|
US4307016A
(en)
|
1978-03-24 |
1981-12-22 |
Takeda Chemical Industries, Ltd. |
Demethyl maytansinoids
|
|
US4256746A
(en)
|
1978-11-14 |
1981-03-17 |
Takeda Chemical Industries |
Dechloromaytansinoids, their pharmaceutical compositions and method of use
|
|
JPS55102583A
(en)
|
1979-01-31 |
1980-08-05 |
Takeda Chem Ind Ltd |
20-acyloxy-20-demethylmaytansinoid compound
|
|
JPS55162791A
(en)
|
1979-06-05 |
1980-12-18 |
Takeda Chem Ind Ltd |
Antibiotic c-15003pnd and its preparation
|
|
JPS5645483A
(en)
|
1979-09-19 |
1981-04-25 |
Takeda Chem Ind Ltd |
C-15003phm and its preparation
|
|
JPS5645485A
(en)
|
1979-09-21 |
1981-04-25 |
Takeda Chem Ind Ltd |
Production of c-15003pnd
|
|
EP0028683A1
(en)
|
1979-09-21 |
1981-05-20 |
Takeda Chemical Industries, Ltd. |
Antibiotic C-15003 PHO and production thereof
|
|
WO1982001188A1
(en)
|
1980-10-08 |
1982-04-15 |
Takeda Chemical Industries Ltd |
4,5-deoxymaytansinoide compounds and process for preparing same
|
|
US4450254A
(en)
|
1980-11-03 |
1984-05-22 |
Standard Oil Company |
Impact improvement of high nitrile resins
|
|
US4315929A
(en)
|
1981-01-27 |
1982-02-16 |
The United States Of America As Represented By The Secretary Of Agriculture |
Method of controlling the European corn borer with trewiasine
|
|
US4313946A
(en)
|
1981-01-27 |
1982-02-02 |
The United States Of America As Represented By The Secretary Of Agriculture |
Chemotherapeutically active maytansinoids from Trewia nudiflora
|
|
US4563304A
(en)
|
1981-02-27 |
1986-01-07 |
Pharmacia Fine Chemicals Ab |
Pyridine compounds modifying proteins, polypeptides or polysaccharides
|
|
JPS57192389A
(en)
|
1981-05-20 |
1982-11-26 |
Takeda Chem Ind Ltd |
Novel maytansinoid
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
JP3040121B2
(ja)
|
1988-01-12 |
2000-05-08 |
ジェネンテク,インコーポレイテッド |
増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
US20030229208A1
(en)
|
1988-12-28 |
2003-12-11 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5108921A
(en)
|
1989-04-03 |
1992-04-28 |
Purdue Research Foundation |
Method for enhanced transmembrane transport of exogenous molecules
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US6172197B1
(en)
|
1991-07-10 |
2001-01-09 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
US6916605B1
(en)
|
1990-07-10 |
2005-07-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
JP2938569B2
(ja)
|
1990-08-29 |
1999-08-23 |
ジェンファーム インターナショナル,インコーポレイティド |
異種免疫グロブリンを作る方法及びトランスジェニックマウス
|
|
WO1992009690A2
(en)
|
1990-12-03 |
1992-06-11 |
Genentech, Inc. |
Enrichment method for variant proteins with altered binding properties
|
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
WO1993011236A1
(en)
|
1991-12-02 |
1993-06-10 |
Medical Research Council |
Production of anti-self antibodies from antibody segment repertoires and displayed on phage
|
|
AU3737893A
(en)
|
1992-03-05 |
1993-10-05 |
Board Of Regents, The University Of Texas System |
Diagnostic and/or therapeutic agents, targeted to neovascular endothelial cells
|
|
US5965132A
(en)
|
1992-03-05 |
1999-10-12 |
Board Of Regents, The University Of Texas System |
Methods and compositions for targeting the vasculature of solid tumors
|
|
US20030148406A1
(en)
|
1992-03-17 |
2003-08-07 |
David John King |
Multivalent antigen-binding proteins
|
|
DE69231123T2
(de)
|
1992-03-25 |
2001-02-15 |
Immunogen Inc |
Konjugaten von Zell-bindender Mittel und Derivaten von CC-1065
|
|
WO1994029351A2
(en)
|
1993-06-16 |
1994-12-22 |
Celltech Limited |
Antibodies
|
|
ES2176484T3
(es)
|
1995-08-18 |
2002-12-01 |
Morphosys Ag |
Bancos de proteinas/(poli)peptidos.
|
|
US7264963B1
(en)
|
1995-08-18 |
2007-09-04 |
Morphosys Ag |
Protein(poly)peptide libraries
|
|
JP2002514895A
(ja)
|
1995-09-28 |
2002-05-21 |
アレクション、ファーマスーティカルズ、インコーポレーテッド |
ブタ細胞相互作用タンパク質
|
|
US6596850B1
(en)
|
1998-01-30 |
2003-07-22 |
Ixsys, Incorporated |
Anti-αv3β3 recombinant human antibodies, nucleic acids encoding same
|
|
US6884879B1
(en)
|
1997-04-07 |
2005-04-26 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
US20020032315A1
(en)
|
1997-08-06 |
2002-03-14 |
Manuel Baca |
Anti-vegf antibodies
|
|
ES2273415T3
(es)
|
1997-04-07 |
2007-05-01 |
Genentech, Inc. |
Anticuerpos anti-vegf.
|
|
US20070059302A1
(en)
|
1997-04-07 |
2007-03-15 |
Genentech, Inc. |
Anti-vegf antibodies
|
|
CA2354862A1
(en)
|
1998-10-19 |
2000-04-27 |
Yeda Research And Development Co. Ltd. |
Treatment of systemic lupus erythematosus by down-regulating the autoimmune response to autoantigens
|
|
US20040031072A1
(en)
|
1999-05-06 |
2004-02-12 |
La Rosa Thomas J. |
Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
|
|
ATE482275T1
(de)
|
1999-07-02 |
2010-10-15 |
Morphosys Ag |
Erzeugung spezifischer bindungspartner die an von genomischen dns-fragmenten oder ests kodierten (poly)peptiden binden
|
|
IT1307309B1
(it)
|
1999-12-30 |
2001-10-30 |
Enea Ente Nuove Tec |
Peptidi stabilizzanti, polipeptidi ed anticorpi che li comprendono.
|
|
AU5697001A
(en)
|
2000-03-31 |
2001-10-15 |
Purdue Research Foundation |
Method of treatment using ligand-immunogen conjugates
|
|
DE10037759A1
(de)
|
2000-08-03 |
2002-07-04 |
Gruenenthal Gmbh |
Screeningverfahren
|
|
US6333410B1
(en)
|
2000-08-18 |
2001-12-25 |
Immunogen, Inc. |
Process for the preparation and purification of thiol-containing maytansinoids
|
|
EP1998266A3
(en)
|
2001-02-19 |
2009-02-11 |
Merck Patent GmbH |
Method for identification of T-cell epitopes and use for preparing molecules with reduced immunogenicity
|
|
US20030087250A1
(en)
|
2001-03-14 |
2003-05-08 |
Millennium Pharmaceuticals, Inc. |
Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
|
|
RU2316349C2
(ru)
|
2001-05-02 |
2008-02-10 |
Пердью Рисерч Фаундейшн |
Лечение и диагностика заболеваний, опосредованных макрофагами
|
|
US6441163B1
(en)
|
2001-05-31 |
2002-08-27 |
Immunogen, Inc. |
Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents
|
|
US6716821B2
(en)
|
2001-12-21 |
2004-04-06 |
Immunogen Inc. |
Cytotoxic agents bearing a reactive polyethylene glycol moiety, cytotoxic conjugates comprising polyethylene glycol linking groups, and methods of making and using the same
|
|
US7314974B2
(en)
|
2002-02-21 |
2008-01-01 |
Monsanto Technology, Llc |
Expression of microbial proteins in plants for production of plants with improved properties
|
|
WO2003074704A1
(fr)
|
2002-03-01 |
2003-09-12 |
Japan Envirochemicals, Ltd. |
Proteines capables de se lier aux hormones sexuelles feminines et procede de preparation
|
|
NZ535425A
(en)
|
2002-03-13 |
2008-05-30 |
Biogen Idec Inc |
Anti-alphavbeta6 antibodies
|
|
EP2090591A3
(en)
|
2002-04-22 |
2009-10-28 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Antibodies, recombinant antibodies, recombinant antibody fragments and fusions mediated plant disease resistance against fungi
|
|
AU2003295411A1
(en)
|
2002-11-07 |
2004-06-03 |
Celltech R & D |
Human monoclonal antibodies to heparanase
|
|
EP1481993A1
(en)
|
2003-05-28 |
2004-12-01 |
Xerion Pharmaceuticals AG |
Modulation of the poliovirus receptor function
|
|
US20080131366A1
(en)
|
2003-03-17 |
2008-06-05 |
Manohar Ratnam |
Folate Receptor Gene Modulation For Cancer Diagnosis And Therapy
|
|
US20050255114A1
(en)
|
2003-04-07 |
2005-11-17 |
Nuvelo, Inc. |
Methods and diagnosis for the treatment of preeclampsia
|
|
US20050025763A1
(en)
|
2003-05-08 |
2005-02-03 |
Protein Design Laboratories, Inc. |
Therapeutic use of anti-CS1 antibodies
|
|
KR101412271B1
(ko)
|
2003-05-09 |
2014-06-25 |
듀크 유니버시티 |
Cd20-특이적 항체 및 이를 이용한 방법
|
|
MX342007B
(es)
|
2003-05-14 |
2016-09-09 |
Immunogen Inc |
Composicion de farmaco conjugado.
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
US7276497B2
(en)
|
2003-05-20 |
2007-10-02 |
Immunogen Inc. |
Cytotoxic agents comprising new maytansinoids
|
|
RS20150135A1
(sr)
|
2003-05-30 |
2015-08-31 |
Genentech Inc. |
Tretman sa anti-vegf antitelima
|
|
MXPA05014153A
(es)
|
2003-07-02 |
2006-07-03 |
Genentech Inc |
Composiciones y metodoso para el diagnostico y tratamiento de tumor.
|
|
WO2005054469A1
(en)
|
2003-12-05 |
2005-06-16 |
Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Health |
Anti-sars monoclonal antibodies
|
|
WO2005080431A2
(en)
|
2004-02-12 |
2005-09-01 |
Morphotek, Inc. |
Monoclonal antibodies that specifically bind to folate receptor alpha
|
|
EP2259063B1
(en)
|
2004-04-27 |
2012-05-23 |
Galapagos N.V. |
Compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts
|
|
AU2005279347A1
(en)
|
2004-08-30 |
2006-03-09 |
Lonza Biologics Plc. |
Affinity- plus ion exchange- chromatography for purifying antibodies
|
|
US8772269B2
(en)
|
2004-09-13 |
2014-07-08 |
Eisai R&D Management Co., Ltd. |
Use of sulfonamide-including compounds in combination with angiogenesis inhibitors
|
|
US7776869B2
(en)
|
2004-10-18 |
2010-08-17 |
Amgen Inc. |
Heteroaryl-substituted alkyne compounds and method of use
|
|
US7780963B2
(en)
|
2004-10-25 |
2010-08-24 |
Merck & Co., Inc. |
Anti-ADDL antibodies and uses thereof
|
|
EP2562259B1
(en)
|
2004-12-21 |
2016-07-06 |
Monsanto Technology LLC |
Transgenic plants with enhanced agronomic traits
|
|
WO2006071877A2
(en)
|
2004-12-27 |
2006-07-06 |
Progenics Pharmaceuticals (Nevada), Inc. |
Orally deliverable and anti-toxin antibodies and methods for making and using them
|
|
US20080181888A1
(en)
|
2004-12-31 |
2008-07-31 |
Ambrose Christine M |
Polypeptides That Bind Br3 and Uses Thereof
|
|
EP1850866A4
(en)
|
2005-01-27 |
2009-07-08 |
Univ California |
MONOCLONAL THERAPEUTIC ANTIBODIES FOR THE NEUTRALIZATION OF BOTULIN NEUROTOXINES
|
|
CA2599301A1
(en)
*
|
2005-02-28 |
2006-08-31 |
Eisai R & D Management Co., Ltd. |
Novel use of sulfonamide compound in combination with angiogenesis inhibitor
|
|
CA2602777C
(en)
|
2005-03-25 |
2018-12-11 |
Tolerrx, Inc. |
Gitr binding molecules and uses therefor
|
|
US7608413B1
(en)
|
2005-03-25 |
2009-10-27 |
Celera Corporation |
Kidney disease targets and uses thereof
|
|
WO2006105141A1
(en)
|
2005-03-30 |
2006-10-05 |
Purdue Research Foundation |
Method for cancer prognosis using cellular folate vitamin receptor quantification
|
|
JP2009521206A
(ja)
|
2005-04-22 |
2009-06-04 |
モルフォテック、インク. |
免疫エフェクター活性を有する葉酸受容体アルファ陽性細胞に内部移行する抗体
|
|
EP1888639A1
(en)
|
2005-05-12 |
2008-02-20 |
Oncotherapy Science, Inc. |
Methods for damaging cells using effector function of anti-dsc2 antibody
|
|
AU2006249087B2
(en)
|
2005-05-20 |
2012-05-17 |
Lonza Biologics Plc |
High-level expression of recombinant antibody in a mammalian host cell
|
|
JP2009508467A
(ja)
|
2005-05-24 |
2009-03-05 |
アベスタゲン リミテッド |
B細胞リンパ腫の治療のためのcd20に対するモノクローナル抗体を生成する方法
|
|
WO2007006041A2
(en)
|
2005-07-05 |
2007-01-11 |
Purdue Research Foundation |
Imaging and therapeutic method using monocytes
|
|
US7521195B1
(en)
|
2005-07-21 |
2009-04-21 |
Celera Corporation |
Lung disease targets and uses thereof
|
|
US8124076B2
(en)
|
2005-08-18 |
2012-02-28 |
Ramot At Tel Aviv University Ltd. |
Single chain antibodies against β-amyloid peptide
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
JP4938263B2
(ja)
|
2005-08-19 |
2012-05-23 |
独立行政法人農業生物資源研究所 |
一本鎖抗体によるサイトゾルタンパク質の機能阻害法およびその利用
|
|
ME02705B
(me)
|
2005-08-31 |
2017-10-20 |
Merck Sharp & Dohme |
Inženjerisana anti-il-23 antitela
|
|
ES2543341T3
(es)
|
2005-09-13 |
2015-08-18 |
National Research Council Of Canada |
Métodos y composiciones para modular la actividad de células tumorales
|
|
US20090162374A1
(en)
*
|
2005-09-14 |
2009-06-25 |
Geraghty Daniel E |
Specific removal of activated immune cells
|
|
US20070099251A1
(en)
|
2005-10-17 |
2007-05-03 |
Institute For Systems Biology |
Tissue-and serum-derived glycoproteins and methods of their use
|
|
EP1790664A1
(en)
|
2005-11-24 |
2007-05-30 |
Ganymed Pharmaceuticals AG |
Monoclonal antibodies against claudin-18 for treatment of cancer
|
|
EP3441403A1
(en)
|
2005-12-20 |
2019-02-13 |
SBI Biotech Co., Ltd. |
Anti-ilt7 antibody
|
|
MX2008012023A
(es)
|
2006-03-21 |
2008-10-01 |
Wyeth Corp |
Metodos para prevenir y tratar enfermedades amiloidogenicas.
|
|
US8486412B2
(en)
|
2006-06-01 |
2013-07-16 |
Mayo Foundation For Medical Education And Research |
Immunity to folate receptors
|
|
CN101490084A
(zh)
*
|
2006-06-06 |
2009-07-22 |
健泰科生物技术公司 |
抗dll4抗体及其使用方法
|
|
WO2007147265A1
(en)
|
2006-06-23 |
2007-12-27 |
Alethia Biotherapeutics Inc. |
Polynucleotides and polypeptide sequences involved in cancer
|
|
US7910702B2
(en)
|
2006-07-28 |
2011-03-22 |
The Governors Of The University Of Alberta |
Recombinant antibodies to sclerotinia antigens
|
|
CA2660286A1
(en)
|
2006-08-09 |
2008-02-21 |
Homestead Clinical Corporation |
Organ-specific proteins and methods of their use
|
|
KR101625961B1
(ko)
|
2006-09-08 |
2016-05-31 |
애브비 바하마스 리미티드 |
인터루킨-13 결합 단백질
|
|
EP1900752A1
(en)
|
2006-09-15 |
2008-03-19 |
DOMPE' pha.r.ma s.p.a. |
Human anti-folate receptor alpha antibodies and antibody fragments for the radioimmunotherapy of ovarian carcinoma
|
|
WO2008047723A1
(fr)
|
2006-10-12 |
2008-04-24 |
Forerunner Pharma Research Co., Ltd. |
Diagnostic et traitement du cancer à l'aide d'un anticorps anti-ereg
|
|
CA2670471A1
(en)
*
|
2006-11-22 |
2008-06-05 |
Adnexus, A Bristol-Myers Squibb R&D Company (A Delaware Corporation) |
Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including igf-ir
|
|
CA2672581A1
(en)
|
2006-12-14 |
2008-06-19 |
Forerunner Pharma Research Co., Ltd. |
Anti-claudin 3 monoclonal antibody and treatment and diagnosis of cancer using the same
|
|
KR101378302B1
(ko)
|
2006-12-20 |
2014-03-28 |
엠엠알글로벌, 인코포레이티드 |
항체 및 이들의 제조 및 사용 방법
|
|
US20080227704A1
(en)
|
2006-12-21 |
2008-09-18 |
Kamens Joanne S |
CXCL13 binding proteins
|
|
US7691980B2
(en)
|
2007-01-09 |
2010-04-06 |
Bio-Rad Laboratories, Inc. |
Enhanced capacity and purification of antibodies by mixed mode chromatography in the presence of aqueous-soluble nonionic organic polymers
|
|
WO2008101231A2
(en)
|
2007-02-16 |
2008-08-21 |
Endocyte, Inc. |
Methods and compositions for treating and diagnosing kidney disease
|
|
US9216228B2
(en)
|
2007-02-16 |
2015-12-22 |
KTB Tumorforschungsgesellschaft MBM |
Receptor and antigen targeted prodrug
|
|
CN101663320A
(zh)
|
2007-02-23 |
2010-03-03 |
先灵公司 |
工程改造的抗IL-23p19抗体
|
|
WO2008145136A1
(en)
|
2007-05-30 |
2008-12-04 |
Aarhus Universitet |
Stat3 inactivation by inhibition of the folate receptor pathway
|
|
US9138484B2
(en)
|
2007-06-25 |
2015-09-22 |
Endocyte, Inc. |
Conjugates containing hydrophilic spacer linkers
|
|
CN101139613B
(zh)
|
2007-08-01 |
2011-06-08 |
姜荣锡 |
抗肿瘤二元多肽及其应用与制备方法
|
|
TWI580694B
(zh)
|
2007-11-30 |
2017-05-01 |
建南德克公司 |
抗-vegf抗體
|
|
JP2011506371A
(ja)
|
2007-12-12 |
2011-03-03 |
ピンチェル ソチエタ・レスポンサビリタ・リミタータ |
抗Fasリガンド抗体を含有する天疱瘡の治療薬
|
|
PT2227549E
(pt)
|
2007-12-21 |
2015-10-08 |
Novartis Ag |
Sistema de seleção para cultura de células eucarióticas com base num gene de recetor de folato ligado à membrana
|
|
HRP20150143T1
(hr)
|
2007-12-26 |
2015-04-10 |
Biotest Ag |
Imunokonjugati koji ciljaju na cd138 i njihova upotreba
|
|
CA2711557A1
(en)
|
2008-01-11 |
2009-07-16 |
The University Of Tokyo |
Anti-cldn6 antibody
|
|
WO2009092014A1
(en)
|
2008-01-18 |
2009-07-23 |
Gagnon Peter S |
Enhanced purification of antibodies and antibody fragments by apatite chromatography
|
|
WO2009094456A2
(en)
*
|
2008-01-22 |
2009-07-30 |
Johns Hopkins University |
Use of high-dose, post-transplantation oxazaphosphorine drugs for reduction of transplant rejection
|
|
WO2009132081A2
(en)
|
2008-04-24 |
2009-10-29 |
The Research Foundation Of State University Of New York |
Monoclonal antibody-based targeting of folate receptors
|
|
CN104524592B
(zh)
|
2008-04-30 |
2018-06-05 |
伊缪诺金公司 |
交联剂和它们的用途
|
|
CN102083461B
(zh)
|
2008-04-30 |
2014-09-17 |
伊缪诺金公司 |
有效的偶联物和亲水性连接体
|
|
US8383351B2
(en)
|
2008-06-11 |
2013-02-26 |
Oxford Brookes University |
Antibody to inhibin/ activin β-B subunit
|
|
AU2009293140A1
(en)
|
2008-09-17 |
2010-03-25 |
Endocyte, Inc. |
Folate receptor binding conjugates of antifolates
|
|
WO2010033913A1
(en)
|
2008-09-22 |
2010-03-25 |
Icb International, Inc. |
Antibodies, analogs and uses thereof
|
|
CN101440130B
(zh)
|
2008-11-21 |
2011-07-27 |
中国人民解放军第四军医大学 |
一种抗人IL-13Rα2单克隆抗体的重链和轻链的可变区
|
|
EA201100984A1
(ru)
|
2008-12-19 |
2012-01-30 |
Грэйсуэй Фармасьютикалс, Ллс |
Композиции с более низким содержанием имиквимода и короткие режимы дозирования для лечения актинического кератоза
|
|
EP2995953B1
(en)
|
2009-03-24 |
2017-11-29 |
Biocept, Inc. |
Devices and methods of cell capture and analysis
|
|
JP5769316B2
(ja)
|
2009-08-06 |
2015-08-26 |
イムナス・ファーマ株式会社 |
Aβオリゴマーに特異的に結合する抗体およびその利用
|
|
BR112012007821A2
(pt)
|
2009-10-09 |
2017-05-30 |
Sanofi Sa |
polipeptídeos para ligação ao "receptor de produtos finais de glicação avançada" bem como composições e métodos envolvendo os mesmos
|
|
EP2526118A4
(en)
*
|
2010-01-21 |
2013-11-13 |
Immunogen Inc |
COMPOSITIONS AND METHOD FOR THE TREATMENT OF EGG CANCER
|
|
WO2011100398A1
(en)
|
2010-02-10 |
2011-08-18 |
Immunogen, Inc. |
Cd20 antibodies and uses thereof
|
|
CN103237810A
(zh)
*
|
2010-02-23 |
2013-08-07 |
霍夫曼-拉罗奇有限公司 |
用于治疗卵巢癌的抗血管发生疗法
|
|
SMT201700139T1
(it)
*
|
2010-02-24 |
2017-05-08 |
Immunogen Inc |
Immunoconiugati contro il recettore 1 del folato e relativi usi
|
|
JP6093692B2
(ja)
|
2010-03-24 |
2017-03-08 |
ジェネンテック, インコーポレイテッド |
抗lrp6抗体
|
|
EP2558122A4
(en)
*
|
2010-04-15 |
2014-03-05 |
Vegenics Pty Ltd |
COMBINATION TREATMENT WITH VEGF-C ANTAGONISTS
|
|
EP2629798A4
(en)
|
2010-10-20 |
2014-05-28 |
Morphotek Inc |
GLYCOFORMS OF ANTI-RECEPTOR ANTIBODY-ALPHA FOLATE (ANTI-FRA)
|
|
JP6224456B2
(ja)
|
2010-11-05 |
2017-11-01 |
モルフォテック、インク. |
葉酸受容体アルファ発現癌の診断および予後マーカーとしての葉酸受容体アルファ
|
|
EP2667877B1
(en)
*
|
2011-01-26 |
2018-03-07 |
Allergan, Inc. |
Androgen composition for treating an ophthalmic condition
|
|
CA2831562A1
(en)
|
2011-03-29 |
2012-10-04 |
Immunogen, Inc. |
Process for manufacturing conjugates of improved homogeneity
|
|
EA201991268A3
(ru)
|
2011-03-29 |
2020-01-31 |
Иммуноджен, Инк. |
Получение конъюгатов "майтансиноид-антитело" одностадийным способом
|
|
CN114441757A
(zh)
|
2011-04-01 |
2022-05-06 |
伊缪诺金公司 |
用于增加folr1癌症治疗的功效的方法
|
|
US20120282282A1
(en)
|
2011-04-04 |
2012-11-08 |
Immunogen, Inc. |
Methods for Decreasing Ocular Toxicity of Antibody Drug Conjugates
|
|
US9156854B2
(en)
*
|
2011-04-18 |
2015-10-13 |
Immunogen, Inc. |
Maytansinoid derivatives with sulfoxide linker
|
|
EP2524929A1
(en)
|
2011-05-17 |
2012-11-21 |
Sanofi |
Use of anti-CD19 maytansinoid immunoconjugate antibody for the treatment of CD19+ B-cell malignancies syptoms
|
|
JP6220333B2
(ja)
|
2011-07-15 |
2017-10-25 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
抗葉酸受容体アルファ抗体およびその使用
|
|
US9296819B2
(en)
|
2012-06-12 |
2016-03-29 |
Promis Neurosciences Inc. |
Antibodies and conjugates that target misfolded prion protein
|
|
MX362514B
(es)
|
2012-08-31 |
2019-01-22 |
Immunogen Inc |
Kits y ensayos de diagnostico para la deteccion del receptor 1 de folato.
|
|
WO2014055842A1
(en)
|
2012-10-04 |
2014-04-10 |
Immunogen, Inc. |
Process for preparing stable antibody maytansinoid conjugates
|
|
EP2930240B1
(en)
|
2012-12-07 |
2018-08-01 |
Kyowa Hakko Kirin Co., Ltd. |
Anti-folr1 antibody
|
|
US9415118B2
(en)
*
|
2013-03-13 |
2016-08-16 |
Novartis Ag |
Antibody drug conjugates
|
|
EA032775B1
(ru)
*
|
2013-04-08 |
2019-07-31 |
Берг Ллк |
Способы лечения злокачественной опухоли с использованием комбинированной терапии с коферментом q10
|
|
KR20240068778A
(ko)
|
2013-05-14 |
2024-05-17 |
이뮤노젠 아이엔씨 |
항-folr1 면역접합체 투약 섭생
|
|
WO2014205342A2
(en)
*
|
2013-06-20 |
2014-12-24 |
Morphotek, Inc. |
Methods for treatment of ovarian cancer
|
|
SG11201601037YA
(en)
|
2013-08-30 |
2016-03-30 |
Immunogen Inc |
Antibodies and assays for detection of folate receptor 1
|
|
SG10201907042PA
(en)
*
|
2013-10-08 |
2019-09-27 |
Immunogen Inc |
Anti-folr1 immunoconjugate dosing regimens
|
|
US20150297744A1
(en)
|
2014-03-28 |
2015-10-22 |
Immunogen, Inc. |
Anti-FOLR1 Immunoconjugate Dosing Regimens
|
|
JP6880006B2
(ja)
*
|
2015-09-17 |
2021-06-02 |
イミュノジェン, インコーポレイテッド |
抗folr1免疫複合体を含む治療組み合わせ
|