|
GB1507957A
(en)
|
1975-03-25 |
1978-04-19 |
Byk Gulden Lomberg Chem Fab |
Nitrofuryl-pyrazole derivatives methods for producing them and medicaments comprising them
|
|
US4072746A
(en)
|
1975-10-14 |
1978-02-07 |
Sterling Drug Inc. |
3-Amino-5-(pyridinyl)-2(1H)-pyridinones
|
|
US4004012A
(en)
|
1975-10-14 |
1977-01-18 |
Sterling Drug Inc. |
3-Cyano-5-(pyridinyl)-2(1H)-pyridinones
|
|
DE2845456A1
(de)
|
1978-10-19 |
1980-08-14 |
Merck Patent Gmbh |
6-arylpyridazin-3-one und verfahren zu ihrer herstellung
|
|
US4298609A
(en)
|
1979-08-30 |
1981-11-03 |
Sterling Drug Inc. |
4,5-Dihydro-6-(4-pyridinyl)-3-pyridazinol and salts, their preparation and use as blood pressure lowering agents
|
|
FR2478640A1
(fr)
|
1980-03-24 |
1981-09-25 |
Sanofi Sa |
Nouvelles thieno (2,3-d) pyridazinones-4 et thieno (2,3-d) pyridazinones-7, leur procede de preparation et leur therapeutique
|
|
US4338446A
(en)
|
1980-04-28 |
1982-07-06 |
Sterling Drug Inc. |
Di-(lower-alkyl)hydroxy-[2-oxo-2-(pyridinyl)ethyl]-propanedioates
|
|
US4305943A
(en)
|
1980-04-28 |
1981-12-15 |
Sterling Drug Inc. |
4-Amino-6-(pyridinyl)-3(2H)-pyridazinones and their use as cardiotonics
|
|
US4304776A
(en)
|
1980-04-28 |
1981-12-08 |
Sterling Drug Inc. |
4-Substituted-6-(pyridinyl)-3(2h)-pyridazinones and their use as intermediates and cardiotonics
|
|
US4337253A
(en)
|
1980-04-28 |
1982-06-29 |
Sterling Drug Inc. |
4,5-Dihydro-2-methyl-6-(4-pyridinyl)-3(2H)-pyridazinone and its use as a cardiotonic
|
|
US4486431A
(en)
|
1981-01-14 |
1984-12-04 |
Sterling Drug Inc. |
Cardiotonic use of 4,5-dihydro-6-(4-pyridinyl)-3(2H)-pyridazinones
|
|
US4346221A
(en)
|
1980-04-28 |
1982-08-24 |
Sterling Drug Inc. |
Preparation of 4-amino-6-(pyridinyl)-3(2H)-pyridazinones from 6-(pyridinyl)-3(2H)-pyridazinones
|
|
US4559352A
(en)
|
1981-03-30 |
1985-12-17 |
Sterling Drug Inc. |
1,2-Dihydro-2-oxo-5-(hydroxy-and/or amino-phenyl)-nicotinonitriles and cardiotonic use thereof
|
|
US4404203A
(en)
|
1981-05-14 |
1983-09-13 |
Warner-Lambert Company |
Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
|
|
US4397854A
(en)
|
1981-05-14 |
1983-08-09 |
Warner-Lambert Company |
Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
|
|
US4515797A
(en)
|
1981-09-08 |
1985-05-07 |
Sterling Drug Inc. |
3-Amino-5-(hydroxy- and/or aminophenyl)-6-(lower-alkyl)-2(1H)-pyridinones and cardiotonic use thereof
|
|
US4465686A
(en)
|
1981-09-08 |
1984-08-14 |
Sterling Drug Inc. |
5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation
|
|
US4353905A
(en)
|
1981-09-17 |
1982-10-12 |
Warner-Lambert Company |
Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones
|
|
US4599423A
(en)
|
1982-04-26 |
1986-07-08 |
Sterling Drug Inc. |
Preparation of 5-(hydroxy- and/or aminophenyl-6-lower-alkyl)-2(1H)-pyridinones
|
|
US4734415A
(en)
|
1982-08-13 |
1988-03-29 |
Warner-Lambert Company |
Substituted 4,5-dihydro-6-(substituted)-phenyl-3(2H)-pyridazinones and 6-(substituted) phenyl-3(2H)-pyridazinones
|
|
DE3241102A1
(de)
|
1982-11-06 |
1984-05-10 |
A. Nattermann & Cie GmbH, 5000 Köln |
Imidazolylalkylthienyl-tetrahydropyridazine und verfahren zu ihrer herstellung
|
|
DE3321012A1
(de)
|
1983-06-10 |
1984-12-13 |
A. Nattermann & Cie GmbH, 5000 Köln |
Substituierte 4,5-dihydro-6-(thien-2-yl)-3(2h)-pyridazinone und 6-(thien-2-yl)-3(2h)-pyridazinone sowie verfahren zu ihrer herstellung
|
|
US4666902A
(en)
|
1983-06-20 |
1987-05-19 |
Cassella Aktiengesellschaft |
Tetrahydropyridazinone derivatives, processes for their preparation and their use
|
|
GB8323553D0
(en)
|
1983-09-02 |
1983-10-05 |
Smith Kline French Lab |
Pharmaceutical compositions
|
|
US4816454A
(en)
|
1984-09-21 |
1989-03-28 |
Cassella Aktiengesellschaft |
4,5-dihydro-3(2H)-pyridazinones and their pharmacological use
|
|
US5217735A
(en)
|
1986-10-22 |
1993-06-08 |
Wm. Wrigley Jr. Company |
Method of making chewing gum with delayed release ingredients
|
|
US5221543A
(en)
|
1986-10-22 |
1993-06-22 |
Firma Wilhelm Fette Gmbh |
Method of making a fast release stabilized aspartame ingredient for chewing gum
|
|
US5112625A
(en)
|
1989-02-15 |
1992-05-12 |
Wm. Wrigley Jr. Company |
Aqueous zein coated sweeteners and other ingredients for chewing gum
|
|
US5192563A
(en)
|
1986-10-22 |
1993-03-09 |
Wm. Wrigley, Jr. Company |
Strongly mint-flavored chewing gums with reduced bitterness and harshness
|
|
US4863745A
(en)
|
1986-10-22 |
1989-09-05 |
Wm. Wrigley Jr. Company |
Chewing gum containing zein coated high-potency sweetener and method
|
|
US4908371A
(en)
|
1987-11-10 |
1990-03-13 |
Ciba-Geigy Corporation |
Esterified hydroxy dihydropyridinones for treating diseases associated with trivalent metal ion overload
|
|
US4919941A
(en)
|
1987-12-18 |
1990-04-24 |
Wm. Wrigley Jr. Company |
Chewing gum containing delayed release protein sweetener and method
|
|
DE4134467A1
(de)
|
1991-10-18 |
1993-04-22 |
Thomae Gmbh Dr K |
Heterobiarylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
|
JP3120857B2
(ja)
|
1990-02-19 |
2000-12-25 |
中外製薬株式会社 |
新規な縮合複素環化合物とこれを用いた抗喘息剤
|
|
DE4023369A1
(de)
|
1990-07-23 |
1992-01-30 |
Thomae Gmbh Dr K |
Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
|
DE69131268T2
(de)
|
1990-09-21 |
1999-12-30 |
Rohm And Haas Co., Philadelphia |
Dihydropyridazinone und Pyridazinone als Fungizide
|
|
WO1992006087A1
(en)
|
1990-10-02 |
1992-04-16 |
Kaken Pharmaceutical Co., Ltd. |
Pyridazinone-substituted ethynylphenyl derivative and remedy for circulatory organ disease containing the same as active ingredient
|
|
DE4127404A1
(de)
|
1991-08-19 |
1993-02-25 |
Thomae Gmbh Dr K |
Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
|
CN1038249C
(zh)
|
1991-08-28 |
1998-05-06 |
罗姆和哈斯公司 |
含有二氢哒嗪酮及其相关化合物的杀菌组合物
|
|
ZA927755B
(en)
|
1991-10-09 |
1994-04-08 |
Syntex Inc |
Pyrido pyridazinone and pyridazinthione compounds
|
|
US5716954A
(en)
|
1991-10-09 |
1998-02-10 |
Syntex U.S.A. Inc. |
Benzopyridazinone and pyridopyridazinone compounds
|
|
DE4237656A1
(de)
|
1992-06-13 |
1993-12-16 |
Merck Patent Gmbh |
Benzimidazolderivate
|
|
JPH08502973A
(ja)
|
1992-11-02 |
1996-04-02 |
メルク エンド カンパニー インコーポレーテッド |
ニューロテンシンアンタゴニストとしての置換フタラジノン
|
|
US5814651A
(en)
|
1992-12-02 |
1998-09-29 |
Pfizer Inc. |
Catechol diethers as selective PDEIV inhibitors
|
|
EP0634404A1
(en)
|
1993-07-13 |
1995-01-18 |
Rhone Poulenc Agriculture Ltd. |
Phtalazin derivatives and their use as pesticides
|
|
GB9314412D0
(en)
|
1993-07-13 |
1993-08-25 |
Rhone Poulenc Agriculture |
New compositions of matter
|
|
TW263498B
(enExample)
|
1993-11-10 |
1995-11-21 |
Takeda Pharm Industry Co Ltd |
|
|
JP3247540B2
(ja)
|
1994-05-12 |
2002-01-15 |
株式会社日立製作所 |
パケット化通信装置および切替え装置
|
|
US5466697A
(en)
|
1994-07-13 |
1995-11-14 |
Syntex (U.S.A.) Inc. |
8-phenyl-1,6-naphthyridin-5-ones
|
|
AU691673B2
(en)
|
1994-11-14 |
1998-05-21 |
Dow Agrosciences Llc |
Pyridazinones and their use as fungicides
|
|
JPH08337583A
(ja)
|
1995-04-13 |
1996-12-24 |
Takeda Chem Ind Ltd |
複素環化合物およびその製造法
|
|
US5635494A
(en)
|
1995-04-21 |
1997-06-03 |
Rohm And Haas Company |
Dihydropyridazinones and pyridazinones and their use as fungicides and insecticides
|
|
JPH11508267A
(ja)
|
1995-06-26 |
1999-07-21 |
藤沢薬品工業株式会社 |
ピラゾール化合物および医薬組成物
|
|
IL118631A
(en)
|
1995-06-27 |
2002-05-23 |
Tanabe Seiyaku Co |
History of pyridazinone and processes for their preparation
|
|
AU723064B2
(en)
|
1995-08-25 |
2000-08-17 |
Dow Agrosciences Llc |
Compositions having synergistic fungitoxic effects
|
|
WO1999029695A1
(en)
|
1997-12-05 |
1999-06-17 |
Astrazeneca Uk Limited |
Novel compounds
|
|
CN1109037C
(zh)
|
1996-09-13 |
2003-05-21 |
三菱制药株式会社 |
噻吩并-三唑并二氮杂䓬化合物及其医药用途
|
|
US5855654A
(en)
|
1997-01-30 |
1999-01-05 |
Rohm And Haas Company |
Pyridazinones as marine antifouling agents
|
|
DK0984961T3
(da)
|
1997-04-01 |
2001-09-17 |
Astrazeneca Ab |
Azaindener
|
|
US6245804B1
(en)
|
1997-05-30 |
2001-06-12 |
Schering Aktiengesellschaft |
Nonsteroidal gestagens
|
|
US6307047B1
(en)
|
1997-08-22 |
2001-10-23 |
Abbott Laboratories |
Prostaglandin endoperoxide H synthase biosynthesis inhibitors
|
|
US6348468B1
(en)
|
1997-11-19 |
2002-02-19 |
Kowa Co., Ltd. |
Pyridazine compounds and compositions containing the same
|
|
EP0934933A1
(en)
|
1998-02-06 |
1999-08-11 |
Byk Gulden Lomberg Chemische Fabrik GmbH |
Phthalazinones
|
|
TWI241295B
(en)
|
1998-03-02 |
2005-10-11 |
Kowa Co |
Pyridazine derivative and medicine containing the same as effect component
|
|
AU748816B2
(en)
|
1998-07-16 |
2002-06-13 |
Shionogi & Co., Ltd. |
Pyrimidine derivatives exhibiting antitumor activity
|
|
US6271380B1
(en)
|
1998-12-30 |
2001-08-07 |
Dupont Pharmaceuticals Company |
1H-imidazo[4,5-d]pyridazin-7-ones, 3H-imidazo-[4,5-c]pyridin-4-ones and corresponding thiones as corticotropin releasing factor (CRF) receptor ligands
|
|
CN1297916A
(zh)
|
1999-11-26 |
2001-06-06 |
上海博容基因开发有限公司 |
一种新的多肽——人含溴基结构域的蛋白95和编码这种多肽的多核苷酸
|
|
DE10010423A1
(de)
|
2000-03-03 |
2001-09-06 |
Bayer Ag |
Substituierte 2,5-Dimethyldihydropyridazinone und ihre Verwendung
|
|
CN1315397A
(zh)
|
2000-03-28 |
2001-10-03 |
上海博德基因开发有限公司 |
一种新的多肽——人溴基结构域10和编码这种多肽的多核苷酸
|
|
WO2002001935A1
(en)
|
2000-07-04 |
2002-01-10 |
Robert John Eyre |
Harvesting machine
|
|
US20030114448A1
(en)
|
2001-05-31 |
2003-06-19 |
Millennium Pharmaceuticals, Inc. |
Inhibitors of factor Xa
|
|
JP2003313169A
(ja)
|
2002-04-19 |
2003-11-06 |
Otsuka Chemical Holdings Co Ltd |
4,4−ジフルオロ−3−ブテニル化合物及び農園芸用殺虫・殺ダニ剤
|
|
ES2195785B1
(es)
|
2002-05-16 |
2005-03-16 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de piridazin-3(2h)-ona.
|
|
AU2003249539A1
(en)
|
2002-08-13 |
2004-02-25 |
Warner-Lambert Company Llc |
Cyclic compounds containing zinc binding groups as matrix metalloproteinase inhibitors
|
|
MXPA05001603A
(es)
|
2002-08-13 |
2005-04-25 |
Warner Lambert Co |
Derivados monociclicos como inhibidores de metaloproteinasa de matriz.
|
|
WO2005000818A1
(en)
|
2003-06-27 |
2005-01-06 |
Warner-Lambert Company Llc |
5-substituted-4-`(substituted phenyl)!amino!-2-pyridone deviatives for use as mek inhibitors
|
|
AU2004257025B9
(en)
|
2003-06-27 |
2010-05-27 |
Msd K.K. |
Heteroaryloxy nitrogenous saturated heterocyclic derivative
|
|
WO2005013982A1
(en)
|
2003-08-06 |
2005-02-17 |
Vertex Pharmaceuticals Incorporated |
Aminotriazole compounds useful as inhibitors of protein kinases
|
|
TWI339206B
(en)
*
|
2003-09-04 |
2011-03-21 |
Vertex Pharma |
Compositions useful as inhibitors of protein kinases
|
|
AU2004285449A1
(en)
|
2003-10-20 |
2005-05-12 |
Merck & Co., Inc. |
Hydroxy pyridopyrrolopyrazine dione compounds useful as HIV integrase inhibitors
|
|
US7223733B2
(en)
|
2004-03-31 |
2007-05-29 |
National University Of Singapore |
Modulation of TRIP-Br function and method of treating proliferative disorders
|
|
KR100958829B1
(ko)
*
|
2004-09-03 |
2010-05-25 |
주식회사유한양행 |
피롤로[2,3-c]피리딘 유도체 및 그의 제조방법
|
|
GB0420970D0
(en)
|
2004-09-21 |
2004-10-20 |
Smithkline Beecham Corp |
Novel triazoloquinoline compounds
|
|
WO2006038734A1
(en)
|
2004-10-08 |
2006-04-13 |
Astellas Pharma Inc. |
Pyridazinone derivatives cytokines inhibitors
|
|
US20080090827A1
(en)
|
2004-11-30 |
2008-04-17 |
Artesian Therapeutics, Inc. |
Compounds With Mixed Pde-Inhibitory and Beta-Adrenergic Antagonist or Partial Agonist Activity For Treatment of Heart Failure
|
|
CA2588867A1
(en)
|
2004-12-01 |
2006-06-08 |
Banyu Pharmaceutical Co., Ltd. |
Substituted pyridone derivative
|
|
CA2599925A1
(en)
|
2005-03-14 |
2006-09-21 |
Merck & Co., Inc. |
Cgrp receptor antagonists
|
|
US20060276496A1
(en)
|
2005-03-17 |
2006-12-07 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Anti-Cytokine Heterocyclic Compounds
|
|
WO2006112331A1
(ja)
|
2005-04-13 |
2006-10-26 |
Dainippon Simitomo Pharma Co., Ltd. |
新規縮合ピロール誘導体
|
|
WO2006129623A1
(ja)
|
2005-05-30 |
2006-12-07 |
Mitsubishi Tanabe Pharma Corporation |
チエノトリアゾロジアゼピン化合物及びその医薬としての用途
|
|
WO2007008145A1
(en)
|
2005-07-08 |
2007-01-18 |
Astrazeneca Ab |
Heterocyclic sulfonamide derivatives as inhibitors of factor xa
|
|
WO2007008144A1
(en)
|
2005-07-08 |
2007-01-18 |
Astrazeneca Ab |
Heterocyclic sulfonamide derivatives as inhibitors of factor xa
|
|
CA2627497C
(en)
|
2005-10-28 |
2014-10-14 |
Takeda Pharmaceutical Company Limited |
Heterocyclic amide compound and use thereof
|
|
EP1966141A1
(en)
|
2005-12-14 |
2008-09-10 |
Brystol-Myers Squibb Company |
Six-membered heterocycles useful as serine protease inhibitors
|
|
US20070142414A1
(en)
|
2005-12-16 |
2007-06-21 |
Pharmacia Italia S.P.A. |
N-substituted pyrrolopyridinones active as kinase inhibitors
|
|
HRP20130044T1
(hr)
|
2006-07-25 |
2013-02-28 |
Cephalon, Inc. |
Derivati piridizinona
|
|
WO2008024978A2
(en)
|
2006-08-24 |
2008-02-28 |
Serenex, Inc. |
Tetrahydroindolone and tetrahydroindazolone derivatives
|
|
US7838523B2
(en)
|
2006-09-11 |
2010-11-23 |
Cgi Pharmaceuticals, Inc. |
Certain substituted amides, method of making, and method of use thereof
|
|
KR20090087027A
(ko)
|
2006-11-13 |
2009-08-14 |
일라이 릴리 앤드 캄파니 |
염증 질환 및 암의 치료를 위한 티에노피리미디논
|
|
WO2008133669A2
(en)
|
2006-12-14 |
2008-11-06 |
Gilead Sciences, Inc. |
Viral inhibitors
|
|
JP2008156311A
(ja)
|
2006-12-26 |
2008-07-10 |
Institute Of Physical & Chemical Research |
Brd2ブロモドメイン結合剤
|
|
US20080312307A1
(en)
|
2007-05-25 |
2008-12-18 |
Takeda Pharmaceutical Company Limited |
Mapk/erk kinase inhibitors
|
|
JP5470557B2
(ja)
|
2007-07-26 |
2014-04-16 |
ヴァイティー ファーマシューティカルズ,インコーポレイテッド |
11β−ヒドロキシステロイドデヒドロゲナーゼ1型の阻害剤の合成
|
|
CL2008002793A1
(es)
|
2007-09-20 |
2009-09-04 |
Cgi Pharmaceuticals Inc |
Compuestos derivados de amidas sustituidas, inhibidores de la actividad de btk; composicion farmaceutica que los comprende; utiles en el tratamiento del cancer, trastornos oseos, enfermedades autoinmunes, entre otras
|
|
CN101835755B
(zh)
|
2007-10-23 |
2013-12-11 |
霍夫曼-拉罗奇有限公司 |
激酶抑制剂
|
|
WO2009054790A1
(en)
|
2007-10-26 |
2009-04-30 |
Astrazeneca Ab |
Amide linked heteroaromatic derivatives as modulators of mglur5
|
|
WO2009086303A2
(en)
|
2007-12-21 |
2009-07-09 |
University Of Rochester |
Method for altering the lifespan of eukaryotic organisms
|
|
KR101600634B1
(ko)
|
2007-12-28 |
2016-03-07 |
미쓰비시 타나베 파마 코퍼레이션 |
항암제
|
|
US20100137320A1
(en)
|
2008-02-29 |
2010-06-03 |
Schering Corporation |
Gamma secretase modulators
|
|
RU2531272C2
(ru)
|
2008-05-01 |
2014-10-20 |
Вайтаи Фармасьютиклз, Инк. |
Циклические ингибиторы 11бета-гидроксистероид-дегидрогеназы 1
|
|
EP2291370B1
(en)
|
2008-05-01 |
2013-11-27 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
US8242111B2
(en)
|
2008-05-01 |
2012-08-14 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
|
|
WO2009142732A2
(en)
|
2008-05-20 |
2009-11-26 |
Cephalon, Inc. |
Substituted pyridazinone derivatives as histamine-3 (h3) receptor ligands
|
|
NZ590495A
(en)
|
2008-07-25 |
2012-10-26 |
Vitae Pharmaceuticals Inc |
Dihydropyridin-phenyl-3-oxazinan-2-ones as inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
AU2009282480B2
(en)
|
2008-08-11 |
2015-05-07 |
Children's Medical Center Corporation |
Halofuginone analogs for inhibition of tRNA synthetases and uses thereof
|
|
SI2358686T1
(sl)
|
2008-11-20 |
2013-05-31 |
Merck Sharp & Dohme Corp. |
Aril metil benzokuinazolinon M1 receptor pozitivnih alosteričnih modulatorjev
|
|
EP2196465A1
(en)
|
2008-12-15 |
2010-06-16 |
Almirall, S.A. |
(3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors
|
|
GEP20156309B
(en)
|
2009-04-30 |
2015-07-10 |
Vitae Pharmaceuticals Inc |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
EP3050885B1
(en)
|
2009-11-05 |
2017-10-18 |
GlaxoSmithKline LLC |
Benzodiazepine bromodomain inhibitor
|
|
GB0919432D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Use
|
|
AU2010314395B2
(en)
|
2009-11-05 |
2015-04-09 |
Glaxosmithkline Llc |
Benzodiazepine bromodomain inhibitor
|
|
GB0919426D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB0919434D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB0919423D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
WO2011054851A1
(en)
|
2009-11-05 |
2011-05-12 |
Glaxosmithkline Llc |
Novel process
|
|
US20130061612A1
(en)
|
2009-11-11 |
2013-03-14 |
E.I. Du Pont De Nemours And Company |
Refrigerant storage in secondary loop refrigeration systems
|
|
KR20130069640A
(ko)
|
2010-04-23 |
2013-06-26 |
키네타, 인크. |
항-바이러스 화합물
|
|
PL2902030T3
(pl)
|
2010-05-14 |
2017-07-31 |
Dana-Farber Cancer Institute, Inc. |
Związki tienotriazolodiazepinowe do leczenia nowotworu
|
|
JP5844358B2
(ja)
|
2010-06-22 |
2016-01-13 |
グラクソスミスクライン エルエルシー |
ベンゾトリアゾロジアゼピン化合物を含むブロモドメイン阻害剤
|
|
WO2012075456A1
(en)
|
2010-12-02 |
2012-06-07 |
Constellation Pharmaceuticals |
Bromodomain inhibitors and uses thereof
|
|
KR20140102276A
(ko)
|
2011-12-07 |
2014-08-21 |
어펙티바,아이엔씨. |
광고 효과의 감정 기반 평가
|
|
WO2013097052A1
(en)
*
|
2011-12-30 |
2013-07-04 |
Abbott Laboratories |
Bromodomain inhibitors
|
|
US20130188311A1
(en)
|
2012-01-23 |
2013-07-25 |
International Business Machines Corporation |
Cooling and noise-reduction apparatus
|
|
CA2870931A1
(en)
|
2012-04-20 |
2013-10-24 |
Abbvie Inc. |
Isoindolone derivatives
|
|
AU2012382373A1
(en)
|
2012-06-12 |
2014-12-11 |
Abbvie Inc. |
Pyridinone and pyridazinone derivatives
|
|
EP2862072B1
(en)
|
2012-06-15 |
2022-09-07 |
Intel Corporation |
A load store buffer agnostic to threads implementing forwarding from different threads based on store seniority
|
|
US20140094456A1
(en)
|
2012-10-02 |
2014-04-03 |
Intermune, Inc. |
Anti-fibrotic pyridinones
|
|
AR092742A1
(es)
|
2012-10-02 |
2015-04-29 |
Intermune Inc |
Piridinonas antifibroticas
|
|
WO2014125408A2
(en)
*
|
2013-02-12 |
2014-08-21 |
Aurigene Discovery Technologies Limited |
Substituted 1h-pyrrolopyridinone derivatives as kinase inhibitors
|
|
MX2015012158A
(es)
|
2013-03-11 |
2015-12-01 |
Abbvie Inc |
Inhibidores de bomodominio tetraciclicos fusionados.
|
|
US9050346B2
(en)
|
2013-03-11 |
2015-06-09 |
Abbvie Inc. |
Bromodomain inhibitors
|
|
BR112015022643A2
(pt)
*
|
2013-03-12 |
2017-07-18 |
Abbvie Inc |
inibidores diidro-pirrolpiridinona
|
|
BR112015022551A2
(pt)
|
2013-03-12 |
2017-07-18 |
Abbvie Inc |
inibidores de amido pirrol
|
|
UY35395A
(es)
|
2013-03-12 |
2014-10-31 |
Abbvie Inc |
Inhibidores de bromodominios tetracíclicos
|
|
WO2014206150A1
(en)
|
2013-06-28 |
2014-12-31 |
Abbvie Inc. |
Bromodomain inhibitors
|
|
AR096758A1
(es)
|
2013-06-28 |
2016-02-03 |
Abbvie Inc |
Inhibidores cristalinos de bromodominios
|
|
CN103387576A
(zh)
*
|
2013-08-09 |
2013-11-13 |
中国药科大学 |
基于嘌呤结构的芳酰胺类Raf激酶抑制剂及其制备方法和用途
|
|
SG10201804471PA
(en)
*
|
2013-10-18 |
2018-07-30 |
Celgene Quanticel Research Inc |
Bromodomain inhibitors
|
|
WO2015081246A1
(en)
|
2013-11-26 |
2015-06-04 |
Incyte Corporation |
Bicyclic heterocycles as bet protein inhibitors
|
|
US9399640B2
(en)
|
2013-11-26 |
2016-07-26 |
Incyte Corporation |
Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors
|
|
WO2015081189A1
(en)
|
2013-11-26 |
2015-06-04 |
Incyte Corporation |
Bicyclic heterocycles as bet protein inhibitors
|
|
WO2015081280A1
(en)
|
2013-11-26 |
2015-06-04 |
Coferon, Inc. |
Bromodomain ligands capable of dimerizing in an aqueous solution
|
|
EP3089970B1
(en)
|
2013-12-09 |
2018-10-17 |
AbbVie Inc. |
Dihydropyridinone and dihydropyridazinone derivatives useful as bromodomain inhibitors
|
|
CN105980392A
(zh)
|
2013-12-10 |
2016-09-28 |
艾伯维公司 |
溴区结构域抑制剂
|
|
PL3134403T3
(pl)
|
2014-04-23 |
2020-07-13 |
Incyte Corporation |
1H-pirolo[2,3-c]pirydyn-7(6H)-ony i pirazolo[3,4-c]pirydyn-7(6H)-ony jako inhibitory białek BET
|
|
MA40940A
(fr)
|
2014-11-10 |
2017-09-19 |
Constellation Pharmaceuticals Inc |
Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines
|
|
US10683290B2
(en)
|
2015-05-11 |
2020-06-16 |
Bristol-Myers Squibb Company |
Tricyclic compounds as anticancer agents
|
|
ES2770349T3
(es)
|
2015-05-12 |
2020-07-01 |
Bristol Myers Squibb Co |
Compuestos de 5H-pirido[3,2-b]indol como agentes antineoplásicos
|
|
JP6606444B2
(ja)
|
2016-03-10 |
2019-11-13 |
株式会社Subaru |
車両用制御装置
|
|
PL3442947T3
(pl)
|
2016-04-15 |
2023-10-02 |
Epizyme, Inc. |
Związki arylowe lub heteroarylowe podstawione aminą jako inhibitory ehmt1 i ehmt2
|
|
PT3442972T
(pt)
*
|
2016-04-15 |
2020-05-29 |
Abbvie Inc |
Inibidores de bromodomínio
|
|
CN109311889B
(zh)
|
2016-04-15 |
2021-11-16 |
缆图药品公司 |
激活素受体样激酶抑制剂
|
|
CN108884074B
(zh)
|
2016-04-15 |
2021-07-02 |
先正达参股股份有限公司 |
除草哒嗪酮化合物
|
|
AU2017251155B2
(en)
|
2016-04-15 |
2021-08-05 |
Elanco Animal Health Gmbh |
Pyrazolopyrimidine derivatives
|
|
US11298354B2
(en)
|
2016-06-09 |
2022-04-12 |
Dana-Farber Cancer Institute, Inc. |
Methods of use and pharmaceutical combinations of HDAC inhibitors with BET inhibitors
|
|
WO2017216772A2
(en)
|
2016-06-16 |
2017-12-21 |
The University Of Chicago |
Methods and compositions for treating breast and prostate cancer
|
|
WO2017223268A1
(en)
|
2016-06-22 |
2017-12-28 |
Yale University |
COMPOSITIONS AND METHODS OF RESENSITIZING CELLS TO BROMODOMAIN AND EXTRATERMINAL DOMAIN PROTEIN INHIBITORS (BETi)
|
|
EP3526197A4
(en)
|
2016-10-14 |
2020-03-18 |
AbbVie Inc. |
BROMDOMAIN INHIBITORS
|
|
AU2016426480A1
(en)
|
2016-10-14 |
2019-04-18 |
Abbvie Inc. |
Bromodomain inhibitors
|
|
WO2018095933A1
(en)
|
2016-11-22 |
2018-05-31 |
Université D'aix-Marseille (Amu) |
Method of prognosticating, or for determining the efficiency of a compound for treating cancer
|
|
CN110167939B
(zh)
|
2017-01-11 |
2021-12-31 |
江苏豪森药业集团有限公司 |
吡咯并[2,3-c]吡啶类衍生物、其制备方法及其在医药上的应用
|
|
WO2018188047A1
(en)
|
2017-04-14 |
2018-10-18 |
Abbvie Inc. |
Bromodomain inhibitors
|
|
CN108976278B
(zh)
|
2017-06-05 |
2021-04-06 |
海创药业股份有限公司 |
一种嵌合分子及其制备和应用
|
|
CN108690020A
(zh)
|
2018-07-04 |
2018-10-23 |
清华大学 |
一种靶向降解bet蛋白的化合物及其应用
|