JP2019525136A5 - - Google Patents
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- JP2019525136A5 JP2019525136A5 JP2018564267A JP2018564267A JP2019525136A5 JP 2019525136 A5 JP2019525136 A5 JP 2019525136A5 JP 2018564267 A JP2018564267 A JP 2018564267A JP 2018564267 A JP2018564267 A JP 2018564267A JP 2019525136 A5 JP2019525136 A5 JP 2019525136A5
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- Prior art keywords
- atps
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- phase solution
- probe
- nucleic acid
- Prior art date
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- 239000000523 sample Substances 0.000 claims 48
- 239000003153 chemical reaction reagent Substances 0.000 claims 25
- 108020004707 nucleic acids Proteins 0.000 claims 22
- 102000039446 nucleic acids Human genes 0.000 claims 22
- 150000007523 nucleic acids Chemical class 0.000 claims 22
- 239000012491 analyte Substances 0.000 claims 18
- 230000003321 amplification Effects 0.000 claims 17
- 238000003199 nucleic acid amplification method Methods 0.000 claims 17
- 238000000034 method Methods 0.000 claims 16
- 238000003556 assay Methods 0.000 claims 13
- 229920000642 polymer Polymers 0.000 claims 13
- 150000003839 salts Chemical class 0.000 claims 11
- 244000005700 microbiome Species 0.000 claims 8
- 239000000090 biomarker Substances 0.000 claims 7
- 238000006243 chemical reaction Methods 0.000 claims 7
- 230000002708 enhancing effect Effects 0.000 claims 7
- 239000000693 micelle Substances 0.000 claims 7
- 239000008280 blood Substances 0.000 claims 6
- 210000004369 blood Anatomy 0.000 claims 6
- 108090000790 Enzymes Proteins 0.000 claims 5
- 102000004190 Enzymes Human genes 0.000 claims 5
- 229940088598 enzyme Drugs 0.000 claims 5
- 239000000126 substance Substances 0.000 claims 5
- 241000894006 Bacteria Species 0.000 claims 4
- 241000195493 Cryptophyta Species 0.000 claims 4
- 229920002307 Dextran Polymers 0.000 claims 4
- 241000233866 Fungi Species 0.000 claims 4
- 241000700605 Viruses Species 0.000 claims 4
- 238000001514 detection method Methods 0.000 claims 4
- 238000011901 isothermal amplification Methods 0.000 claims 4
- -1 polyethylene Polymers 0.000 claims 4
- 229920001223 polyethylene glycol Polymers 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 238000000638 solvent extraction Methods 0.000 claims 4
- 108090001090 Lectins Proteins 0.000 claims 3
- 102000004856 Lectins Human genes 0.000 claims 3
- 108060004795 Methyltransferase Proteins 0.000 claims 3
- 239000011248 coating agent Substances 0.000 claims 3
- 238000000576 coating method Methods 0.000 claims 3
- 230000001419 dependent effect Effects 0.000 claims 3
- 230000002209 hydrophobic effect Effects 0.000 claims 3
- 239000002523 lectin Substances 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- 239000000758 substrate Substances 0.000 claims 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 239000004743 Polypropylene Substances 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000002131 composite material Substances 0.000 claims 2
- 238000006073 displacement reaction Methods 0.000 claims 2
- 229910052751 metal Inorganic materials 0.000 claims 2
- 239000002184 metal Substances 0.000 claims 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 2
- 238000003752 polymerase chain reaction Methods 0.000 claims 2
- 229920001451 polypropylene glycol Polymers 0.000 claims 2
- 235000000346 sugar Nutrition 0.000 claims 2
- 150000008163 sugars Chemical class 0.000 claims 2
- 238000013518 transcription Methods 0.000 claims 2
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- 102000002260 Alkaline Phosphatase Human genes 0.000 claims 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 claims 1
- 108091023037 Aptamer Proteins 0.000 claims 1
- 235000011330 Armoracia rusticana Nutrition 0.000 claims 1
- 240000003291 Armoracia rusticana Species 0.000 claims 1
- 229910052684 Cerium Inorganic materials 0.000 claims 1
- 229920002101 Chitin Polymers 0.000 claims 1
- 108010015776 Glucose oxidase Proteins 0.000 claims 1
- 239000004366 Glucose oxidase Substances 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 238000007397 LAMP assay Methods 0.000 claims 1
- 239000004677 Nylon Substances 0.000 claims 1
- 229930040373 Paraformaldehyde Natural products 0.000 claims 1
- 102000003992 Peroxidases Human genes 0.000 claims 1
- 239000004698 Polyethylene Substances 0.000 claims 1
- 102000018120 Recombinases Human genes 0.000 claims 1
- 108010091086 Recombinases Proteins 0.000 claims 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims 1
- 239000002250 absorbent Substances 0.000 claims 1
- 230000002745 absorbent Effects 0.000 claims 1
- 229920001222 biopolymer Polymers 0.000 claims 1
- 239000013592 cell lysate Substances 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 239000000919 ceramic Substances 0.000 claims 1
- GWXLDORMOJMVQZ-UHFFFAOYSA-N cerium Chemical compound [Ce] GWXLDORMOJMVQZ-UHFFFAOYSA-N 0.000 claims 1
- 125000004122 cyclic group Chemical group 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 239000011521 glass Substances 0.000 claims 1
- 229940116332 glucose oxidase Drugs 0.000 claims 1
- 235000019420 glucose oxidase Nutrition 0.000 claims 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims 1
- 229910052737 gold Inorganic materials 0.000 claims 1
- 239000010931 gold Substances 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 229910052742 iron Inorganic materials 0.000 claims 1
- 238000002032 lab-on-a-chip Methods 0.000 claims 1
- 230000002934 lysing effect Effects 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 150000002739 metals Chemical class 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 229920001778 nylon Polymers 0.000 claims 1
- 229910052763 palladium Inorganic materials 0.000 claims 1
- 108040007629 peroxidase activity proteins Proteins 0.000 claims 1
- 239000004033 plastic Substances 0.000 claims 1
- 229920003023 plastic Polymers 0.000 claims 1
- 229910052697 platinum Inorganic materials 0.000 claims 1
- 229920000573 polyethylene Polymers 0.000 claims 1
- 229920006324 polyoxymethylene Polymers 0.000 claims 1
- 229920001155 polypropylene Polymers 0.000 claims 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims 1
- 239000004810 polytetrafluoroethylene Substances 0.000 claims 1
- 229920000915 polyvinyl chloride Polymers 0.000 claims 1
- 239000004800 polyvinyl chloride Substances 0.000 claims 1
- 239000010453 quartz Substances 0.000 claims 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 1
- 229910052709 silver Inorganic materials 0.000 claims 1
- 239000004332 silver Substances 0.000 claims 1
- 229920001059 synthetic polymer Polymers 0.000 claims 1
- 229910052719 titanium Inorganic materials 0.000 claims 1
- 239000010936 titanium Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662348038P | 2016-06-09 | 2016-06-09 | |
| US62/348,038 | 2016-06-09 | ||
| PCT/US2017/036418 WO2017214315A1 (en) | 2016-06-09 | 2017-06-07 | Biomarker concentration and signal amplification for use in paper-based immunoassays and a single platform for extracting, concentrating, and amplifying dna |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019525136A JP2019525136A (ja) | 2019-09-05 |
| JP2019525136A5 true JP2019525136A5 (cg-RX-API-DMAC7.html) | 2020-07-27 |
| JP7320951B2 JP7320951B2 (ja) | 2023-08-04 |
Family
ID=60578148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018564267A Active JP7320951B2 (ja) | 2016-06-09 | 2017-06-07 | ペーパーベースのイムノアッセイにおいて使用するためのバイオマーカー濃縮及びシグナル増幅、ならびにｄｎａを抽出、濃縮、及び増幅するための単一プラットフォーム |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11828755B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP4202439B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP7320951B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102592388B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN116083539A (cg-RX-API-DMAC7.html) |
| AU (2) | AU2017277631B2 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2939842T3 (cg-RX-API-DMAC7.html) |
| PL (1) | PL3469365T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017214315A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102630880B1 (ko) | 2014-03-07 | 2024-01-29 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 분석물 추출, 농축 및 검출을 통합하기 위한 장치 |
| CN108139402B (zh) | 2015-09-04 | 2022-10-18 | 加利福尼亚大学董事会 | 用于临床应用的分析物收集、提取、浓缩和检测的方法和装置 |
| EP4202439B1 (en) | 2016-06-09 | 2025-02-19 | The Regents of the University of California | Method of purifying and amplifying a nucleic acid |
| WO2018039139A1 (en) | 2016-08-22 | 2018-03-01 | The Regents Of The University Of California | Hydrogel platform for aqueous two-phase concentration of a target to enhance its detection |
| US11209427B2 (en) | 2017-03-27 | 2021-12-28 | The Regents Of The University Of California | Semi-quantitative lateral-flow immunoassay for the detection of CSF leaks |
| TW201840854A (zh) * | 2017-03-28 | 2018-11-16 | 彥燾 招 | 準確診斷牙科疾病的方法與設備 |
| EP4234710A3 (en) | 2017-03-28 | 2023-11-01 | Phase Scientific International, Ltd. | Method for accurate diagnosis of a disease targeting biomarkers in liquid biopsy |
| CN114632349B (zh) | 2017-06-01 | 2024-12-17 | 相达生物科技美国有限公司 | 用于多孔材料中双水相分离的相分离行为改性剂 |
| WO2019046563A1 (en) | 2017-09-01 | 2019-03-07 | Phase Diagnostics, Inc. | METHOD AND DEVICE FOR USING AQUEOUS BIPHASE SYSTEMS (ATPS) TO IMPROVE THE DIAGNOSIS OF SEXUALLY TRANSMITTED INFECTIONS |
| EP3684948B1 (en) | 2017-09-18 | 2023-09-06 | Phase Scientific International, Ltd. | Method for using aqueous two-phase system for the isolation, purification and/or concentration of short nucleic acid fragments |
| US12043826B2 (en) | 2018-01-19 | 2024-07-23 | Phase Scientific International, Ltd. | Spontaneous nucleic acid purification and concentration in a single step |
| US11643646B2 (en) | 2018-01-19 | 2023-05-09 | Phase Scientific International, Ltd. | Method for isolating and purifying nucleic acids using a solid-liquid phase system |
| CN108896506B (zh) * | 2018-07-16 | 2020-10-27 | 济南大学 | 检测碱性磷酸酶活性以及碱性磷酸酶抑制剂浓度的方法 |
| CN110205236A (zh) * | 2019-06-12 | 2019-09-06 | 中国检验检疫科学研究院 | 一种基于rpa技术快速检测核酸的纸微流控芯片 |
| JP2023535104A (ja) | 2020-03-20 | 2023-08-16 | フェーズ サイエンティフィック インターナショナル リミテッド | リボ核酸を抽出するための組成物及び方法 |
| CN111672544B (zh) * | 2020-06-08 | 2022-03-01 | 江苏师范大学 | 一种基于水两相系统的纸基生化试剂存储方法 |
| JPWO2022075313A1 (cg-RX-API-DMAC7.html) * | 2020-10-06 | 2022-04-14 | ||
| US12383906B2 (en) | 2021-06-14 | 2025-08-12 | University Of Washington | Device and method for detection of pathogens |
| CN113528666B (zh) * | 2021-07-16 | 2023-09-05 | 南京林业大学 | 一种多类型非编码rna检测方法及其在胃癌预警中的应用 |
| CN113791214B (zh) * | 2021-11-15 | 2022-02-22 | 南京黎明生物制品有限公司 | 一种沙眼衣原体抗原检测用增强液及其应用 |
| WO2023147557A2 (en) * | 2022-01-28 | 2023-08-03 | The Johns Hopkins University | Bio-engineered enzymes and uses thereof |
| US20230400459A1 (en) * | 2022-06-09 | 2023-12-14 | Hero Scientific Ltd. | Gargle specimen sampling |
| CN115200954B (zh) * | 2022-06-28 | 2025-05-06 | 珠海大略科技有限公司 | 一种降低唾液粘度的方法及其应用 |
| NL2033124B1 (en) * | 2022-09-23 | 2024-03-29 | Rapidemic B V | Methods and device for multiple-label nucleic acid amplification and detection |
| WO2024093519A1 (en) | 2022-11-02 | 2024-05-10 | Phase Scientific International, Ltd. | Methods for isolating target analytes from biological samples using atps and solid phase media |
Family Cites Families (87)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
| US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| JPS6412935A (en) | 1987-07-02 | 1989-01-17 | Mitsubishi Electric Corp | Constant-speed travel device for vehicle |
| US5216141A (en) | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
| CA2020029A1 (en) | 1989-07-12 | 1991-01-13 | Yatin B. Thakore | Device and method for separation of plasma from blood and determination of blood analytes |
| US5141850A (en) | 1990-02-07 | 1992-08-25 | Hygeia Sciences, Inc. | Porous strip form assay device method |
| US5386023A (en) | 1990-07-27 | 1995-01-31 | Isis Pharmaceuticals | Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling |
| US5602240A (en) | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| US5644048A (en) | 1992-01-10 | 1997-07-01 | Isis Pharmaceuticals, Inc. | Process for preparing phosphorothioate oligonucleotides |
| US5733743A (en) | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| US5637684A (en) | 1994-02-23 | 1997-06-10 | Isis Pharmaceuticals, Inc. | Phosphoramidate and phosphorothioamidate oligomeric compounds |
| US5710005A (en) | 1996-10-29 | 1998-01-20 | Biocode, Inc. | Analyte detection with a gradient lateral flow device |
| US6194221B1 (en) | 1996-11-19 | 2001-02-27 | Wyntek Diagnostics, Inc. | Hybrid one-step immunochromatographic device and method of use |
| US6979576B1 (en) | 1997-07-25 | 2005-12-27 | Shu-Ching Cheng | Methods of use of one step immunochromatographic device for Streptococcus A antigen |
| US6924153B1 (en) | 1997-03-06 | 2005-08-02 | Quidel Corporation | Quantitative lateral flow assays and devices |
| WO1999047930A1 (en) | 1998-03-16 | 1999-09-23 | Quidel Corporation | Immunoassay device and method |
| US6743605B1 (en) | 1998-06-24 | 2004-06-01 | Enzo Life Sciences, Inc. | Linear amplification of specific nucleic acid sequences |
| US7390675B2 (en) | 1999-10-15 | 2008-06-24 | Christopher Feistel | Multi-functional and configurable assay |
| DK1340085T3 (da) | 2000-10-17 | 2008-12-01 | Besst Test Aps | Assay til direkte detektion af en biologisk celle i en legemsvæskepröve |
| US6855561B2 (en) | 2001-09-10 | 2005-02-15 | Quidel Corporation | Method for adding an apparent non-signal line to a lateral flow assay |
| US20030215358A1 (en) | 2002-01-15 | 2003-11-20 | Schulman Lloyd S. | Liquid permeable composition in dry reagent devices |
| JP3797480B2 (ja) | 2002-03-04 | 2006-07-19 | 株式会社東北テクノアーチ | ネコ腎臓病診断マーカー |
| WO2003105899A1 (en) | 2002-06-13 | 2003-12-24 | Neuropro Technologies, Inc. | Apparatus and methods for detecting cerebrospinal fluid |
| US7244394B2 (en) | 2002-10-03 | 2007-07-17 | Novartis Ag | Methods and kits for assays of analytes of interest in tears |
| US7459314B2 (en) | 2003-02-13 | 2008-12-02 | Inverness Medical Switzerland Gmbh | Lateral flow immunoassay controls |
| WO2004081528A2 (en) | 2003-03-10 | 2004-09-23 | Robinson Joseph R | Assay device and method |
| US20070003992A1 (en) | 2003-04-09 | 2007-01-04 | Pentyala Srinivas N | Methods and kits for detecting cerebrospinal fluid in a sample |
| US8003765B2 (en) | 2003-04-09 | 2011-08-23 | Stony Brook Anaesthesiology, University Faculty Practice Corporation | Methods, antibodies and kits for detecting cerebrospinal fluid in a sample |
| US20040203079A1 (en) | 2003-04-09 | 2004-10-14 | Research Foundation Of The State University Of New York | Methods and kits for detecting cerebrospinal fluid in a sample |
| JPWO2005042579A1 (ja) | 2003-10-31 | 2008-01-10 | 富士レビオ株式会社 | 抗ｓａｒｓウイルス抗体、該抗体を産生するハイブリドーマ及び該抗体を用いる免疫測定試薬 |
| WO2005075998A1 (en) | 2004-01-29 | 2005-08-18 | Dsm Ip Assets B.V. | Improved lateral flow binding assay |
| US7435577B2 (en) | 2004-02-03 | 2008-10-14 | Polymer Technology Systems, Inc. | Direct measurement of chlolesterol from low density lipoprotein with test strip |
| US7867780B2 (en) | 2004-03-30 | 2011-01-11 | Whatman, Inc. | Lateral flow format, materials and methods |
| DE502004005503D1 (de) | 2004-06-25 | 2007-12-27 | Kuehni Ag | Verfahren zur Extraktion von biologischem Material |
| US20060019406A1 (en) | 2004-07-23 | 2006-01-26 | Ning Wei | Lateral flow device for the detection of large pathogens |
| US8445293B2 (en) | 2005-02-09 | 2013-05-21 | Rapid Pathogen Screening, Inc. | Method to increase specificity and/or accuracy of lateral flow immunoassays |
| US20060246513A1 (en) | 2005-05-02 | 2006-11-02 | Bohannon Robert C | Method and device to detect the presence of analytes in a sample |
| MX2007014476A (es) | 2005-05-20 | 2008-02-07 | Calypte Biomedical Corp | Prueba de inmunocromatografia rapida de fluido oral. |
| US7794656B2 (en) | 2006-01-23 | 2010-09-14 | Quidel Corporation | Device for handling and analysis of a biological sample |
| WO2007092302A2 (en) | 2006-02-07 | 2007-08-16 | Envirologix Inc. | Test device for analyte detection |
| EP2215450B1 (en) | 2006-02-21 | 2013-07-31 | Nexus DX, Inc. | Methods and compositions for analyte detection |
| US20090110601A1 (en) | 2006-07-09 | 2009-04-30 | Raphael Levi | Molecularly imprinted polymers for detection in lateral flow devices |
| WO2008043040A2 (en) | 2006-10-05 | 2008-04-10 | Massachusetts Institute Of Technology | Integrated microfluidic device for preconcentration and detection of multiple biomarkers |
| CN101578520B (zh) | 2006-10-18 | 2015-09-16 | 哈佛学院院长等 | 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法 |
| BRPI0718473A2 (pt) | 2006-10-18 | 2013-12-03 | Harvard College | Bioensaio de fluxo direto e fluxo lateral baseado em meio poroso modelado, métodos de produção do mesmo, e métodos de uso do mesmo. |
| US20080138842A1 (en) | 2006-12-11 | 2008-06-12 | Hans Boehringer | Indirect lateral flow sandwich assay |
| KR100902093B1 (ko) | 2007-05-23 | 2009-06-09 | 인하대학교 산학협력단 | 미세채널 내에서 가시광선의 투과도 측정을 이용한 액체의Ｄｒｏｐｌｅｔ／Ｐｌｕｇ 및 미세입자 크기와 개수측정장치 및 측정방법 |
| US20100227323A1 (en) | 2007-07-30 | 2010-09-09 | Cornell Research Foundation, Inc. | Microchannel detection device and use thereof |
| CN101945990A (zh) | 2007-12-27 | 2011-01-12 | 尹菲戈诊断有限公司 | 基于分子印记聚合物的小分子和蛋白质分析装置 |
| AU2009228091B2 (en) | 2008-03-27 | 2015-05-21 | President And Fellows Of Harvard College | Three-dimensional microfluidic devices |
| EP2279403B1 (en) | 2008-05-05 | 2016-03-16 | Los Alamos National Security, LLC | Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control |
| US20130196310A1 (en) | 2008-05-20 | 2013-08-01 | Rapid Pathogen Screening, Inc. | Method and Device for Combined Detection of Viral and Bacterial Infections |
| WO2010027812A2 (en) | 2008-08-25 | 2010-03-11 | University Of Washington | Microfluidic systems incorporating flow-through membranes |
| KR101761426B1 (ko) | 2009-04-28 | 2017-07-25 | 덴카 세이켄 가부시키가이샤 | 간이 멤브레인 어세이 장치 |
| BR112012002748A2 (pt) | 2009-08-07 | 2016-11-01 | Affinimark Technologies Inc | dispositivo e método para a identificação imunológica do líquido cerebrospinal |
| JP5205354B2 (ja) | 2009-09-30 | 2013-06-05 | 富士フイルム株式会社 | クロマトグラフ測定装置 |
| WO2011116256A2 (en) | 2010-03-18 | 2011-09-22 | The Regents Of The University Of Michigan | Multiphase microarrays and uses thereof |
| WO2011159537A2 (en) * | 2010-06-15 | 2011-12-22 | The Regents Of The University Of California | Method and device for analyte detection |
| US20110312557A1 (en) | 2010-06-17 | 2011-12-22 | Geneasys Pty Ltd | Loc device for pathogen detection with dialysis, lysis and parallel nucleic acid amplification |
| FR2963108B1 (fr) | 2010-07-21 | 2017-06-23 | Diagast | Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin |
| WO2012125781A2 (en) | 2011-03-15 | 2012-09-20 | Colorado State University Research Foundation | Rapid detection of pathogens using paper devices |
| DE102011001743A1 (de) | 2011-04-01 | 2012-10-04 | Technische Universität Dortmund | Verfahren zur Trennung/Reinigung von Biomolekühlen |
| US9493736B2 (en) * | 2011-04-27 | 2016-11-15 | Merck Patent Gmbh | Method for lysing cells |
| US9939442B2 (en) | 2011-09-08 | 2018-04-10 | The Regents Of The University Of California | Salivary biomarkers for gastric cancer detection |
| EP2761304A4 (en) | 2011-09-30 | 2015-01-28 | Univ California | MICROFLUIDIC APPARATUS AND METHOD FOR EXAMINING A LIQUID SAMPLE THEREWITH |
| JP6215223B2 (ja) | 2011-12-09 | 2017-10-18 | アンスティテュ・パストゥール | マルチプレックス免疫スクリーニングアッセイ |
| WO2013105090A1 (en) | 2012-01-11 | 2013-07-18 | Aptateck Bio Ltd. | A versatile lateral flow strip device |
| JP5917201B2 (ja) | 2012-03-02 | 2016-05-11 | 田中貴金属工業株式会社 | イムノクロマトグラフィー用試験ストリップ |
| US20140004539A1 (en) | 2012-06-15 | 2014-01-02 | The Regents Of The University Of Michigan | Systems and methods for multiplex solution assays |
| US9310300B2 (en) | 2012-08-03 | 2016-04-12 | Ingeneron Incorporated | Compact portable apparatus for optical assay |
| US20160282343A1 (en) | 2012-08-15 | 2016-09-29 | Immunolab LLC | Quantitative lateral flow assay strips for quantitative analysis of an analyte, kits containing such strips and methods of manufacture and use of same |
| US20150198592A1 (en) | 2012-11-15 | 2015-07-16 | Daniel Wang | Rapid Lateral Flow Assay Method for Low Quantity Liquid or Dry Samples |
| US20150017656A1 (en) | 2012-11-15 | 2015-01-15 | Daniel Wang | Rapid Lateral Flow Assay Method for Detecting Low Quantity Liquid or Dry Samples |
| CN104955962B (zh) * | 2012-12-18 | 2017-10-03 | 凯杰有限公司 | 核酸扩增方法 |
| CN103808926B (zh) | 2014-01-14 | 2016-08-17 | 中国科学院生物物理研究所 | 纳米模拟酶免疫层析检测方法 |
| KR102630880B1 (ko) * | 2014-03-07 | 2024-01-29 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 분석물 추출, 농축 및 검출을 통합하기 위한 장치 |
| US20160313307A1 (en) | 2015-04-23 | 2016-10-27 | Ted Titmus | Diagnostic test strip for oral samples and method of use therefore |
| CN108139402B (zh) | 2015-09-04 | 2022-10-18 | 加利福尼亚大学董事会 | 用于临床应用的分析物收集、提取、浓缩和检测的方法和装置 |
| US20170323441A1 (en) | 2016-05-09 | 2017-11-09 | University Of Washington | Filter-free devices and systems for measuring fluorescence of a microfluidic assay and associated methods of use |
| EP4202439B1 (en) | 2016-06-09 | 2025-02-19 | The Regents of the University of California | Method of purifying and amplifying a nucleic acid |
| US11761958B2 (en) | 2016-07-12 | 2023-09-19 | Purdue Research Foundation | Devices, systems, and methods for the detection of a target analyte using magnetic focus lateral flow immunoassay techniques |
| WO2018039139A1 (en) | 2016-08-22 | 2018-03-01 | The Regents Of The University Of California | Hydrogel platform for aqueous two-phase concentration of a target to enhance its detection |
| US11209427B2 (en) | 2017-03-27 | 2021-12-28 | The Regents Of The University Of California | Semi-quantitative lateral-flow immunoassay for the detection of CSF leaks |
| WO2018222765A1 (en) | 2017-05-31 | 2018-12-06 | The Regents Of The University Of California | Single-step atps enhanced lfa diagnostic design |
-
2017
- 2017-06-07 EP EP22211678.2A patent/EP4202439B1/en active Active
- 2017-06-07 AU AU2017277631A patent/AU2017277631B2/en active Active
- 2017-06-07 US US16/307,125 patent/US11828755B2/en active Active
- 2017-06-07 PL PL17810966.6T patent/PL3469365T3/pl unknown
- 2017-06-07 CN CN202310306917.3A patent/CN116083539A/zh active Pending
- 2017-06-07 CN CN201780046652.0A patent/CN109477133B/zh active Active
- 2017-06-07 WO PCT/US2017/036418 patent/WO2017214315A1/en not_active Ceased
- 2017-06-07 KR KR1020197000413A patent/KR102592388B1/ko active Active
- 2017-06-07 EP EP17810966.6A patent/EP3469365B1/en active Active
- 2017-06-07 JP JP2018564267A patent/JP7320951B2/ja active Active
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