|
JP6692826B2
(ja)
|
2015-03-10 |
2020-05-13 |
アドゥロ バイオテック，インク． |
「インターフェロン遺伝子刺激因子」依存性シグナル伝達の活性化のための組成物及び方法
|
|
BR112018002757A8
(pt)
|
2015-08-13 |
2023-04-11 |
Merck Sharp & Dohme |
Composto, composição farmacêutica, e, métodos para induzir uma resposta imune, para induzir uma produção de interferon tipo i e para tratamento de um distúrbio
|
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
KR20250049441A
(ko)
*
|
2016-01-11 |
2025-04-11 |
인네이트 튜머 이뮤니티, 인코포레이티드 |
Sting 활성과 연관된 상태 예컨대 암의 치료를 위한 시클릭 디뉴클레오티드
|
|
NZ746112A
(en)
|
2016-03-18 |
2023-01-27 |
Immune Sensor Llc |
Cyclic di-nucleotide compounds and methods of use
|
|
US11098077B2
(en)
|
2016-07-05 |
2021-08-24 |
Chinook Therapeutics, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
|
AU2017293781B2
(en)
|
2016-07-06 |
2022-12-22 |
Invox Pharma Limited |
Compounds, compositions, and methods for the treatment of disease
|
|
KR102497742B1
(ko)
|
2016-08-30 |
2023-02-10 |
다나-파버 캔서 인스티튜트 인크. |
약물 전달 조성물 및 그의 용도
|
|
EP3523287B1
(en)
|
2016-10-04 |
2021-09-01 |
Merck Sharp & Dohme Corp. |
Benzo[b]thiophene compounds as sting agonists
|
|
JOP20170192A1
(ar)
|
2016-12-01 |
2019-01-30 |
Takeda Pharmaceuticals Co |
داي نوكليوتيد حلقي
|
|
US20200055883A1
(en)
|
2017-02-17 |
2020-02-20 |
Eisai R&D Management Co., Ltd. |
Cyclic di-nucleotides derivative for the treatment of cancer
|
|
IL315837A
(en)
|
2017-04-13 |
2024-11-01 |
Sairopa B V |
Anti-SIRP-alpha antibodies
|
|
EP3621624B1
(en)
|
2017-05-12 |
2023-08-30 |
Merck Sharp & Dohme LLC |
Cyclic di-nucleotide compounds as sting agonists
|
|
US11259980B2
(en)
|
2017-07-31 |
2022-03-01 |
Arizona Board Of Regents On Behalf Of Arizona State University |
Soft inflatable exosuit for knee rehabilitation
|
|
RU2020109328A
(ru)
|
2017-08-04 |
2021-09-06 |
Мерк Шарп И Доум Корп. |
Комбинации антагонистов pd-1 и бензо[b]тиофеновых агонистов sting для лечения рака
|
|
EP3661498A4
(en)
|
2017-08-04 |
2021-04-21 |
Merck Sharp & Dohme Corp. |
BENZO [B] THIOPHEN STING ANTAGONISTS FOR CANCER TREATMENT
|
|
CA3073919A1
(en)
|
2017-08-30 |
2019-03-07 |
Beijing Xuanyi Pharmasciences Co., Ltd. |
Cyclic di-nucleotides as stimulator of interferon genes modulators
|
|
EP3676277A1
(en)
*
|
2017-08-31 |
2020-07-08 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
|
WO2019046511A1
(en)
|
2017-08-31 |
2019-03-07 |
Sperovie Biosciences, Inc. |
COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASE
|
|
WO2019051488A1
(en)
|
2017-09-11 |
2019-03-14 |
Sperovie Biosciences, Inc. |
COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISEASE
|
|
WO2019051489A1
(en)
|
2017-09-11 |
2019-03-14 |
Sperovie Biosciences, Inc. |
COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISEASE
|
|
WO2019053659A1
(en)
*
|
2017-09-14 |
2019-03-21 |
Alios Biopharma, Inc. |
PHOSPHORAMIDITES OF MODIFIED NUCLEOSIDES
|
|
EP3694867A1
(en)
*
|
2017-10-10 |
2020-08-19 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
|
WO2019084060A1
(en)
|
2017-10-24 |
2019-05-02 |
Silverback Therapeutics, Inc. |
CONJUGATES AND METHODS OF USE FOR THE SELECTIVE DELIVERY OF IMMUNOMODULATORY AGENTS
|
|
MX2020004858A
(es)
|
2017-11-10 |
2020-10-01 |
Takeda Pharmaceuticals Co |
Compuestos moduladores de sting y metodos de elaboracion y uso.
|
|
US11685761B2
(en)
|
2017-12-20 |
2023-06-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
AU2018392213B2
(en)
|
2017-12-20 |
2021-03-04 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3' cyclic dinucleotides with phosphonate bond activating the STING adaptor protein
|
|
WO2019123339A1
(en)
|
2017-12-20 |
2019-06-27 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
|
EP3505527A1
(en)
*
|
2017-12-29 |
2019-07-03 |
Invivogen |
Cyclic dinucleotides for cytokine induction
|
|
US10519187B2
(en)
|
2018-02-13 |
2019-12-31 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
|
KR20200130362A
(ko)
*
|
2018-03-08 |
2020-11-18 |
브리스톨-마이어스 스큅 컴퍼니 |
항암제로서의 시클릭 디뉴클레오티드
|
|
EP4242212A3
(en)
|
2018-03-23 |
2023-11-15 |
Takeda Pharmaceutical Company Limited |
Sting modulator compounds with sulfamate linkages, and methods of making and using
|
|
EP3774764A1
(en)
|
2018-04-03 |
2021-02-17 |
Merck Sharp&Dohme Corp. |
Benzothiophenes and related compounds as sting agonists
|
|
US11702430B2
(en)
|
2018-04-03 |
2023-07-18 |
Merck Sharp & Dohme Llc |
Aza-benzothiophene compounds as STING agonists
|
|
TWI833744B
(zh)
|
2018-04-06 |
2024-03-01 |
捷克科學院有機化學與生物化學研究所 |
3'3'-環二核苷酸
|
|
TWI818007B
(zh)
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
|
WO2019227007A1
(en)
|
2018-05-25 |
2019-11-28 |
Incyte Corporation |
Tricyclic heterocyclic compounds as sting activators
|
|
WO2020014127A1
(en)
|
2018-07-10 |
2020-01-16 |
Sperovie Biosciences, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
|
TW202030199A
(zh)
*
|
2018-07-17 |
2020-08-16 |
美商健生生物科技公司 |
作為ｓｔｉｎｇ促效劑之環狀二核苷酸
|
|
WO2020028565A1
(en)
|
2018-07-31 |
2020-02-06 |
Incyte Corporation |
Tricyclic heteraryl compounds as sting activators
|
|
WO2020028566A1
(en)
|
2018-07-31 |
2020-02-06 |
Incyte Corporation |
Heteroaryl amide compounds as sting activators
|
|
BR112021001349A2
(pt)
|
2018-08-16 |
2021-04-20 |
Eisai R&D Management Co., Ltd. |
sais de compostos e cristais dos mesmos
|
|
LT3848054T
(lt)
|
2018-09-06 |
2025-03-25 |
Daiichi Sankyo Company, Limited |
Ciklinių dinukleotidų darinių antikūno ir vaisto konjugatai
|
|
JP2022500414A
(ja)
|
2018-09-12 |
2022-01-04 |
シルバーバック セラピューティックス インコーポレイテッド |
免疫刺激性コンジュゲートにより疾患を処置する方法および組成物
|
|
MX2021003207A
(es)
|
2018-09-21 |
2021-06-23 |
Shanghai De Novo Pharmatech Co Ltd |
Analogo de dinucleotido ciclico. composicion farmaceutica del mismo y su aplicacion.
|
|
US11110106B2
(en)
|
2018-10-29 |
2021-09-07 |
Venenum Biodesign, LLC |
Sting agonists for treating bladder cancer and solid tumors
|
|
US11161864B2
(en)
|
2018-10-29 |
2021-11-02 |
Venenum Biodesign, LLC |
Sting agonists
|
|
WO2020089815A1
(en)
|
2018-10-31 |
2020-05-07 |
Novartis Ag |
Antibody conjugates comprising sting agonist
|
|
US11596692B1
(en)
|
2018-11-21 |
2023-03-07 |
Incyte Corporation |
PD-L1/STING conjugates and methods of use
|
|
CN113166184B
(zh)
*
|
2018-12-04 |
2024-06-18 |
百时美施贵宝公司 |
用于制备环状二核苷酸的方法
|
|
US12129267B2
(en)
|
2019-01-07 |
2024-10-29 |
Incyte Corporation |
Heteroaryl amide compounds as sting activators
|
|
US12060384B2
(en)
|
2019-02-05 |
2024-08-13 |
Bristol-Myers Squibb Company |
Synthesis of 1,2,5-tri-o-benzoyl-3-dibenzylamino-3-deoxyribose as intermediate for producing 3′-amino-3′-deoxyadenosine and 3′-amino-3′-deoxyguanosine and the protected derivatives thereof
|
|
IL287938B2
(en)
|
2019-05-10 |
2025-07-01 |
Takeda Pharmaceuticals Co |
Antibody-drug conjugates
|
|
EP3993834A1
(en)
|
2019-07-05 |
2022-05-11 |
Tambo, Inc. |
Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy
|
|
WO2021013234A1
(en)
*
|
2019-07-25 |
2021-01-28 |
Beigene, Ltd. |
Cyclic dinucleotides as sting agonists
|
|
WO2021067644A1
(en)
|
2019-10-01 |
2021-04-08 |
Silverback Therapeutics, Inc. |
Combination therapy with immune stimulatory conjugates
|
|
WO2021132589A1
(ja)
|
2019-12-26 |
2021-07-01 |
国立大学法人東海国立大学機構 |
ポリヌクレオチド及び医薬組成物
|
|
US11179473B2
(en)
|
2020-02-21 |
2021-11-23 |
Silverback Therapeutics, Inc. |
Nectin-4 antibody conjugates and uses thereof
|
|
IL296124A
(en)
|
2020-03-06 |
2022-11-01 |
Daiichi Sankyo Co Ltd |
Antibody-drug conjugate including novel cyclic dinucleotide derivative
|
|
JPWO2021206158A1
(enExample)
|
2020-04-10 |
2021-10-14 |
|
|
|
WO2021216698A1
(en)
*
|
2020-04-21 |
2021-10-28 |
Duke University |
Compositions and methods for the treatment of pain
|
|
WO2021228832A1
(en)
|
2020-05-11 |
2021-11-18 |
Erytech Pharma |
Red cell extracellular vesicles (rcevs) containing cargoes and methods of use and production thereof
|
|
CN116209678A
(zh)
|
2020-07-01 |
2023-06-02 |
安尔士制药公司 |
抗asgr1抗体缀合物及其用途
|
|
US20230256109A1
(en)
|
2020-08-07 |
2023-08-17 |
Tambo, Inc. |
Trans-Cyclooctene Bioorthogonal Agents and Uses in Cancer and Immunotherapy
|
|
CN116113641A
(zh)
|
2020-09-02 |
2023-05-12 |
第一三共株式会社 |
新型内－β－N－乙酰氨基葡萄糖苷酶
|
|
US20240277751A1
(en)
*
|
2020-10-15 |
2024-08-22 |
The Regents Of The University Of Michigan |
Crystalline polymorphic forms of sting agonists associated with metal ions capable of modulating an immune response
|
|
KR102466750B1
(ko)
|
2020-10-23 |
2022-11-15 |
아주대학교산학협력단 |
인돌리진 유도체를 유효성분으로 포함하는 인터페론 유전자 자극제 조성물
|
|
KR20230141754A
(ko)
|
2020-10-30 |
2023-10-10 |
아박타 라이프 사이언시스 리미티드 |
Fap-활성화 혈청 반감기 연장된 치료 접합체
|
|
TW202233251A
(zh)
|
2020-11-09 |
2022-09-01 |
日商武田藥品工業股份有限公司 |
抗體藥物綴合物
|
|
CA3225964A1
(en)
|
2021-06-30 |
2023-01-25 |
Kyowa Kirin Co., Ltd. |
Polynucleotide and pharmaceutical composition
|
|
WO2023167238A1
(ja)
|
2022-03-02 |
2023-09-07 |
第一三共株式会社 |
Ｆｃ含有分子の製造方法
|
|
EP4582106A1
(en)
|
2022-08-29 |
2025-07-09 |
Daiichi Sankyo Company, Limited |
Antibody-drug conjugate including mutant fc region
|