JP2016534039A5 - - Google Patents
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- Publication number
- JP2016534039A5 JP2016534039A5 JP2016521270A JP2016521270A JP2016534039A5 JP 2016534039 A5 JP2016534039 A5 JP 2016534039A5 JP 2016521270 A JP2016521270 A JP 2016521270A JP 2016521270 A JP2016521270 A JP 2016521270A JP 2016534039 A5 JP2016534039 A5 JP 2016534039A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- item
- cancer
- immunoconjugate
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361888365P | 2013-10-08 | 2013-10-08 | |
| US201361888337P | 2013-10-08 | 2013-10-08 | |
| US61/888,365 | 2013-10-08 | ||
| US61/888,337 | 2013-10-08 | ||
| US201461948363P | 2014-03-05 | 2014-03-05 | |
| US61/948,363 | 2014-03-05 | ||
| US201462004815P | 2014-05-29 | 2014-05-29 | |
| US62/004,815 | 2014-05-29 | ||
| PCT/US2014/059716 WO2015054400A2 (en) | 2013-10-08 | 2014-10-08 | Anti-folr1 immunoconjugate dosing regimens |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018208158A Division JP6581279B2 (ja) | 2013-10-08 | 2018-11-05 | 抗folr1免疫抱合体投薬レジメン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016534039A JP2016534039A (ja) | 2016-11-04 |
| JP2016534039A5 true JP2016534039A5 (enExample) | 2017-11-16 |
| JP6463744B2 JP6463744B2 (ja) | 2019-02-06 |
Family
ID=52813740
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016521270A Active JP6463744B2 (ja) | 2013-10-08 | 2014-10-08 | 抗folr1免疫抱合体投薬レジメン |
| JP2018208158A Active JP6581279B2 (ja) | 2013-10-08 | 2018-11-05 | 抗folr1免疫抱合体投薬レジメン |
| JP2019156399A Withdrawn JP2019218386A (ja) | 2013-10-08 | 2019-08-29 | 抗folr1免疫抱合体投薬レジメン |
| JP2021125147A Active JP7386208B2 (ja) | 2013-10-08 | 2021-07-30 | 抗folr1免疫抱合体投薬レジメン |
| JP2023192883A Pending JP2024016239A (ja) | 2013-10-08 | 2023-11-13 | 抗folr1免疫抱合体投薬レジメン |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018208158A Active JP6581279B2 (ja) | 2013-10-08 | 2018-11-05 | 抗folr1免疫抱合体投薬レジメン |
| JP2019156399A Withdrawn JP2019218386A (ja) | 2013-10-08 | 2019-08-29 | 抗folr1免疫抱合体投薬レジメン |
| JP2021125147A Active JP7386208B2 (ja) | 2013-10-08 | 2021-07-30 | 抗folr1免疫抱合体投薬レジメン |
| JP2023192883A Pending JP2024016239A (ja) | 2013-10-08 | 2023-11-13 | 抗folr1免疫抱合体投薬レジメン |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | US20150132323A1 (enExample) |
| EP (3) | EP3055332B1 (enExample) |
| JP (5) | JP6463744B2 (enExample) |
| KR (7) | KR102303874B1 (enExample) |
| CN (1) | CN106164093A (enExample) |
| AU (4) | AU2014331964C1 (enExample) |
| BR (1) | BR112016007479A2 (enExample) |
| CA (1) | CA2926325C (enExample) |
| CY (1) | CY1122449T1 (enExample) |
| DK (2) | DK3653228T3 (enExample) |
| ES (2) | ES2759426T3 (enExample) |
| FI (1) | FI3653228T3 (enExample) |
| HR (2) | HRP20192140T1 (enExample) |
| HU (2) | HUE046696T2 (enExample) |
| IL (4) | IL298044B2 (enExample) |
| LT (2) | LT3653228T (enExample) |
| MX (2) | MX384973B (enExample) |
| MY (1) | MY174670A (enExample) |
| NZ (2) | NZ718766A (enExample) |
| PL (2) | PL3653228T3 (enExample) |
| PT (2) | PT3055332T (enExample) |
| RS (2) | RS59644B1 (enExample) |
| RU (1) | RU2696579C2 (enExample) |
| SG (3) | SG10201907042PA (enExample) |
| SI (2) | SI3055332T1 (enExample) |
| SM (1) | SMT201900694T1 (enExample) |
| UA (1) | UA119541C2 (enExample) |
| WO (1) | WO2015054400A2 (enExample) |
| ZA (1) | ZA201902009B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI672318B (zh) | 2010-02-24 | 2019-09-21 | 美商免疫遺傳股份有限公司 | 葉酸受體1抗體類和免疫共軛物類及彼等之用途 |
| CN114441757A (zh) | 2011-04-01 | 2022-05-06 | 伊缪诺金公司 | 用于增加folr1癌症治疗的功效的方法 |
| PL2890717T3 (pl) | 2012-08-31 | 2020-08-10 | Immunogen, Inc. | Testy i zestawy diagnostyczne do wykrywania receptora folianu |
| US20140363451A1 (en) * | 2013-05-14 | 2014-12-11 | Immunogen, Inc. | Anti-FOLR1 Immunoconjugate Dosing Regimens |
| CN105814079B (zh) | 2013-08-30 | 2021-02-09 | 伊缪诺金公司 | 用于检测叶酸受体1的抗体和测定 |
| KR102700777B1 (ko) * | 2015-09-17 | 2024-08-29 | 이뮤노젠 아이엔씨 | 항-folr1 면역접합체를 포함하는 치료제 조합 |
| RU2019141270A (ru) * | 2017-05-16 | 2021-06-16 | Иммуноджен, Инк. | Комбинации анти-folr1 иммуноконъюгатов и анти-pd-1 антител |
| KR20200051802A (ko) | 2017-09-18 | 2020-05-13 | 서트로 바이오파마, 인크. | 항-엽산 수용체 알파 항체 접합체 및 이의 용도 |
| CN115925952A (zh) | 2018-03-13 | 2023-04-07 | 东莞凡恩世生物医药有限公司 | 抗叶酸受体1抗体及其用途 |
| JP7623939B2 (ja) | 2018-07-09 | 2025-01-29 | マルチチュード インコーポレーテッド | 葉酸受容体アルファに特異的な抗体 |
| MA55818A (fr) | 2019-04-29 | 2022-03-16 | Immunogen Inc | Anticorps et immunoconjugués de fr-alpha biparatopique |
| JP2024522544A (ja) * | 2021-06-04 | 2024-06-21 | イミュノジェン, インコーポレイテッド | 可溶性FR-α患者におけるがんの治療 |
| US20240408228A1 (en) * | 2021-12-01 | 2024-12-12 | Sutro Biopharma, Inc. | Anti-folate receptor conjugate cancer therapy |
| WO2023116911A1 (zh) * | 2021-12-24 | 2023-06-29 | 百奥泰生物制药股份有限公司 | 抗FRα抗体及其抗体药物偶联物和用途 |
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| US4256746A (en) | 1978-11-14 | 1981-03-17 | Takeda Chemical Industries | Dechloromaytansinoids, their pharmaceutical compositions and method of use |
| JPS55102583A (en) | 1979-01-31 | 1980-08-05 | Takeda Chem Ind Ltd | 20-acyloxy-20-demethylmaytansinoid compound |
| JPS55162791A (en) | 1979-06-05 | 1980-12-18 | Takeda Chem Ind Ltd | Antibiotic c-15003pnd and its preparation |
| JPS5645483A (en) | 1979-09-19 | 1981-04-25 | Takeda Chem Ind Ltd | C-15003phm and its preparation |
| EP0028683A1 (en) | 1979-09-21 | 1981-05-20 | Takeda Chemical Industries, Ltd. | Antibiotic C-15003 PHO and production thereof |
| JPS5645485A (en) | 1979-09-21 | 1981-04-25 | Takeda Chem Ind Ltd | Production of c-15003pnd |
| WO1982001188A1 (en) | 1980-10-08 | 1982-04-15 | Takeda Chemical Industries Ltd | 4,5-deoxymaytansinoide compounds and process for preparing same |
| US4450254A (en) | 1980-11-03 | 1984-05-22 | Standard Oil Company | Impact improvement of high nitrile resins |
| US4313946A (en) | 1981-01-27 | 1982-02-02 | The United States Of America As Represented By The Secretary Of Agriculture | Chemotherapeutically active maytansinoids from Trewia nudiflora |
| US4315929A (en) | 1981-01-27 | 1982-02-16 | The United States Of America As Represented By The Secretary Of Agriculture | Method of controlling the European corn borer with trewiasine |
| US4563304A (en) | 1981-02-27 | 1986-01-07 | Pharmacia Fine Chemicals Ab | Pyridine compounds modifying proteins, polypeptides or polysaccharides |
| JPS57192389A (en) | 1981-05-20 | 1982-11-26 | Takeda Chem Ind Ltd | Novel maytansinoid |
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| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| US6172197B1 (en) | 1991-07-10 | 2001-01-09 | Medical Research Council | Methods for producing members of specific binding pairs |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
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| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| ES2108048T3 (es) | 1990-08-29 | 1997-12-16 | Genpharm Int | Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos. |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| DE69129154T2 (de) | 1990-12-03 | 1998-08-20 | Genentech, Inc., South San Francisco, Calif. | Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften |
| ATE463573T1 (de) | 1991-12-02 | 2010-04-15 | Medimmune Ltd | Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken |
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| US6828422B1 (en) | 1995-08-18 | 2004-12-07 | Morphosys Ag | Protein/(poly)peptide libraries |
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| WO2001002588A2 (en) | 1999-07-02 | 2001-01-11 | Morphosys Ag | Generation of specific binding partners binding to (poly)peptides encoded by genomic dna fragments or ests |
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| GB0202319D0 (en) | 2002-02-01 | 2002-03-20 | Calex Electronics Ltd | Apparatus |
| WO2004082463A2 (en) * | 2003-03-17 | 2004-09-30 | Medical College Of Ohio | Folate receptor gene modulation for cancer diagnosis and therapy |
| US8088387B2 (en) | 2003-10-10 | 2012-01-03 | Immunogen Inc. | Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates |
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| TWI672318B (zh) | 2010-02-24 | 2019-09-21 | 美商免疫遺傳股份有限公司 | 葉酸受體1抗體類和免疫共軛物類及彼等之用途 |
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| PL2890717T3 (pl) * | 2012-08-31 | 2020-08-10 | Immunogen, Inc. | Testy i zestawy diagnostyczne do wykrywania receptora folianu |
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| US20140363451A1 (en) * | 2013-05-14 | 2014-12-11 | Immunogen, Inc. | Anti-FOLR1 Immunoconjugate Dosing Regimens |
| CN105814079B (zh) * | 2013-08-30 | 2021-02-09 | 伊缪诺金公司 | 用于检测叶酸受体1的抗体和测定 |
| KR102700777B1 (ko) * | 2015-09-17 | 2024-08-29 | 이뮤노젠 아이엔씨 | 항-folr1 면역접합체를 포함하는 치료제 조합 |
-
2014
- 2014-10-08 MY MYPI2016000551A patent/MY174670A/en unknown
- 2014-10-08 BR BR112016007479A patent/BR112016007479A2/pt not_active Application Discontinuation
- 2014-10-08 FI FIEP19199163.7T patent/FI3653228T3/fi active
- 2014-10-08 MX MX2016004411A patent/MX384973B/es unknown
- 2014-10-08 CA CA2926325A patent/CA2926325C/en active Active
- 2014-10-08 PT PT148528342T patent/PT3055332T/pt unknown
- 2014-10-08 WO PCT/US2014/059716 patent/WO2015054400A2/en not_active Ceased
- 2014-10-08 NZ NZ718766A patent/NZ718766A/en unknown
- 2014-10-08 HU HUE14852834A patent/HUE046696T2/hu unknown
- 2014-10-08 KR KR1020217010200A patent/KR102303874B1/ko active Active
- 2014-10-08 SG SG10201907042PA patent/SG10201907042PA/en unknown
- 2014-10-08 RS RS20191523A patent/RS59644B1/sr unknown
- 2014-10-08 KR KR1020227033036A patent/KR20220136468A/ko not_active Ceased
- 2014-10-08 SI SI201431419T patent/SI3055332T1/sl unknown
- 2014-10-08 JP JP2016521270A patent/JP6463744B2/ja active Active
- 2014-10-08 EP EP14852834.2A patent/EP3055332B1/en active Active
- 2014-10-08 HR HRP20192140TT patent/HRP20192140T1/hr unknown
- 2014-10-08 LT LTEP19199163.7T patent/LT3653228T/lt unknown
- 2014-10-08 KR KR1020167012025A patent/KR102115217B1/ko active Active
- 2014-10-08 LT LTEP14852834.2T patent/LT3055332T/lt unknown
- 2014-10-08 DK DK19199163.7T patent/DK3653228T3/da active
- 2014-10-08 HR HRP20240917TT patent/HRP20240917T1/hr unknown
- 2014-10-08 NZ NZ757964A patent/NZ757964A/en unknown
- 2014-10-08 SG SG11201602361UA patent/SG11201602361UA/en unknown
- 2014-10-08 RS RS20240830A patent/RS65798B1/sr unknown
- 2014-10-08 EP EP19199163.7A patent/EP3653228B1/en active Active
- 2014-10-08 EP EP24170072.3A patent/EP4424323A3/en not_active Withdrawn
- 2014-10-08 DK DK14852834T patent/DK3055332T3/da active
- 2014-10-08 PL PL19199163.7T patent/PL3653228T3/pl unknown
- 2014-10-08 KR KR1020237034405A patent/KR102639861B1/ko active Active
- 2014-10-08 KR KR1020207014364A patent/KR20200058592A/ko not_active Ceased
- 2014-10-08 HU HUE19199163A patent/HUE067367T2/hu unknown
- 2014-10-08 KR KR1020247005572A patent/KR20240027861A/ko active Pending
- 2014-10-08 RU RU2016114708A patent/RU2696579C2/ru active
- 2014-10-08 AU AU2014331964A patent/AU2014331964C1/en active Active
- 2014-10-08 KR KR1020217029508A patent/KR20210118220A/ko not_active Ceased
- 2014-10-08 IL IL298044A patent/IL298044B2/en unknown
- 2014-10-08 IL IL313730A patent/IL313730A/en unknown
- 2014-10-08 UA UAA201604168A patent/UA119541C2/uk unknown
- 2014-10-08 PT PT191991637T patent/PT3653228T/pt unknown
- 2014-10-08 SM SM20190694T patent/SMT201900694T1/it unknown
- 2014-10-08 SI SI201432085T patent/SI3653228T1/sl unknown
- 2014-10-08 US US14/509,809 patent/US20150132323A1/en active Pending
- 2014-10-08 PL PL14852834T patent/PL3055332T3/pl unknown
- 2014-10-08 ES ES14852834T patent/ES2759426T3/es active Active
- 2014-10-08 CN CN201480055444.3A patent/CN106164093A/zh active Pending
- 2014-10-08 ES ES19199163T patent/ES2983055T3/es active Active
- 2014-10-08 SG SG10202102555TA patent/SG10202102555TA/en unknown
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2016
- 2016-03-27 IL IL244772A patent/IL244772B/en active IP Right Grant
- 2016-04-06 MX MX2021009222A patent/MX2021009222A/es unknown
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2018
- 2018-11-05 JP JP2018208158A patent/JP6581279B2/ja active Active
- 2018-12-11 AU AU2018278880A patent/AU2018278880A1/en not_active Abandoned
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2019
- 2019-03-24 IL IL265586A patent/IL265586A/en unknown
- 2019-03-28 ZA ZA2019/02009A patent/ZA201902009B/en unknown
- 2019-08-29 JP JP2019156399A patent/JP2019218386A/ja not_active Withdrawn
- 2019-12-02 CY CY20191101260T patent/CY1122449T1/el unknown
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2020
- 2020-11-03 AU AU2020264270A patent/AU2020264270B2/en active Active
-
2021
- 2021-01-15 US US17/150,379 patent/US20210155688A1/en not_active Abandoned
- 2021-07-30 JP JP2021125147A patent/JP7386208B2/ja active Active
-
2023
- 2023-11-13 JP JP2023192883A patent/JP2024016239A/ja active Pending
-
2024
- 2024-03-12 AU AU2024201615A patent/AU2024201615A1/en active Pending
- 2024-04-12 US US18/634,736 patent/US20240368270A1/en active Pending
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