JP2020079313A5 - - Google Patents

Download PDF

Info

Publication number
JP2020079313A5
JP2020079313A5 JP2020031965A JP2020031965A JP2020079313A5 JP 2020079313 A5 JP2020079313 A5 JP 2020079313A5 JP 2020031965 A JP2020031965 A JP 2020031965A JP 2020031965 A JP2020031965 A JP 2020031965A JP 2020079313 A5 JP2020079313 A5 JP 2020079313A5
Authority
JP
Japan
Prior art keywords
iodinated
alcohol
microspheres
bifunctional linker
containing compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020031965A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020079313A (ja
JP6983930B2 (ja
Filing date
Publication date
Priority claimed from JP2018193368A external-priority patent/JP6723312B2/ja
Application filed filed Critical
Publication of JP2020079313A publication Critical patent/JP2020079313A/ja
Publication of JP2020079313A5 publication Critical patent/JP2020079313A5/ja
Application granted granted Critical
Publication of JP6983930B2 publication Critical patent/JP6983930B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020031965A 2013-03-15 2020-02-27 結像可能な塞栓性微小球 Active JP6983930B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361790373P 2013-03-15 2013-03-15
US61/790,373 2013-03-15
JP2018193368A JP6723312B2 (ja) 2013-03-15 2018-10-12 結像可能な塞栓性微小球

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2018193368A Division JP6723312B2 (ja) 2013-03-15 2018-10-12 結像可能な塞栓性微小球

Publications (3)

Publication Number Publication Date
JP2020079313A JP2020079313A (ja) 2020-05-28
JP2020079313A5 true JP2020079313A5 (https=) 2020-08-27
JP6983930B2 JP6983930B2 (ja) 2021-12-17

Family

ID=50631039

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2016502420A Active JP6420817B2 (ja) 2013-03-15 2014-03-14 結像可能な塞栓性微小球
JP2018193368A Active JP6723312B2 (ja) 2013-03-15 2018-10-12 結像可能な塞栓性微小球
JP2020031965A Active JP6983930B2 (ja) 2013-03-15 2020-02-27 結像可能な塞栓性微小球

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2016502420A Active JP6420817B2 (ja) 2013-03-15 2014-03-14 結像可能な塞栓性微小球
JP2018193368A Active JP6723312B2 (ja) 2013-03-15 2018-10-12 結像可能な塞栓性微小球

Country Status (8)

Country Link
US (3) US10307493B2 (https=)
EP (1) EP2968618B1 (https=)
JP (3) JP6420817B2 (https=)
KR (1) KR20160032000A (https=)
CN (2) CN117982687A (https=)
CA (1) CA2906574C (https=)
HK (1) HK1220119A1 (https=)
WO (1) WO2014152488A2 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2531488T3 (es) 2009-10-06 2015-03-16 Regents Of The University Of Minnesota Microesferas de embolización bioreabsorbibles
AU2013274199B2 (en) 2012-06-14 2016-08-11 Microvention, Inc. Polymeric treatment compositions
WO2014062696A1 (en) 2012-10-15 2014-04-24 Microvention, Inc. Polymeric treatment compositions
GB2519738A (en) 2013-09-06 2015-05-06 Biocompatibles Uk Ltd Radiopaque polymers
GB2521997A (en) 2013-09-06 2015-07-15 Biocompatibles Uk Ltd Radiopaque polymers
EP4245782B1 (en) 2015-01-12 2025-10-29 Biosphere Medical, Inc. Radiopaque monomers, polymers, microspheres, and methods related thereto
CN115137870B (zh) * 2016-03-14 2024-05-10 生物相容性英国公司 包含颗粒的乳液
US10182979B2 (en) 2016-03-22 2019-01-22 Regents Of The University Of Minnesota Biodegradable microspheres
US10368874B2 (en) 2016-08-26 2019-08-06 Microvention, Inc. Embolic compositions
CN107050501B (zh) * 2016-12-29 2020-09-15 苏州恒瑞迦俐生生物医药科技有限公司 一种可视化多羟基聚合体栓塞微球及其制备方法
CN106822983B (zh) * 2016-12-29 2020-09-15 苏州恒瑞迦俐生生物医药科技有限公司 一种用于微创介入疗法治疗肿瘤疾病的可显影栓塞微球及其制备方法
JP6925014B2 (ja) 2017-02-15 2021-08-25 ドリームメディカルパートナーズ株式会社 塞栓材の製造方法
JP7362598B2 (ja) 2017-10-09 2023-10-17 マイクロベンション インコーポレイテッド 放射性液体塞栓物質
CN107854720B (zh) * 2017-12-28 2020-12-08 苏州恒瑞迦俐生生物医药科技有限公司 具有造影功能的可载药多羟基聚合物栓塞微球及其制备方法
GB201810788D0 (en) 2018-06-29 2018-08-15 Biocompatibles Uk Ltd Biodegradable polymer
TW202000189A (zh) 2018-06-29 2020-01-01 英商白康帝英國有限公司 不透射線聚合物
CN108686259B (zh) * 2018-07-12 2020-11-24 中国人民解放军总医院 用于血管内栓塞x线下可显影的载药微球及其制备方法
CN113348001B (zh) * 2018-11-13 2022-10-21 上海盛迪医药有限公司 一种聚合物及其组合物
CN110628008B (zh) * 2019-06-25 2021-10-08 复旦大学 一种具有x-射线显影功能的含碘聚碳酸酯及其制备方法与应用
GB201910286D0 (en) 2019-07-18 2019-09-04 Biocompatibles Uk Ltd Radiopaque polymers
EP4026859A4 (en) * 2019-09-05 2022-12-28 Dalian Heyuan Medical Equipments Co., Ltd. Poly[alpha-cyanoacrylate] hydrolyzate and preparation method and applicaiton thereof
CN112972754B (zh) * 2021-02-24 2022-07-19 苏州微尺度科技有限公司 一种可视化岩藻多糖栓塞微球及其制备方法
US20230037198A1 (en) * 2021-07-29 2023-02-02 Varian Medical Systems, Inc. Apparatuses and methods for producing embolic particles with activated loading sites
CN116115818B (zh) * 2021-11-12 2024-06-28 重庆百迈腾世医药科技有限公司 活性金属微球、基于活性金属微球的复合栓塞剂及其应用
CN114057600B (zh) * 2021-12-02 2024-02-02 上海汇禾医疗科技股份有限公司 一种可x射线显影分子、载药栓塞微球及其制备方法
CN114344554A (zh) * 2022-02-11 2022-04-15 上海益思妙医疗器械有限公司 一种peg化合物作为制备栓塞剂的应用
CN116059368B (zh) * 2022-07-20 2025-07-25 暨南大学 Smo抑制剂在制备预防、延缓或减轻动静脉内瘘通路狭窄的药物中的应用
US20240327335A1 (en) 2022-08-25 2024-10-03 Cardiolink Science (Shenzhen) Medical Technology Development Co., Ltd. Amide compound having iodoaryl or iodoheteroaryl, preparation method therefor and use thereof
CN115490639B (zh) * 2022-09-19 2023-05-16 科睿驰(深圳)医疗科技发展有限公司 X射线显影化合物及其制备方法、x射线显影栓塞材料及其制备方法
CN117323294B (zh) * 2023-09-25 2024-05-31 至微(深圳)医学科技有限公司 一种载药栓塞微球及其制备方法和应用

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2860986A (en) 1956-08-31 1958-11-18 Eastman Kodak Co Partially acetalized polyvinyl alcohol containing active halogen
US3840482A (en) 1971-09-13 1974-10-08 Ici Australia Ltd Process for curing poly(vinyl alcohol)matrix beads
US4406878A (en) 1978-08-02 1983-09-27 Eastman Kodak Company Iodinated contrast agent for radiography
US4306031A (en) 1979-08-14 1981-12-15 Mitsubishi Chemical Industries Limited Weakly acidic cation exchange resin and process for producing same
US5141739A (en) 1986-07-03 1992-08-25 Advanced Magnetics, Inc. Delivery of x-ray contrast agents using receptor mediated endocytosis
JPH0656676B2 (ja) 1986-09-01 1994-07-27 ティアツク株式会社 記録再生装置
EP0391741B1 (en) 1989-04-06 1995-04-19 Merocel Corporation Polymeric broad-spectrum antimicrobial materials
DK0586524T3 (https=) 1991-06-03 1997-05-20 Nycomed Imaging As
JPH0656676A (ja) 1992-08-05 1994-03-01 Hori Shinichi 血管塞栓用懸濁液
US5330739A (en) 1992-12-04 1994-07-19 Sterling Winthrop Inc. Iodinated benzoyl acetals and ketals for x-ray imaging
TW272976B (https=) * 1993-08-06 1996-03-21 Ciba Geigy Ag
EP1263803B1 (en) 2000-03-13 2007-09-19 BioCure, Inc. Embolic compositions
US6652883B2 (en) 2000-03-13 2003-11-25 Biocure, Inc. Tissue bulking and coating compositions
WO2002053288A2 (en) * 2000-12-31 2002-07-11 Amersham Biosciences Ab A method for the manufacture of compositions containing low concentrations of salts
US6911219B2 (en) 2001-09-27 2005-06-28 Surgica Corporation Partially acetalized polyvinyl alcohol embolization particles, compositions containing those particles and methods of making and using them
HK1079980B (en) 2003-02-12 2008-11-14 Biocompatibles Uk Limited Composition for chemoembolotherapy of solid tumors
US20040161466A1 (en) 2003-02-14 2004-08-19 Biocompatibles Uk Limited Chemoembolisation
US7201918B2 (en) 2004-11-16 2007-04-10 Microvention, Inc. Compositions, systems and methods for treatment of defects in blood vessels
US20060292077A1 (en) 2005-03-18 2006-12-28 Zhao Jonathon Z Dendritic and star-shaped contrast agents for medical devices and bioabsorbable radiopaque bulk material and method for producing same
EP1810698A1 (en) 2006-01-24 2007-07-25 Biocompatibles UK Limited Process for producing radiopaque embolic microspheres
WO2008051291A2 (en) * 2006-04-11 2008-05-02 Ordway Research Institute Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof
US8507639B2 (en) 2006-09-11 2013-08-13 Boston Scientific Scimed, Inc. Radiopaque amide polymers and medical devices formed thereof
WO2008039827A2 (en) 2006-09-26 2008-04-03 Aeris Therapeutics, Inc. Polymer systems for lung volume reduction therapy
JPWO2008059835A1 (ja) 2006-11-16 2010-03-04 財団法人ヒューマンサイエンス振興財団 金属キレート複合体及びプロトン緩和速度増強剤並びにmri造影剤
CA2686563A1 (en) 2007-05-11 2008-11-20 Aeris Therapeutics, Llc Lung volume reduction therapy using crosslinked non-natural polymers
EP1992371A1 (de) 2007-05-15 2008-11-19 Occlutech GmbH Bioresorbierbare röntgenopake Polymermaterialien und daraus hergestellte Occlussionsinstrumente
AU2008279129A1 (en) 2007-07-24 2009-01-29 Nexbio, Inc. Technology for the preparation of microparticles
CN101835749A (zh) 2007-07-30 2010-09-15 奥斯拜客斯制药有限公司 取代的吲哚
EP2090592A1 (en) 2007-07-31 2009-08-19 OctoPlus Sciences B.V. Biodegradable hydrogels based on click chemistry
US20090169471A1 (en) * 2007-12-28 2009-07-02 Boston Scientific Scimed, Inc. Particles for injection and processes for forming the same
US20090269390A1 (en) 2008-04-25 2009-10-29 Medtronic, Inc. Medical devices, polymers, compositions, and methods for delivering a haloacetate
US8790701B2 (en) 2008-04-28 2014-07-29 Surmodics, Inc. Poly-α(1→4)glucopyranose-based matrices with hydrazide crosslinking
ITRM20080636A1 (it) 2008-11-28 2010-05-29 Univ Palermo Procedimento per la produzione di derivati funzionalizzati dell acido ialuronico e relativi idrogeli.
CA3149284A1 (en) 2009-12-15 2011-07-14 Incept, Llc Implants and biodegradable fiducial markers
EP2365009A1 (en) * 2010-03-10 2011-09-14 Universite Claude Bernard Lyon 1 (UCBL) Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof
ES2368307B1 (es) 2010-04-28 2012-10-17 Universidade De Santiago De Compostela Hidrogeles elaborados a base de polímeros aniónicos de origen natural.
CN103124762B (zh) 2010-09-29 2016-03-16 塞恩心血管公司 制备微球的方法及其制备的微球和微球的用途
JP5915177B2 (ja) * 2010-12-09 2016-05-11 東レ株式会社 生分解性粒子、血管塞栓材料及び生分解性粒子の製造方法
US9910037B2 (en) 2013-03-15 2018-03-06 Iris International, Inc. Conjugation of multiple vancomycin molecules on a polyvinyl alcohol backbone for the capture of microorganisms
JP6506230B2 (ja) 2016-09-28 2019-04-24 Necプラットフォームズ株式会社 音声無音検知装置、音声無音検知方法、音声無音検知プログラム、及び音声無音検知システム

Similar Documents

Publication Publication Date Title
JP2020079313A5 (https=)
JP2016515158A5 (https=)
US5391667A (en) Copolymers of N-vinyl-lactams suitable for oligomer solid phase synthesis
US8652335B2 (en) Scavenger supports and the use thereof in a process for the extraction of metals
PT1692206E (pt) MéTODO DE PREPARAÆO DE POLMEROS COM A FUNÆO áCIDO CARBOXLICO
US20230192931A1 (en) Host-group-containing polymerizable monomer, polymer material, method for producing same, and clathrate compound and method for producing same
US7728175B1 (en) Linear amine functionalized poly(trimethylene ether) compositions
Sashiwa et al. Highly convergent synthesis of dendrimerized chitosan− sialic acid hybrid
US7038078B2 (en) Methods of synthesizing and using derivatives of [2-(2-aminoethoxy)ethoxy] acetic acid
JPH0350744B2 (https=)
CN104909969B (zh) 一种三嵌段型中性聚合物键合剂及其制备方法
JP2009510253A (ja) 保護されたアミン塩を用いて、末端アミン基を有するポリマーを調製する方法
KR20080036236A (ko) 말단에 아민기를 갖는 중합체의 제조방법
US5354896A (en) Catalysts for reaction of epoxides and acids
US7902268B2 (en) Water soluble energy curable stereo-crosslinkable ionomer compositions
JP4689941B2 (ja) 固相合成担体および方法
JP2002066330A (ja) 金属化合物組成物
Vanier et al. Preparation of new functionalized hydrocarbon linkers via Suzuki cross coupling reaction
WO2004072019A1 (ja) イオン交換樹脂固定化白金触媒を用いたヒドロキシルアミン化合物の製造方法
JP4004756B2 (ja) 高分子架橋体およびその製造方法並びに使用方法および架橋剤
US7094853B2 (en) Crosslinked polymer, method for manufacturing it and use thereof
Kahovec et al. Chemical modification of macroreticular 2-hydroxyethyl methacrylate—Ethylene dimethacrylate copolymers
JPH0518844B2 (https=)
CN113501947A (zh) 一种带氨基聚酯及其制备方法
JP4123655B2 (ja) 多官能メタクリルオリゴマーの製造方法