AU2017290389B2 - Optimized binuclease fusions and methods - Google Patents

Optimized binuclease fusions and methods Download PDF

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AU2017290389B2
AU2017290389B2 AU2017290389A AU2017290389A AU2017290389B2 AU 2017290389 B2 AU2017290389 B2 AU 2017290389B2 AU 2017290389 A AU2017290389 A AU 2017290389A AU 2017290389 A AU2017290389 A AU 2017290389A AU 2017290389 B2 AU2017290389 B2 AU 2017290389B2
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binuclease
optimized
polypeptide
amino acid
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AU2017290389A1 (en
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Chris GABEL
Sanjay Patel
James Arthur Posada
Weihong Yu
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Resolve Therapeutics LLC
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Resolve Therapeutics LLC
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    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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AU2017290389A 2016-07-01 2017-06-30 Optimized binuclease fusions and methods Active AU2017290389B2 (en)

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US201662357756P 2016-07-01 2016-07-01
US62/357,756 2016-07-01
PCT/US2017/040267 WO2018005954A2 (en) 2016-07-01 2017-06-30 Optimized binuclease fusions and methods

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EP (2) EP3478830B1 (cg-RX-API-DMAC7.html)
JP (3) JP7308034B2 (cg-RX-API-DMAC7.html)
CN (2) CN109790526A (cg-RX-API-DMAC7.html)
AU (2) AU2017290389B2 (cg-RX-API-DMAC7.html)
CA (1) CA3029627A1 (cg-RX-API-DMAC7.html)
DK (1) DK3478830T3 (cg-RX-API-DMAC7.html)
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WO2015066550A1 (en) 2013-10-31 2015-05-07 Resolve Therapeutics, Llc Therapeutic nuclease-albumin fusions and methods
US20190241878A1 (en) 2016-07-01 2019-08-08 Resolve Therapeutics, Llc Optimized binuclease fusions and methods
CN111315767B (zh) 2017-08-22 2025-03-18 萨纳生物有限责任公司 可溶性干扰素受体及其用途
CN113597319A (zh) * 2019-01-04 2021-11-02 分解治疗有限责任公司 用核酸酶融合蛋白治疗干燥症
KR20220152196A (ko) * 2020-01-11 2022-11-15 예일 유니버시티 DNAse1 및/또는 DNAse1L3 결핍에 의해 야기되거나 이와 관련된 질병 또는 장애를 치료, 개선 및/또는 예방하기 위한 조성물 및 방법
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CN112322607B (zh) * 2020-11-20 2023-03-28 江南大学 一种融合型腈水合酶及其应用
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WO2025147696A1 (en) * 2024-01-05 2025-07-10 Resolve Therapeutics, Llc Treatment of symptoms associated with sars-cov viral infection or a prior sars-cov viral infection with nuclease agents
US12416020B2 (en) * 2024-02-20 2025-09-16 Wyvern Pharmaceuticals Inc. Plasmid encoding a TLR3 and Fc fusion protein

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WO2012149440A2 (en) * 2011-04-29 2012-11-01 University Of Washington Therapeutic nuclease compositions and methods

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