PL3469365T3 - Zatężanie biomarkera i amplifikacja sygnału do zastosowania w testach immunologicznych na bazie papieru - Google Patents

Zatężanie biomarkera i amplifikacja sygnału do zastosowania w testach immunologicznych na bazie papieru

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Publication number
PL3469365T3
PL3469365T3 PL17810966.6T PL17810966T PL3469365T3 PL 3469365 T3 PL3469365 T3 PL 3469365T3 PL 17810966 T PL17810966 T PL 17810966T PL 3469365 T3 PL3469365 T3 PL 3469365T3
Authority
PL
Poland
Prior art keywords
paper
signal amplification
biomarker concentration
based immunoassays
immunoassays
Prior art date
Application number
PL17810966.6T
Other languages
English (en)
Polish (pl)
Inventor
Daniel Takashi KAMEI
Benjamin Ming WU
Daniel William BRADBURY
Shin Ting Sherine Frieda CHEUNG
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of PL3469365T3 publication Critical patent/PL3469365T3/pl

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/5432—Liposomes or microcapsules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/625—Detection means characterised by use of a special device being a nucleic acid test strip device, e.g. dipsticks, strips, tapes, CD plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/631—Detection means characterised by use of a special device being a biochannel or pore

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
PL17810966.6T 2016-06-09 2017-06-07 Zatężanie biomarkera i amplifikacja sygnału do zastosowania w testach immunologicznych na bazie papieru PL3469365T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662348038P 2016-06-09 2016-06-09
PCT/US2017/036418 WO2017214315A1 (en) 2016-06-09 2017-06-07 Biomarker concentration and signal amplification for use in paper-based immunoassays and a single platform for extracting, concentrating, and amplifying dna

Publications (1)

Publication Number Publication Date
PL3469365T3 true PL3469365T3 (pl) 2023-04-03

Family

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Family Applications (1)

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PL17810966.6T PL3469365T3 (pl) 2016-06-09 2017-06-07 Zatężanie biomarkera i amplifikacja sygnału do zastosowania w testach immunologicznych na bazie papieru

Country Status (9)

Country Link
US (1) US11828755B2 (cg-RX-API-DMAC7.html)
EP (2) EP4202439B1 (cg-RX-API-DMAC7.html)
JP (1) JP7320951B2 (cg-RX-API-DMAC7.html)
KR (1) KR102592388B1 (cg-RX-API-DMAC7.html)
CN (2) CN116083539A (cg-RX-API-DMAC7.html)
AU (2) AU2017277631B2 (cg-RX-API-DMAC7.html)
ES (1) ES2939842T3 (cg-RX-API-DMAC7.html)
PL (1) PL3469365T3 (cg-RX-API-DMAC7.html)
WO (1) WO2017214315A1 (cg-RX-API-DMAC7.html)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102630880B1 (ko) 2014-03-07 2024-01-29 더 리전트 오브 더 유니버시티 오브 캘리포니아 분석물 추출, 농축 및 검출을 통합하기 위한 장치
CN108139402B (zh) 2015-09-04 2022-10-18 加利福尼亚大学董事会 用于临床应用的分析物收集、提取、浓缩和检测的方法和装置
EP4202439B1 (en) 2016-06-09 2025-02-19 The Regents of the University of California Method of purifying and amplifying a nucleic acid
WO2018039139A1 (en) 2016-08-22 2018-03-01 The Regents Of The University Of California Hydrogel platform for aqueous two-phase concentration of a target to enhance its detection
US11209427B2 (en) 2017-03-27 2021-12-28 The Regents Of The University Of California Semi-quantitative lateral-flow immunoassay for the detection of CSF leaks
TW201840854A (zh) * 2017-03-28 2018-11-16 彥燾 招 準確診斷牙科疾病的方法與設備
EP4234710A3 (en) 2017-03-28 2023-11-01 Phase Scientific International, Ltd. Method for accurate diagnosis of a disease targeting biomarkers in liquid biopsy
CN114632349B (zh) 2017-06-01 2024-12-17 相达生物科技美国有限公司 用于多孔材料中双水相分离的相分离行为改性剂
WO2019046563A1 (en) 2017-09-01 2019-03-07 Phase Diagnostics, Inc. METHOD AND DEVICE FOR USING AQUEOUS BIPHASE SYSTEMS (ATPS) TO IMPROVE THE DIAGNOSIS OF SEXUALLY TRANSMITTED INFECTIONS
EP3684948B1 (en) 2017-09-18 2023-09-06 Phase Scientific International, Ltd. Method for using aqueous two-phase system for the isolation, purification and/or concentration of short nucleic acid fragments
US12043826B2 (en) 2018-01-19 2024-07-23 Phase Scientific International, Ltd. Spontaneous nucleic acid purification and concentration in a single step
US11643646B2 (en) 2018-01-19 2023-05-09 Phase Scientific International, Ltd. Method for isolating and purifying nucleic acids using a solid-liquid phase system
CN108896506B (zh) * 2018-07-16 2020-10-27 济南大学 检测碱性磷酸酶活性以及碱性磷酸酶抑制剂浓度的方法
CN110205236A (zh) * 2019-06-12 2019-09-06 中国检验检疫科学研究院 一种基于rpa技术快速检测核酸的纸微流控芯片
JP2023535104A (ja) 2020-03-20 2023-08-16 フェーズ サイエンティフィック インターナショナル リミテッド リボ核酸を抽出するための組成物及び方法
CN111672544B (zh) * 2020-06-08 2022-03-01 江苏师范大学 一种基于水两相系统的纸基生化试剂存储方法
JPWO2022075313A1 (cg-RX-API-DMAC7.html) * 2020-10-06 2022-04-14
US12383906B2 (en) 2021-06-14 2025-08-12 University Of Washington Device and method for detection of pathogens
CN113528666B (zh) * 2021-07-16 2023-09-05 南京林业大学 一种多类型非编码rna检测方法及其在胃癌预警中的应用
CN113791214B (zh) * 2021-11-15 2022-02-22 南京黎明生物制品有限公司 一种沙眼衣原体抗原检测用增强液及其应用
WO2023147557A2 (en) * 2022-01-28 2023-08-03 The Johns Hopkins University Bio-engineered enzymes and uses thereof
US20230400459A1 (en) * 2022-06-09 2023-12-14 Hero Scientific Ltd. Gargle specimen sampling
CN115200954B (zh) * 2022-06-28 2025-05-06 珠海大略科技有限公司 一种降低唾液粘度的方法及其应用
NL2033124B1 (en) * 2022-09-23 2024-03-29 Rapidemic B V Methods and device for multiple-label nucleic acid amplification and detection
WO2024093519A1 (en) 2022-11-02 2024-05-10 Phase Scientific International, Ltd. Methods for isolating target analytes from biological samples using atps and solid phase media

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4469863A (en) 1980-11-12 1984-09-04 Ts O Paul O P Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5235033A (en) 1985-03-15 1993-08-10 Anti-Gene Development Group Alpha-morpholino ribonucleoside derivatives and polymers thereof
US5132405A (en) 1987-05-21 1992-07-21 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5091513A (en) 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
JPS6412935A (en) 1987-07-02 1989-01-17 Mitsubishi Electric Corp Constant-speed travel device for vehicle
US5216141A (en) 1988-06-06 1993-06-01 Benner Steven A Oligonucleotide analogs containing sulfur linkages
CA2020029A1 (en) 1989-07-12 1991-01-13 Yatin B. Thakore Device and method for separation of plasma from blood and determination of blood analytes
US5141850A (en) 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method
US5386023A (en) 1990-07-27 1995-01-31 Isis Pharmaceuticals Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
US5602240A (en) 1990-07-27 1997-02-11 Ciba Geigy Ag. Backbone modified oligonucleotide analogs
US5644048A (en) 1992-01-10 1997-07-01 Isis Pharmaceuticals, Inc. Process for preparing phosphorothioate oligonucleotides
US5733743A (en) 1992-03-24 1998-03-31 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
US5637684A (en) 1994-02-23 1997-06-10 Isis Pharmaceuticals, Inc. Phosphoramidate and phosphorothioamidate oligomeric compounds
US5710005A (en) 1996-10-29 1998-01-20 Biocode, Inc. Analyte detection with a gradient lateral flow device
US6194221B1 (en) 1996-11-19 2001-02-27 Wyntek Diagnostics, Inc. Hybrid one-step immunochromatographic device and method of use
US6979576B1 (en) 1997-07-25 2005-12-27 Shu-Ching Cheng Methods of use of one step immunochromatographic device for Streptococcus A antigen
US6924153B1 (en) 1997-03-06 2005-08-02 Quidel Corporation Quantitative lateral flow assays and devices
WO1999047930A1 (en) 1998-03-16 1999-09-23 Quidel Corporation Immunoassay device and method
US6743605B1 (en) 1998-06-24 2004-06-01 Enzo Life Sciences, Inc. Linear amplification of specific nucleic acid sequences
US7390675B2 (en) 1999-10-15 2008-06-24 Christopher Feistel Multi-functional and configurable assay
DK1340085T3 (da) 2000-10-17 2008-12-01 Besst Test Aps Assay til direkte detektion af en biologisk celle i en legemsvæskepröve
US6855561B2 (en) 2001-09-10 2005-02-15 Quidel Corporation Method for adding an apparent non-signal line to a lateral flow assay
US20030215358A1 (en) 2002-01-15 2003-11-20 Schulman Lloyd S. Liquid permeable composition in dry reagent devices
JP3797480B2 (ja) 2002-03-04 2006-07-19 株式会社東北テクノアーチ ネコ腎臓病診断マーカー
WO2003105899A1 (en) 2002-06-13 2003-12-24 Neuropro Technologies, Inc. Apparatus and methods for detecting cerebrospinal fluid
US7244394B2 (en) 2002-10-03 2007-07-17 Novartis Ag Methods and kits for assays of analytes of interest in tears
US7459314B2 (en) 2003-02-13 2008-12-02 Inverness Medical Switzerland Gmbh Lateral flow immunoassay controls
WO2004081528A2 (en) 2003-03-10 2004-09-23 Robinson Joseph R Assay device and method
US20070003992A1 (en) 2003-04-09 2007-01-04 Pentyala Srinivas N Methods and kits for detecting cerebrospinal fluid in a sample
US8003765B2 (en) 2003-04-09 2011-08-23 Stony Brook Anaesthesiology, University Faculty Practice Corporation Methods, antibodies and kits for detecting cerebrospinal fluid in a sample
US20040203079A1 (en) 2003-04-09 2004-10-14 Research Foundation Of The State University Of New York Methods and kits for detecting cerebrospinal fluid in a sample
JPWO2005042579A1 (ja) 2003-10-31 2008-01-10 富士レビオ株式会社 抗ｓａｒｓウイルス抗体、該抗体を産生するハイブリドーマ及び該抗体を用いる免疫測定試薬
WO2005075998A1 (en) 2004-01-29 2005-08-18 Dsm Ip Assets B.V. Improved lateral flow binding assay
US7435577B2 (en) 2004-02-03 2008-10-14 Polymer Technology Systems, Inc. Direct measurement of chlolesterol from low density lipoprotein with test strip
US7867780B2 (en) 2004-03-30 2011-01-11 Whatman, Inc. Lateral flow format, materials and methods
DE502004005503D1 (de) 2004-06-25 2007-12-27 Kuehni Ag Verfahren zur Extraktion von biologischem Material
US20060019406A1 (en) 2004-07-23 2006-01-26 Ning Wei Lateral flow device for the detection of large pathogens
US8445293B2 (en) 2005-02-09 2013-05-21 Rapid Pathogen Screening, Inc. Method to increase specificity and/or accuracy of lateral flow immunoassays
US20060246513A1 (en) 2005-05-02 2006-11-02 Bohannon Robert C Method and device to detect the presence of analytes in a sample
MX2007014476A (es) 2005-05-20 2008-02-07 Calypte Biomedical Corp Prueba de inmunocromatografia rapida de fluido oral.
US7794656B2 (en) 2006-01-23 2010-09-14 Quidel Corporation Device for handling and analysis of a biological sample
WO2007092302A2 (en) 2006-02-07 2007-08-16 Envirologix Inc. Test device for analyte detection
EP2215450B1 (en) 2006-02-21 2013-07-31 Nexus DX, Inc. Methods and compositions for analyte detection
US20090110601A1 (en) 2006-07-09 2009-04-30 Raphael Levi Molecularly imprinted polymers for detection in lateral flow devices
WO2008043040A2 (en) 2006-10-05 2008-04-10 Massachusetts Institute Of Technology Integrated microfluidic device for preconcentration and detection of multiple biomarkers
CN101578520B (zh) 2006-10-18 2015-09-16 哈佛学院院长等 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法
BRPI0718473A2 (pt) 2006-10-18 2013-12-03 Harvard College Bioensaio de fluxo direto e fluxo lateral baseado em meio poroso modelado, métodos de produção do mesmo, e métodos de uso do mesmo.
US20080138842A1 (en) 2006-12-11 2008-06-12 Hans Boehringer Indirect lateral flow sandwich assay
KR100902093B1 (ko) 2007-05-23 2009-06-09 인하대학교 산학협력단 미세채널 내에서 가시광선의 투과도 측정을 이용한 액체의Ｄｒｏｐｌｅｔ／Ｐｌｕｇ 및 미세입자 크기와 개수측정장치 및 측정방법
US20100227323A1 (en) 2007-07-30 2010-09-09 Cornell Research Foundation, Inc. Microchannel detection device and use thereof
CN101945990A (zh) 2007-12-27 2011-01-12 尹菲戈诊断有限公司 基于分子印记聚合物的小分子和蛋白质分析装置
AU2009228091B2 (en) 2008-03-27 2015-05-21 President And Fellows Of Harvard College Three-dimensional microfluidic devices
EP2279403B1 (en) 2008-05-05 2016-03-16 Los Alamos National Security, LLC Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control
US20130196310A1 (en) 2008-05-20 2013-08-01 Rapid Pathogen Screening, Inc. Method and Device for Combined Detection of Viral and Bacterial Infections
WO2010027812A2 (en) 2008-08-25 2010-03-11 University Of Washington Microfluidic systems incorporating flow-through membranes
KR101761426B1 (ko) 2009-04-28 2017-07-25 덴카 세이켄 가부시키가이샤 간이 멤브레인 어세이 장치
BR112012002748A2 (pt) 2009-08-07 2016-11-01 Affinimark Technologies Inc dispositivo e método para a identificação imunológica do líquido cerebrospinal
JP5205354B2 (ja) 2009-09-30 2013-06-05 富士フイルム株式会社 クロマトグラフ測定装置
WO2011116256A2 (en) 2010-03-18 2011-09-22 The Regents Of The University Of Michigan Multiphase microarrays and uses thereof
WO2011159537A2 (en) * 2010-06-15 2011-12-22 The Regents Of The University Of California Method and device for analyte detection
US20110312557A1 (en) 2010-06-17 2011-12-22 Geneasys Pty Ltd Loc device for pathogen detection with dialysis, lysis and parallel nucleic acid amplification
FR2963108B1 (fr) 2010-07-21 2017-06-23 Diagast Procede magnetique d'immunodiagnostic et kit pour la mise en evidence de complexe anticorps/antigene de groupe/phenotype sanguin
WO2012125781A2 (en) 2011-03-15 2012-09-20 Colorado State University Research Foundation Rapid detection of pathogens using paper devices
DE102011001743A1 (de) 2011-04-01 2012-10-04 Technische Universität Dortmund Verfahren zur Trennung/Reinigung von Biomolekühlen
US9493736B2 (en) * 2011-04-27 2016-11-15 Merck Patent Gmbh Method for lysing cells
US9939442B2 (en) 2011-09-08 2018-04-10 The Regents Of The University Of California Salivary biomarkers for gastric cancer detection
EP2761304A4 (en) 2011-09-30 2015-01-28 Univ California MICROFLUIDIC APPARATUS AND METHOD FOR EXAMINING A LIQUID SAMPLE THEREWITH
JP6215223B2 (ja) 2011-12-09 2017-10-18 アンスティテュ・パストゥール マルチプレックス免疫スクリーニングアッセイ
WO2013105090A1 (en) 2012-01-11 2013-07-18 Aptateck Bio Ltd. A versatile lateral flow strip device
JP5917201B2 (ja) 2012-03-02 2016-05-11 田中貴金属工業株式会社 イムノクロマトグラフィー用試験ストリップ
US20140004539A1 (en) 2012-06-15 2014-01-02 The Regents Of The University Of Michigan Systems and methods for multiplex solution assays
US9310300B2 (en) 2012-08-03 2016-04-12 Ingeneron Incorporated Compact portable apparatus for optical assay
US20160282343A1 (en) 2012-08-15 2016-09-29 Immunolab LLC Quantitative lateral flow assay strips for quantitative analysis of an analyte, kits containing such strips and methods of manufacture and use of same
US20150198592A1 (en) 2012-11-15 2015-07-16 Daniel Wang Rapid Lateral Flow Assay Method for Low Quantity Liquid or Dry Samples
US20150017656A1 (en) 2012-11-15 2015-01-15 Daniel Wang Rapid Lateral Flow Assay Method for Detecting Low Quantity Liquid or Dry Samples
CN104955962B (zh) * 2012-12-18 2017-10-03 凯杰有限公司 核酸扩增方法
CN103808926B (zh) 2014-01-14 2016-08-17 中国科学院生物物理研究所 纳米模拟酶免疫层析检测方法
KR102630880B1 (ko) * 2014-03-07 2024-01-29 더 리전트 오브 더 유니버시티 오브 캘리포니아 분석물 추출, 농축 및 검출을 통합하기 위한 장치
US20160313307A1 (en) 2015-04-23 2016-10-27 Ted Titmus Diagnostic test strip for oral samples and method of use therefore
CN108139402B (zh) 2015-09-04 2022-10-18 加利福尼亚大学董事会 用于临床应用的分析物收集、提取、浓缩和检测的方法和装置
US20170323441A1 (en) 2016-05-09 2017-11-09 University Of Washington Filter-free devices and systems for measuring fluorescence of a microfluidic assay and associated methods of use
EP4202439B1 (en) 2016-06-09 2025-02-19 The Regents of the University of California Method of purifying and amplifying a nucleic acid
US11761958B2 (en) 2016-07-12 2023-09-19 Purdue Research Foundation Devices, systems, and methods for the detection of a target analyte using magnetic focus lateral flow immunoassay techniques
WO2018039139A1 (en) 2016-08-22 2018-03-01 The Regents Of The University Of California Hydrogel platform for aqueous two-phase concentration of a target to enhance its detection
US11209427B2 (en) 2017-03-27 2021-12-28 The Regents Of The University Of California Semi-quantitative lateral-flow immunoassay for the detection of CSF leaks
WO2018222765A1 (en) 2017-05-31 2018-12-06 The Regents Of The University Of California Single-step atps enhanced lfa diagnostic design

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EP3469365A1 (en) 2019-04-17
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