|
US6309640B1
(en)
|
1981-09-08 |
2001-10-30 |
The Rockefeller University |
Lipoprotein lipase suppression by endotoxin-induced mediator (shock assay)
|
|
US4822776A
(en)
|
1981-09-08 |
1989-04-18 |
The Rockefeller University |
Lipoprotein lipase suppression by endotoxin-induced mediator (shock assay)
|
|
US4603106A
(en)
|
1982-02-22 |
1986-07-29 |
The Rockefeller University |
Lipoprotein lipase suppression by endotoxin-induced mediator (shock assay)
|
|
JPS58501544A
(ja)
|
1981-09-08 |
1983-09-16 |
ザ ロツクフエラ− ユニヴア−シテイ |
エンドトキシン誘発メディエ−タ−（ショック検定）によるリポプロティンリパ−ゼの抑圧
|
|
US6419927B1
(en)
|
1981-09-08 |
2002-07-16 |
Anthony Cerami |
Method for reducing adverse effects of a human 70kDa mediator which results from endotoxin stimulation of macrophages
|
|
US5700466A
(en)
|
1981-09-08 |
1997-12-23 |
The Rockefeller University |
Method of ameliorating or preventing septic shock using a monoclonal antibody specific to cachectin/tumor necrosis factor
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
JPS6147500A
(ja)
|
1984-08-15 |
1986-03-07 |
Res Dev Corp Of Japan |
キメラモノクロ−ナル抗体及びその製造法
|
|
JPS61100158A
(ja)
|
1984-10-22 |
1986-05-19 |
Fukuarare Honpo:Kk |
納豆付米菓の製造方法およびその製品
|
|
EP0613006A1
(en)
|
1985-08-16 |
1994-08-31 |
The Rockefeller University |
Antibodies to cachectin and immunoassays
|
|
US4870163A
(en)
|
1985-08-29 |
1989-09-26 |
New York Blood Center, Inc. |
Preparation of pure human tumor necrosis factor and hybridomas producing monoclonal antibodies to human tumor necrosis factor
|
|
DE3631229A1
(de)
|
1986-09-13 |
1988-03-24 |
Basf Ag |
Monoklonale antikoerper gegen humanen tumornekrosefaktor (tnf) und deren verwendung
|
|
EP0832981A1
(en)
|
1987-02-17 |
1998-04-01 |
Pharming B.V. |
DNA sequences to target proteins to the mammary gland for efficient secretion
|
|
JP2647427B2
(ja)
|
1987-04-24 |
1997-08-27 |
帝人株式会社 |
被検者の病態の判定のための検出方法、モノクロ−ナル抗体および検出キット
|
|
US4873316A
(en)
|
1987-06-23 |
1989-10-10 |
Biogen, Inc. |
Isolation of exogenous recombinant proteins from the milk of transgenic mammals
|
|
IL98078A0
(en)
|
1991-05-07 |
1992-06-21 |
Yeda Res & Dev |
Pharmaceutical compositions comprising an anticytokyne
|
|
IL83878A
(en)
|
1987-09-13 |
1995-07-31 |
Yeda Res & Dev |
Soluble protein corresponding to tnf inhibitory protein its preparation and pharmaceutical compositions containing it
|
|
GB8805792D0
(en)
|
1988-03-11 |
1988-04-13 |
Celltech Ltd |
Medicaments
|
|
DE3823804A1
(de)
|
1988-07-14 |
1990-01-18 |
Basf Ag |
Neutralisation der in vitro und in vivo toxischen eigenschaften von tnf-(alpha) durch monoklonale antikoerper und den davon abgeleiteten fragmenten
|
|
NZ229922A
(en)
|
1988-07-18 |
1992-04-28 |
Chiron Corp |
Monoclonal antibodies specifically binding cachectin (tumor necrosis factor) and compositions
|
|
IL94039A
(en)
|
1989-08-06 |
2006-09-05 |
Yeda Res & Dev |
Antibodies to tbp - 1 and their use
|
|
US5360716A
(en)
|
1988-10-24 |
1994-11-01 |
Otsuka Pharmaceutical Co., Ltd. |
Human tumor necrosis factor αspecific monoclonal antibody and method for detecting human tumor necrosis factor α
|
|
JPH02227095A
(ja)
|
1988-10-24 |
1990-09-10 |
Otsuka Pharmaceut Co Ltd |
モノクローナル抗体
|
|
US5223395A
(en)
|
1988-12-01 |
1993-06-29 |
Centocor, Inc. |
Immunometric assays for tumor necrosis factor-alpha and methods for preventing the loss of biological activity of tumor necrosis factor-alpha in biological samples
|
|
US5342613A
(en)
|
1988-12-27 |
1994-08-30 |
Health Research Inc. |
Pharmaceutical compositions and use thereof in the treatment of psoriasis
|
|
PT92900A
(pt)
|
1989-01-24 |
1990-07-31 |
|
Sistema de vectores de expressao para a producao de anticorpos monoclonais quimericos
|
|
US4936843A
(en)
|
1989-02-16 |
1990-06-26 |
Ace Orthopedic Manufacturing |
Kirschner wire clamp and tensioner
|
|
DK0393438T3
(da)
|
1989-04-21 |
2005-05-30 |
Amgen Inc |
TNF-receptor, TNF-bindende proteiner og DNAér, der koder herfor
|
|
AU636608B2
(en)
|
1989-05-18 |
1993-05-06 |
Yeda Research And Development Co. Ltd. |
Tumor necrosis factor binding protein II, it's purification and antibodies thereto
|
|
JP3443119B2
(ja)
|
1989-08-07 |
2003-09-02 |
ペプテック リミテッド |
腫瘍壊死因子結合リガンド
|
|
US5959087A
(en)
|
1989-08-07 |
1999-09-28 |
Peptide Technology, Ltd. |
Tumour necrosis factor binding ligands
|
|
GB8921123D0
(en)
|
1989-09-19 |
1989-11-08 |
Millar Ann B |
Treatment of ards
|
|
AU642938B2
(en)
|
1989-12-13 |
1993-11-04 |
Yeda Research And Development Co. Ltd. |
Expression of the recombinant tumor necrosis factor binding protein 1 (TBP-1)
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
WO1996033735A1
(en)
|
1995-04-27 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
DE4037604A1
(de)
|
1990-04-25 |
1991-10-31 |
Bayer Ag |
Verwendung von anti-tnf-antikoerpern als arzneimittel bei der behandlung von ischaemien und deren folgen
|
|
GB9014932D0
(en)
|
1990-07-05 |
1990-08-22 |
Celltech Ltd |
Recombinant dna product and method
|
|
GB9015908D0
(en)
|
1990-07-19 |
1990-09-05 |
Celltech Ltd |
Multivalent immunoglobulin
|
|
GB9022648D0
(en)
|
1990-10-18 |
1990-11-28 |
Charing Cross Sunley Research |
Polypeptide and its use
|
|
US5958413A
(en)
|
1990-11-01 |
1999-09-28 |
Celltech Limited |
Use of antibodies to TNF or fragments derived thereof and xanthine derivatives for combination therapy and compositions therefor
|
|
GB9109645D0
(en)
|
1991-05-03 |
1991-06-26 |
Celltech Ltd |
Recombinant antibodies
|
|
GB9028123D0
(en)
|
1990-12-28 |
1991-02-13 |
Erba Carlo Spa |
Monoclonal antibodies against human tumor necrosis factor alpha
|
|
ES2145744T5
(es)
|
1991-01-18 |
2008-02-01 |
Amgen Inc. |
Procedimientos para tratar las enfermedades inducidas por el factor de necrosis tumoral.
|
|
US5919452A
(en)
|
1991-03-18 |
1999-07-06 |
New York University |
Methods of treating TNFα-mediated disease using chimeric anti-TNF antibodies
|
|
EP1857553A1
(en)
|
1991-03-18 |
2007-11-21 |
New York University |
Monoclonal and chimeric antibodies specific for human tumor necrosis factor
|
|
US6284471B1
(en)
|
1991-03-18 |
2001-09-04 |
New York University Medical Center |
Anti-TNFa antibodies and assays employing anti-TNFa antibodies
|
|
US5656272A
(en)
|
1991-03-18 |
1997-08-12 |
New York University Medical Center |
Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies
|
|
US7192584B2
(en)
|
1991-03-18 |
2007-03-20 |
Centocor, Inc. |
Methods of treating psoriasis with anti-TNF antibodies
|
|
US5698195A
(en)
|
1991-03-18 |
1997-12-16 |
New York University Medical Center |
Methods of treating rheumatoid arthritis using chimeric anti-TNF antibodies
|
|
US6277969B1
(en)
|
1991-03-18 |
2001-08-21 |
New York University |
Anti-TNF antibodies and peptides of human tumor necrosis factor
|
|
ES2196002T3
(es)
|
1991-07-25 |
2003-12-16 |
Idec Pharma Corp |
Anticuerpos recombinantes para terapia humana.
|
|
MX9204374A
(es)
|
1991-07-25 |
1993-03-01 |
Idec Pharma Corp |
Anticuerpo recombinante y metodo para su produccion.
|
|
EP0525570A3
(en)
|
1991-07-31 |
1993-10-06 |
Miles Inc. |
Anti-idiotypic antibodies that mimic tnf
|
|
IL99120A0
(en)
|
1991-08-07 |
1992-07-15 |
Yeda Res & Dev |
Multimers of the soluble forms of tnf receptors,their preparation and pharmaceutical compositions containing them
|
|
NO178839C
(no)
|
1991-11-25 |
1996-06-12 |
Ottestad Nils T |
Strömningsregulator for opprettholdelse av en stabil strömningsmengde av et fluidum
|
|
PT1024191E
(pt)
|
1991-12-02 |
2008-12-22 |
Medical Res Council |
Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
|
|
ES2121907T3
(es)
|
1992-08-28 |
1998-12-16 |
Bayer Ag |
Uso de anticuerpos monoclonales anti-tnf para el tratamiento de meningitis bacterianas.
|
|
CA2146647C
(en)
|
1992-10-08 |
2009-05-05 |
Marc Feldmann |
Treatment of autoimmune and inflammatory disorders
|
|
EP0671936A1
(en)
|
1992-10-15 |
1995-09-20 |
Dana-Farber Cancer Institute, Inc. |
TREATMENT OF INSULIN RESISTANCE IN OBESITY LINKED TYPE II DIABETES USING ANTAGONISTS TO TNF-$g(a) FUNCTION
|
|
GB9225448D0
(en)
|
1992-12-04 |
1993-01-27 |
Erba Carlo Spa |
Improved synthesis of polymer bioactive conjugates
|
|
US5888511A
(en)
|
1993-02-26 |
1999-03-30 |
Advanced Biotherapy Concepts, Inc. |
Treatment of autoimmune diseases, including AIDS
|
|
DE69427928T3
(de)
|
1993-03-05 |
2012-05-10 |
Bayer Healthcare Llc |
Humane monoklonale anti-TNF alpha Antikörper
|
|
SE9302490D0
(sv)
|
1993-07-26 |
1993-07-26 |
Kabi Pharmacia Ab |
New use of old drugs
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
GB9403909D0
(en)
|
1994-03-01 |
1994-04-20 |
Erba Carlo Spa |
Ureido derivatives of naphthalenephosphonic acids and process for their preparation
|
|
US6190691B1
(en)
|
1994-04-12 |
2001-02-20 |
Adolor Corporation |
Methods for treating inflammatory conditions
|
|
FR2728793A1
(fr)
|
1994-12-28 |
1996-07-05 |
Oreal |
Utilisation d'un antagoniste d'histamine, d'un antagoniste d'interleukine 1 et/ou d'un antagoniste de tnf-alpha dans une composition cosmetique, pharmaceutique ou dermatologique et composition obtenue
|
|
MX336813B
(es)
|
1996-02-09 |
2016-02-02 |
Abbvie Biotechnology Ltd |
Anticuerpos humanos que ligan el tnfa humano.
|
|
GB9702088D0
(en)
|
1997-01-31 |
1997-03-19 |
Pharmacia & Upjohn Spa |
Matrix metalloproteinase inhibitors
|
|
JPH11127855A
(ja)
|
1997-10-27 |
1999-05-18 |
Japan Energy Corp |
組換え型抗ヒトＴＮＦ−αヒトモノクローナル抗体
|
|
UA81743C2
(uk)
|
2000-08-07 |
2008-02-11 |
Центокор, Инк. |
МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
|
|
TWI334439B
(en)
|
2001-08-01 |
2010-12-11 |
Centocor Inc |
Anti-tnf antibodies, compositions, methods and uses
|
|
AU2003225976A1
(en)
|
2002-03-26 |
2003-10-13 |
Centocor, Inc. |
Anti-tnf antibodies, compositions, methods and uses
|
|
WO2004009776A2
(en)
*
|
2002-07-19 |
2004-01-29 |
Abbott Biotechnology Ltd. |
TREATMENT OF TNFα RELATED DISORDERS
|
|
TW201705980A
(zh)
*
|
2004-04-09 |
2017-02-16 |
艾伯維生物技術有限責任公司 |
用於治療ＴＮＦα相關失調症之多重可變劑量療法
|
|
US8188223B2
(en)
*
|
2005-05-18 |
2012-05-29 |
Ablynx N.V. |
Serum albumin binding proteins
|
|
WO2007028106A2
(en)
|
2005-08-31 |
2007-03-08 |
Centocor, Inc. |
Host cell lines for production of antibody constant region with enhanced effector function
|
|
WO2011017294A1
(en)
*
|
2009-08-07 |
2011-02-10 |
Schering Corporation |
Human anti-rankl antibodies
|
|
DK2621282T3
(da)
*
|
2010-09-28 |
2020-05-04 |
Univ California |
Gaba-agonister i behandlingen af forstyrrelser forbundet med metabolisk syndrom og gaba-kombinationer i behandling eller profylakse af type i diabetes
|
|
AU2014224174B2
(en)
*
|
2013-03-06 |
2018-08-30 |
Hadasit Medical Research Services And Development Ltd. |
Use of plant cells expressing a TNFalpha polypeptide inhibitor in therapy
|