|
CA2979215A1
(en)
|
2015-03-10 |
2016-09-15 |
Aduro Biotech, Inc. |
Compositions and methods for activating "stimulator of interferon gene"-dependent signalling
|
|
MA42608A
(fr)
|
2015-08-13 |
2018-06-20 |
Merck Sharp & Dohme |
Composés de di-nucléotide cyclique en tant qu'agonistes sting (stimulateur de gène interféron)
|
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
KR20250049441A
(ko)
*
|
2016-01-11 |
2025-04-11 |
인네이트 튜머 이뮤니티, 인코포레이티드 |
Sting 활성과 연관된 상태 예컨대 암의 치료를 위한 시클릭 디뉴클레오티드
|
|
EP3429596B1
(en)
|
2016-03-18 |
2022-08-31 |
Immune Sensor, LLC |
Cyclic di-nucleotide compounds and methods of use
|
|
WO2018009466A1
(en)
|
2016-07-05 |
2018-01-11 |
Aduro Biotech, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
|
KR102569881B1
(ko)
|
2016-07-06 |
2023-08-22 |
에프-스타 테라퓨틱스 인코포레이티드 |
질병 치료용 화합물, 조성물 및 방법
|
|
DK3922279T3
(da)
|
2016-08-30 |
2025-02-03 |
Dana Farber Cancer Inst Inc |
Præparater til lægemiddelafgivelse og anvendelse heraf
|
|
RS62410B1
(sr)
|
2016-10-04 |
2021-10-29 |
Merck Sharp & Dohme |
Benzo[b]tiofenska jedinjenja kao agonisti sting
|
|
JOP20170192A1
(ar)
|
2016-12-01 |
2019-01-30 |
Takeda Pharmaceuticals Co |
داي نوكليوتيد حلقي
|
|
US20200055883A1
(en)
|
2017-02-17 |
2020-02-20 |
Eisai R&D Management Co., Ltd. |
Cyclic di-nucleotides derivative for the treatment of cancer
|
|
MX2019012233A
(es)
|
2017-04-13 |
2020-01-14 |
Aduro Biotech Holdings Europe Bv |
Anticuerpos anti-sirpa.
|
|
US11466047B2
(en)
|
2017-05-12 |
2022-10-11 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
US11259980B2
(en)
|
2017-07-31 |
2022-03-01 |
Arizona Board Of Regents On Behalf Of Arizona State University |
Soft inflatable exosuit for knee rehabilitation
|
|
WO2019027857A1
(en)
|
2017-08-04 |
2019-02-07 |
Merck Sharp & Dohme Corp. |
COMBINATIONS OF PD-1 ANTAGONISTS AND STING BENZO [B] THIOPHENIC AGONISTS FOR THE TREATMENT OF CANCER
|
|
JP2020530838A
(ja)
|
2017-08-04 |
2020-10-29 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
がん治療のためのベンゾ[b]チオフェンSTINGアゴニスト
|
|
WO2019043634A2
(en)
|
2017-08-30 |
2019-03-07 |
Beijing Xuanyi Pharmasciences Co., Ltd. |
CYCLIC DI-NUCLEOTIDES AS STIMULATORS OF INTERFERON GENE MODULATORS
|
|
WO2019046511A1
(en)
|
2017-08-31 |
2019-03-07 |
Sperovie Biosciences, Inc. |
COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASE
|
|
WO2019046496A1
(en)
*
|
2017-08-31 |
2019-03-07 |
Bristol-Myers Squibb Company |
CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS
|
|
WO2019051489A1
(en)
|
2017-09-11 |
2019-03-14 |
Sperovie Biosciences, Inc. |
COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISEASE
|
|
US11584774B2
(en)
|
2017-09-11 |
2023-02-21 |
F-star Therapeutics, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
|
AU2018332214B2
(en)
*
|
2017-09-14 |
2023-11-02 |
Janssen Biopharma, Inc. |
Modified nucleoside phosphoramidites
|
|
WO2019074887A1
(en)
*
|
2017-10-10 |
2019-04-18 |
Bristol-Myers Squibb Company |
CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS
|
|
WO2019084060A1
(en)
|
2017-10-24 |
2019-05-02 |
Silverback Therapeutics, Inc. |
CONJUGATES AND METHODS OF USE FOR THE SELECTIVE DELIVERY OF IMMUNOMODULATORY AGENTS
|
|
MX2020004858A
(es)
|
2017-11-10 |
2020-10-01 |
Takeda Pharmaceuticals Co |
Compuestos moduladores de sting y metodos de elaboracion y uso.
|
|
EP3728283B1
(en)
|
2017-12-20 |
2023-11-22 |
Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. |
3'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
|
WO2019125974A1
(en)
|
2017-12-20 |
2019-06-27 |
Merck Sharp & Dohme Corp. |
Cyclic di-nucleotide compounds as sting agonists
|
|
CN111511754B
(zh)
|
2017-12-20 |
2023-09-12 |
捷克共和国有机化学与生物化学研究所 |
活化sting转接蛋白的具有膦酸酯键的2’3’环状二核苷酸
|
|
EP3505527A1
(en)
*
|
2017-12-29 |
2019-07-03 |
Invivogen |
Cyclic dinucleotides for cytokine induction
|
|
US10519187B2
(en)
*
|
2018-02-13 |
2019-12-31 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
|
WO2019173587A1
(en)
*
|
2018-03-08 |
2019-09-12 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
|
US20210015915A1
(en)
|
2018-03-23 |
2021-01-21 |
Takeda Pharmaceutical Company Limited |
Sting modulator compounds with sulfamate linkages, and methods of making and using
|
|
WO2019195063A1
(en)
|
2018-04-03 |
2019-10-10 |
Merck Sharp & Dohme Corp. |
Aza-benzothiophene compounds as sting agonists
|
|
WO2019195124A1
(en)
|
2018-04-03 |
2019-10-10 |
Merck Sharp & Dohme Corp. |
Benzothiophenes and related compounds as sting agonists
|
|
TWI818007B
(zh)
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
|
TWI833744B
(zh)
|
2018-04-06 |
2024-03-01 |
捷克科學院有機化學與生物化學研究所 |
3'3'-環二核苷酸
|
|
US10947227B2
(en)
|
2018-05-25 |
2021-03-16 |
Incyte Corporation |
Tricyclic heterocyclic compounds as sting activators
|
|
US12291548B2
(en)
|
2018-07-10 |
2025-05-06 |
Sperovie Biosciences, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
|
TW202030199A
(zh)
*
|
2018-07-17 |
2020-08-16 |
美商健生生物科技公司 |
作為sting促效劑之環狀二核苷酸
|
|
US11008344B2
(en)
|
2018-07-31 |
2021-05-18 |
Incyte Corporation |
Tricyclic heteroaryl compounds as STING activators
|
|
US10875872B2
(en)
|
2018-07-31 |
2020-12-29 |
Incyte Corporation |
Heteroaryl amide compounds as sting activators
|
|
WO2020036199A1
(en)
|
2018-08-16 |
2020-02-20 |
Eisai R&D Management Co., Ltd. |
Salts of compounds and crystals thereof
|
|
CN118878620A
(zh)
|
2018-09-06 |
2024-11-01 |
第一三共株式会社 |
环状二核苷酸衍生物及抗体药物偶联物的制造方法
|
|
SG11202101980VA
(en)
|
2018-09-12 |
2021-03-30 |
Silverback Therapeutics Inc |
Methods and composition for the treatment of disease with immune stimulatory conjugates
|
|
WO2020057546A1
(zh)
|
2018-09-21 |
2020-03-26 |
上海迪诺医药科技有限公司 |
环状二核苷酸类似物、其药物组合物及应用
|
|
US11110106B2
(en)
|
2018-10-29 |
2021-09-07 |
Venenum Biodesign, LLC |
Sting agonists for treating bladder cancer and solid tumors
|
|
US11161864B2
(en)
|
2018-10-29 |
2021-11-02 |
Venenum Biodesign, LLC |
Sting agonists
|
|
WO2020089815A1
(en)
|
2018-10-31 |
2020-05-07 |
Novartis Ag |
Antibody conjugates comprising sting agonist
|
|
US11596692B1
(en)
|
2018-11-21 |
2023-03-07 |
Incyte Corporation |
PD-L1/STING conjugates and methods of use
|
|
EA202191565A1
(ru)
*
|
2018-12-04 |
2021-12-02 |
Бристол-Маерс Сквибб Компани |
Способ получения циклического динуклеотида
|
|
WO2020146237A1
(en)
|
2019-01-07 |
2020-07-16 |
Incyte Corporation |
Heteroaryl amide compounds as sting activators
|
|
US12060384B2
(en)
|
2019-02-05 |
2024-08-13 |
Bristol-Myers Squibb Company |
Synthesis of 1,2,5-tri-o-benzoyl-3-dibenzylamino-3-deoxyribose as intermediate for producing 3′-amino-3′-deoxyadenosine and 3′-amino-3′-deoxyguanosine and the protected derivatives thereof
|
|
CA3139809A1
(en)
|
2019-05-10 |
2020-11-19 |
Takeda Pharmaceutical Company Limited |
Antibody drug conjugates
|
|
CA3145889A1
(en)
|
2019-07-05 |
2021-01-14 |
Tambo, Inc. |
Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy
|
|
US12435104B2
(en)
*
|
2019-07-25 |
2025-10-07 |
Beigene, Ltd. |
Cyclic dinucleotides as sting agonists
|
|
CA3151322A1
(en)
|
2019-10-01 |
2021-04-08 |
Silverback Therapeutics, Inc. |
Combination therapy with immune stimulatory conjugates
|
|
KR20220122701A
(ko)
|
2019-12-26 |
2022-09-02 |
내셔널 유니버시티 코포레이션 토카이 내셔널 하이어 에듀케이션 앤드 리서치 시스템 |
폴리뉴클레오티드 및 의약 조성물
|
|
EP4106819A1
(en)
|
2020-02-21 |
2022-12-28 |
Silverback Therapeutics, Inc. |
Nectin-4 antibody conjugates and uses thereof
|
|
PH12022551961A1
(en)
|
2020-03-06 |
2023-10-09 |
Daiichi Sankyo Co Ltd |
Antibody-drug conjugate including novel cyclic dinucleotide derivative
|
|
EP4134098A4
(en)
|
2020-04-10 |
2024-05-15 |
ONO Pharmaceutical Co., Ltd. |
Method of cancer therapy
|
|
WO2021216698A1
(en)
*
|
2020-04-21 |
2021-10-28 |
Duke University |
Compositions and methods for the treatment of pain
|
|
WO2021228832A1
(en)
|
2020-05-11 |
2021-11-18 |
Erytech Pharma |
Red cell extracellular vesicles (rcevs) containing cargoes and methods of use and production thereof
|
|
IL299508A
(en)
|
2020-07-01 |
2023-02-01 |
Ars Pharmaceuticals Inc |
Anti-asgr1 antibody conjugates and uses thereof
|
|
CN116056765A
(zh)
|
2020-08-07 |
2023-05-02 |
坦伯公司 |
反式环辛烯生物正交剂及在癌症和免疫疗法中的用途
|
|
AU2021338014A1
(en)
|
2020-09-02 |
2023-03-09 |
Daiichi Sankyo Company, Limited |
Novel endo-β-N-acetylglucosaminidase
|
|
EP4228657A4
(en)
*
|
2020-10-15 |
2024-11-20 |
The Regents Of The University Of Michigan |
Crystalline polymorphic forms of sting agonists associated with metal ions capable of modulating an immune response
|
|
KR102466750B1
(ko)
|
2020-10-23 |
2022-11-15 |
아주대학교산학협력단 |
인돌리진 유도체를 유효성분으로 포함하는 인터페론 유전자 자극제 조성물
|
|
KR20230141754A
(ko)
|
2020-10-30 |
2023-10-10 |
아박타 라이프 사이언시스 리미티드 |
Fap-활성화 혈청 반감기 연장된 치료 접합체
|
|
EP4240488A1
(en)
|
2020-11-09 |
2023-09-13 |
Takeda Pharmaceutical Company Limited |
Antibody drug conjugates
|
|
AU2022302611A1
(en)
|
2021-06-30 |
2024-02-15 |
Kyowa Kirin Co., Ltd. |
Polynucleotide and medicinal composition
|
|
JPWO2023167238A1
(enExample)
|
2022-03-02 |
2023-09-07 |
|
|
|
KR20250054799A
(ko)
|
2022-08-29 |
2025-04-23 |
다이이찌 산쿄 가부시키가이샤 |
변이 Fc 영역을 포함하는 항체 약물 콘쥬게이트
|
|
WO2026027944A1
(en)
|
2024-07-30 |
2026-02-05 |
Sairopa B.V. |
Anti-sirp alpha antibody formulations and uses thereof
|