(ja)
|
1997-04-01 |
2002-02-05 |
グラクソ、グループ、リミテッド |
核酸増幅法
|
|
US6548286B1
(en)
|
1997-04-14 |
2003-04-15 |
Cell Genesys, Inc. |
Methods for increasing the efficiency of recombinant AAV product
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
US6251677B1
(en)
|
1997-08-25 |
2001-06-26 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV virus and methods of use thereof
|
|
WO1999014354A1
(en)
|
1997-09-19 |
1999-03-25 |
The Trustees Of The University Of The Pennsylvania |
Methods and vector constructs useful for production of recombinant aav
|
|
EP1015619A1
(en)
|
1997-09-19 |
2000-07-05 |
The Trustees Of The University Of Pennsylvania |
Methods and cell line useful for production of recombinant adeno-associated viruses
|
|
CA2304131A1
(en)
|
1997-09-19 |
1999-04-01 |
James M. Wilson |
Method for gene transfer using bcl2 and compositions useful therein
|
|
EP1064393B1
(en)
|
1998-03-20 |
2004-12-29 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
US6953690B1
(en)
|
1998-03-20 |
2005-10-11 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
US6146874A
(en)
|
1998-05-27 |
2000-11-14 |
University Of Florida |
Method of preparing recombinant adeno-associated virus compositions
|
|
WO1999061601A2
(en)
|
1998-05-28 |
1999-12-02 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Aav5 vector and uses thereof
|
|
ATE362542T1
(de)
|
1998-11-05 |
2007-06-15 |
Univ Pennsylvania |
Nukleinsäuresequenzen des adeno-assoziierten virus des serotyps i, und vektoren und wirtszellen, die diese enthalten
|
|
US6759237B1
(en)
|
1998-11-05 |
2004-07-06 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
|
|
AU780231B2
(en)
|
1998-11-10 |
2005-03-10 |
University Of North Carolina At Chapel Hill, The |
Virus vectors and methods of making and administering the same
|
|
US6387368B1
(en)
|
1999-02-08 |
2002-05-14 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV virus and methods of use thereof
|
|
US6258595B1
(en)
|
1999-03-18 |
2001-07-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
JP4693244B2
(ja)
|
1999-03-18 |
2011-06-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスのヘルパー無しの生産のための組成物および方法
|
|
CA2375098A1
(en)
|
1999-06-02 |
2000-12-14 |
Trustees Of The University Of Pennsylvania |
Compositions and methods useful for production of recombinant viruses which require helper viruses
|
|
CA2379166C
(en)
|
1999-08-09 |
2013-03-26 |
Targeted Genetics Corporation |
Enhancement of expression of a single-stranded, heterologous nucleotide sequence from recombinant viral vectors by designing the sequence such that it forms instrastrand base pairs
|
|
US6365394B1
(en)
|
1999-09-29 |
2002-04-02 |
The Trustees Of The University Of Pennsylvania |
Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus
|
|
JP2003523320A
(ja)
|
1999-09-29 |
2003-08-05 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
ウイルスベクターの迅速なｐｅｇ改変方法、高められた遺伝子形質導入のための組成物、高められた物理的安定性を伴う組成物、およびそのための用途
|
|
US7115391B1
(en)
|
1999-10-01 |
2006-10-03 |
Genovo, Inc. |
Production of recombinant AAV using adenovirus comprising AAV rep/cap genes
|
|
CA2385823A1
(en)
|
1999-10-01 |
2001-04-12 |
Haifeng Chen |
Production of recombinant aav using adenovirus comprising aav rep/cap genes
|
|
US6821512B1
(en)
|
1999-12-03 |
2004-11-23 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for increasing packaging and yield of recombinant adenoviruses using multiple packaging signals
|
|
CA2392537A1
(en)
|
1999-12-03 |
2001-06-07 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for increasing packaging and yields of recombinant adenoviruses using multiple packaging signals
|
|
US6855314B1
(en)
|
2000-03-22 |
2005-02-15 |
The United States Of America As Represented By The Department Of Health And Human Services |
AAV5 vector for transducing brain cells and lung cells
|
|
US6468524B1
(en)
|
2000-03-22 |
2002-10-22 |
The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
AAV4 vector and uses thereof
|
|
US7056502B2
(en)
|
2000-04-28 |
2006-06-06 |
The Trustees Of The University Of Pennsylvania |
Recombinant aav vectors with AAV5 capsids and AAV5 vectors pseudotyped in heterologous capsids
|
|
US20060057553A1
(en)
*
|
2000-05-30 |
2006-03-16 |
Estuardo Aguilar-Cordova |
Chimeric viral vectors for gene therapy
|
|
US7201898B2
(en)
|
2000-06-01 |
2007-04-10 |
The University Of North Carolina At Chapel Hill |
Methods and compounds for controlled release of recombinant parvovirus vectors
|
|
WO2002018659A2
(en)
|
2000-08-30 |
2002-03-07 |
Haplogen, Llc |
Method for determining alleles
|
|
CA2447240C
(en)
|
2001-05-18 |
2013-02-19 |
Wisconsin Alumni Research Foundation |
Method for the synthesis of dna sequences
|
|
AU2002324700A1
(en)
|
2001-08-14 |
2003-03-03 |
Bayer Ag |
Nucleic acid and amino acid sequences involved in pain
|
|
EP1442125A4
(en)
*
|
2001-10-04 |
2004-12-08 |
Carlos Estuard Aguilar-Cordova |
CHIMERAL VIRUS VECTORS FOR GENE THERAPY
|
|
MX359371B
(es)
|
2001-11-13 |
2018-09-25 |
Univ Pennsylvania |
Un metodo para detectar y/o identificar secuencias del virus adeno-asociado y aislamiento de secuencias novedosas identificadas de ese modo.
|
|
DK2573170T3
(en)
|
2001-12-17 |
2018-04-09 |
Univ Pennsylvania |
Sequences of adeno-associated virus (AAV) serotype 9, vectors containing them, and their use
|
|
PT1453547T
(pt)
|
2001-12-17 |
2016-12-28 |
Univ Pennsylvania |
Sequências do vírus adeno-associado (aav) do serotipo 8, vetores contendo as mesmas, e utilizações destas
|
|
AU2002367943A1
(en)
|
2001-12-18 |
2003-12-22 |
University Of North Carolina At Chapel Hill |
Improved reagents and methods for producing parvoviruses
|
|
AU2003274397A1
(en)
|
2002-06-05 |
2003-12-22 |
University Of Florida |
Production of pseudotyped recombinant aav virions
|
|
EP2345731B1
(en)
|
2003-09-30 |
2015-10-21 |
The Trustees of the University of Pennsylvania |
Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof
|
|
ES2525067T3
(es)
|
2005-04-07 |
2014-12-17 |
The Trustees Of The University Of Pennsylvania |
Método de incremento de la función de un vector de AAV
|
|
JP4495210B2
(ja)
|
2005-06-09 |
2010-06-30 |
パナソニック株式会社 |
振幅誤差補償装置及び直交度誤差補償装置
|
|
US7588772B2
(en)
|
2006-03-30 |
2009-09-15 |
Board Of Trustees Of The Leland Stamford Junior University |
AAV capsid library and AAV capsid proteins
|
|
DK2548438T3
(en)
|
2006-11-08 |
2015-10-19 |
Veritas Bio LLC |
IN VIVO SUBMITTING DOUBLE-STRENGTH RNA TO A CELL
|
|
EP2058401A1
(en)
|
2007-10-05 |
2009-05-13 |
Genethon |
Widespread gene delivery to motor neurons using peripheral injection of AAV vectors
|
|
CA2722238C
(en)
|
2008-04-22 |
2017-11-28 |
Life Sciences Research Partners Vzw |
Liver-specific nucleic acid regulatory elements and methods and use thereof
|
|
CA2972694C
(en)
|
2008-05-13 |
2020-02-11 |
University Of Washington |
Diblock copolymers and polynucleotide complexes thereof for delivery into cells
|
|
MX2011004242A
(es)
|
2008-11-06 |
2011-07-20 |
Univ Washington |
Copolimeros multibloque.
|
|
EP2352522A4
(en)
|
2008-11-06 |
2014-03-05 |
Univ Washington |
BISPECIFIC AUXILIARIES FOR INTRA-CELLULAR RELEASE
|
|
EP3269395A1
(en)
|
2008-11-07 |
2018-01-17 |
Massachusetts Institute Of Technology |
Aminoalcohol lipidoids and uses thereof
|
|
RS53257B2
(sr)
|
2009-07-24 |
2018-06-29 |
Immune Design Corp |
Lentiviralni vektori pseudotipizirani sa omotačem od glikobelančevine iz sindbis-virusa
|
|
EP2281579A1
(en)
|
2009-08-05 |
2011-02-09 |
BioNTech AG |
Vaccine composition comprising 5'-Cap modified RNA
|
|
WO2011126808A2
(en)
|
2010-03-29 |
2011-10-13 |
The Trustees Of The University Of Pennsylvania |
Pharmacologically induced transgene ablation system
|
|
US9315825B2
(en)
|
2010-03-29 |
2016-04-19 |
The Trustees Of The University Of Pennsylvania |
Pharmacologically induced transgene ablation system
|
|
CN103534417B
(zh)
|
2011-05-12 |
2016-03-23 |
日立建机株式会社 |
工程机械
|
|
RU2013154295A
(ru)
|
2011-06-08 |
2015-07-20 |
Шир Хьюман Дженетик Терапис, Инк. |
КОМПОЗИЦИИ ЛИПИДНЫХ НАНОЧАСТИЦ И СПОСОБЫ ДЛЯ ДОСТАВКИ мРНК
|
|
FR2977562B1
(fr)
|
2011-07-06 |
2016-12-23 |
Gaztransport Et Technigaz |
Cuve etanche et thermiquement isolante integree dans une structure porteuse
|
|
PE20181541A1
(es)
|
2011-10-27 |
2018-09-26 |
Massachusetts Inst Technology |
Derivados de aminoacidos funcionalizados en la terminal n capaces de formar microesferas encapsuladoras de farmaco
|
|
WO2013143555A1
(en)
|
2012-03-26 |
2013-10-03 |
Biontech Ag |
Rna formulation for immunotherapy
|
|
CN104411338A
(zh)
*
|
2012-04-02 |
2015-03-11 |
现代治疗公司 |
用于产生与人类疾病相关的生物制剂和蛋白质的修饰多核苷酸
|
|
WO2013151665A2
(en)
*
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of proteins associated with human disease
|
|
US20150126589A1
(en)
|
2012-06-08 |
2015-05-07 |
Ethris Gmbh |
Pulmonary Delivery of Messenger RNA
|
|
AU2014296278C1
(en)
*
|
2013-07-30 |
2023-02-02 |
Genevant Sciences Gmbh |
Block copolymers and their conjugates or complexes with oligonucleotides
|
|
SMT202000531T1
(it)
|
2014-03-09 |
2020-11-10 |
Univ Pennsylvania |
Composizioni utili in trattamento di deficit di ornitina transcarbamilasi(otc)
|