JP2019505521A5 - - Google Patents
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- Publication number
- JP2019505521A5 JP2019505521A5 JP2018536444A JP2018536444A JP2019505521A5 JP 2019505521 A5 JP2019505521 A5 JP 2019505521A5 JP 2018536444 A JP2018536444 A JP 2018536444A JP 2018536444 A JP2018536444 A JP 2018536444A JP 2019505521 A5 JP2019505521 A5 JP 2019505521A5
- Authority
- JP
- Japan
- Prior art keywords
- egf
- seq
- formula
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 12
- 125000003275 alpha amino acid group Chemical group 0.000 claims 10
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2016070791 | 2016-01-13 | ||
| CNPCT/CN2016/070791 | 2016-01-13 | ||
| CN2016076580 | 2016-03-17 | ||
| CNPCT/CN2016/076580 | 2016-03-17 | ||
| EP16195965 | 2016-10-27 | ||
| EP16195965.5 | 2016-10-27 | ||
| PCT/EP2017/050668 WO2017121850A1 (en) | 2016-01-13 | 2017-01-13 | Egf(a) analogues with fatty acid substituents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020190846A Division JP2021035989A (ja) | 2016-01-13 | 2020-11-17 | 脂肪酸置換基を有するｅｇｆ（ａ）類似体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019505521A JP2019505521A (ja) | 2019-02-28 |
| JP2019505521A5 true JP2019505521A5 (enExample) | 2020-06-18 |
| JP6797926B2 JP6797926B2 (ja) | 2020-12-09 |
Family
ID=57868232
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018536444A Active JP6797926B2 (ja) | 2016-01-13 | 2017-01-13 | 脂肪酸置換基を有するｅｇｆ（ａ）類似体 |
| JP2020190846A Withdrawn JP2021035989A (ja) | 2016-01-13 | 2020-11-17 | 脂肪酸置換基を有するｅｇｆ（ａ）類似体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020190846A Withdrawn JP2021035989A (ja) | 2016-01-13 | 2020-11-17 | 脂肪酸置換基を有するｅｇｆ（ａ）類似体 |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US10822385B2 (enExample) |
| EP (1) | EP3402811B1 (enExample) |
| JP (2) | JP6797926B2 (enExample) |
| KR (1) | KR102417487B1 (enExample) |
| CN (1) | CN108473550B (enExample) |
| AU (1) | AU2017207862B2 (enExample) |
| BR (1) | BR112018013820A2 (enExample) |
| CA (1) | CA3010756A1 (enExample) |
| CL (1) | CL2018001868A1 (enExample) |
| CO (1) | CO2018007440A2 (enExample) |
| DK (1) | DK3402811T3 (enExample) |
| ES (1) | ES2916998T3 (enExample) |
| HR (1) | HRP20220720T1 (enExample) |
| HU (1) | HUE058647T2 (enExample) |
| IL (1) | IL260043A (enExample) |
| LT (1) | LT3402811T (enExample) |
| MX (1) | MX2018008681A (enExample) |
| MY (1) | MY195199A (enExample) |
| PE (1) | PE20181376A1 (enExample) |
| PH (1) | PH12018501502A1 (enExample) |
| PL (1) | PL3402811T3 (enExample) |
| RS (1) | RS63298B1 (enExample) |
| RU (1) | RU2747877C2 (enExample) |
| SA (1) | SA518391996B1 (enExample) |
| SI (1) | SI3402811T1 (enExample) |
| WO (1) | WO2017121850A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20221732A1 (es) | 2016-01-13 | 2022-11-07 | Gruenenthal Chemie | Derivados de 3-((hetero)aril)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano |
| BR112018014301B1 (pt) | 2016-01-13 | 2023-10-31 | Grünenthal GmbH | Derivados de 8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano |
| ES2797904T3 (es) | 2016-01-13 | 2020-12-04 | Gruenenthal Gmbh | Derivados de 3-((hetero)aril)alquil-8-amino-2-oxo-1,3-diazaespiro-[4.5]-decano |
| WO2017121649A1 (en) | 2016-01-13 | 2017-07-20 | Grünenthal GmbH | 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives |
| RS63298B1 (sr) | 2016-01-13 | 2022-07-29 | Novo Nordisk As | Egf(a) analozi sa supstituentima masnih kiselina |
| CN111164098A (zh) * | 2017-07-19 | 2020-05-15 | 诺沃挪第克公司 | Egf(a)类似物、其制品、制剂和用途 |
| CA3068956A1 (en) | 2017-07-19 | 2019-01-24 | Novo Nordisk A/S | Bifunctional compounds |
| WO2019023295A1 (en) * | 2017-07-27 | 2019-01-31 | Saint Louis University | Fatty acid modified human epidermal growth factor |
| JOP20190150A1 (ar) | 2018-06-21 | 2019-12-21 | Merck Sharp & Dohme | مركبات مناهضة لـ pcsk9 |
| CN112789289A (zh) * | 2018-10-05 | 2021-05-11 | 诺和诺德股份有限公司 | 包含胰岛素肽和egf(a)肽的双功能化合物 |
| MX2021010767A (es) | 2019-03-22 | 2021-09-28 | 3M Innovative Properties Company | Sistema de proteccion contra caidas con sistema de monitoreo. |
| CN110357969B (zh) * | 2019-05-27 | 2022-03-08 | 北京志道生物科技有限公司 | 一种GLP1-EGFa异源二聚体蛋白、功能及方法 |
| EP4009958A1 (en) | 2019-08-07 | 2022-06-15 | Novo Nordisk A/S | Solid compositions comprising an egf(a) derivative and a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid |
| WO2021089761A1 (en) | 2019-11-07 | 2021-05-14 | Novo Nordisk A/S | Solid compositions comprising a pcsk9 inhibitor and a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid |
| US12428278B2 (en) | 2021-07-02 | 2025-09-30 | 3M Innovative Properties Company | Aerial lift interlocked with fall-protection safety apparatus |
| WO2023012263A1 (en) | 2021-08-04 | 2023-02-09 | Novo Nordisk A/S | Solid oral peptide formulations |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006279276A1 (en) | 2005-07-29 | 2007-02-15 | Amprotein Corporation | Chimeric therapeutic agents |
| AU2006279680B2 (en) | 2005-08-11 | 2012-12-06 | Amylin Pharmaceuticals, Llc | Hybrid polypeptides with selectable properties |
| EP2178910B1 (en) * | 2007-08-15 | 2014-10-08 | Novo Nordisk A/S | Insulins with an acyl moiety comprising repeating units of alkylene glycol containing amino acids |
| JP5806110B2 (ja) | 2008-04-23 | 2015-11-10 | アムジエン・インコーポレーテツド | 中和プロタンパク質コンベルターゼズブチリシンケクシン９型（ｐｃｓｋ９）変形物及びその使用 |
| WO2009143633A1 (en) | 2008-05-30 | 2009-12-03 | Institut De Recherches Cliniques De Montreal | Pcsk9 inhibitors and methods of use thereof |
| TWI445716B (zh) | 2008-09-12 | 2014-07-21 | Rinat Neuroscience Corp | Ｐｃｓｋ９拮抗劑類 |
| CN101993485B (zh) | 2009-08-20 | 2013-04-17 | 重庆富进生物医药有限公司 | 促胰岛素分泌肽类似物同源二聚体及其用途 |
| US8939592B2 (en) | 2010-08-02 | 2015-01-27 | Nec Corporation | Polarizer and light-emitting device |
| CN102153652A (zh) | 2010-12-10 | 2011-08-17 | 浙江大学 | 一种融合蛋白的表达方法及用途 |
| CN103370075A (zh) | 2011-02-15 | 2013-10-23 | 诺沃—诺迪斯克有限公司 | 长效il-1受体拮抗剂 |
| RU2014101501A (ru) * | 2011-06-20 | 2015-07-27 | Дженентек, Инк. | Связывающие pcsk9 полипептиды и способы применения |
| CN104093735B (zh) * | 2011-09-23 | 2018-07-06 | 诺沃—诺迪斯克有限公司 | 新的胰高血糖素类似物 |
| US9458214B2 (en) | 2011-09-26 | 2016-10-04 | Novartis Ag | Dual function fibroblast growth factor 21 proteins |
| JP2015502971A (ja) * | 2011-12-21 | 2015-01-29 | ノヴォ ノルディスク アー／エス | Ｎ末端修飾インスリン誘導体 |
| EP2851429B1 (en) | 2012-05-18 | 2019-07-24 | Adda Biotech Inc. | Protein and protein conjugate for diabetes treatment, and applications thereof |
| TW201420606A (zh) | 2012-08-22 | 2014-06-01 | Lilly Co Eli | 同源二聚體蛋白 |
| HK1207097A1 (en) | 2012-09-07 | 2016-01-22 | Sanofi | Fusion proteins for treating a metabolic syndrome |
| MY174727A (en) * | 2013-04-18 | 2020-05-11 | Novo Nordisk As | Stable, protracted glp-1/glucagon receptor co-agonists for medical use |
| WO2015051214A1 (en) | 2013-10-03 | 2015-04-09 | Moderna Therapeutics, Inc. | Polynucleotides encoding low density lipoprotein receptor |
| BR112016017402A2 (pt) | 2014-02-21 | 2017-10-17 | Medimmune Ltd | fusões anti-pcsk9~glp-1 e métodos para uso |
| EP3151852A1 (en) * | 2014-06-04 | 2017-04-12 | Novo Nordisk A/S | Glp-1/glucagon receptor co-agonists for medical use |
| CN104558198A (zh) | 2014-07-25 | 2015-04-29 | 成都贝爱特生物科技有限公司 | GLP-1类似物和amylin类似物的融合蛋白制备及其用途 |
| EP3271379A4 (en) * | 2015-03-19 | 2018-08-01 | Institut de Cardiologie de Montréal | Grp94 derived polypeptides for inhibiting pcsk9 and methods of use |
| CN105367884A (zh) | 2015-11-02 | 2016-03-02 | 陈薇 | 一种绝缘耐火抗辐射的屏蔽电缆材料及其制备方法 |
| RS63298B1 (sr) | 2016-01-13 | 2022-07-29 | Novo Nordisk As | Egf(a) analozi sa supstituentima masnih kiselina |
| CN111164098A (zh) | 2017-07-19 | 2020-05-15 | 诺沃挪第克公司 | Egf(a)类似物、其制品、制剂和用途 |
| CA3068956A1 (en) | 2017-07-19 | 2019-01-24 | Novo Nordisk A/S | Bifunctional compounds |
-
2017
- 2017-01-13 RS RS20220538A patent/RS63298B1/sr unknown
- 2017-01-13 US US16/069,932 patent/US10822385B2/en active Active
- 2017-01-13 CN CN201780006783.6A patent/CN108473550B/zh active Active
- 2017-01-13 MY MYPI2018702319A patent/MY195199A/en unknown
- 2017-01-13 LT LTEPPCT/EP2017/050668T patent/LT3402811T/lt unknown
- 2017-01-13 CA CA3010756A patent/CA3010756A1/en not_active Withdrawn
- 2017-01-13 ES ES17701078T patent/ES2916998T3/es active Active
- 2017-01-13 KR KR1020187022105A patent/KR102417487B1/ko active Active
- 2017-01-13 AU AU2017207862A patent/AU2017207862B2/en not_active Ceased
- 2017-01-13 DK DK17701078.2T patent/DK3402811T3/da active
- 2017-01-13 HR HRP20220720TT patent/HRP20220720T1/hr unknown
- 2017-01-13 PE PE2018001257A patent/PE20181376A1/es unknown
- 2017-01-13 JP JP2018536444A patent/JP6797926B2/ja active Active
- 2017-01-13 EP EP17701078.2A patent/EP3402811B1/en active Active
- 2017-01-13 WO PCT/EP2017/050668 patent/WO2017121850A1/en not_active Ceased
- 2017-01-13 SI SI201731149T patent/SI3402811T1/sl unknown
- 2017-01-13 BR BR112018013820-7A patent/BR112018013820A2/pt not_active Application Discontinuation
- 2017-01-13 RU RU2018127882A patent/RU2747877C2/ru active
- 2017-01-13 HU HUE17701078A patent/HUE058647T2/hu unknown
- 2017-01-13 PL PL17701078T patent/PL3402811T3/pl unknown
- 2017-01-13 MX MX2018008681A patent/MX2018008681A/es unknown
-
2018
- 2018-06-14 IL IL260043A patent/IL260043A/en unknown
- 2018-07-09 CL CL2018001868A patent/CL2018001868A1/es unknown
- 2018-07-10 SA SA518391996A patent/SA518391996B1/ar unknown
- 2018-07-12 PH PH12018501502A patent/PH12018501502A1/en unknown
- 2018-07-16 CO CONC2018/0007440A patent/CO2018007440A2/es unknown
-
2020
- 2020-09-17 US US17/024,264 patent/US20200407409A1/en not_active Abandoned
- 2020-11-17 JP JP2020190846A patent/JP2021035989A/ja not_active Withdrawn
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