JP2019509015A5 - - Google Patents
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- JP2019509015A5 JP2019509015A5 JP2018530698A JP2018530698A JP2019509015A5 JP 2019509015 A5 JP2019509015 A5 JP 2019509015A5 JP 2018530698 A JP2018530698 A JP 2018530698A JP 2018530698 A JP2018530698 A JP 2018530698A JP 2019509015 A5 JP2019509015 A5 JP 2019509015A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- adapter
- target nucleic
- strand
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 150000007523 nucleic acids Chemical class 0.000 claims 51
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 24
- 238000000034 method Methods 0.000 claims 24
- 108020004707 nucleic acids Proteins 0.000 claims 19
- 102000039446 nucleic acids Human genes 0.000 claims 19
- 108091035707 Consensus sequence Proteins 0.000 claims 9
- 239000007801 affinity label Substances 0.000 claims 9
- 239000002773 nucleotide Substances 0.000 claims 9
- 125000003729 nucleotide group Chemical group 0.000 claims 9
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 8
- 229960002685 biotin Drugs 0.000 claims 6
- 239000011616 biotin Substances 0.000 claims 6
- 238000012163 sequencing technique Methods 0.000 claims 5
- 235000020958 biotin Nutrition 0.000 claims 4
- 230000000295 complement effect Effects 0.000 claims 4
- 102000005720 Glutathione transferase Human genes 0.000 claims 2
- 108010070675 Glutathione transferase Proteins 0.000 claims 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 239000001226 triphosphate Substances 0.000 claims 2
- 108010073254 Colicins Proteins 0.000 claims 1
- 108020004414 DNA Proteins 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 108091093037 Peptide nucleic acid Proteins 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- 230000003321 amplification Effects 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- 238000007865 diluting Methods 0.000 claims 1
- 230000005684 electric field Effects 0.000 claims 1
- 229910052759 nickel Inorganic materials 0.000 claims 1
- 238000003199 nucleic acid amplification method Methods 0.000 claims 1
- 235000021317 phosphate Nutrition 0.000 claims 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 claims 1
- 230000001376 precipitating effect Effects 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 150000003384 small molecules Chemical class 0.000 claims 1
- 230000001502 supplementing effect Effects 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021179334A JP7548579B2 (ja) | 2015-12-08 | 2021-11-02 | 二本鎖配列決定のための改善されたアダプター、方法、及び組成物 |
| JP2023184524A JP2024010122A (ja) | 2015-12-08 | 2023-10-27 | 二本鎖配列決定のための改善されたアダプター、方法、及び組成物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562264822P | 2015-12-08 | 2015-12-08 | |
| US62/264,822 | 2015-12-08 | ||
| US201662281917P | 2016-01-22 | 2016-01-22 | |
| US62/281,917 | 2016-01-22 | ||
| PCT/US2016/065605 WO2017100441A1 (en) | 2015-12-08 | 2016-12-08 | Improved adapters, methods, and compositions for duplex sequencing |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021179334A Division JP7548579B2 (ja) | 2015-12-08 | 2021-11-02 | 二本鎖配列決定のための改善されたアダプター、方法、及び組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019509015A JP2019509015A (ja) | 2019-04-04 |
| JP2019509015A5 true JP2019509015A5 (enExample) | 2020-01-23 |
| JP6975507B2 JP6975507B2 (ja) | 2021-12-01 |
Family
ID=57750605
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018530698A Active JP6975507B2 (ja) | 2015-12-08 | 2016-12-08 | 二本鎖配列決定のための改善されたアダプター、方法、及び組成物 |
| JP2021179334A Active JP7548579B2 (ja) | 2015-12-08 | 2021-11-02 | 二本鎖配列決定のための改善されたアダプター、方法、及び組成物 |
| JP2023184524A Pending JP2024010122A (ja) | 2015-12-08 | 2023-10-27 | 二本鎖配列決定のための改善されたアダプター、方法、及び組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021179334A Active JP7548579B2 (ja) | 2015-12-08 | 2021-11-02 | 二本鎖配列決定のための改善されたアダプター、方法、及び組成物 |
| JP2023184524A Pending JP2024010122A (ja) | 2015-12-08 | 2023-10-27 | 二本鎖配列決定のための改善されたアダプター、方法、及び組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11332784B2 (enExample) |
| EP (2) | EP3387152B1 (enExample) |
| JP (3) | JP6975507B2 (enExample) |
| CN (1) | CN109072294A (enExample) |
| AU (1) | AU2016366231B2 (enExample) |
| CA (1) | CA3006792A1 (enExample) |
| ES (1) | ES2911421T3 (enExample) |
| IL (1) | IL259788B2 (enExample) |
| PL (1) | PL3387152T3 (enExample) |
| PT (1) | PT3387152T (enExample) |
| WO (1) | WO2017100441A1 (enExample) |
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- 2016-12-08 CN CN201680080120.4A patent/CN109072294A/zh active Pending
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