JP2016520082A5 - - Google Patents
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- Publication number
- JP2016520082A5 JP2016520082A5 JP2016514047A JP2016514047A JP2016520082A5 JP 2016520082 A5 JP2016520082 A5 JP 2016520082A5 JP 2016514047 A JP2016514047 A JP 2016514047A JP 2016514047 A JP2016514047 A JP 2016514047A JP 2016520082 A5 JP2016520082 A5 JP 2016520082A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- seq
- medicament
- medicament according
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361823317P | 2013-05-14 | 2013-05-14 | |
| US61/823,317 | 2013-05-14 | ||
| US201361828586P | 2013-05-29 | 2013-05-29 | |
| US61/828,586 | 2013-05-29 | ||
| PCT/US2014/037911 WO2014186403A2 (en) | 2013-05-14 | 2014-05-13 | Anti-folr1 immunoconjugate dosing regimens |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018143909A Division JP2018197249A (ja) | 2013-05-14 | 2018-07-31 | 抗ｆｏｌｒ１免疫複合体投与計画 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016520082A JP2016520082A (ja) | 2016-07-11 |
| JP2016520082A5 true JP2016520082A5 (enExample) | 2017-06-29 |
Family
ID=51898993
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016514047A Withdrawn JP2016520082A (ja) | 2013-05-14 | 2014-05-13 | 抗ｆｏｌｒ１免疫複合体投与計画 |
| JP2018143909A Withdrawn JP2018197249A (ja) | 2013-05-14 | 2018-07-31 | 抗ｆｏｌｒ１免疫複合体投与計画 |
| JP2021062774A Withdrawn JP2021102648A (ja) | 2013-05-14 | 2021-04-01 | 抗ｆｏｌｒ１免疫複合体投与計画 |
| JP2023145920A Pending JP2023162436A (ja) | 2013-05-14 | 2023-09-08 | 抗ｆｏｌｒ１免疫複合体投与計画 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018143909A Withdrawn JP2018197249A (ja) | 2013-05-14 | 2018-07-31 | 抗ｆｏｌｒ１免疫複合体投与計画 |
| JP2021062774A Withdrawn JP2021102648A (ja) | 2013-05-14 | 2021-04-01 | 抗ｆｏｌｒ１免疫複合体投与計画 |
| JP2023145920A Pending JP2023162436A (ja) | 2013-05-14 | 2023-09-08 | 抗ｆｏｌｒ１免疫複合体投与計画 |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US20140363451A1 (enExample) |
| EP (1) | EP2997044A4 (enExample) |
| JP (4) | JP2016520082A (enExample) |
| KR (4) | KR20230066648A (enExample) |
| CN (2) | CN105308072A (enExample) |
| AU (3) | AU2014265587A1 (enExample) |
| BR (1) | BR112015028244A2 (enExample) |
| CA (1) | CA2911499A1 (enExample) |
| HK (1) | HK1222340A1 (enExample) |
| IL (1) | IL268180A (enExample) |
| MX (2) | MX2015015735A (enExample) |
| RU (1) | RU2015149285A (enExample) |
| SG (2) | SG10201701096UA (enExample) |
| WO (1) | WO2014186403A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105777907B (zh) | 2010-02-24 | 2020-03-17 | 伊缪诺金公司 | 叶酸受体1抗体与免疫缀合物以及其用途 |
| ES2661466T3 (es) | 2011-04-01 | 2018-04-02 | Immunogen, Inc. | Métodos para aumentar la eficacia de la terapia contra el cáncer con FOLR1 |
| SG11201500938XA (en) | 2012-08-31 | 2015-04-29 | Immunogen Inc | Diagnostic assays and kits for detection of folate receptor 1 |
| NZ717140A (en) | 2013-08-30 | 2022-05-27 | Immunogen Inc | Antibodies and assays for detection of folate receptor 1 |
| JP6463744B2 (ja) * | 2013-10-08 | 2019-02-06 | イミュノジェン， インコーポレイテッド | 抗ｆｏｌｒ１免疫抱合体投薬レジメン |
| CN122075735A (zh) | 2015-09-17 | 2026-05-26 | 伊缪诺金公司 | 包含抗folr1免疫缀合物的治疗组合 |
| KR102584446B1 (ko) | 2016-08-12 | 2023-10-04 | 엘.이.에이.에프. 홀딩스 그룹 엘엘씨. | 알파 및 감마-d 폴리글루타메이트화 항엽산 및 이의 용도 |
| US20180236098A1 (en) | 2016-08-12 | 2018-08-23 | L.E.A.F. Holdings Group Llc | Alpha and gamma-d polyglutamated antifolates and uses thereof |
| MA50265A (fr) * | 2017-09-18 | 2020-07-29 | Sutro Biopharma Inc | Conjugués anticorps-récepteur alpha anti-folate et leurs utilisations |
| WO2019157133A1 (en) | 2018-02-07 | 2019-08-15 | L.E.A.F. Holdings Group Llc | Alpha polyglutamated raltitrexed and uses thereof |
| CA3090384A1 (en) | 2018-02-07 | 2019-08-15 | L.E.A.F. Holdings Group Llc | Alpha polyglutamated aminopterin and uses thereof |
| JP7491573B2 (ja) | 2018-02-07 | 2024-05-28 | エル．イー．エー．エフ． ホールディングス グループ エルエルシー | アルファポリグルタミン酸化メトトレキセートおよびその使用 |
| WO2019157146A1 (en) | 2018-02-07 | 2019-08-15 | L.E.A.F. Holdings Group Llc | Alpha polyglutamated antifolates and uses thereof |
| EP3749317A4 (en) | 2018-02-07 | 2022-06-22 | L.E.A.F Holdings Group LLC | PEMETREXED ALPHA-POLYGLUTAMATE AND ASSOCIATED USES |
| US12220431B2 (en) | 2018-02-07 | 2025-02-11 | L.E.A.F. Holdings Group Llc | Gamma polyglutamated antifolates and uses thereof |
| US12246018B2 (en) | 2018-02-07 | 2025-03-11 | L.E.A.F. Holdings Group Llc | Gamma polyglutamated pemetrexed and uses thereof |
| CA3090391A1 (en) | 2018-02-07 | 2019-08-15 | L.E.A.F. Holdings Group Llc | Gamma polyglutamated raltitrexed and uses thereof |
| US12246019B2 (en) | 2018-02-07 | 2025-03-11 | L.E.A.F. Holdings Group Llc | Alpha polyglutamated lometrexol and uses thereof |
| WO2019157129A1 (en) | 2018-02-07 | 2019-08-15 | L.E.A.F. Holdings Group Llc | Alpha polyglutamated pralatrexate and uses thereof |
| JP7514533B2 (ja) | 2018-02-07 | 2024-07-11 | エル．イー．エー．エフ． ホールディングス グループ エルエルシー | アルファポリグルタミン酸化テトラヒドロ葉酸およびその使用 |
| JP7442822B2 (ja) | 2018-02-14 | 2024-03-05 | エル．イー．エー．エフ． ホールディングス グループ エルエルシー | γポリグルタミン酸化テトラヒドロ葉酸およびその使用 |
| US12048767B2 (en) | 2018-02-14 | 2024-07-30 | L.E.A.F. Holdings Group Llc | Gamma polyglutamated pralatrexate and uses thereof |
| US12290518B2 (en) | 2018-02-14 | 2025-05-06 | L.E.A.F. Holdings Group Llc | Gamma polyglutamated methotrexate and uses thereof |
| CA3090943A1 (en) | 2018-02-14 | 2019-08-22 | L.E.A.F. Holdings Group Llc | Gamma polyglutamated aminopterin and uses thereof |
| CA3090875A1 (en) | 2018-02-14 | 2019-08-22 | L.E.A.F. Holdings Group Llc | Gamma polyglutamated lometrexol and uses thereof |
| EP3765521A4 (en) | 2018-03-13 | 2022-03-23 | Phanes Therapeutics, Inc. | ANTI-FOLATE RECEPTOR-1 ANTIBODIES AND USES THEREOF |
| WO2020092533A2 (en) * | 2018-10-30 | 2020-05-07 | Immunogen, Inc. | Methods of treatment using anti-cd123 immunoconjugates |
| SG11202111109UA (en) | 2019-04-29 | 2021-11-29 | Immunogen Inc | Biparatopic fr-alpha antibodies and immunoconjugates |
| CN112794911B (zh) * | 2021-04-14 | 2021-08-03 | 上海偌妥生物科技有限公司 | 人源化抗叶酸受体1抗体及其应用 |
| CN116333135A (zh) * | 2021-12-24 | 2023-06-27 | 百奥泰生物制药股份有限公司 | 抗FRα抗体及其抗体药物偶联物和用途 |
| CN121772942A (zh) * | 2023-08-11 | 2026-03-31 | 百奥泰生物制药股份有限公司 | 抗FRα抗体药物偶联物在治疗疾病中的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020151508A1 (en) * | 2001-02-09 | 2002-10-17 | Schering Corporation | Methods for treating proliferative diseases |
| US20080131366A1 (en) * | 2003-03-17 | 2008-06-05 | Manohar Ratnam | Folate Receptor Gene Modulation For Cancer Diagnosis And Therapy |
| CA2556027C (en) * | 2004-02-12 | 2015-11-24 | Morphotek, Inc. | Monoclonal antibodies that specifically block biological activity of a tumor antigen |
| MX2012004406A (es) * | 2009-10-21 | 2012-05-08 | Immunogen Inc | Nuevo regimen de dosificacion y metodo de tratamiento. |
| CN105777907B (zh) * | 2010-02-24 | 2020-03-17 | 伊缪诺金公司 | 叶酸受体1抗体与免疫缀合物以及其用途 |
| ES2661466T3 (es) * | 2011-04-01 | 2018-04-02 | Immunogen, Inc. | Métodos para aumentar la eficacia de la terapia contra el cáncer con FOLR1 |
| US20120282282A1 (en) * | 2011-04-04 | 2012-11-08 | Immunogen, Inc. | Methods for Decreasing Ocular Toxicity of Antibody Drug Conjugates |
| JP6463744B2 (ja) * | 2013-10-08 | 2019-02-06 | イミュノジェン， インコーポレイテッド | 抗ｆｏｌｒ１免疫抱合体投薬レジメン |
| CN122075735A (zh) * | 2015-09-17 | 2026-05-26 | 伊缪诺金公司 | 包含抗folr1免疫缀合物的治疗组合 |
| SG11202111109UA (en) * | 2019-04-29 | 2021-11-29 | Immunogen Inc | Biparatopic fr-alpha antibodies and immunoconjugates |
-
2014
- 2014-05-13 EP EP14798020.5A patent/EP2997044A4/en not_active Withdrawn
- 2014-05-13 WO PCT/US2014/037911 patent/WO2014186403A2/en not_active Ceased
- 2014-05-13 RU RU2015149285A patent/RU2015149285A/ru not_active Application Discontinuation
- 2014-05-13 KR KR1020237014635A patent/KR20230066648A/ko not_active Ceased
- 2014-05-13 BR BR112015028244A patent/BR112015028244A2/pt not_active Application Discontinuation
- 2014-05-13 CN CN201480027385.9A patent/CN105308072A/zh active Pending
- 2014-05-13 JP JP2016514047A patent/JP2016520082A/ja not_active Withdrawn
- 2014-05-13 SG SG10201701096UA patent/SG10201701096UA/en unknown
- 2014-05-13 HK HK16110621.8A patent/HK1222340A1/zh unknown
- 2014-05-13 KR KR1020247014907A patent/KR20240068778A/ko not_active Ceased
- 2014-05-13 CN CN202410768087.0A patent/CN119185571A/zh active Pending
- 2014-05-13 MX MX2015015735A patent/MX2015015735A/es unknown
- 2014-05-13 SG SG11201509043RA patent/SG11201509043RA/en unknown
- 2014-05-13 AU AU2014265587A patent/AU2014265587A1/en not_active Abandoned
- 2014-05-13 KR KR1020227012937A patent/KR20220054700A/ko not_active Ceased
- 2014-05-13 CA CA2911499A patent/CA2911499A1/en active Pending
- 2014-05-13 US US14/276,917 patent/US20140363451A1/en not_active Abandoned
- 2014-05-13 KR KR1020157034078A patent/KR20160020421A/ko not_active Ceased
-
2015
- 2015-11-13 MX MX2019008028A patent/MX2019008028A/es unknown
-
2016
- 2016-12-22 US US15/388,873 patent/US20170239367A1/en not_active Abandoned
-
2018
- 2018-07-31 JP JP2018143909A patent/JP2018197249A/ja not_active Withdrawn
-
2019
- 2019-04-19 US US16/389,396 patent/US20200046634A1/en not_active Abandoned
- 2019-07-21 IL IL268180A patent/IL268180A/en unknown
- 2019-10-15 AU AU2019250121A patent/AU2019250121A1/en not_active Abandoned
-
2021
- 2021-04-01 JP JP2021062774A patent/JP2021102648A/ja not_active Withdrawn
- 2021-10-11 AU AU2021250837A patent/AU2021250837A1/en not_active Abandoned
-
2022
- 2022-04-14 US US17/720,766 patent/US20220378694A1/en not_active Abandoned
-
2023
- 2023-09-08 JP JP2023145920A patent/JP2023162436A/ja active Pending
-
2025
- 2025-03-17 US US19/081,150 patent/US20250262217A1/en active Pending