JP2016535020A5 - - Google Patents
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- Publication number
- JP2016535020A5 JP2016535020A5 JP2016525876A JP2016525876A JP2016535020A5 JP 2016535020 A5 JP2016535020 A5 JP 2016535020A5 JP 2016525876 A JP2016525876 A JP 2016525876A JP 2016525876 A JP2016525876 A JP 2016525876A JP 2016535020 A5 JP2016535020 A5 JP 2016535020A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- chain variable
- variable region
- seq
- cdr2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019024364A JP6896781B2 (ja) | 2013-10-24 | 2019-02-14 | 安定した水性抗体製剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361895143P | 2013-10-24 | 2013-10-24 | |
| US61/895,143 | 2013-10-24 | ||
| PCT/US2014/061997 WO2015061584A1 (en) | 2013-10-24 | 2014-10-23 | Stable, aqueous antibody formulations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019024364A Division JP6896781B2 (ja) | 2013-10-24 | 2019-02-14 | 安定した水性抗体製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016535020A JP2016535020A (ja) | 2016-11-10 |
| JP2016535020A5 true JP2016535020A5 (https=) | 2017-11-24 |
| JP6483673B2 JP6483673B2 (ja) | 2019-03-13 |
Family
ID=52993565
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016525876A Active JP6483673B2 (ja) | 2013-10-24 | 2014-10-23 | 安定した水性抗体製剤 |
| JP2019024364A Active JP6896781B2 (ja) | 2013-10-24 | 2019-02-14 | 安定した水性抗体製剤 |
| JP2021096239A Pending JP2021152034A (ja) | 2013-10-24 | 2021-06-09 | 安定した水性抗体製剤 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019024364A Active JP6896781B2 (ja) | 2013-10-24 | 2019-02-14 | 安定した水性抗体製剤 |
| JP2021096239A Pending JP2021152034A (ja) | 2013-10-24 | 2021-06-09 | 安定した水性抗体製剤 |
Country Status (23)
| Country | Link |
|---|---|
| US (4) | US20150118249A1 (https=) |
| EP (2) | EP3060229B1 (https=) |
| JP (3) | JP6483673B2 (https=) |
| KR (3) | KR20210041101A (https=) |
| CN (4) | CN105611938B (https=) |
| AU (4) | AU2014339984B2 (https=) |
| BR (1) | BR112016008576B1 (https=) |
| CA (1) | CA2926089C (https=) |
| CY (1) | CY1125697T1 (https=) |
| DK (1) | DK3060229T3 (https=) |
| ES (1) | ES2893861T3 (https=) |
| HR (1) | HRP20211371T1 (https=) |
| HU (1) | HUE055919T2 (https=) |
| LT (1) | LT3060229T (https=) |
| MX (2) | MX388893B (https=) |
| PL (1) | PL3060229T3 (https=) |
| PT (1) | PT3060229T (https=) |
| RS (1) | RS62419B1 (https=) |
| RU (2) | RU2763787C2 (https=) |
| SG (2) | SG10201803178UA (https=) |
| SI (1) | SI3060229T1 (https=) |
| SM (1) | SMT202100580T1 (https=) |
| WO (1) | WO2015061584A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0611901A2 (pt) | 2005-06-14 | 2012-08-28 | Amgen, Inc | composição, liofilizado, kit, e, processo para preparar uma composição |
| US9159537B2 (en) * | 2012-05-03 | 2015-10-13 | University Of Notre Dame Du Lac | Method for analyzing sample components |
| TWI595007B (zh) | 2012-09-10 | 2017-08-11 | Neotope Biosciences Ltd | 抗ｍｃａｍ抗體及相關使用方法 |
| CA2926089C (en) * | 2013-10-24 | 2022-08-30 | Medimmune, Llc | Stable, aqueous antibody formulations |
| PT3116911T (pt) | 2014-03-12 | 2019-09-04 | Prothena Biosciences Ltd | Anticorpos anti-mcam e métodos de utilização associados |
| JP2017514458A (ja) | 2014-03-12 | 2017-06-08 | プロセナ バイオサイエンシーズ リミテッド | Ｌｇ４−５に対して特異的な抗−ラミニン４抗体 |
| EP3350226A2 (en) * | 2015-09-16 | 2018-07-25 | Prothena Biosciences Limited | Use of anti-mcam antibodies for treatment or prophylaxis of giant cell arteritis, polymyalgia rheumatica or takayasu's arteritis |
| EP3383435A4 (en) * | 2015-11-30 | 2019-07-10 | Medimmune, LLC | OPTIMIZED RATES OF AMINO ACIDS AND SUGARS AS AMORPHOUS STABILIZING COMPOUNDS IN PHARMACEUTICAL COMPOSITIONS HAVING HIGH CONCENTRATIONS IN PROTEIN-BASED THERAPEUTICS |
| CN109803640B (zh) | 2016-08-10 | 2022-01-04 | 赛特瑞恩股份有限公司 | 稳定的液体抗流感病毒抗体医药调配物 |
| PT3528787T (pt) | 2016-10-21 | 2026-03-11 | Amgen Inc | Formulações farmacêuticas e métodos para produzir as mesmas |
| ES2991988T3 (es) | 2017-10-30 | 2024-12-05 | Takeda Pharmaceuticals Co | Detergentes compatibles con el medio ambiente para la inactivación de virus con envoltura lipídica |
| CN119264211A (zh) | 2018-08-27 | 2025-01-07 | 瑞泽恩制药公司 | 拉曼光谱在下游纯化中的应用 |
| CN120241997A (zh) | 2019-02-18 | 2025-07-04 | 伊莱利利公司 | 治疗性抗体制剂 |
| AU2020251627A1 (en) * | 2019-03-29 | 2021-11-11 | Jiangsu Hengrui Medicine Co., Ltd. | Pharmaceutical composition containing antibody against IL-5 and use thereof |
| TW202126688A (zh) | 2019-09-27 | 2021-07-16 | 瑞典商阿斯特捷利康公司 | 使用貝那利珠單抗治療遲發性氣喘之方法 |
| WO2021124793A1 (ja) * | 2019-12-16 | 2021-06-24 | ニプロ株式会社 | 凝集防止剤ならびにそれを用いた医薬組成物および医療用デバイス |
| CN111024963A (zh) * | 2019-12-27 | 2020-04-17 | 桂林英美特生物技术研究所 | 一种液体稳定、抗冰冻的免疫比浊法载脂蛋白b单试剂 |
| EP4119161A4 (en) * | 2020-03-13 | 2024-05-15 | Samsung Bioepis Co., Ltd. | Liquid pharmaceutical composition having improved stability |
| CN113769081A (zh) * | 2020-06-10 | 2021-12-10 | 三生国健药业（上海）股份有限公司 | 一种稳定的高浓度抗人il-5单克隆抗体液体制剂 |
| CN116194473A (zh) * | 2020-07-28 | 2023-05-30 | 中外制药株式会社 | 包含新改造型抗体的具备针护罩的带针预充注射器制剂 |
| US20220193238A1 (en) * | 2020-12-17 | 2022-06-23 | Astrazeneca Ab | Anti-il5r antibody formulations |
| WO2026027944A1 (en) * | 2024-07-30 | 2026-02-05 | Sairopa B.V. | Anti-sirp alpha antibody formulations and uses thereof |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU631802B2 (en) | 1988-06-14 | 1992-12-10 | Cetus Oncology Corporation | Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| IE63847B1 (en) | 1989-05-05 | 1995-06-14 | Res Dev Foundation | A novel antibody delivery system for biological response modifiers |
| DE69120146T2 (de) | 1990-01-12 | 1996-12-12 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| US5314995A (en) | 1990-01-22 | 1994-05-24 | Oncogen | Therapeutic interleukin-2-antibody based fusion proteins |
| WO1991014438A1 (en) | 1990-03-20 | 1991-10-03 | The Trustees Of Columbia University In The City Of New York | Chimeric antibodies with receptor binding ligands in place of their constant region |
| DE69133036T2 (de) | 1990-11-09 | 2003-02-06 | Stephen D. Gillies | Cytokine immunokonjugate |
| ES2434840T3 (es) | 1995-07-27 | 2013-12-17 | Genentech, Inc. | Formulación de proteína liofilizada isotónica estable |
| US6267958B1 (en) * | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| ES2233974T3 (es) * | 1995-09-11 | 2005-06-16 | Kyowa Hakko Kogyo Co., Ltd. | Anticuerpo contra la cadena alfa del receptor de la interleucina 5 humana. |
| US6171586B1 (en) | 1997-06-13 | 2001-01-09 | Genentech, Inc. | Antibody formulation |
| CA2704600C (en) | 1999-04-09 | 2016-10-25 | Kyowa Kirin Co., Ltd. | A method for producing antibodies with increased adcc activity |
| US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
| CN1703233A (zh) * | 2002-07-12 | 2005-11-30 | 米德列斯公司 | 防止蛋白氧化降解的方法和组合物 |
| RU2314130C2 (ru) * | 2003-05-26 | 2008-01-10 | Воо Ин БАИК | Одноразовый шприц |
| JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| DE202006001995U1 (de) * | 2006-02-07 | 2006-06-08 | Sarstedt Ag & Co. | Probengefäß zur Aufnahme von kleinen Flüssigkeitsmengen für Analysen |
| AR060487A1 (es) * | 2006-04-21 | 2008-06-18 | Xoma Technology Ltd | Composiciones farmaceuticas de antagonistas del anticuerpo anti- cd40 |
| CN101541345A (zh) * | 2006-09-25 | 2009-09-23 | 米迪缪尼有限公司 | 稳定化的抗体制剂和其应用 |
| CA2682292A1 (en) * | 2007-03-30 | 2008-10-09 | Medimmune, Llc | Aqueous formulation comprising an anti-human interferon alpha antibody |
| MX376656B (es) * | 2007-05-14 | 2025-03-07 | Kyowa Kirin Co Ltd | Metodos para reducir niveles de basófilos. |
| BRPI0820819B1 (pt) | 2007-12-21 | 2021-06-08 | F. Hoffmann-La Roche Ag | formulação de anticorpos humanizados b-ly 1 e seu uso |
| ES2531385T3 (es) * | 2008-09-19 | 2015-03-13 | Hoffmann La Roche | Formulación que comprende un anticuerpo contra la selectina P |
| AU2010221156A1 (en) * | 2009-03-06 | 2011-09-22 | Genentech, Inc. | Antibody formulation |
| US20100278822A1 (en) * | 2009-05-04 | 2010-11-04 | Abbott Biotechnology, Ltd. | Stable high protein concentration formulations of human anti-tnf-alpha-antibodies |
| JOP20190250A1 (ar) | 2010-07-14 | 2017-06-16 | Regeneron Pharma | صيغ مستقرة تحتوي على الأجسام المضادة لمضاد عامل نمو الأعصاب |
| AR087305A1 (es) * | 2011-07-28 | 2014-03-12 | Regeneron Pharma | Formulaciones estabilizadas que contienen anticuerpos anti-pcsk9, metodo de preparacion y kit |
| BR112014009146A8 (pt) * | 2011-10-18 | 2017-06-20 | Coherus Biosciences Inc | formulações de etanercepte estabilizadas com aminoácidos |
| US20130109807A1 (en) * | 2011-10-26 | 2013-05-02 | Bio-Rad Laboratories, Inc. | Removal of virucidal agents in mixed mode chromatography |
| CN108771655A (zh) * | 2011-10-28 | 2018-11-09 | 诚信生物公司 | 含有氨基酸的蛋白质制剂 |
| US20140328839A1 (en) * | 2011-11-01 | 2014-11-06 | Medlmmune, Llc | Methods For Reducing The Frequency And Severity Of Acute Exacerbations Of Asthma |
| AR090244A1 (es) | 2012-03-08 | 2014-10-29 | Hoffmann La Roche | Formulacion de anticuerpo anti-selectina p |
| US9216219B2 (en) | 2012-06-12 | 2015-12-22 | Novartis Ag | Anti-BAFFR antibody formulation |
| RU2728578C2 (ru) | 2013-08-12 | 2020-07-30 | Астразенека Аб | Способы нормализации симптомов астмы с применением бенрализумаба |
| AU2014306956B2 (en) | 2013-08-12 | 2019-11-21 | Astrazeneca Ab | Methods for reducing exacerbation rates of asthma using benralizumab |
| SMT202100152T1 (it) * | 2013-08-12 | 2021-05-07 | Astrazeneca Ab | Metodi per aumentare il volume espiratorio forzato negli asmatici utilizzando benralizumab |
| CA2926089C (en) * | 2013-10-24 | 2022-08-30 | Medimmune, Llc | Stable, aqueous antibody formulations |
-
2014
- 2014-10-23 CA CA2926089A patent/CA2926089C/en active Active
- 2014-10-23 MX MX2016004605A patent/MX388893B/es unknown
- 2014-10-23 JP JP2016525876A patent/JP6483673B2/ja active Active
- 2014-10-23 EP EP14855343.1A patent/EP3060229B1/en active Active
- 2014-10-23 CN CN201480055263.0A patent/CN105611938B/zh active Active
- 2014-10-23 KR KR1020217009731A patent/KR20210041101A/ko not_active Ceased
- 2014-10-23 RU RU2016119755A patent/RU2763787C2/ru active
- 2014-10-23 CN CN202110799711.XA patent/CN113350278B/zh active Active
- 2014-10-23 HU HUE14855343A patent/HUE055919T2/hu unknown
- 2014-10-23 PT PT14855343T patent/PT3060229T/pt unknown
- 2014-10-23 RU RU2021137159A patent/RU2021137159A/ru unknown
- 2014-10-23 SI SI201431876T patent/SI3060229T1/sl unknown
- 2014-10-23 KR KR1020167012565A patent/KR102109053B1/ko active Active
- 2014-10-23 SM SM20210580T patent/SMT202100580T1/it unknown
- 2014-10-23 DK DK14855343.1T patent/DK3060229T3/da active
- 2014-10-23 PL PL14855343T patent/PL3060229T3/pl unknown
- 2014-10-23 LT LTEPPCT/US2014/061997T patent/LT3060229T/lt unknown
- 2014-10-23 AU AU2014339984A patent/AU2014339984B2/en active Active
- 2014-10-23 CN CN202010809794.1A patent/CN112107538A/zh active Pending
- 2014-10-23 HR HRP20211371TT patent/HRP20211371T1/hr unknown
- 2014-10-23 CN CN202411964617.5A patent/CN119971024A/zh active Pending
- 2014-10-23 BR BR112016008576-0A patent/BR112016008576B1/pt active IP Right Grant
- 2014-10-23 SG SG10201803178UA patent/SG10201803178UA/en unknown
- 2014-10-23 RS RS20211238A patent/RS62419B1/sr unknown
- 2014-10-23 EP EP20207556.0A patent/EP3892288A1/en active Pending
- 2014-10-23 WO PCT/US2014/061997 patent/WO2015061584A1/en not_active Ceased
- 2014-10-23 ES ES14855343T patent/ES2893861T3/es active Active
- 2014-10-23 US US14/521,870 patent/US20150118249A1/en not_active Abandoned
- 2014-10-23 KR KR1020207012828A patent/KR102238065B1/ko active Active
- 2014-10-23 SG SG11201603206UA patent/SG11201603206UA/en unknown
-
2016
- 2016-04-11 MX MX2021015825A patent/MX2021015825A/es unknown
-
2019
- 2019-02-14 JP JP2019024364A patent/JP6896781B2/ja active Active
- 2019-03-11 US US16/298,474 patent/US12582716B2/en active Active
-
2020
- 2020-03-25 US US16/829,659 patent/US20200297855A1/en not_active Abandoned
- 2020-07-09 AU AU2020204608A patent/AU2020204608A1/en not_active Abandoned
-
2021
- 2021-06-09 JP JP2021096239A patent/JP2021152034A/ja active Pending
- 2021-10-19 CY CY20211100902T patent/CY1125697T1/el unknown
-
2022
- 2022-12-23 AU AU2022291595A patent/AU2022291595B2/en active Active
-
2025
- 2025-02-04 US US19/045,166 patent/US20250170245A1/en active Pending
- 2025-09-12 AU AU2025230794A patent/AU2025230794A1/en active Pending
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