JP2019517485A5 - - Google Patents

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Publication number
JP2019517485A5
JP2019517485A5 JP2018562232A JP2018562232A JP2019517485A5 JP 2019517485 A5 JP2019517485 A5 JP 2019517485A5 JP 2018562232 A JP2018562232 A JP 2018562232A JP 2018562232 A JP2018562232 A JP 2018562232A JP 2019517485 A5 JP2019517485 A5 JP 2019517485A5
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JP
Japan
Prior art keywords
combination
fluoro
weeks
administered
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018562232A
Other languages
English (en)
Japanese (ja)
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JP2019517485A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/034855 external-priority patent/WO2017205843A1/en
Publication of JP2019517485A publication Critical patent/JP2019517485A/ja
Publication of JP2019517485A5 publication Critical patent/JP2019517485A5/ja
Pending legal-status Critical Current

Links

JP2018562232A 2016-05-27 2017-05-26 B細胞増殖性障害を治療するための抗cd20抗体、p13キナーゼ−デルタ選択的阻害剤およびbtk阻害剤の組み合わせ Pending JP2019517485A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662342822P 2016-05-27 2016-05-27
US62/342,822 2016-05-27
PCT/US2017/034855 WO2017205843A1 (en) 2016-05-27 2017-05-26 Combination of anti-cd20 antibody, p13 kinase-delta selective inhibitor, and btk inhibitor to treat b-cell proliferative disorders

Publications (2)

Publication Number Publication Date
JP2019517485A JP2019517485A (ja) 2019-06-24
JP2019517485A5 true JP2019517485A5 (enExample) 2020-07-02

Family

ID=60412660

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018562232A Pending JP2019517485A (ja) 2016-05-27 2017-05-26 B細胞増殖性障害を治療するための抗cd20抗体、p13キナーゼ−デルタ選択的阻害剤およびbtk阻害剤の組み合わせ

Country Status (14)

Country Link
US (2) US10966977B2 (enExample)
EP (1) EP3463318A4 (enExample)
JP (1) JP2019517485A (enExample)
KR (1) KR20190015351A (enExample)
CN (1) CN109640964A (enExample)
AU (1) AU2017268839A1 (enExample)
BR (1) BR112018074238A2 (enExample)
CA (1) CA3024123A1 (enExample)
CL (1) CL2018003349A1 (enExample)
EA (1) EA201892284A1 (enExample)
IL (1) IL263239A (enExample)
MX (1) MX2018014577A (enExample)
SG (1) SG11201810333UA (enExample)
WO (1) WO2017205843A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3892302T1 (sl) 2015-04-06 2023-11-30 Janssen Pharmaceutica Nv Sestavki, ki vsebujejo ibrutinib
WO2019112381A1 (ko) * 2017-12-08 2019-06-13 보령제약 주식회사 Pi3 키나아제 억제제 및 bcl-2 억제제를 포함하는 조성물
KR20250134703A (ko) 2018-05-11 2025-09-11 빔 테라퓨틱스, 인크. 프로그래밍가능한 염기 편집기 시스템을 이용하여 병원성 아미노산을 치환하는 방법
KR102844084B1 (ko) * 2018-06-15 2025-08-07 얀센 파마슈티카 엔브이 이브루티닙을 포함하는 제형/조성물
CN108743947B (zh) * 2018-07-04 2020-12-15 复旦大学附属肿瘤医院 一种治疗b细胞淋巴瘤的药物组合物
WO2021009509A1 (en) * 2019-07-15 2021-01-21 Johnson Matthey Public Limited Company Amorphous umbralisib monotosylate
US20220143026A1 (en) 2020-11-12 2022-05-12 Tg Therapeutics, Inc. Triple combination to treat b-cell malignancies
US20240197778A1 (en) * 2021-04-08 2024-06-20 Artiva Biotherapeutics, Inc. Treatment of cancer with nk cells and a her2 targeted antibody
US11814439B1 (en) 2022-06-01 2023-11-14 Tg Therapeutics, Inc. Anti-CD20 antibody compositions
US11884740B1 (en) 2022-06-01 2024-01-30 Tg Therapeutics, Inc. Anti-CD20 antibody compositions
US11965032B1 (en) 2022-06-01 2024-04-23 Tg Therapeutics, Inc. Anti-CD20 antibody compositions
US11807689B1 (en) 2022-06-01 2023-11-07 Tg Therapeutics, Inc. Anti-CD20 antibody compositions

Family Cites Families (22)

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US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
US5736137A (en) 1992-11-13 1998-04-07 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
US6326469B1 (en) 1994-04-22 2001-12-04 Sugen, Inc. Megakaryocytic protein tyrosine kinases
US6190370B1 (en) 1997-07-25 2001-02-20 Arrow International, Inc. Devices, systems and methods for determining proper placement of epidural catheters
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
FR2844455B1 (fr) 2002-09-13 2007-12-14 Lab Francais Du Fractionnement Traitement des pathologies echappant a la reponse immune par des anticorps optimises
ES2347241T3 (es) 2002-12-16 2010-10-27 Genentech, Inc. Variantes de inmunoglobulina y sus utilizaciones.
FR2858235B1 (fr) 2003-07-31 2006-02-17 Lab Francais Du Fractionnement Utilisation d'anticorps optimises en adcc pour traiter les patients faibles repondeurs
US7663057B2 (en) 2004-02-19 2010-02-16 Nanosolar, Inc. Solution-based fabrication of photovoltaic cell
FR2879204B1 (fr) 2004-12-15 2007-02-16 Lab Francais Du Fractionnement Anticorps cytotoxique dirige contre les proliferations hematopoietiques lymphoides de type b.
US8543180B2 (en) 2006-05-03 2013-09-24 Covidien Lp Method and apparatus for total hemoglobin measurement
EA018573B1 (ru) 2006-09-22 2013-09-30 Фармасайкликс, Инк. Ингибиторы тирозинкиназы брутона
PT2496567T (pt) 2009-11-05 2017-11-15 Rhizen Pharmaceuticals S A Novos moduladores de quinase benzopiran
KR101988079B1 (ko) 2012-07-04 2019-06-11 리젠 파마슈티컬스 소시에떼 아노님 선택적 pi3k 델타 억제제
US9694071B2 (en) * 2012-11-02 2017-07-04 Tg Therapeutics, Inc. Combination of anti-CD20 antibody and PI3 kinase selective inhibitor
US10272083B2 (en) 2014-01-21 2019-04-30 Acerta Pharma B.V. Methods of treating chronic lymphocytic leukemia and small lymphocytic leukemia using a BTK inhibitor
EP3119910A4 (en) 2014-03-20 2018-02-21 Pharmacyclics LLC Phospholipase c gamma 2 and resistance associated mutations
CA2949932C (en) 2014-05-27 2021-08-10 Rhizen Pharmaceuticals Sa Improved forms of a pi3k delta selective inhibitor for use in pharmaceutical formulations
JP2017523207A (ja) 2014-08-08 2017-08-17 ファーマサイクリックス エルエルシー ブルトン型チロシンキナーゼ阻害薬の組み合わせ及びそれらの使用
AR101504A1 (es) 2014-08-11 2016-12-21 Acerta Pharma Bv Combinaciones terapéuticas de un inhibidor de la btk, un inhibidor de la pi3k, un inhibidor de la jak-2, y/o un inhibidor de la cdk4/6

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Bofill et al. American Society of Hematology (ASH)-56Th Annual Meeting and Exposition-San Francisco, California, USA, December 6-9, 2014