|
US5585A
(en)
|
|
1848-05-16 |
|
Churn |
|
US5807A
(en)
|
|
1848-09-26 |
|
Brake fob cabs |
|
US89A
(en)
|
|
1836-11-26 |
|
Side-saddle |
|
US498A
(en)
|
|
1837-12-01 |
|
Improvement in mode of constructing saw-cylinders for cotton-gins |
|
US715A
(en)
|
|
1838-04-28 |
|
Improvement in water-wheels |
|
US5258A
(en)
|
|
1847-08-28 |
|
Cooking-stove |
|
US4179337A
(en)
|
1973-07-20 |
1979-12-18 |
Davis Frank F |
Non-immunogenic polypeptides
|
|
JPS6023084B2
(ja)
|
1979-07-11 |
1985-06-05 |
味の素株式会社 |
代用血液
|
|
US4444887A
(en)
|
1979-12-10 |
1984-04-24 |
Sloan-Kettering Institute |
Process for making human antibody producing B-lymphocytes
|
|
US6872868B1
(en)
|
1981-06-12 |
2005-03-29 |
Ohio University |
Transgenic mammals
|
|
US4714681A
(en)
|
1981-07-01 |
1987-12-22 |
The Board Of Reagents, The University Of Texas System Cancer Center |
Quadroma cells and trioma cells and methods for the production of same
|
|
US4474893A
(en)
|
1981-07-01 |
1984-10-02 |
The University of Texas System Cancer Center |
Recombinant monoclonal antibodies
|
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
|
US4640835A
(en)
|
1981-10-30 |
1987-02-03 |
Nippon Chemiphar Company, Ltd. |
Plasminogen activator derivatives
|
|
US4716111A
(en)
|
1982-08-11 |
1987-12-29 |
Trustees Of Boston University |
Process for producing human antibodies
|
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
|
US4496689A
(en)
|
1983-12-27 |
1985-01-29 |
Miles Laboratories, Inc. |
Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
|
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
|
DE3675588D1
(de)
|
1985-06-19 |
1990-12-20 |
Ajinomoto Kk |
Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist.
|
|
US4965198A
(en)
|
1985-12-24 |
1990-10-23 |
Konica Corporation |
Monoclonal antibody and method of manufacturing hybridoma producing the same
|
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
IN164232B
(enExample)
|
1986-04-11 |
1989-02-04 |
Hoechst India |
|
|
US4695198A
(en)
|
1986-05-23 |
1987-09-22 |
Chevron Research Company |
Lip-type sealing system for a removable bottom founded structure
|
|
US4791192A
(en)
|
1986-06-26 |
1988-12-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified protein with polyethyleneglycol
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
US5059680A
(en)
|
1986-11-24 |
1991-10-22 |
Centocor, Inc. |
Method of isolating ca 125 antigen
|
|
US5091513A
(en)
|
1987-05-21 |
1992-02-25 |
Creative Biomolecules, Inc. |
Biosynthetic antibody binding sites
|
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
|
CA1340927C
(en)
|
1987-10-09 |
2000-03-14 |
Peter S. Linsley |
Method for increasing the sensitivity of assays for target ligand
|
|
IT1212041B
(it)
|
1987-11-02 |
1989-11-08 |
Fidia Farmaceutici |
Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche
|
|
JPH02486A
(ja)
|
1987-11-13 |
1990-01-05 |
Mect Corp |
遊離ｎ−アセチルノイラミン酸を認識するモノクローナル抗体
|
|
US4978745A
(en)
|
1987-11-23 |
1990-12-18 |
Centocor, Inc. |
Immunoreactive heterochain antibodies
|
|
US4975369A
(en)
|
1988-04-21 |
1990-12-04 |
Eli Lilly And Company |
Recombinant and chimeric KS1/4 antibodies directed against a human adenocarcinoma antigen
|
|
US4925648A
(en)
|
1988-07-29 |
1990-05-15 |
Immunomedics, Inc. |
Detection and treatment of infectious and inflammatory lesions
|
|
US5601819A
(en)
|
1988-08-11 |
1997-02-11 |
The General Hospital Corporation |
Bispecific antibodies for selective immune regulation and for selective immune cell binding
|
|
AU4308689A
(en)
|
1988-09-02 |
1990-04-02 |
Protein Engineering Corporation |
Generation and selection of recombinant varied binding proteins
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
ES2096590T3
(es)
|
1989-06-29 |
1997-03-16 |
Medarex Inc |
Reactivos biespecificos para la terapia del sida.
|
|
US5413923A
(en)
|
1989-07-25 |
1995-05-09 |
Cell Genesys, Inc. |
Homologous recombination for universal donor cells and chimeric mammalian hosts
|
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
|
AU7247191A
(en)
|
1990-01-11 |
1991-08-05 |
Molecular Affinities Corporation |
Production of antibodies using gene libraries
|
|
US5780225A
(en)
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
|
WO1991010741A1
(en)
|
1990-01-12 |
1991-07-25 |
Cell Genesys, Inc. |
Generation of xenogeneic antibodies
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9012995D0
(en)
|
1990-06-11 |
1990-08-01 |
Celltech Ltd |
Multivalent antigen-binding proteins
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
|
ATE158021T1
(de)
|
1990-08-29 |
1997-09-15 |
Genpharm Int |
Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5698426A
(en)
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
|
DK0553244T4
(da)
|
1990-10-05 |
2005-08-01 |
Celldex Therapeutics Inc |
Målrettet immunostimulering med bispecifikke reagenser
|
|
EP0557300B1
(en)
|
1990-10-29 |
1997-11-19 |
Chiron Corporation |
Bispecific antibodies, method of production, and uses thereof
|
|
DK0564531T3
(da)
|
1990-12-03 |
1998-09-28 |
Genentech Inc |
Berigelsesfremgangsmåde for variantproteiner med ændrede bindingsegenskaber
|
|
ES2223040T3
(es)
|
1991-04-10 |
2005-02-16 |
The Scripps Research Institute |
Bibliotecas de receptor heterodimerilo que usan fagemidos.
|
|
WO1992019973A1
(en)
|
1991-04-26 |
1992-11-12 |
Surface Active Limited |
Novel antibodies, and methods for their use
|
|
EP0519596B1
(en)
|
1991-05-17 |
2005-02-23 |
Merck & Co. Inc. |
A method for reducing the immunogenicity of antibody variable domains
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
AU3178993A
(en)
|
1991-11-25 |
1993-06-28 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
|
US5932448A
(en)
|
1991-11-29 |
1999-08-03 |
Protein Design Labs., Inc. |
Bispecific antibody heterodimers
|
|
DE69233745D1
(de)
|
1991-12-02 |
2008-10-23 |
Cambridge Antibody Tech |
Herstellung von Autoantikörpern auf Phagenoberflächen ausgehend von Antikörpersegmentbibliotheken
|
|
EP0627940B1
(en)
|
1992-03-05 |
2003-05-07 |
Board of Regents, The University of Texas System |
Use of immunoconjugates for the diagnosis and/or therapy of vascularized tumors
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
CA2076465C
(en)
|
1992-03-25 |
2002-11-26 |
Ravi V. J. Chari |
Cell binding agent conjugates of analogues and derivatives of cc-1065
|
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
US5951983A
(en)
|
1993-03-05 |
1999-09-14 |
Universite Catholique De Louvain |
Methods of inhibiting T cell mediated immune responses with humanized LO-CD2A-specific antibodies
|
|
US20030108548A1
(en)
|
1993-06-01 |
2003-06-12 |
Bluestone Jeffrey A. |
Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies
|
|
WO1995015982A2
(en)
|
1993-12-08 |
1995-06-15 |
Genzyme Corporation |
Process for generating specific antibodies
|
|
AU1736495A
(en)
|
1994-01-31 |
1995-08-15 |
Trustees Of Boston University |
Polyclonal antibody libraries
|
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
|
US5786464C1
(en)
|
1994-09-19 |
2012-04-24 |
Gen Hospital Corp |
Overexpression of mammalian and viral proteins
|
|
US5919652A
(en)
|
1994-11-09 |
1999-07-06 |
The Regents Of The University Of California |
Nucleic acid molecules comprising the prostate specific antigen (PSA) promoter and uses thereof
|
|
US5710038A
(en)
|
1994-11-25 |
1998-01-20 |
Universite De Montreal |
Primary cultures of normal and tumoral human ovarian epithelium
|
|
US5811510A
(en)
|
1995-04-14 |
1998-09-22 |
General Hospital Corporation |
Biodegradable polyacetal polymers and methods for their formation and use
|
|
DE69637481T2
(de)
|
1995-04-27 |
2009-04-09 |
Amgen Fremont Inc. |
Aus immunisierten Xenomäusen stammende menschliche Antikörper gegen IL-8
|
|
AU2466895A
(en)
|
1995-04-28 |
1996-11-18 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5733920A
(en)
|
1995-10-31 |
1998-03-31 |
Mitotix, Inc. |
Inhibitors of cyclin dependent kinases
|
|
JP2978435B2
(ja)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
アクリロキシプロピルシランの製造方法
|
|
US5849733A
(en)
|
1996-05-10 |
1998-12-15 |
Bristol-Myers Squibb Co. |
2-thio or 2-oxo flavopiridol analogs
|
|
CA2259501A1
(en)
|
1996-07-03 |
1998-01-08 |
Millennium Pharmaceuticals, Inc. |
Detection of cancer by assaying for cancer-specific antigens having linked oligosaccharides which are at least triantennary
|
|
US6114148C1
(en)
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
|
US6348584B1
(en)
|
1996-10-17 |
2002-02-19 |
John Edward Hodgson |
Fibronectin binding protein compounds
|
|
DE69738539T2
(de)
|
1996-12-03 |
2009-03-26 |
Amgen Fremont Inc. |
Vollkommen humane Antikörper die EGFR binden
|
|
ES2172149T3
(es)
|
1997-04-14 |
2002-09-16 |
Micromet Ag |
Nuevo metodo para la produccion de receptores de antigeno anti-humano y sus usos.
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
CA2293632C
(en)
|
1997-06-12 |
2011-11-29 |
Research Corporation Technologies, Inc. |
Artificial antibody polypeptides
|
|
JP2001516766A
(ja)
|
1997-09-19 |
2001-10-02 |
デイナ−ファーバー キャンサー インスティチュート，インコーポレイテッド |
免疫反応の細胞内発現抗体仲介制御
|
|
WO1999037751A1
(en)
|
1998-01-23 |
1999-07-29 |
Imclone Systems Incorporated |
Purified populations of stem cells
|
|
US6410319B1
(en)
|
1998-10-20 |
2002-06-25 |
City Of Hope |
CD20-specific redirected T cells and their use in cellular immunotherapy of CD20+ malignancies
|
|
US20030170249A1
(en)
|
1999-02-19 |
2003-09-11 |
Hakomori Sen-Itiroh |
Vaccines directed to cancer-associated carbohydrate antigens
|
|
US20020012660A1
(en)
|
1999-03-04 |
2002-01-31 |
Alan Colman |
Method of preparing a somatic cells for nuclear transfer
|
|
GB2344886B
(en)
|
1999-03-10 |
2000-11-01 |
Medical Res Council |
Selection of intracellular immunoglobulins
|
|
EP1196031A1
(en)
|
1999-06-16 |
2002-04-17 |
Biocrystal Limited |
Vaccine formulations and methods for immunizing an individual against shed antigen-specific b cells
|
|
DE60043784D1
(de)
|
1999-12-06 |
2010-03-18 |
Agensys Inc |
Serpentinetransmembranrezeptoren exprimiert in menschlichem prostatakrebs und ihre verwendungen
|
|
WO2001043778A1
(en)
|
1999-12-17 |
2001-06-21 |
Gene Therapy Systems, Inc. |
Use of cationic lipids for intracellular protein delivery
|
|
US20030008813A1
(en)
|
1999-12-17 |
2003-01-09 |
Felgner Philip L. |
Intracellular protein delivery compositions and methods of use
|
|
WO2001075177A2
(en)
|
2000-04-03 |
2001-10-11 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Tumor markers in ovarian cancer
|
|
IT1317922B1
(it)
|
2000-10-24 |
2003-07-15 |
S I S S A Scuola Internaz Supe |
Metodo per identificare in vivo epitopi intracellulari.
|
|
US7446179B2
(en)
|
2000-11-07 |
2008-11-04 |
City Of Hope |
CD19-specific chimeric T cell receptor
|
|
AU2002338446A1
(en)
|
2001-01-23 |
2002-11-05 |
University Of Rochester Medical Center |
Methods of producing or identifying intrabodies in eukaryotic cells
|
|
AU2002233619A1
(en)
|
2001-02-26 |
2002-09-12 |
Zur Pierre Beserman |
Systems devices and methods for intrabody targeted delivery and reloading of therapeutic agents
|
|
GB0108165D0
(en)
|
2001-03-31 |
2001-05-23 |
Univ Manchester |
Intracellular analysis
|
|
AU2002256390B2
(en)
|
2001-04-30 |
2007-08-30 |
City Of Hope |
Chimeric immunoreceptor useful in treating human cancers
|
|
US20090257994A1
(en)
|
2001-04-30 |
2009-10-15 |
City Of Hope |
Chimeric immunoreceptor useful in treating human cancers
|
|
US7514537B2
(en)
|
2001-04-30 |
2009-04-07 |
City Of Hope |
Chimeric immunoreceptor useful in treating human gliomas
|
|
WO2002088351A1
(en)
|
2001-04-30 |
2002-11-07 |
Rbc Biotechnology, Inc. |
Modified organs and cells for xenotransplantation
|
|
KR100486784B1
(ko)
|
2001-05-22 |
2005-04-29 |
김하형 |
솔비나무로 부터 추출된 렉틴 단백질, 그의 제조방법 및용도
|
|
US20020192231A1
(en)
|
2001-05-24 |
2002-12-19 |
Immucom Inc. |
Method of increasing anti-neuGc antibody levels in blood
|
|
US6814734B2
(en)
|
2001-06-18 |
2004-11-09 |
Sdgi Holdings, Inc, |
Surgical instrumentation and method for forming a passage in bone having an enlarged cross-sectional portion
|
|
US20060127893A1
(en)
|
2001-07-19 |
2006-06-15 |
Stefan Ewert |
Modification of human variable domains
|
|
WO2003014960A2
(en)
|
2001-08-03 |
2003-02-20 |
Medical Research Council |
Method of identifying a consensus sequence for intracellular antibodies
|
|
AU2002336981A1
(en)
|
2001-08-17 |
2003-03-03 |
Charite |
Glycoconjugates of sialic acid derivates, methods for their production and use thereof
|
|
EP1442063A2
(de)
|
2001-11-09 |
2004-08-04 |
Hexal Biotech Forschungsgmbh |
Anti-n-glykolyl-neuraminsäure-antikörper und ihre verwendung zur bestimmung von glykoproteinen
|
|
EP2277889B1
(en)
|
2001-12-21 |
2014-07-09 |
Human Genome Sciences, Inc. |
Fusion proteins of albumin and interferon beta
|
|
KR20060111716A
(ko)
|
2002-01-22 |
2006-10-27 |
워너-램버트 캄파니 엘엘씨 |
2-(피리딘-2-일아미노)-피리도[2,3-ｄ]피리미딘-7-온
|
|
GB0201611D0
(en)
|
2002-01-24 |
2002-03-13 |
Grosveld Frank |
Transgenic animal
|
|
GB0226723D0
(en)
|
2002-11-15 |
2002-12-24 |
Medical Res Council |
Antibodies for in vitro use
|
|
AU2003219277A1
(en)
|
2002-03-14 |
2003-09-29 |
Medical Research Council |
Intracellular antibodies
|
|
GB0226727D0
(en)
|
2002-11-15 |
2002-12-24 |
Medical Res Council |
Intrabodies
|
|
WO2003086276A2
(en)
|
2002-04-05 |
2003-10-23 |
Selective Genetics, Inc. |
Compositions and methods for portal specific gene delivery and treatment of infection
|
|
PT2332989E
(pt)
|
2002-05-22 |
2015-08-05 |
Esbatech Alcon Biomed Res Unit |
Estruturas de imunoglobulina que demonstram estabilidade aumentada no ambiente intracelular e métodos de identificação das mesmas
|
|
US7119200B2
(en)
|
2002-09-04 |
2006-10-10 |
Schering Corporation |
Pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
WO2004046188A2
(en)
|
2002-11-15 |
2004-06-03 |
Medical Research Council |
Anti-activated ras antibodies
|
|
GB0226731D0
(en)
|
2002-11-15 |
2002-12-24 |
Medical Res Council |
Method for generating immunoglobulin genes
|
|
GB0226729D0
(en)
|
2002-11-15 |
2002-12-24 |
Medical Res Council |
Intracellular antibodies
|
|
ITRM20020588A1
(it)
|
2002-11-21 |
2004-05-22 |
Lay Line Genomics Spa |
Metodo per isolare anticorpi intracellulari neutralizzanti di interazioni proteiche.
|
|
EP1482309A1
(en)
|
2003-05-07 |
2004-12-01 |
Institut Curie |
Means for detecting protein conformation and applications thereof
|
|
PL1648889T3
(pl)
|
2003-07-11 |
2009-03-31 |
Warner Lambert Co |
Sól izetionian selektywnego inhibitora CDK4
|
|
EP1651955A4
(en)
|
2003-07-15 |
2007-11-21 |
Univ California |
PROCESS FOR THE DETECTION AND ANALYSIS OF N-GLYCOLYLNEURAMIC ACID (NEU5GC) IN BIOLOGICAL MATERIALS
|
|
ITMI20031909A1
(it)
|
2003-10-03 |
2005-04-04 |
Keryos Spa |
Linee cellulari di mammifero modificate per la produzione di glicoproteine ricombinanti.
|
|
CA2550933A1
(en)
|
2003-12-22 |
2005-07-14 |
Amgen Inc. |
Methods for identifying functional antibodies
|
|
JP2007527539A
(ja)
|
2004-03-05 |
2007-09-27 |
ザ スクリプス リサーチ インスティテュート |
ハイスループットグリカンマイクロアレイ
|
|
ES2379526T3
(es)
|
2004-04-30 |
2012-04-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anticuerpo anti-TfR
|
|
KR100620554B1
(ko)
|
2004-06-05 |
2006-09-06 |
한국생명공학연구원 |
Ｔａｇ-72에 대한 인간화 항체
|
|
WO2006002382A2
(en)
|
2004-06-24 |
2006-01-05 |
The Scripps Research Institute |
Arrays with cleavable linkers
|
|
US7638467B2
(en)
|
2004-08-03 |
2009-12-29 |
Intevep, S.A. |
Reversible gelling system and method using same during well treatments
|
|
EP2422811A2
(en)
|
2004-10-27 |
2012-02-29 |
MedImmune, LLC |
Modulation of antibody specificity by tailoring the affinity to cognate antigens
|
|
WO2006068758A2
(en)
|
2004-11-19 |
2006-06-29 |
The Scripps Research Institute |
Detection, prevention and treatment of breast cancer
|
|
EP1874816A4
(en)
|
2005-04-26 |
2010-08-25 |
Medimmune Inc |
MODULATION OF THE ANTIBODY EFFECTOR FUNCTION BY "HINGE" DOMENGINE ENGINEERING
|
|
WO2006117910A1
(ja)
|
2005-04-28 |
2006-11-09 |
Mochida Pharmaceutical Co., Ltd. |
抗血小板膜糖蛋白質ⅵモノクローナル抗体
|
|
AU2006254862B2
(en)
|
2005-06-08 |
2011-04-07 |
The Regents Of The University Of California |
Elimination of N-glycolylneuraminic acid from mammalian products for human use
|
|
CN101267841B
(zh)
|
2005-08-24 |
2012-10-10 |
免疫原公司 |
制备美登木素生物碱抗体缀合物的方法
|
|
DK2913343T3
(en)
|
2005-12-20 |
2018-11-26 |
Sbi Biotech Co Ltd |
Anti-ILT7 antibody
|
|
WO2007079448A2
(en)
|
2006-01-03 |
2007-07-12 |
University Of Georgia Research Foundation, Inc. |
Three component carbohydrate vaccine
|
|
ATE509027T1
(de)
|
2006-01-13 |
2011-05-15 |
Pasteur Institut |
Enzymatische synthese von grossen mengen von mucin glyconjugaten und deren immunogenische anwendungen
|
|
EP2004221A2
(en)
|
2006-03-23 |
2008-12-24 |
Novartis Pharma AG |
Anti-tumor cell antigen antibody therapeutics
|
|
EP2000802A4
(en)
|
2006-03-31 |
2009-04-15 |
Mochida Pharm Co Ltd |
NOVEL MARKER FOR PLATELET ACTIVATION AND METHOD FOR DETERMINING THE SAME
|
|
US20070265170A1
(en)
|
2006-05-15 |
2007-11-15 |
Ola Blixt |
Detection, prevention and treatment of ovarian cancer
|
|
GB0613209D0
(en)
*
|
2006-07-03 |
2006-08-09 |
Ucb Sa |
Methods
|
|
CA2665356C
(en)
|
2006-10-04 |
2017-10-31 |
Kobenhavns Universitet |
Generation of a cancer-specific immune response toward muc1 and cancer specific muc1 antibodies
|
|
US20100143371A1
(en)
|
2006-10-31 |
2010-06-10 |
Zhenping Zhu |
Intrabodies
|
|
US20100104572A1
(en)
|
2006-11-02 |
2010-04-29 |
Sylvie Luria |
Methods for screening for therapeutic molecules and use of the molecules therefrom
|
|
WO2009018438A1
(en)
|
2007-07-31 |
2009-02-05 |
Cornell Research Foundation, Inc. |
Protein discovery using intracellular ribosome display
|
|
EP2014302A1
(en)
|
2007-07-12 |
2009-01-14 |
Institut Curie |
An antibody specific for the Tn antigen for the treatment of cancer
|
|
WO2009035494A2
(en)
|
2007-07-30 |
2009-03-19 |
The Scripps Research Institute |
Methods for producing anti-glycan antibodies, vaccines and methods for treating cancer or infectious disease
|
|
FI20070853A0
(fi)
|
2007-11-09 |
2007-11-09 |
Glykos Finland Oy |
Glykaania sitovat monoklonaaliset vasta-aineet
|
|
EP2220122A2
(en)
|
2007-11-13 |
2010-08-25 |
Teva Biopharmaceuticals USA, Inc. |
Humanized antibodies against tl1a
|
|
WO2009091826A2
(en)
|
2008-01-14 |
2009-07-23 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods related to a human cd19-specific chimeric antigen receptor (h-car)
|
|
US8506966B2
(en)
|
2008-02-22 |
2013-08-13 |
Novartis Ag |
Adjuvanted influenza vaccines for pediatric use
|
|
US20120027813A1
(en)
|
2008-02-22 |
2012-02-02 |
Novartis Vaccines And Diagnostics Srl |
Adjuvanted influenza vaccines for pediatric use
|
|
US8298773B2
(en)
|
2008-05-02 |
2012-10-30 |
Marko Vuskovic |
Methods, assays and kits for cancer diagnosis and screening utilizing glycan-binding and glycan epitopes
|
|
EP2283862B1
(en)
|
2008-06-02 |
2018-08-08 |
The University of Tokyo |
Combination treatment of cancer comprising anti-mfg-e8 antibody
|
|
US20120039984A1
(en)
|
2008-07-03 |
2012-02-16 |
University Of Georgia Research Foundation, Inc. |
Glycopeptide and uses thereof
|
|
EP2143735A1
(en)
|
2008-07-10 |
2010-01-13 |
Institut Pasteur |
Variable domains of camelid heavy-chain antibodies directed against glial fibrillary acidic proteins
|
|
US20100009424A1
(en)
|
2008-07-14 |
2010-01-14 |
Natasha Forde |
Sonoporation systems and methods
|
|
FI20095418A0
(fi)
|
2009-04-16 |
2009-04-16 |
Suomen Punainen Risti Veripalv |
Kryptinen subpopulaatio
|
|
NZ591176A
(en)
|
2008-08-22 |
2012-11-30 |
Novartis Ag |
Pyrrolopyrimidine compounds as cdk inhibitors
|
|
CN102197131A
(zh)
|
2008-09-09 |
2011-09-21 |
加利福尼亚大学董事会 |
通过代谢竞争除去污染性的非人唾液酸
|
|
US20120045816A1
(en)
|
2008-09-09 |
2012-02-23 |
Sialix, Inc. |
Novel Glycosylated Polypeptides
|
|
PA8852901A1
(es)
|
2008-12-22 |
2010-07-27 |
Lilly Co Eli |
Inhibidores de proteina cinasa
|
|
US20100178292A1
(en)
|
2009-01-12 |
2010-07-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Cryptic glycan markers and applications thereof
|
|
US8669085B2
(en)
|
2009-02-05 |
2014-03-11 |
Ut-Battelle, Llc |
Transformation of gram positive bacteria by sonoporation
|
|
CA2762877A1
(en)
|
2009-05-28 |
2010-12-02 |
Mersana Therapeutics, Inc. |
Polyal drug conjugates comprising variable rate-releasing linkers
|
|
US8399624B1
(en)
|
2009-06-25 |
2013-03-19 |
Esbatech, An Alcon Biomedical Research Unit Llc |
Acceptor framework for CDR grafting
|
|
KR101962476B1
(ko)
|
2009-07-03 |
2019-03-26 |
아비펩 피티와이 리미티트 |
면역성 접합체 및 그 제조방법
|
|
EP2275442A1
(en)
|
2009-07-06 |
2011-01-19 |
Ludwig-Maximilians-Universität München |
Detection and vizualization of the cell cycle in living cells
|
|
EP2462161B1
(en)
|
2009-08-06 |
2017-03-08 |
Immunas Pharma, Inc. |
Antibodies that specifically bind to a beta oligomers and use thereof
|
|
EP2287202A1
(en)
|
2009-08-07 |
2011-02-23 |
Dublin City University |
Anti-sialic acid antibody molecules
|
|
JP5934099B2
(ja)
|
2009-10-01 |
2016-06-15 |
アメリカ合衆国 |
抗血管内皮増殖因子受容体−２キメラ抗原受容体及び癌の治療のためのその使用
|
|
EP3778917A3
(en)
|
2009-12-04 |
2021-06-09 |
F. Hoffmann-La Roche AG |
Multispecific antibodies, antibody analogs, compositions, and methods
|
|
EP2524233A4
(en)
|
2010-01-15 |
2013-07-31 |
Univ California |
COMPOSITIONS AND METHOD FOR DETECTING CANCER
|
|
EP2347769A1
(en)
|
2010-01-20 |
2011-07-27 |
Glycotope GmbH |
Cancer stem cell markers and uses thereof
|
|
US8883977B2
(en)
|
2010-04-28 |
2014-11-11 |
Shionogi & Co., Ltd. |
MUC1 antibody
|
|
EP2566890A4
(en)
|
2010-05-03 |
2013-11-20 |
Abbvie Inc |
ANTI-PAI-1 ANTIBODIES AND METHOD FOR THEIR USE
|
|
US20130236486A1
(en)
|
2010-06-11 |
2013-09-12 |
Mayo Foundation For Medical Education And Research |
Immunogenic vaccine
|
|
CA2805222A1
(en)
|
2010-07-13 |
2012-01-19 |
Ultragenyx Pharmaceutical Inc. |
Methods and formulations for treating sialic acid deficiencies
|
|
EP2407487A1
(en)
|
2010-07-14 |
2012-01-18 |
F-Star Biotechnologische Forschungs - und Entwicklungsges. M.B.H. |
Multispecific modular antibody
|
|
US8658774B2
(en)
|
2010-10-08 |
2014-02-25 |
City Of Hope |
Meditopes and related meditope-monoclonal antibody delivery systems, synthesis and therapeutic uses thereof
|
|
US20120115878A1
(en)
|
2010-11-10 |
2012-05-10 |
John Vincent Calienni |
Salt(s) of 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7h-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide and processes of making thereof
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
US20130243744A1
(en)
*
|
2011-01-06 |
2013-09-19 |
Michael J. Betenbaugh |
Method of production of recombinant glycoproteins with increased circulatory half-life in mammalian cells
|
|
CA2863578C
(en)
|
2011-02-01 |
2021-10-26 |
Hibm Research Group, Inc. |
Methods and compositions for increasing sialic acid production and treating sialic related disease conditions
|
|
US20140005069A1
(en)
|
2011-03-01 |
2014-01-02 |
Glycosensors And Diagnostics, Llc. |
Glycoprofiling with multiplexed suspension arrays
|
|
WO2012133572A1
(ja)
|
2011-03-30 |
2012-10-04 |
国立大学法人富山大学 |
形質細胞または形質芽細胞の選択方法、目的抗原特異的な抗体の製造方法、新規モノクローナル抗体
|
|
EP2717916B1
(en)
|
2011-06-10 |
2017-03-08 |
Mersana Therapeutics, Inc. |
Protein-polymer-drug conjugates
|
|
WO2013023251A1
(en)
|
2011-08-18 |
2013-02-21 |
Affinity Biosciences Pty Ltd |
Soluble polypeptides
|
|
WO2013033420A1
(en)
|
2011-08-30 |
2013-03-07 |
Whitehead Institute For Biomedical Research |
Methods of downregulating translocated oncogene expression using bromodomain inhibitors
|
|
EP2756521A4
(en)
|
2011-09-16 |
2015-04-22 |
Univ Pennsylvania |
RNA-MANIPULATED T-CELLS FOR THE TREATMENT OF CANCER
|
|
KR102541217B1
(ko)
|
2011-10-10 |
2023-06-08 |
시티 오브 호프 |
메디토프와 메디토프-결합 항체 및 이들의 용도
|
|
WO2013074916A1
(en)
|
2011-11-18 |
2013-05-23 |
Board Of Regents, The University Of Texas System |
Car+ t cells genetically modified to eliminate expression of t- cell receptor and/or hla
|
|
DK2794658T3
(en)
|
2011-12-19 |
2017-06-19 |
Synimmune Gmbh |
BISPECIFIC ANTIBODY MOLECULE
|
|
US20130177579A1
(en)
|
2012-01-06 |
2013-07-11 |
Bioalliance C.V. |
Anti-transferrin receptor antibodies and methods using same
|
|
AU2013222267A1
(en)
|
2012-02-22 |
2014-07-31 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for generating a persisting population of T cells useful for the treatment of cancer
|
|
US20150266939A1
(en)
|
2012-03-15 |
2015-09-24 |
Permeon Biologics, Inc. |
Cell penetrating compositions for delivery of intracellular antibodies and antibody-like moieties and methods of use
|
|
WO2013151649A1
(en)
*
|
2012-04-04 |
2013-10-10 |
Sialix Inc |
Glycan-interacting compounds
|
|
EP3586874A1
(en)
|
2012-08-14 |
2020-01-01 |
IBC Pharmaceuticals, Inc. |
T-cell redirecting bispecific antibodies for treatment of disease
|
|
EP2888367B1
(en)
|
2012-08-22 |
2020-04-29 |
Mogam Biotechnology Research Institute |
Screening and engineering method of super-stable immunoglobulin variable domains and their uses
|
|
US9937205B2
(en)
|
2012-09-04 |
2018-04-10 |
The Trustees Of The University Of Pennsylvania |
Inhibition of diacylglycerol kinase to augment adoptive T cell transfer
|
|
US9598489B2
(en)
|
2012-10-05 |
2017-03-21 |
The Trustees Of The Univeristy Of Pennsylvania |
Human alpha-folate receptor chimeric antigen receptor
|
|
SG11201503271XA
(en)
|
2012-11-06 |
2015-05-28 |
Scholar Rock Inc |
Compositions and methods for modulating cell signaling
|
|
US10226535B2
(en)
|
2012-12-10 |
2019-03-12 |
Mersana Therapeutics, Inc. |
Auristatin compounds and conjugates thereof
|
|
RU2664463C2
(ru)
*
|
2012-12-24 |
2018-08-17 |
Эббви Инк. |
Белки, связывающие рецептор пролактина, и их применение
|
|
EP2752487A1
(en)
|
2013-01-03 |
2014-07-09 |
Sanofi |
Intracellular phenotypic screening
|
|
US20160022829A1
(en)
|
2013-03-14 |
2016-01-28 |
Mersana Therapeutics, Inc. |
Tubulysin compounds and conjugates thereof
|
|
MX2015012059A
(es)
|
2013-03-15 |
2016-01-12 |
Merck Patent Gmbh |
Anticuerpos biespecificos tetravalentes.
|
|
JP6480907B2
(ja)
|
2013-03-15 |
2019-03-13 |
メモリアル スローン ケタリング キャンサー センター |
多量体化技術
|
|
US9718888B2
(en)
|
2013-07-23 |
2017-08-01 |
Ohio State Innovation Foundation |
Methods and compositions related to single chain antibody fragments that bind to tumor-associated glycoprotein 72 (TAG-72)
|
|
WO2015048748A1
(en)
|
2013-09-30 |
2015-04-02 |
Board Of Regents, The University Of Texas System |
Myeloid-derived suppressor cell-specific peptides for diagnostic and therapeutic use
|
|
US20160264684A1
(en)
|
2013-10-10 |
2016-09-15 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
|
SG11201607038TA
(en)
*
|
2014-03-04 |
2016-09-29 |
Sigma Aldrich Co Llc |
Viral resistant cells and uses thereof
|
|
GB201406767D0
(en)
*
|
2014-04-15 |
2014-05-28 |
Cancer Rec Tech Ltd |
Humanized anti-Tn-MUC1 antibodies anf their conjugates
|
|
PH12016502345B1
(en)
|
2014-05-28 |
2023-03-01 |
Agenus Inc |
Anti-gitr antibodies and methods of use thereof
|
|
TWI695011B
(zh)
|
2014-06-18 |
2020-06-01 |
美商梅爾莎納醫療公司 |
抗ｈｅｒ２表位之單株抗體及其使用之方法
|
|
JP2017526676A
(ja)
|
2014-08-27 |
2017-09-14 |
オンコメッド ファーマシューティカルズ インコーポレイテッド |
がんの処置のための併用療法
|
|
WO2016057916A1
(en)
|
2014-10-10 |
2016-04-14 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
|
WO2016057890A1
(en)
|
2014-10-10 |
2016-04-14 |
Siamab Therapeutics, Inc. |
Glycan analysis and profiling
|
|
PT3218005T
(pt)
|
2014-11-12 |
2023-04-11 |
Seagen Inc |
Compostos que interagem com glicano e métodos de uso
|
|
US9879087B2
(en)
|
2014-11-12 |
2018-01-30 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
US11066480B2
(en)
|
2015-03-17 |
2021-07-20 |
Memorial Sloan Kettering Cancer Center |
Anti-MUC16 antibodies and uses thereof
|
|
EP3091032A1
(en)
|
2015-05-08 |
2016-11-09 |
Miltenyi Biotec GmbH |
Humanized antibody or fragment thereof specific for cd3
|
|
US20200041517A1
(en)
|
2015-06-12 |
2020-02-06 |
Seattle Genetics, Inc. |
Compositions and methods for targeting cancer stem cells
|
|
JP7066613B2
(ja)
|
2015-11-12 |
2022-05-13 |
シージェン インコーポレイテッド |
グリカン相互作用化合物および使用方法
|
|
US20190031780A1
(en)
|
2016-01-27 |
2019-01-31 |
Siamab Therapeutics, Inc. |
Compositions and methods for targeting cancer stem cells
|
|
US11401330B2
(en)
|
2016-11-17 |
2022-08-02 |
Seagen Inc. |
Glycan-interacting compounds and methods of use
|
|
US20200247902A1
(en)
*
|
2016-11-17 |
2020-08-06 |
Seattle Genetics, Inc. |
Compositions and methods for treating cancer
|
|
WO2018160909A1
(en)
*
|
2017-03-03 |
2018-09-07 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|