BRPI0920743A2 - ribonucleases terapeuticas - Google Patents

ribonucleases terapeuticas

Info

Publication number
BRPI0920743A2
BRPI0920743A2 BRPI0920743A BRPI0920743A BRPI0920743A2 BR PI0920743 A2 BRPI0920743 A2 BR PI0920743A2 BR PI0920743 A BRPI0920743 A BR PI0920743A BR PI0920743 A BRPI0920743 A BR PI0920743A BR PI0920743 A2 BRPI0920743 A2 BR PI0920743A2
Authority
BR
Brazil
Prior art keywords
ribonucleases
therapeutic
therapeutic ribonucleases
Prior art date
Application number
BRPI0920743A
Other languages
English (en)
Inventor
John Kink
Laura Strong
Tony Klink
Original Assignee
Quintessence Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quintessence Biosciences Inc filed Critical Quintessence Biosciences Inc
Publication of BRPI0920743A2 publication Critical patent/BRPI0920743A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/26—Endoribonucleases producing 5'-phosphomonoesters (3.1.26)
    • C12Y301/2601—Ribonuclease IX (3.1.26.10)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/27—Endoribonucleases producing 3'-phosphomonoesters (3.1.27)
    • C12Y301/27005—Pancreatic ribonuclease (3.1.27.5)
BRPI0920743A 2008-10-01 2009-10-01 ribonucleases terapeuticas BRPI0920743A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10190508P 2008-10-01 2008-10-01
PCT/US2009/059268 WO2010039985A1 (en) 2008-10-01 2009-10-01 Therapeutic Ribonucleases

Publications (1)

Publication Number Publication Date
BRPI0920743A2 true BRPI0920743A2 (pt) 2016-09-20

Family

ID=42057730

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0920743A BRPI0920743A2 (pt) 2008-10-01 2009-10-01 ribonucleases terapeuticas

Country Status (6)

Country Link
US (5) US8029782B2 (pt)
EP (1) EP2334695B1 (pt)
JP (2) JP2012504423A (pt)
CN (1) CN102227443B (pt)
BR (1) BRPI0920743A2 (pt)
WO (1) WO2010039985A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8470315B2 (en) 2004-04-13 2013-06-25 Quintessence Biosciences, Inc. Non-natural ribonuclease conjugates as cytotoxic agents
EP1896579A2 (en) 2005-06-16 2008-03-12 Wisconsin Alumni Research Foundation Cytotoxic ribonuclease variants
US7416875B2 (en) 2005-06-16 2008-08-26 Wisconsin Alumni Research Foundation Cytotoxic ribonuclease variants
EP2044097A4 (en) 2006-06-23 2010-10-06 Quintessence Biosciences Inc MODIFIED RIBONUCLEASES
WO2008010991A2 (en) 2006-07-17 2008-01-24 Quintessence Biosciences, Inc. Methods and compositions for the treatment of cancer
US8029782B2 (en) 2008-10-01 2011-10-04 Quintessence Biosciences, Inc. Therapeutic ribonucleases
MX341084B (es) 2009-11-02 2016-08-05 Univ Washington Composiciones de nucleasas terapéuticas y métodos.
EP2704737B1 (en) 2011-04-29 2018-01-10 University of Washington Therapeutic nuclease compositions and methods
US10988745B2 (en) 2013-10-31 2021-04-27 Resolve Therapeutics, Llc Therapeutic nuclease-albumin fusions and methods

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Also Published As

Publication number Publication date
US20100080789A1 (en) 2010-04-01
US8029782B2 (en) 2011-10-04
WO2010039985A1 (en) 2010-04-08
CN102227443A (zh) 2011-10-26
JP2015187139A (ja) 2015-10-29
EP2334695B1 (en) 2015-12-23
US8628768B2 (en) 2014-01-14
EP2334695A4 (en) 2012-05-23
CN102227443B (zh) 2014-05-14
US9006407B2 (en) 2015-04-14
US20120003150A1 (en) 2012-01-05
JP2012504423A (ja) 2012-02-23
US8216567B2 (en) 2012-07-10
JP6014206B2 (ja) 2016-10-25
US20150209415A1 (en) 2015-07-30
US20120276077A1 (en) 2012-11-01
US9579365B2 (en) 2017-02-28
US20140128457A1 (en) 2014-05-08
EP2334695A1 (en) 2011-06-22

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