JP2019530430A5 - - Google Patents

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JP2019530430A5
JP2019530430A5 JP2018569138A JP2018569138A JP2019530430A5 JP 2019530430 A5 JP2019530430 A5 JP 2019530430A5 JP 2018569138 A JP2018569138 A JP 2018569138A JP 2018569138 A JP2018569138 A JP 2018569138A JP 2019530430 A5 JP2019530430 A5 JP 2019530430A5
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acid sequence
amino acid
heterodimer
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JP7308034B2 (ja
JP2019530430A (ja
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Priority claimed from PCT/US2017/040267 external-priority patent/WO2018005954A2/en
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Priority to JP2022122570A priority Critical patent/JP2022153588A/ja
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Priority to JP2023208402A priority patent/JP2024026334A/ja
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JP2018569138A 2016-07-01 2017-06-30 最適化二重ヌクレアーゼ融合物および方法 Active JP7308034B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022122570A JP2022153588A (ja) 2016-07-01 2022-08-01 最適化二重ヌクレアーゼ融合物および方法
JP2023208402A JP2024026334A (ja) 2016-07-01 2023-12-11 最適化二重ヌクレアーゼ融合物および方法

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US201662357756P 2016-07-01 2016-07-01
US62/357,756 2016-07-01
PCT/US2017/040267 WO2018005954A2 (en) 2016-07-01 2017-06-30 Optimized binuclease fusions and methods

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JP2022122570A Division JP2022153588A (ja) 2016-07-01 2022-08-01 最適化二重ヌクレアーゼ融合物および方法

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JP2019530430A JP2019530430A (ja) 2019-10-24
JP2019530430A5 true JP2019530430A5 (cg-RX-API-DMAC7.html) 2020-08-06
JP7308034B2 JP7308034B2 (ja) 2023-07-13

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JP2018569138A Active JP7308034B2 (ja) 2016-07-01 2017-06-30 最適化二重ヌクレアーゼ融合物および方法
JP2022122570A Pending JP2022153588A (ja) 2016-07-01 2022-08-01 最適化二重ヌクレアーゼ融合物および方法
JP2023208402A Pending JP2024026334A (ja) 2016-07-01 2023-12-11 最適化二重ヌクレアーゼ融合物および方法

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JP2022122570A Pending JP2022153588A (ja) 2016-07-01 2022-08-01 最適化二重ヌクレアーゼ融合物および方法
JP2023208402A Pending JP2024026334A (ja) 2016-07-01 2023-12-11 最適化二重ヌクレアーゼ融合物および方法

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US (4) US20190241878A1 (cg-RX-API-DMAC7.html)
EP (2) EP3478830B1 (cg-RX-API-DMAC7.html)
JP (3) JP7308034B2 (cg-RX-API-DMAC7.html)
CN (2) CN109790526A (cg-RX-API-DMAC7.html)
AU (2) AU2017290389B2 (cg-RX-API-DMAC7.html)
CA (1) CA3029627A1 (cg-RX-API-DMAC7.html)
DK (1) DK3478830T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20240603T1 (cg-RX-API-DMAC7.html)
MA (1) MA45554A (cg-RX-API-DMAC7.html)
WO (1) WO2018005954A2 (cg-RX-API-DMAC7.html)

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AU2012249360B2 (en) 2011-04-29 2015-12-24 University Of Washington Therapeutic nuclease compositions and methods
WO2015066550A1 (en) 2013-10-31 2015-05-07 Resolve Therapeutics, Llc Therapeutic nuclease-albumin fusions and methods
US20190241878A1 (en) 2016-07-01 2019-08-08 Resolve Therapeutics, Llc Optimized binuclease fusions and methods
CN111315767B (zh) 2017-08-22 2025-03-18 萨纳生物有限责任公司 可溶性干扰素受体及其用途
CN113597319A (zh) * 2019-01-04 2021-11-02 分解治疗有限责任公司 用核酸酶融合蛋白治疗干燥症
KR20220152196A (ko) * 2020-01-11 2022-11-15 예일 유니버시티 DNAse1 및/또는 DNAse1L3 결핍에 의해 야기되거나 이와 관련된 질병 또는 장애를 치료, 개선 및/또는 예방하기 위한 조성물 및 방법
US20230226158A1 (en) * 2020-06-08 2023-07-20 Yale University Compositions and methods for treating and/or preventing coagulopathy and/or sepsis in patients suffering from bacterial and/or viral infections
CN112322607B (zh) * 2020-11-20 2023-03-28 江南大学 一种融合型腈水合酶及其应用
EP4294827A1 (en) 2021-02-19 2023-12-27 Theripion, Inc. Paraoxonase fusion polypeptides and related compositions and methods
WO2025147696A1 (en) * 2024-01-05 2025-07-10 Resolve Therapeutics, Llc Treatment of symptoms associated with sars-cov viral infection or a prior sars-cov viral infection with nuclease agents
US12416020B2 (en) * 2024-02-20 2025-09-16 Wyvern Pharmaceuticals Inc. Plasmid encoding a TLR3 and Fc fusion protein

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