|
NO760996L
(OSRAM)
|
1975-03-25 |
1976-09-28 |
Byk Gulden Lomberg Chem Fab |
|
|
US4072746A
(en)
|
1975-10-14 |
1978-02-07 |
Sterling Drug Inc. |
3-Amino-5-(pyridinyl)-2(1H)-pyridinones
|
|
US4004012A
(en)
|
1975-10-14 |
1977-01-18 |
Sterling Drug Inc. |
3-Cyano-5-(pyridinyl)-2(1H)-pyridinones
|
|
DE2845456A1
(de)
|
1978-10-19 |
1980-08-14 |
Merck Patent Gmbh |
6-arylpyridazin-3-one und verfahren zu ihrer herstellung
|
|
US4298609A
(en)
|
1979-08-30 |
1981-11-03 |
Sterling Drug Inc. |
4,5-Dihydro-6-(4-pyridinyl)-3-pyridazinol and salts, their preparation and use as blood pressure lowering agents
|
|
FR2478640A1
(fr)
|
1980-03-24 |
1981-09-25 |
Sanofi Sa |
Nouvelles thieno (2,3-d) pyridazinones-4 et thieno (2,3-d) pyridazinones-7, leur procede de preparation et leur therapeutique
|
|
US4486431A
(en)
|
1981-01-14 |
1984-12-04 |
Sterling Drug Inc. |
Cardiotonic use of 4,5-dihydro-6-(4-pyridinyl)-3(2H)-pyridazinones
|
|
US4338446A
(en)
|
1980-04-28 |
1982-07-06 |
Sterling Drug Inc. |
Di-(lower-alkyl)hydroxy-[2-oxo-2-(pyridinyl)ethyl]-propanedioates
|
|
US4304776A
(en)
|
1980-04-28 |
1981-12-08 |
Sterling Drug Inc. |
4-Substituted-6-(pyridinyl)-3(2h)-pyridazinones and their use as intermediates and cardiotonics
|
|
US4346221A
(en)
|
1980-04-28 |
1982-08-24 |
Sterling Drug Inc. |
Preparation of 4-amino-6-(pyridinyl)-3(2H)-pyridazinones from 6-(pyridinyl)-3(2H)-pyridazinones
|
|
US4305943A
(en)
|
1980-04-28 |
1981-12-15 |
Sterling Drug Inc. |
4-Amino-6-(pyridinyl)-3(2H)-pyridazinones and their use as cardiotonics
|
|
US4337253A
(en)
|
1980-04-28 |
1982-06-29 |
Sterling Drug Inc. |
4,5-Dihydro-2-methyl-6-(4-pyridinyl)-3(2H)-pyridazinone and its use as a cardiotonic
|
|
US4559352A
(en)
|
1981-03-30 |
1985-12-17 |
Sterling Drug Inc. |
1,2-Dihydro-2-oxo-5-(hydroxy-and/or amino-phenyl)-nicotinonitriles and cardiotonic use thereof
|
|
US4404203A
(en)
|
1981-05-14 |
1983-09-13 |
Warner-Lambert Company |
Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
|
|
US4397854A
(en)
|
1981-05-14 |
1983-08-09 |
Warner-Lambert Company |
Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
|
|
US4515797A
(en)
|
1981-09-08 |
1985-05-07 |
Sterling Drug Inc. |
3-Amino-5-(hydroxy- and/or aminophenyl)-6-(lower-alkyl)-2(1H)-pyridinones and cardiotonic use thereof
|
|
US4465686A
(en)
|
1981-09-08 |
1984-08-14 |
Sterling Drug Inc. |
5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation
|
|
US4353905A
(en)
|
1981-09-17 |
1982-10-12 |
Warner-Lambert Company |
Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones
|
|
US4599423A
(en)
|
1982-04-26 |
1986-07-08 |
Sterling Drug Inc. |
Preparation of 5-(hydroxy- and/or aminophenyl-6-lower-alkyl)-2(1H)-pyridinones
|
|
US4734415A
(en)
|
1982-08-13 |
1988-03-29 |
Warner-Lambert Company |
Substituted 4,5-dihydro-6-(substituted)-phenyl-3(2H)-pyridazinones and 6-(substituted) phenyl-3(2H)-pyridazinones
|
|
DE3241102A1
(de)
|
1982-11-06 |
1984-05-10 |
A. Nattermann & Cie GmbH, 5000 Köln |
Imidazolylalkylthienyl-tetrahydropyridazine und verfahren zu ihrer herstellung
|
|
DE3321012A1
(de)
|
1983-06-10 |
1984-12-13 |
A. Nattermann & Cie GmbH, 5000 Köln |
Substituierte 4,5-dihydro-6-(thien-2-yl)-3(2h)-pyridazinone und 6-(thien-2-yl)-3(2h)-pyridazinone sowie verfahren zu ihrer herstellung
|
|
US4666902A
(en)
|
1983-06-20 |
1987-05-19 |
Cassella Aktiengesellschaft |
Tetrahydropyridazinone derivatives, processes for their preparation and their use
|
|
GB8323553D0
(en)
|
1983-09-02 |
1983-10-05 |
Smith Kline French Lab |
Pharmaceutical compositions
|
|
US4816454A
(en)
|
1984-09-21 |
1989-03-28 |
Cassella Aktiengesellschaft |
4,5-dihydro-3(2H)-pyridazinones and their pharmacological use
|
|
US5221543A
(en)
|
1986-10-22 |
1993-06-22 |
Firma Wilhelm Fette Gmbh |
Method of making a fast release stabilized aspartame ingredient for chewing gum
|
|
US4863745A
(en)
|
1986-10-22 |
1989-09-05 |
Wm. Wrigley Jr. Company |
Chewing gum containing zein coated high-potency sweetener and method
|
|
US5217735A
(en)
|
1986-10-22 |
1993-06-08 |
Wm. Wrigley Jr. Company |
Method of making chewing gum with delayed release ingredients
|
|
US5192563A
(en)
|
1986-10-22 |
1993-03-09 |
Wm. Wrigley, Jr. Company |
Strongly mint-flavored chewing gums with reduced bitterness and harshness
|
|
US5112625A
(en)
|
1989-02-15 |
1992-05-12 |
Wm. Wrigley Jr. Company |
Aqueous zein coated sweeteners and other ingredients for chewing gum
|
|
US4908371A
(en)
|
1987-11-10 |
1990-03-13 |
Ciba-Geigy Corporation |
Esterified hydroxy dihydropyridinones for treating diseases associated with trivalent metal ion overload
|
|
US4919941A
(en)
|
1987-12-18 |
1990-04-24 |
Wm. Wrigley Jr. Company |
Chewing gum containing delayed release protein sweetener and method
|
|
DE4134467A1
(de)
|
1991-10-18 |
1993-04-22 |
Thomae Gmbh Dr K |
Heterobiarylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
|
JP3120857B2
(ja)
|
1990-02-19 |
2000-12-25 |
中外製薬株式会社 |
新規な縮合複素環化合物とこれを用いた抗喘息剤
|
|
DE4023369A1
(de)
|
1990-07-23 |
1992-01-30 |
Thomae Gmbh Dr K |
Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
|
ATE180475T1
(de)
|
1990-09-21 |
1999-06-15 |
Rohm & Haas |
Dihydropyridazinone und pyridazinone als fungizide
|
|
CA2069877A1
(en)
|
1990-10-02 |
1992-04-03 |
Michio Nakanishi |
Ethynylphenyl derivative substituted by pyridazinone and medicament for circulatory disease containing the same as an effective ingredient
|
|
DE4127404A1
(de)
|
1991-08-19 |
1993-02-25 |
Thomae Gmbh Dr K |
Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
|
CN1038249C
(zh)
|
1991-08-28 |
1998-05-06 |
罗姆和哈斯公司 |
含有二氢哒嗪酮及其相关化合物的杀菌组合物
|
|
EP0612321B1
(en)
|
1991-10-09 |
1999-08-25 |
Syntex (U.S.A.) Inc. |
Pyrido pyridazinone and pyridazinthione compounds with pde iv inhibiting activity
|
|
US5716954A
(en)
|
1991-10-09 |
1998-02-10 |
Syntex U.S.A. Inc. |
Benzopyridazinone and pyridopyridazinone compounds
|
|
DE4237656A1
(de)
|
1992-06-13 |
1993-12-16 |
Merck Patent Gmbh |
Benzimidazolderivate
|
|
CA2147504A1
(en)
|
1992-11-02 |
1994-05-11 |
Prasun K. Chakravarty |
Substituted phthalazinones as neurotensin antagonists
|
|
US5814651A
(en)
|
1992-12-02 |
1998-09-29 |
Pfizer Inc. |
Catechol diethers as selective PDEIV inhibitors
|
|
EP0634404A1
(en)
|
1993-07-13 |
1995-01-18 |
Rhone Poulenc Agriculture Ltd. |
Phtalazin derivatives and their use as pesticides
|
|
GB9314412D0
(en)
|
1993-07-13 |
1993-08-25 |
Rhone Poulenc Agriculture |
New compositions of matter
|
|
TW263498B
(OSRAM)
|
1993-11-10 |
1995-11-21 |
Takeda Pharm Industry Co Ltd |
|
|
JP3247540B2
(ja)
|
1994-05-12 |
2002-01-15 |
株式会社日立製作所 |
パケット化通信装置および切替え装置
|
|
US5466697A
(en)
|
1994-07-13 |
1995-11-14 |
Syntex (U.S.A.) Inc. |
8-phenyl-1,6-naphthyridin-5-ones
|
|
AU691673B2
(en)
|
1994-11-14 |
1998-05-21 |
Dow Agrosciences Llc |
Pyridazinones and their use as fungicides
|
|
JPH08337583A
(ja)
|
1995-04-13 |
1996-12-24 |
Takeda Chem Ind Ltd |
複素環化合物およびその製造法
|
|
US5635494A
(en)
|
1995-04-21 |
1997-06-03 |
Rohm And Haas Company |
Dihydropyridazinones and pyridazinones and their use as fungicides and insecticides
|
|
JPH11508267A
(ja)
|
1995-06-26 |
1999-07-21 |
藤沢薬品工業株式会社 |
ピラゾール化合物および医薬組成物
|
|
IL118631A
(en)
|
1995-06-27 |
2002-05-23 |
Tanabe Seiyaku Co |
History of pyridazinone and processes for their preparation
|
|
AR003978A1
(es)
|
1995-08-25 |
1998-09-30 |
Rohm & Haas |
Composiciones de acidos grasos y piridazinonas que tienen efectos fungitoxicos sinergicos y metodos para controlar hongos.
|
|
DE69717160T2
(de)
|
1996-09-13 |
2003-05-08 |
Mitsubishi Pharma Corp., Osaka |
Thienotriazolodiazepinverbindungen und ihre medizinischen anwendungen
|
|
US5855654A
(en)
|
1997-01-30 |
1999-01-05 |
Rohm And Haas Company |
Pyridazinones as marine antifouling agents
|
|
WO1998043971A1
(en)
|
1997-04-01 |
1998-10-08 |
Astra Pharmaceuticals Ltd. |
Novel pyridine derivatives and pharmaceutical compositions containing them
|
|
US6245804B1
(en)
|
1997-05-30 |
2001-06-12 |
Schering Aktiengesellschaft |
Nonsteroidal gestagens
|
|
US6307047B1
(en)
|
1997-08-22 |
2001-10-23 |
Abbott Laboratories |
Prostaglandin endoperoxide H synthase biosynthesis inhibitors
|
|
NZ504045A
(en)
|
1997-11-19 |
2001-06-29 |
Kowa Co |
Pyridazine derivatives with inhibitory action against interleukin-1-beta production
|
|
IL136499A0
(en)
|
1997-12-05 |
2001-06-14 |
Astrazeneca Uk Ltd Astrazeneca |
Pyrrolo-, thieno-, furano- and pyrazolo-[3,4,d] pypyrrolo-, thieno-, furano- and pyrazolo-[3,4,d] pyridazinone compounds, process for their preparatioridaziones compounds, process for their preparation, pharmaceutical compositions containing them, a n, pharmaceutical compositions containing them, a process for prepating the pharmaceutical compositiprocess for preparing the pharmaceutical compositions, and use thereof ons, and use thereof
|
|
EP0934933A1
(en)
|
1998-02-06 |
1999-08-11 |
Byk Gulden Lomberg Chemische Fabrik GmbH |
Phthalazinones
|
|
TWI241295B
(en)
|
1998-03-02 |
2005-10-11 |
Kowa Co |
Pyridazine derivative and medicine containing the same as effect component
|
|
JP3910365B2
(ja)
|
1998-07-16 |
2007-04-25 |
塩野義製薬株式会社 |
抗腫瘍活性を有するピリミジン誘導体
|
|
US6271380B1
(en)
|
1998-12-30 |
2001-08-07 |
Dupont Pharmaceuticals Company |
1H-imidazo[4,5-d]pyridazin-7-ones, 3H-imidazo-[4,5-c]pyridin-4-ones and corresponding thiones as corticotropin releasing factor (CRF) receptor ligands
|
|
CN1297916A
(zh)
|
1999-11-26 |
2001-06-06 |
上海博容基因开发有限公司 |
一种新的多肽——人含溴基结构域的蛋白95和编码这种多肽的多核苷酸
|
|
DE10010423A1
(de)
|
2000-03-03 |
2001-09-06 |
Bayer Ag |
Substituierte 2,5-Dimethyldihydropyridazinone und ihre Verwendung
|
|
CN1315397A
(zh)
|
2000-03-28 |
2001-10-03 |
上海博德基因开发有限公司 |
一种新的多肽——人溴基结构域10和编码这种多肽的多核苷酸
|
|
DE60038318D1
(de)
|
2000-07-04 |
2008-04-24 |
Robert John Eyre |
Erntemaschine
|
|
US20030114448A1
(en)
|
2001-05-31 |
2003-06-19 |
Millennium Pharmaceuticals, Inc. |
Inhibitors of factor Xa
|
|
JP2003313169A
(ja)
|
2002-04-19 |
2003-11-06 |
Otsuka Chemical Holdings Co Ltd |
４，４−ジフルオロ−３−ブテニル化合物及び農園芸用殺虫・殺ダニ剤
|
|
ES2195785B1
(es)
|
2002-05-16 |
2005-03-16 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de piridazin-3(2h)-ona.
|
|
JP2006501215A
(ja)
|
2002-08-13 |
2006-01-12 |
ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー |
マトリックスメタロプロテイナーゼ阻害剤としての単環式誘導体
|
|
AU2003249539A1
(en)
|
2002-08-13 |
2004-02-25 |
Warner-Lambert Company Llc |
Cyclic compounds containing zinc binding groups as matrix metalloproteinase inhibitors
|
|
JP4735261B2
(ja)
|
2003-06-27 |
2011-07-27 |
Ｍｓｄ株式会社 |
ヘテロアリールオキシ含窒素飽和ヘテロ環誘導体
|
|
WO2005000818A1
(en)
|
2003-06-27 |
2005-01-06 |
Warner-Lambert Company Llc |
5-substituted-4-`(substituted phenyl)!amino!-2-pyridone deviatives for use as mek inhibitors
|
|
AR045731A1
(es)
|
2003-08-06 |
2005-11-09 |
Vertex Pharma |
Compuestos de aminotriazol utiles como inhibidores de quinasas de proteinas
|
|
TWI339206B
(en)
*
|
2003-09-04 |
2011-03-21 |
Vertex Pharma |
Compositions useful as inhibitors of protein kinases
|
|
WO2005041664A1
(en)
|
2003-10-20 |
2005-05-12 |
Merck & Co., Inc. |
Hydroxy pyridopyrrolopyrazine dione compounds useful as hiv integrase inhibitors
|
|
US7223733B2
(en)
|
2004-03-31 |
2007-05-29 |
National University Of Singapore |
Modulation of TRIP-Br function and method of treating proliferative disorders
|
|
KR100958829B1
(ko)
*
|
2004-09-03 |
2010-05-25 |
주식회사유한양행 |
피롤로[2,3-ｃ]피리딘 유도체 및 그의 제조방법
|
|
GB0420970D0
(en)
|
2004-09-21 |
2004-10-20 |
Smithkline Beecham Corp |
Novel triazoloquinoline compounds
|
|
WO2006038734A1
(en)
|
2004-10-08 |
2006-04-13 |
Astellas Pharma Inc. |
Pyridazinone derivatives cytokines inhibitors
|
|
US20080090827A1
(en)
|
2004-11-30 |
2008-04-17 |
Artesian Therapeutics, Inc. |
Compounds With Mixed Pde-Inhibitory and Beta-Adrenergic Antagonist or Partial Agonist Activity For Treatment of Heart Failure
|
|
EP1820797A4
(en)
|
2004-12-01 |
2009-10-28 |
Banyu Pharma Co Ltd |
SUBSTITUTED PYRIDONE DERIVATIVE
|
|
CA2599925A1
(en)
|
2005-03-14 |
2006-09-21 |
Merck & Co., Inc. |
Cgrp receptor antagonists
|
|
US20060276496A1
(en)
|
2005-03-17 |
2006-12-07 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Anti-Cytokine Heterocyclic Compounds
|
|
JPWO2006112331A1
(ja)
|
2005-04-13 |
2008-12-11 |
大日本住友製薬株式会社 |
新規縮合ピロール誘導体
|
|
WO2006129623A1
(ja)
|
2005-05-30 |
2006-12-07 |
Mitsubishi Tanabe Pharma Corporation |
チエノトリアゾロジアゼピン化合物及びその医薬としての用途
|
|
WO2007008145A1
(en)
|
2005-07-08 |
2007-01-18 |
Astrazeneca Ab |
Heterocyclic sulfonamide derivatives as inhibitors of factor xa
|
|
WO2007008144A1
(en)
|
2005-07-08 |
2007-01-18 |
Astrazeneca Ab |
Heterocyclic sulfonamide derivatives as inhibitors of factor xa
|
|
US7915267B2
(en)
|
2005-10-28 |
2011-03-29 |
Takeda Pharmaceutical Company Limited |
Heterocyclic amide compound and use thereof
|
|
WO2007070818A1
(en)
|
2005-12-14 |
2007-06-21 |
Bristol-Myers Squibb Company |
Six-membered heterocycles useful as serine protease inhibitors
|
|
US20070142414A1
(en)
|
2005-12-16 |
2007-06-21 |
Pharmacia Italia S.P.A. |
N-substituted pyrrolopyridinones active as kinase inhibitors
|
|
JP5335675B2
(ja)
|
2006-07-25 |
2013-11-06 |
セファロン、インク． |
ピリジジノン誘導体
|
|
WO2008024978A2
(en)
|
2006-08-24 |
2008-02-28 |
Serenex, Inc. |
Tetrahydroindolone and tetrahydroindazolone derivatives
|
|
US7838523B2
(en)
|
2006-09-11 |
2010-11-23 |
Cgi Pharmaceuticals, Inc. |
Certain substituted amides, method of making, and method of use thereof
|
|
CN101605797A
(zh)
|
2006-11-13 |
2009-12-16 |
伊莱利利公司 |
治疗炎症疾病和癌症的噻吩并嘧啶酮
|
|
WO2008133669A2
(en)
|
2006-12-14 |
2008-11-06 |
Gilead Sciences, Inc. |
Viral inhibitors
|
|
JP2008156311A
(ja)
|
2006-12-26 |
2008-07-10 |
Institute Of Physical & Chemical Research |
Ｂｒｄ２ブロモドメイン結合剤
|
|
WO2008148034A1
(en)
|
2007-05-25 |
2008-12-04 |
Takeda Pharmaceutical Company Limited |
Mapk/erk kinase inhibitors
|
|
ATE554078T1
(de)
|
2007-07-26 |
2012-05-15 |
Vitae Pharmaceuticals Inc |
Synthese von 11-beta-hydroxysteroid-dehydrogenase-1-hemmern
|
|
CL2008002793A1
(es)
|
2007-09-20 |
2009-09-04 |
Cgi Pharmaceuticals Inc |
Compuestos derivados de amidas sustituidas, inhibidores de la actividad de btk; composicion farmaceutica que los comprende; utiles en el tratamiento del cancer, trastornos oseos, enfermedades autoinmunes, entre otras
|
|
CA2701275C
(en)
|
2007-10-23 |
2016-06-21 |
F. Hoffmann-La Roche Ag |
Kinase inhibitors
|
|
WO2009054790A1
(en)
|
2007-10-26 |
2009-04-30 |
Astrazeneca Ab |
Amide linked heteroaromatic derivatives as modulators of mglur5
|
|
CA2709784A1
(en)
|
2007-12-21 |
2009-07-09 |
University Of Rochester |
Method for altering the lifespan of eukaryotic organisms
|
|
CN101910182B
(zh)
|
2007-12-28 |
2013-07-17 |
田边三菱制药株式会社 |
抗癌剂
|
|
US20100137320A1
(en)
|
2008-02-29 |
2010-06-03 |
Schering Corporation |
Gamma secretase modulators
|
|
WO2009134387A1
(en)
|
2008-05-01 |
2009-11-05 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
JP5451752B2
(ja)
|
2008-05-01 |
2014-03-26 |
ヴァイティー ファーマシューティカルズ，インコーポレイテッド |
１１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
|
|
NZ588954A
(en)
|
2008-05-01 |
2012-08-31 |
Vitae Pharmaceuticals Inc |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
EP2328586A2
(en)
|
2008-05-20 |
2011-06-08 |
Cephalon, Inc. |
Substituted pyridazinone derivatives as histamine-3 (h3) receptor ligands
|
|
PL2324018T3
(pl)
|
2008-07-25 |
2014-02-28 |
Boehringer Ingelheim Int |
Cykliczne inhibitory dehydrogenazy 11 beta-hydroksysteroidowej typu 1
|
|
WO2010019210A2
(en)
|
2008-08-11 |
2010-02-18 |
President And Fellows Of Harvard College |
Halofuginone analogs for inhibition of trna synthetases and uses thereof
|
|
CN102292323B
(zh)
|
2008-11-20 |
2014-12-24 |
默沙东公司 |
芳基甲基苯并喹唑啉酮 m1受体正向变构调节剂
|
|
EP2196465A1
(en)
|
2008-12-15 |
2010-06-16 |
Almirall, S.A. |
(3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors
|
|
KR20120061771A
(ko)
|
2009-04-30 |
2012-06-13 |
비타이 파마슈티컬즈, 인코포레이티드 |
11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
|
|
GB0919432D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Use
|
|
ES2652304T3
(es)
|
2009-11-05 |
2018-02-01 |
Glaxosmithkline Llc |
Compuesto de benzodiacepina novedoso
|
|
GB0919426D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
WO2011054851A1
(en)
|
2009-11-05 |
2011-05-12 |
Glaxosmithkline Llc |
Novel process
|
|
GB0919423D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
EP3050885B1
(en)
|
2009-11-05 |
2017-10-18 |
GlaxoSmithKline LLC |
Benzodiazepine bromodomain inhibitor
|
|
GB0919434D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
WO2011060067A2
(en)
|
2009-11-11 |
2011-05-19 |
E. I. Du Pont De Nemours And Company |
Refrigerant storage in secondary loop refrigeration systems
|
|
WO2011133722A2
(en)
|
2010-04-23 |
2011-10-27 |
Kineta, Inc. |
Anti-viral compounds
|
|
HUE031073T2
(en)
|
2010-05-14 |
2017-06-28 |
Dana Farber Cancer Inst Inc |
Thieno triazolo-diazepine compounds for the treatment of neoplasia
|
|
WO2011161031A1
(en)
|
2010-06-22 |
2011-12-29 |
Glaxosmithkline Llc |
Benzotriazolodiazepine compounds inhibitors of bromodomains
|
|
WO2012075456A1
(en)
|
2010-12-02 |
2012-06-07 |
Constellation Pharmaceuticals |
Bromodomain inhibitors and uses thereof
|
|
KR20140102276A
(ko)
|
2011-12-07 |
2014-08-21 |
어펙티바,아이엔씨. |
광고 효과의 감정 기반 평가
|
|
WO2013097052A1
(en)
|
2011-12-30 |
2013-07-04 |
Abbott Laboratories |
Bromodomain inhibitors
|
|
US20130188311A1
(en)
|
2012-01-23 |
2013-07-25 |
International Business Machines Corporation |
Cooling and noise-reduction apparatus
|
|
HK1206744A1
(en)
|
2012-04-20 |
2016-01-15 |
Abbvie Inc. |
Isoindolone derivatives
|
|
MX2014015156A
(es)
|
2012-06-12 |
2015-08-06 |
Abbvie Inc |
Derivados de piridinona y piridazinona.
|
|
KR101702788B1
(ko)
|
2012-06-15 |
2017-02-03 |
소프트 머신즈, 인크. |
스토어 상위 서열에 기초하여 상이한 스레드들로부터의 포워딩을 구현하는 스레드에 무관한 로드 스토어 버퍼
|
|
AR092742A1
(es)
|
2012-10-02 |
2015-04-29 |
Intermune Inc |
Piridinonas antifibroticas
|
|
US20140094456A1
(en)
|
2012-10-02 |
2014-04-03 |
Intermune, Inc. |
Anti-fibrotic pyridinones
|
|
WO2014125408A2
(en)
*
|
2013-02-12 |
2014-08-21 |
Aurigene Discovery Technologies Limited |
Substituted 1h-pyrrolopyridinone derivatives as kinase inhibitors
|
|
BR112015022674A2
(pt)
|
2013-03-11 |
2017-07-18 |
Abbvie Inc |
inibidores de bromodomínio
|
|
CA2904048A1
(en)
*
|
2013-03-11 |
2014-10-09 |
Abbvie Inc. |
Bromodomain inhibitors
|
|
US9493411B2
(en)
|
2013-03-12 |
2016-11-15 |
Abbvie Inc. |
Pyrrole-3-carboxamide bromodomain inhibitors
|
|
JP6419735B2
(ja)
|
2013-03-12 |
2018-11-07 |
アッヴィ・インコーポレイテッド |
四環系ブロモドメイン阻害剤
|
|
KR20150126696A
(ko)
|
2013-03-12 |
2015-11-12 |
애브비 인코포레이티드 |
디하이드로-피롤로피리디논 브로모도메인 억제제
|
|
AR096758A1
(es)
|
2013-06-28 |
2016-02-03 |
Abbvie Inc |
Inhibidores cristalinos de bromodominios
|
|
SG11201510678TA
(en)
*
|
2013-06-28 |
2016-01-28 |
Abbvie Inc |
Bromodomain inhibitors
|
|
CN103387576A
(zh)
*
|
2013-08-09 |
2013-11-13 |
中国药科大学 |
基于嘌呤结构的芳酰胺类Raf激酶抑制剂及其制备方法和用途
|
|
PE20161065A1
(es)
*
|
2013-10-18 |
2016-11-19 |
Celgene Quanticel Res Inc |
Inhibidores de bromodominio
|
|
WO2015081280A1
(en)
|
2013-11-26 |
2015-06-04 |
Coferon, Inc. |
Bromodomain ligands capable of dimerizing in an aqueous solution
|
|
WO2015081189A1
(en)
|
2013-11-26 |
2015-06-04 |
Incyte Corporation |
Bicyclic heterocycles as bet protein inhibitors
|
|
WO2015081203A1
(en)
|
2013-11-26 |
2015-06-04 |
Incyte Corporation |
Bicyclic heterocycles as bet protein inhibitors
|
|
US20150148372A1
(en)
|
2013-11-26 |
2015-05-28 |
Incyte Corporation |
Bicyclic heterocycles as bet protein inhibitors
|
|
JP2016539970A
(ja)
|
2013-12-09 |
2016-12-22 |
アッヴィ・インコーポレイテッド |
ブロモドメイン阻害薬として有用なジヒドロピリジノンおよびジヒドロピリダジノン誘導体
|
|
EP3080132A4
(en)
|
2013-12-10 |
2017-08-02 |
AbbVie Inc. |
Bromodomain inhibitors
|
|
KR20240134245A
(ko)
|
2014-04-23 |
2024-09-06 |
인사이트 홀딩스 코포레이션 |
BET 단백질의 저해제로서의 1H-피롤로[2,3-c]피리딘-7(6H)-온 및 피라졸로[3,4-c]피리딘-7(6H)-온
|
|
MA40940A
(fr)
|
2014-11-10 |
2017-09-19 |
Constellation Pharmaceuticals Inc |
Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines
|
|
WO2016183114A1
(en)
|
2015-05-11 |
2016-11-17 |
Bristol-Myers Squibb Company |
Tricyclic compounds as anticancer agents
|
|
ES2770349T3
(es)
|
2015-05-12 |
2020-07-01 |
Bristol Myers Squibb Co |
Compuestos de 5H-pirido[3,2-b]indol como agentes antineoplásicos
|
|
JP6606444B2
(ja)
|
2016-03-10 |
2019-11-13 |
株式会社Ｓｕｂａｒｕ |
車両用制御装置
|
|
EP3442977B1
(en)
|
2016-04-15 |
2023-06-28 |
Blueprint Medicines Corporation |
Inhibitors of activin receptor-like kinase
|
|
EP3442962B1
(en)
|
2016-04-15 |
2020-10-28 |
Syngenta Participations AG |
Herbicidal pyridazinone compounds
|
|
KR20230130747A
(ko)
|
2016-04-15 |
2023-09-12 |
에피자임, 인코포레이티드 |
Ehmt1 및 ehmt2 저해제로서의 아민-치환된 아릴 또는 헤테로아릴 화합물
|
|
WO2017177955A1
(en)
*
|
2016-04-15 |
2017-10-19 |
Abbvie Inc. |
Bromodomain inhibitors
|
|
SG11201808214TA
(en)
|
2016-04-15 |
2018-10-30 |
Bayer Animal Health Gmbh |
Pyrazolopyrimidine derivatives
|
|
TW201803594A
(zh)
|
2016-06-09 |
2018-02-01 |
達納-法伯癌症協會 |
Hdac抑制劑與bet抑制劑之使用方法及醫藥組合
|
|
WO2017216772A2
(en)
|
2016-06-16 |
2017-12-21 |
The University Of Chicago |
Methods and compositions for treating breast and prostate cancer
|
|
WO2017223268A1
(en)
|
2016-06-22 |
2017-12-28 |
Yale University |
COMPOSITIONS AND METHODS OF RESENSITIZING CELLS TO BROMODOMAIN AND EXTRATERMINAL DOMAIN PROTEIN INHIBITORS (BETi)
|
|
BR112019007591A2
(pt)
|
2016-10-14 |
2019-07-02 |
Abbvie Inc |
inibidores de bromodomínios
|
|
CA3039003A1
(en)
|
2016-10-14 |
2018-04-19 |
Abbvie Inc. |
Bromodomain inhibitors
|
|
WO2018095933A1
(en)
|
2016-11-22 |
2018-05-31 |
Université D'aix-Marseille (Amu) |
Method of prognosticating, or for determining the efficiency of a compound for treating cancer
|
|
CN110167939B
(zh)
|
2017-01-11 |
2021-12-31 |
江苏豪森药业集团有限公司 |
吡咯并[2,3-c]吡啶类衍生物、其制备方法及其在医药上的应用
|
|
EP3609896A4
(en)
|
2017-04-14 |
2020-11-04 |
AbbVie Inc. |
BROMODOMAIN INHIBITORS
|
|
CN108976278B
(zh)
|
2017-06-05 |
2021-04-06 |
海创药业股份有限公司 |
一种嵌合分子及其制备和应用
|
|
CN108690020A
(zh)
|
2018-07-04 |
2018-10-23 |
清华大学 |
一种靶向降解bet蛋白的化合物及其应用
|