JP2019533682A5 - - Google Patents
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- Publication number
- JP2019533682A5 JP2019533682A5 JP2019522273A JP2019522273A JP2019533682A5 JP 2019533682 A5 JP2019533682 A5 JP 2019533682A5 JP 2019522273 A JP2019522273 A JP 2019522273A JP 2019522273 A JP2019522273 A JP 2019522273A JP 2019533682 A5 JP2019533682 A5 JP 2019533682A5
- Authority
- JP
- Japan
- Prior art keywords
- lymphoma
- combination according
- combination
- hodgkin
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022100006A JP2022137089A (ja) | 2016-10-28 | 2022-06-22 | 抗ｃｄ１９抗体とｂｃｌ－２阻害剤との組み合わせおよびその使用 |
| JP2024125584A JP2024167208A (ja) | 2016-10-28 | 2024-08-01 | 抗ｃｄ１９抗体とｂｃｌ－２阻害剤との組み合わせおよびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16196184 | 2016-10-28 | ||
| EP16196184.2 | 2016-10-28 | ||
| PCT/EP2017/077654 WO2018078123A1 (en) | 2016-10-28 | 2017-10-27 | Combination of anti cd19 antibody with a bcl-2 inhibitor and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022100006A Division JP2022137089A (ja) | 2016-10-28 | 2022-06-22 | 抗ｃｄ１９抗体とｂｃｌ－２阻害剤との組み合わせおよびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019533682A JP2019533682A (ja) | 2019-11-21 |
| JP2019533682A5 true JP2019533682A5 (enExample) | 2020-12-03 |
| JP7094950B2 JP7094950B2 (ja) | 2022-07-04 |
Family
ID=57218739
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019522273A Active JP7094950B2 (ja) | 2016-10-28 | 2017-10-27 | 抗ｃｄ１９抗体とｂｃｌ－２阻害剤との組み合わせおよびその使用 |
| JP2022100006A Pending JP2022137089A (ja) | 2016-10-28 | 2022-06-22 | 抗ｃｄ１９抗体とｂｃｌ－２阻害剤との組み合わせおよびその使用 |
| JP2024125584A Pending JP2024167208A (ja) | 2016-10-28 | 2024-08-01 | 抗ｃｄ１９抗体とｂｃｌ－２阻害剤との組み合わせおよびその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022100006A Pending JP2022137089A (ja) | 2016-10-28 | 2022-06-22 | 抗ｃｄ１９抗体とｂｃｌ－２阻害剤との組み合わせおよびその使用 |
| JP2024125584A Pending JP2024167208A (ja) | 2016-10-28 | 2024-08-01 | 抗ｃｄ１９抗体とｂｃｌ－２阻害剤との組み合わせおよびその使用 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US12358983B2 (enExample) |
| EP (2) | EP3903821A1 (enExample) |
| JP (3) | JP7094950B2 (enExample) |
| KR (2) | KR102500868B1 (enExample) |
| CN (2) | CN109890418B (enExample) |
| AU (2) | AU2017348624B2 (enExample) |
| BR (1) | BR112019008244A2 (enExample) |
| CA (1) | CA3037246A1 (enExample) |
| CY (1) | CY1124648T1 (enExample) |
| DK (1) | DK3532098T3 (enExample) |
| ES (1) | ES2871574T3 (enExample) |
| HR (1) | HRP20210838T1 (enExample) |
| HU (1) | HUE054496T2 (enExample) |
| IL (3) | IL320372A (enExample) |
| LT (1) | LT3532098T (enExample) |
| MX (2) | MX2019004942A (enExample) |
| PL (1) | PL3532098T3 (enExample) |
| PT (1) | PT3532098T (enExample) |
| RS (1) | RS62036B1 (enExample) |
| RU (1) | RU2756405C2 (enExample) |
| SG (1) | SG10202104036QA (enExample) |
| SI (1) | SI3532098T1 (enExample) |
| SM (1) | SMT202100347T1 (enExample) |
| WO (1) | WO2018078123A1 (enExample) |
| ZA (1) | ZA201903302B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2767063C2 (ru) | 2015-08-21 | 2022-03-16 | МорфоСис АГ | Комбинации и их использование |
| US12358983B2 (en) | 2016-10-28 | 2025-07-15 | Incyte Corporation | Combination of anti CD19 antibody with a BCL-2 inhibitor and uses thereof |
| LT3630177T (lt) * | 2017-05-31 | 2023-10-25 | Morphosys Ag | Gydymo paradigma, skirta kompleksiniam gydymui anti-cd19 antikūnu ir venetoklaksu |
| GB201809746D0 (en) * | 2018-06-14 | 2018-08-01 | Berlin Chemie Ag | Pharmaceutical combinations |
| ES3037206T3 (en) * | 2018-08-31 | 2025-09-30 | Adc Therapeutics Sa | Combination therapy |
| KR20200030337A (ko) | 2018-09-12 | 2020-03-20 | 주식회사 녹십자랩셀 | 종양 치료를 위한 항-cd 19 항체 및 자연살해세포를 포함하는 약학적 조합물 |
| KR20220104176A (ko) * | 2019-10-31 | 2022-07-26 | 모르포시스 아게 | 순차적 항-cd19 요법 |
| US20220389104A1 (en) * | 2021-05-28 | 2022-12-08 | Ose Immunotherapeutics | Method for Treating CD127-Positive Cancers by Administering an Anti-CD127 Agent |
Family Cites Families (49)
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| CA1247080A (en) | 1983-03-08 | 1988-12-20 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| US5686072A (en) | 1992-06-17 | 1997-11-11 | Board Of Regents, The University Of Texas | Epitope-specific monoclonal antibodies and immunotoxins and uses thereof |
| JP2004508420A (ja) | 2000-09-18 | 2004-03-18 | アイデック ファーマスーティカルズ コーポレイション | Ｂ細胞枯渇抗体／免疫調節性抗体の組合せを用いて自己免疫疾患を治療するための併用療法 |
| US7771951B2 (en) | 2001-12-03 | 2010-08-10 | Amgen Fremont Inc. | Antibody categorization based on binding characteristics |
| CA2534639C (en) | 2003-07-31 | 2013-07-30 | Immunomedics, Inc. | Anti-cd19 antibodies |
| US7902338B2 (en) | 2003-07-31 | 2011-03-08 | Immunomedics, Inc. | Anti-CD19 antibodies |
| CA2611814A1 (en) | 2005-06-20 | 2007-01-04 | Medarex, Inc. | Cd19 antibodies and their uses |
| ES2365046T3 (es) | 2005-12-30 | 2011-09-21 | Merck Patent Gmbh | Anticuerpos anti-cd19 con inmunogenicidad reducida. |
| PL2383297T3 (pl) | 2006-08-14 | 2013-06-28 | Xencor Inc | Zoptymalizowane przeciwciała ukierunkowane na CD19 |
| ATE552204T1 (de) | 2006-08-15 | 2012-04-15 | Hydralift Amclyde Inc | Direkt wirkender einzelscheiben-aktiv/passiv- hubkompensator |
| RU2495882C2 (ru) | 2006-09-08 | 2013-10-20 | Медиммун, Ллк. | Гуманизированные антитела к cd19 и их применение для лечения онкологического, связанного с трансплантацией и аутоиммунного заболевания |
| DK2526933T3 (en) | 2006-09-22 | 2015-05-18 | Pharmacyclics Inc | Inhibitors of Bruton's tyrosine kinase |
| EP2176298B1 (en) * | 2007-05-30 | 2017-11-15 | Xencor, Inc. | Methods and compositions for inhibiting cd32b expressing cells |
| DK2211904T3 (en) | 2007-10-19 | 2016-10-24 | Seattle Genetics Inc | Cd19-binding agents and uses thereof |
| US20100128586A1 (en) | 2008-11-25 | 2010-05-27 | Mediatek Inc. | Method and apparatus for accessing data from disc with linking area |
| CN102421800A (zh) | 2009-02-23 | 2012-04-18 | 格兰马克药品股份有限公司 | 结合cd19的人源化抗体及其用途 |
| US8546399B2 (en) | 2009-05-26 | 2013-10-01 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
| AU2010263272C1 (en) | 2009-06-24 | 2016-02-11 | The Feinstein Institute For Medical Research | Method for treating chronic lymphocytic leukemia |
| WO2011147834A1 (en) | 2010-05-26 | 2011-12-01 | Roche Glycart Ag | Antibodies against cd19 and uses thereof |
| CA3007787C (en) | 2010-06-03 | 2020-03-10 | Pharmacyclics Llc | The use of inhibitors of bruton's tyrosine kinase (btk) |
| EP2409993A1 (en) | 2010-07-19 | 2012-01-25 | International-Drug-Development-Biotech | Anti-CD19 antibody having ADCC function with improved glycosylation profile |
| EP2409712A1 (en) | 2010-07-19 | 2012-01-25 | International-Drug-Development-Biotech | Anti-CD19 antibody having ADCC and CDC functions and improved glycosylation profile |
| US8549399B2 (en) | 2011-01-18 | 2013-10-01 | Apple Inc. | Identifying a selection of content in a structured document |
| EP2524929A1 (en) | 2011-05-17 | 2012-11-21 | Sanofi | Use of anti-CD19 maytansinoid immunoconjugate antibody for the treatment of CD19+ B-cell malignancies syptoms |
| HRP20220224T1 (hr) | 2011-08-16 | 2022-04-29 | Morphosys Ag | Kombinacijska terapija s protutijelom anti-cd19 i dušičnim alkilirajućim agensom |
| KR20140064873A (ko) | 2011-08-16 | 2014-05-28 | 모르포시스 아게 | 항-cd19 항체 및 질소 머스타드를 사용한 조합 요법 |
| WO2015082583A1 (en) * | 2013-12-05 | 2015-06-11 | F. Hoffmann-La Roche Ag | Heteroaryl pyridone and aza-pyridone compounds with electrophilic functionality |
| EP3476392A1 (en) * | 2014-02-28 | 2019-05-01 | Merck Sharp & Dohme Corp. | Method for treating cancer |
| AU2015244039B2 (en) * | 2014-04-07 | 2021-10-21 | Novartis Ag | Treatment of cancer using anti-CD19 chimeric antigen receptor |
| AU2015277516A1 (en) | 2014-06-16 | 2016-12-22 | Xencor, Inc. | Treatment for chronic lymphocytic leukemia (CLL) |
| MX392487B (es) | 2014-10-20 | 2025-03-21 | Juno Therapeutics Inc | Métodos y composiciones para dosificación en terapia celular adoptiva. |
| CN107406507A (zh) * | 2015-02-12 | 2017-11-28 | 西雅图基因公司 | 使用cd19‑adc和长春新碱的组合疗法 |
| PE20180454A1 (es) | 2015-05-26 | 2018-03-05 | Hoffmann La Roche | Terapia combinada de un anticuerpo anti-cd20 con un inhibidor de bcl-2 y un inhibidor de mdm2 |
| LT3302550T (lt) | 2015-05-26 | 2019-11-11 | Morphosys Ag | Anti-cd19 antikūno ir brutono tirozino kinazės inhibitoriaus derinys ir jo naudojimas |
| US10973822B2 (en) | 2015-07-02 | 2021-04-13 | Celgene Corporation | Combination therapy for treatment of hematological cancers and solid tumors |
| RU2767063C2 (ru) | 2015-08-21 | 2022-03-16 | МорфоСис АГ | Комбинации и их использование |
| FI3916392T3 (fi) | 2016-05-30 | 2024-06-03 | Incyte Corp | Menetelmiä cd19-vasta-ainehoidon terapeuttisen hyödyn ennakoimiseksi potilailla |
| WO2018002031A1 (en) | 2016-06-27 | 2018-01-04 | Morphosys Ag | Anti-cd19 antibody formulations |
| US12358983B2 (en) | 2016-10-28 | 2025-07-15 | Incyte Corporation | Combination of anti CD19 antibody with a BCL-2 inhibitor and uses thereof |
| LT3630177T (lt) | 2017-05-31 | 2023-10-25 | Morphosys Ag | Gydymo paradigma, skirta kompleksiniam gydymui anti-cd19 antikūnu ir venetoklaksu |
| US20210292410A1 (en) | 2017-12-07 | 2021-09-23 | Morphosys Ag | Treatment paradigm for an anti-cd19 antibody and venetoclax combination treatment |
| KR20200030337A (ko) | 2018-09-12 | 2020-03-20 | 주식회사 녹십자랩셀 | 종양 치료를 위한 항-cd 19 항체 및 자연살해세포를 포함하는 약학적 조합물 |
| AU2020267823A1 (en) | 2019-05-03 | 2021-11-11 | Incyte Corporation | Anti-CD19 therapy in patients having a limited number of NK cells |
| CN115151565A (zh) | 2019-10-31 | 2022-10-04 | 莫佛塞斯公司 | 包含抗CD19抗体和γδT细胞的抗肿瘤组合疗法 |
| TW202525340A (zh) | 2019-10-31 | 2025-07-01 | 美商英塞特公司 | 用於治療白血病或淋巴瘤之抗cd19療法與來那度胺(lenalidomide)的組合 |
| KR20220104176A (ko) | 2019-10-31 | 2022-07-26 | 모르포시스 아게 | 순차적 항-cd19 요법 |
| WO2021259902A1 (en) | 2020-06-22 | 2021-12-30 | Morphosys Ag | Anti-tumor combination therapy comprising anti-cd19 antibody and polypeptides blocking the sirpα-cd47 innate immune checkpoint |
| WO2022117799A2 (en) | 2020-12-04 | 2022-06-09 | Morphosys Ag | Anti-cd19 combination therapy |
| CA3255552A1 (en) | 2021-12-22 | 2023-06-29 | Incyte Corporation | TREATMENT PARADIGM FOR ANTI-CD19 ANTIBODY THERAPY |
-
2017
- 2017-10-27 US US16/342,645 patent/US12358983B2/en active Active
- 2017-10-27 RU RU2019113370A patent/RU2756405C2/ru active
- 2017-10-27 SM SM20210347T patent/SMT202100347T1/it unknown
- 2017-10-27 CN CN201780067047.1A patent/CN109890418B/zh active Active
- 2017-10-27 WO PCT/EP2017/077654 patent/WO2018078123A1/en not_active Ceased
- 2017-10-27 IL IL320372A patent/IL320372A/en unknown
- 2017-10-27 AU AU2017348624A patent/AU2017348624B2/en active Active
- 2017-10-27 ES ES17797564T patent/ES2871574T3/es active Active
- 2017-10-27 SG SG10202104036QA patent/SG10202104036QA/en unknown
- 2017-10-27 PT PT177975646T patent/PT3532098T/pt unknown
- 2017-10-27 RS RS20210792A patent/RS62036B1/sr unknown
- 2017-10-27 KR KR1020197012532A patent/KR102500868B1/ko active Active
- 2017-10-27 DK DK17797564.6T patent/DK3532098T3/da active
- 2017-10-27 CN CN202410183851.8A patent/CN118045175A/zh active Pending
- 2017-10-27 EP EP21165598.0A patent/EP3903821A1/en active Pending
- 2017-10-27 CA CA3037246A patent/CA3037246A1/en active Pending
- 2017-10-27 IL IL301786A patent/IL301786B2/en unknown
- 2017-10-27 PL PL17797564T patent/PL3532098T3/pl unknown
- 2017-10-27 IL IL266216A patent/IL266216B2/en unknown
- 2017-10-27 JP JP2019522273A patent/JP7094950B2/ja active Active
- 2017-10-27 KR KR1020237005018A patent/KR20230028571A/ko not_active Ceased
- 2017-10-27 EP EP17797564.6A patent/EP3532098B1/en active Active
- 2017-10-27 MX MX2019004942A patent/MX2019004942A/es unknown
- 2017-10-27 LT LTEP17797564.6T patent/LT3532098T/lt unknown
- 2017-10-27 SI SI201730811T patent/SI3532098T1/sl unknown
- 2017-10-27 BR BR112019008244-1A patent/BR112019008244A2/pt unknown
- 2017-10-27 HR HRP20210838TT patent/HRP20210838T1/hr unknown
- 2017-10-27 HU HUE17797564A patent/HUE054496T2/hu unknown
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2019
- 2019-04-26 MX MX2022016270A patent/MX2022016270A/es unknown
- 2019-05-24 ZA ZA2019/03302A patent/ZA201903302B/en unknown
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2021
- 2021-06-10 CY CY20211100512T patent/CY1124648T1/el unknown
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2022
- 2022-06-22 JP JP2022100006A patent/JP2022137089A/ja active Pending
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2024
- 2024-08-01 JP JP2024125584A patent/JP2024167208A/ja active Pending
- 2024-12-23 AU AU2024287178A patent/AU2024287178A1/en active Pending