JP2019517485A5 - - Google Patents

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Publication number
JP2019517485A5
JP2019517485A5 JP2018562232A JP2018562232A JP2019517485A5 JP 2019517485 A5 JP2019517485 A5 JP 2019517485A5 JP 2018562232 A JP2018562232 A JP 2018562232A JP 2018562232 A JP2018562232 A JP 2018562232A JP 2019517485 A5 JP2019517485 A5 JP 2019517485A5
Authority
JP
Japan
Prior art keywords
combination
fluoro
weeks
administered
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018562232A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019517485A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/034855 external-priority patent/WO2017205843A1/en
Publication of JP2019517485A publication Critical patent/JP2019517485A/ja
Publication of JP2019517485A5 publication Critical patent/JP2019517485A5/ja
Pending legal-status Critical Current

Links

JP2018562232A 2016-05-27 2017-05-26 B細胞増殖性障害を治療するための抗cd20抗体、p13キナーゼ−デルタ選択的阻害剤およびbtk阻害剤の組み合わせ Pending JP2019517485A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662342822P 2016-05-27 2016-05-27
US62/342,822 2016-05-27
PCT/US2017/034855 WO2017205843A1 (en) 2016-05-27 2017-05-26 Combination of anti-cd20 antibody, p13 kinase-delta selective inhibitor, and btk inhibitor to treat b-cell proliferative disorders

Publications (2)

Publication Number Publication Date
JP2019517485A JP2019517485A (ja) 2019-06-24
JP2019517485A5 true JP2019517485A5 (enExample) 2020-07-02

Family

ID=60412660

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018562232A Pending JP2019517485A (ja) 2016-05-27 2017-05-26 B細胞増殖性障害を治療するための抗cd20抗体、p13キナーゼ−デルタ選択的阻害剤およびbtk阻害剤の組み合わせ

Country Status (14)

Country Link
US (2) US10966977B2 (enExample)
EP (1) EP3463318A4 (enExample)
JP (1) JP2019517485A (enExample)
KR (1) KR20190015351A (enExample)
CN (1) CN109640964A (enExample)
AU (1) AU2017268839A1 (enExample)
BR (1) BR112018074238A2 (enExample)
CA (1) CA3024123A1 (enExample)
CL (1) CL2018003349A1 (enExample)
EA (1) EA201892284A1 (enExample)
IL (1) IL263239A (enExample)
MX (1) MX2018014577A (enExample)
SG (1) SG11201810333UA (enExample)
WO (1) WO2017205843A1 (enExample)

Families Citing this family (12)

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PL3892302T3 (pl) 2015-04-06 2024-03-11 Janssen Pharmaceutica Nv Kompozycje zawierające ibrutynib
KR102436875B1 (ko) * 2017-12-08 2022-08-26 주식회사 보령 Pi3 키나아제 억제제 및 bcl-2 억제제를 포함하는 조성물
AU2019265019B2 (en) 2018-05-11 2025-11-06 Beam Therapeutics Inc. Methods of substituting pathogenic amino acids using programmable base editor systems
KR20250125432A (ko) * 2018-06-15 2025-08-21 얀센 파마슈티카 엔브이 이브루티닙을 포함하는 제형/조성물
CN108743947B (zh) * 2018-07-04 2020-12-15 复旦大学附属肿瘤医院 一种治疗b细胞淋巴瘤的药物组合物
CN114127074A (zh) * 2019-07-15 2022-03-01 庄信万丰股份有限公司 无定形乌帕拉尼单甲苯磺酸盐
WO2022104150A1 (en) 2020-11-12 2022-05-19 Tg Therapeutics, Inc. Triple combination to treat b-cell malignancies
EP4319771A4 (en) * 2021-04-08 2025-01-01 Artiva Biotherapeutics, Inc. CANCER TREATMENT WITH NK CELLS AND AN ANTIBODY TARGETING HER2
US11965032B1 (en) 2022-06-01 2024-04-23 Tg Therapeutics, Inc. Anti-CD20 antibody compositions
US11814439B1 (en) 2022-06-01 2023-11-14 Tg Therapeutics, Inc. Anti-CD20 antibody compositions
US11884740B1 (en) 2022-06-01 2024-01-30 Tg Therapeutics, Inc. Anti-CD20 antibody compositions
US11807689B1 (en) 2022-06-01 2023-11-07 Tg Therapeutics, Inc. Anti-CD20 antibody compositions

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
US5736137A (en) 1992-11-13 1998-04-07 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
US6326469B1 (en) 1994-04-22 2001-12-04 Sugen, Inc. Megakaryocytic protein tyrosine kinases
WO1999004705A1 (en) 1997-07-25 1999-02-04 Tsui Ban C H Devices, systems and methods for determining proper placement of epidural catheters
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
FR2844455B1 (fr) 2002-09-13 2007-12-14 Lab Francais Du Fractionnement Traitement des pathologies echappant a la reponse immune par des anticorps optimises
EP1944320A1 (en) 2002-12-16 2008-07-16 Genentech, Inc. Immunoglobulin variants and uses thereof
FR2858235B1 (fr) 2003-07-31 2006-02-17 Lab Francais Du Fractionnement Utilisation d'anticorps optimises en adcc pour traiter les patients faibles repondeurs
US7663057B2 (en) 2004-02-19 2010-02-16 Nanosolar, Inc. Solution-based fabrication of photovoltaic cell
FR2879204B1 (fr) 2004-12-15 2007-02-16 Lab Francais Du Fractionnement Anticorps cytotoxique dirige contre les proliferations hematopoietiques lymphoides de type b.
US8543180B2 (en) 2006-05-03 2013-09-24 Covidien Lp Method and apparatus for total hemoglobin measurement
PL2526933T3 (pl) 2006-09-22 2015-08-31 Pharmacyclics Llc Inhibitory kinazy tyrozynowej Brutona
SG10201500895XA (en) 2009-11-05 2015-04-29 Rhizen Pharmaceuticals Sa Chromen-4-one Derivatives As Kinase Modulators
CN109970742A (zh) 2012-07-04 2019-07-05 理森制药股份公司 选择性PI3Kδ抑制剂
EP3756686A1 (en) 2012-11-02 2020-12-30 TG Therapeutics Inc. Combination of anti-cd20 antibody and pi3 kinase selective inhibitor
US10272083B2 (en) 2014-01-21 2019-04-30 Acerta Pharma B.V. Methods of treating chronic lymphocytic leukemia and small lymphocytic leukemia using a BTK inhibitor
CA2942528A1 (en) 2014-03-20 2015-09-24 Pharmacyclics Inc. Phospholipase c gamma 2 and resistance associated mutations
WO2015181728A1 (en) 2014-05-27 2015-12-03 Rhizen Pharmaceuticals Sa Improved forms of a pi3k delta selective inhibitor for use in pharmaceutical formulations
AU2015300966A1 (en) 2014-08-08 2017-02-16 Janssen Pharmaceutica Nv Bruton's tyrosine kinase inhibitor combinations and uses thereof
US20170224819A1 (en) * 2014-08-11 2017-08-10 Acerta Pharma B.V. Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a CDK 4/6 Inhibitor

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Bofill et al. American Society of Hematology (ASH)-56Th Annual Meeting and Exposition-San Francisco, California, USA, December 6-9, 2014