|
JP6257607B2
(ja)
|
2012-06-08 |
2018-01-10 |
アデュロ バイオテック，インコーポレイテッド |
癌免疫療法のための組成物および方法
|
|
EP2931738B1
(en)
|
2012-12-13 |
2019-02-06 |
Aduro Biotech, Inc. |
Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use
|
|
AU2013363087B2
(en)
|
2012-12-19 |
2018-07-19 |
Board Of Regents, The University Of Texas System |
Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway
|
|
CA2908154C
(en)
|
2013-04-29 |
2023-11-28 |
Memorial Sloan Kettering Cancer Center |
Compositions and methods for altering second messenger signaling
|
|
CN105377867B
(zh)
|
2013-05-03 |
2019-11-12 |
加利福尼亚大学董事会 |
I型干扰素的环状二核苷酸诱导
|
|
CU24377B1
(es)
|
2013-05-18 |
2018-12-05 |
Aduro Biotech Inc |
Dinucléotidos de purina cíclicos y composiciones de los mismos útiles para inducir la producción de interferón de tipo i dependientes de sting
|
|
US9549944B2
(en)
|
2013-05-18 |
2017-01-24 |
Aduro Biotech, Inc. |
Compositions and methods for inhibiting “stimulator of interferon gene”—dependent signalling
|
|
US10176292B2
(en)
|
2013-07-31 |
2019-01-08 |
Memorial Sloan-Kettering Cancer Center |
STING crystals and modulators
|
|
SG11201609021QA
(en)
|
2014-06-04 |
2016-11-29 |
Glaxosmithkline Ip Dev Ltd |
Cyclic di-nucleotides as modulators of sting
|
|
DK3233882T3
(da)
|
2014-12-16 |
2020-01-27 |
Kayla Therapeutics |
Fluorinerede cykliske dinukleotider til cytokininduktion
|
|
WO2016096577A1
(en)
*
|
2014-12-16 |
2016-06-23 |
Invivogen |
Combined use of a chemotherapeutic agent and a cyclic dinucleotide for cancer treatment
|
|
CN107106589A
(zh)
*
|
2014-12-17 |
2017-08-29 |
立博美华基因科技有限责任公司 |
用cGAMP或cGAsMP治疗癌症的方法
|
|
GB201501462D0
(en)
|
2015-01-29 |
2015-03-18 |
Glaxosmithkline Ip Dev Ltd |
Novel compounds
|
|
EA035817B1
(ru)
|
2015-03-10 |
2020-08-14 |
Адуро Байотек, Инк. |
Композиции и способы для активации сигналинга, зависимого от "гена стимулятора интерферона"
|
|
CN106692967A
(zh)
*
|
2015-08-12 |
2017-05-24 |
聊城市奥润生物医药科技有限公司 |
环二核苷酸cGAMP联合PD1的抗体（Nivolumab）在制备抗肿瘤药物中的应用
|
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
JP6596146B2
(ja)
|
2015-08-13 |
2019-10-23 |
メルク・シャープ・アンド・ドーム・コーポレーション |
Ｓｔｉｎｇアゴニストとしての環状ジヌクレオチド化合物
|
|
US9809597B2
(en)
|
2015-08-20 |
2017-11-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Ganciclovir derivatives for modulating innate and adaptive immunity and for use in immunotherapy
|
|
CN106540255A
(zh)
*
|
2015-09-18 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
环二核苷酸cGAMP联合贝伐珠单抗在抗肿瘤中的应用
|
|
WO2017062838A1
(en)
|
2015-10-07 |
2017-04-13 |
Nant Holdings Ip, Llc |
Activation of immune-related signalling pathways in cells via optofection
|
|
CN108430503A
(zh)
|
2015-10-28 |
2018-08-21 |
艾杜罗生物科技公司 |
用于激活“干扰素基因刺激物”依赖性信号传导的组合物和方法
|
|
CN106539812B
(zh)
*
|
2015-11-18 |
2019-12-03 |
杭州星鳌生物科技有限公司 |
环二核苷酸cGAMP在抗结直肠癌肝转移中的应用
|
|
CN106539813B
(zh)
*
|
2015-11-30 |
2019-12-03 |
杭州星鳌生物科技有限公司 |
干扰素刺激基因(sting)激活剂在抗炎症中的应用
|
|
CR20180286A
(es)
|
2015-12-03 |
2018-07-16 |
Glaxosmithkline Ip Dev Ltd |
Dinucleotidos de purina cíclicos como moduladores de sting
|
|
CN106540260A
(zh)
*
|
2015-12-09 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
干扰素基因刺激蛋白（sting）激动剂在抗阿尔兹海默症中的应用
|
|
CN106539814A
(zh)
*
|
2015-12-09 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
干扰素基因刺激蛋白（sting）激动剂在抗类风湿性关节炎等疾病中的应用
|
|
WO2017106740A1
(en)
*
|
2015-12-16 |
2017-06-22 |
Aduro Biotech, Inc. |
Methods for identifying inhibitors of "stimulator of interferon gene"-dependent interferon production
|
|
CN106539811B
(zh)
*
|
2016-01-16 |
2019-12-20 |
杭州星鳌生物科技有限公司 |
环二核苷酸cGAMP在防治抗肿瘤化药诱发的并发症或降低化疗药诱导的毒副作用中的应用
|
|
CN106539815B
(zh)
*
|
2016-01-21 |
2019-12-03 |
杭州星鳌生物科技有限公司 |
环二核苷酸在防治多发性硬化症中的应用
|
|
CN109475570B
(zh)
|
2016-03-18 |
2022-04-01 |
免疫传感器公司 |
环二核苷酸化合物及使用方法
|
|
CN106539757A
(zh)
*
|
2016-03-20 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
环二核苷酸cGAMP-脂质体在抗肿瘤中的应用
|
|
CN106540256A
(zh)
*
|
2016-03-27 |
2017-03-29 |
聊城市奥润生物医药科技有限公司 |
环二核苷酸-脂质体偶联单克隆抗体在抗肿瘤中的应用
|
|
CN105969754A
(zh)
*
|
2016-04-29 |
2016-09-28 |
山东省农业科学院畜牧兽医研究所 |
改造的核苷酸环化酶及其应用
|
|
US10696985B1
(en)
|
2016-06-06 |
2020-06-30 |
Vanderbilt University |
Reversibly crosslinked endosomolytic polymer vesicles for cytosolic drug delivery
|
|
CN106552265A
(zh)
*
|
2016-06-21 |
2017-04-05 |
聊城市奥润生物医药科技有限公司 |
Sting激动剂与ido1抑制剂联合用药在抗肿瘤中的应用
|
|
WO2018009466A1
(en)
|
2016-07-05 |
2018-01-11 |
Aduro Biotech, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
|
AU2017293781B2
(en)
*
|
2016-07-06 |
2022-12-22 |
Invox Pharma Limited |
Compounds, compositions, and methods for the treatment of disease
|
|
WO2018009652A1
(en)
*
|
2016-07-06 |
2018-01-11 |
Sperovie Biosciences, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
|
NL2017270B1
(en)
|
2016-08-02 |
2018-02-09 |
Aduro Biotech Holdings Europe B V |
New anti-hCTLA-4 antibodies
|
|
BR112019004042A2
(pt)
|
2016-08-30 |
2019-05-28 |
Dana-Farber Cancer Institute, Inc. |
composições de liberação de fármaco e usos das mesmas
|
|
EA037513B1
(ru)
*
|
2016-09-17 |
2021-04-06 |
ИММЬЮН СЕНСОР, ЭлЭлСи |
Циклические динуклеотидные соединения и способы их применения
|
|
US10537590B2
(en)
|
2016-09-30 |
2020-01-21 |
Boehringer Ingelheim International Gmbh |
Cyclic dinucleotide compounds
|
|
GEP20217285B
(en)
|
2016-10-04 |
2021-08-10 |
Merck Sharp & Dohme |
BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS
|
|
EP3523314A1
(de)
|
2016-10-07 |
2019-08-14 |
Biolog Life Science Institute Forschungslabor Und Biochemica-Vertrieb GmbH |
Benzimidazolhaltige cyclische dinukleotide, verfahren zu deren herstellung und ihre verwendung zur aktivierung von stimulator von interferongenen (sting)-abhängigen signalwegen
|
|
PE20191353A1
(es)
|
2016-10-14 |
2019-10-01 |
Prec Biosciences Inc |
Meganucleasas disenadas especificamente para el reconocimiento de secuencias en el genoma del virus de la hepatitis b
|
|
JOP20170192A1
(ar)
|
2016-12-01 |
2019-01-30 |
Takeda Pharmaceuticals Co |
داي نوكليوتيد حلقي
|
|
EA201991556A1
(ru)
*
|
2016-12-22 |
2020-01-23 |
Мавуфарма, Инк. |
Ингибиторы фосфодиэстеразы и способы лечения микробной инфекции
|
|
JP2020504745A
(ja)
*
|
2016-12-22 |
2020-02-13 |
マブファーマ，インク． |
Ｉ型ｉｆｎ産生を増強または増大する組成物および方法
|
|
WO2018138685A2
(en)
*
|
2017-01-27 |
2018-08-02 |
Janssen Biotech, Inc. |
Cyclic dinucleotides as sting agonists
|
|
EP3576780A1
(en)
|
2017-02-01 |
2019-12-11 |
Modernatx, Inc. |
Immunomodulatory therapeutic mrna compositions encoding activating oncogene mutation peptides
|
|
US20200055883A1
(en)
|
2017-02-17 |
2020-02-20 |
Eisai R&D Management Co., Ltd. |
Cyclic di-nucleotides derivative for the treatment of cancer
|
|
JP2018131427A
(ja)
*
|
2017-02-17 |
2018-08-23 |
国立研究開発法人理化学研究所 |
免疫細胞の制御技術
|
|
CN106667914B
(zh)
*
|
2017-03-13 |
2022-02-01 |
杭州星鳌生物科技有限公司 |
靶向脂质体-环二核苷酸的组成、制备方法及其在抗肿瘤中的应用
|
|
CN106727331B
(zh)
*
|
2017-03-13 |
2022-02-01 |
杭州星鳌生物科技有限公司 |
免疫脂质体-环二核苷酸的组成、制备方法及其在抗肿瘤中的应用
|
|
EP3601536A4
(en)
|
2017-03-20 |
2021-01-13 |
Genocea Biosciences, Inc. |
TREATMENT PROCESSES
|
|
JOP20190218A1
(ar)
|
2017-03-22 |
2019-09-22 |
Boehringer Ingelheim Int |
مركبات ثنائية النيوكليوتيدات حلقية معدلة
|
|
CN110650976B
(zh)
|
2017-04-13 |
2024-04-19 |
赛罗帕私人有限公司 |
抗SIRPα抗体
|
|
BR112019021520A2
(pt)
|
2017-04-14 |
2020-08-04 |
Tollnine, Inc. |
oligonucleotídeo, composto, polinucleotídeo imunomodulador, composição, conjugado, método para modular um receptor, método de tratamento de um tumor, método de tratamento de câncer, método para tratar um tumor, método de prevenção de câncer, método para induzir uma resposta imune
|
|
US11466047B2
(en)
|
2017-05-12 |
2022-10-11 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
AU2018311966A1
(en)
|
2017-08-04 |
2020-02-13 |
Merck Sharp & Dohme Llc |
Benzo[b]thiophene sting agonists for cancer treatment
|
|
MA49773A
(fr)
|
2017-08-04 |
2021-04-21 |
Merck Sharp & Dohme |
Combinaisons d'antagonistes de pd-1 et d'agonistes de sting benzo[b
|
|
CA3074268A1
(en)
|
2017-09-08 |
2019-03-14 |
The Board Of Trustees Of The Leland Stanford Junior University |
Enpp1 inhibitors and their use for the treatment of cancer
|
|
US11707531B2
(en)
|
2017-09-11 |
2023-07-25 |
F-star Therapeutics, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
|
US11584774B2
(en)
|
2017-09-11 |
2023-02-21 |
F-star Therapeutics, Inc. |
Compounds, compositions, and methods for the treatment of disease
|
|
CN107619438B
(zh)
*
|
2017-10-11 |
2021-12-03 |
广州云启科技有限公司 |
新型环二核苷酸受体及其激动剂或抑制剂筛选的方法和试剂盒
|
|
CN109694397B
(zh)
*
|
2017-10-23 |
2021-08-31 |
上海弘翊生物科技有限公司 |
环状二核苷酸化合物、其制备方法和应用
|
|
PH12020550585A1
(en)
|
2017-11-10 |
2021-04-19 |
Takeda Pharmaceuticals Co |
Sting modulator compounds, and methods of making and using
|
|
JP7098748B2
(ja)
|
2017-12-20 |
2022-07-11 |
インスティチュート オブ オーガニック ケミストリー アンド バイオケミストリー エーエスシーアール，ヴイ．ヴイ．アイ． |
Ｓｔｉｎｇアダプタータンパク質を活性化するホスホン酸結合を有する２’３’環状ジヌクレオチド
|
|
US11685761B2
(en)
|
2017-12-20 |
2023-06-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
|
AU2018392213B2
(en)
|
2017-12-20 |
2021-03-04 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3' cyclic dinucleotides with phosphonate bond activating the STING adaptor protein
|
|
WO2019147509A1
(en)
*
|
2018-01-26 |
2019-08-01 |
The Regents Of The University Of California |
Intranasal delivery of a cyclic-di-nucleotide adjuvanted vaccine for tuberculosis
|
|
WO2019161171A1
(en)
*
|
2018-02-16 |
2019-08-22 |
Sperovie Biosciences, Inc. |
Nanoparticle formulations of sting agonists
|
|
AU2019223182B2
(en)
|
2018-02-26 |
2021-08-19 |
Gilead Sciences, Inc. |
Substituted pyrrolizine compounds as HBV replication inhibitors
|
|
WO2019183578A1
(en)
|
2018-03-23 |
2019-09-26 |
Codiak Biosciences, Inc. |
Extracellular vesicles comprising sting-agonist
|
|
US20210017541A1
(en)
*
|
2018-03-26 |
2021-01-21 |
University Of Miami |
Recombinant viral vector and uses thereof
|
|
EP3774833A1
(en)
|
2018-03-27 |
2021-02-17 |
Boehringer Ingelheim International GmbH |
Modified cyclic dinucleotide compounds
|
|
EP3774834A1
(en)
|
2018-03-27 |
2021-02-17 |
Boehringer Ingelheim International GmbH |
Cyclic dinucleotide compounds containing 2-aza-hypoxanthine or 6h-pytazolo[1,5-d][1,2,4]triazin-7-one as sting agonists
|
|
EP3774765A4
(en)
|
2018-04-03 |
2021-12-29 |
Merck Sharp & Dohme Corp. |
Aza-benzothiophene compounds as sting agonists
|
|
MX2020010407A
(es)
|
2018-04-03 |
2020-10-22 |
Merck Sharp & Dohme |
Benzotiofenos y compuestos relacionados como agonistas de sting.
|
|
WO2019195658A1
(en)
|
2018-04-05 |
2019-10-10 |
Dana-Farber Cancer Institute, Inc. |
Sting levels as a biomarker for cancer immunotherapy
|
|
US10870691B2
(en)
|
2018-04-05 |
2020-12-22 |
Gilead Sciences, Inc. |
Antibodies and fragments thereof that bind hepatitis B virus protein X
|
|
TW202005654A
(zh)
|
2018-04-06 |
2020-02-01 |
捷克科學院有機化學與生物化學研究所 |
２，２，─環二核苷酸
|
|
TWI818007B
(zh)
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
|
TWI833744B
(zh)
|
2018-04-06 |
2024-03-01 |
捷克科學院有機化學與生物化學研究所 |
3'3'-環二核苷酸
|
|
US11142750B2
(en)
|
2018-04-12 |
2021-10-12 |
Precision Biosciences, Inc. |
Optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome
|
|
CN108310378A
(zh)
*
|
2018-04-28 |
2018-07-24 |
杭州星鳌生物科技有限公司 |
一类新型免疫联体抗肿瘤创新药物的制备及其应用
|
|
US20190359645A1
(en)
|
2018-05-03 |
2019-11-28 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3'-cyclic dinucleotides comprising carbocyclic nucleotide
|
|
US20210275547A1
(en)
*
|
2018-05-17 |
2021-09-09 |
The Regents Of The University Of California |
Methods of Modulating Activity of a Cyclic Dinucleotide (CDN) with a CDN Transporter-Modulating Agent
|
|
JP7335277B2
(ja)
|
2018-06-01 |
2023-08-29 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
膀胱がんの治療のための方法
|
|
WO2020006038A1
(en)
*
|
2018-06-29 |
2020-01-02 |
Dana-Farber Cancer Institute, Inc. |
Structure of the human cgas-dna complex and uses thereof
|
|
EP3820477A4
(en)
|
2018-07-10 |
2022-07-13 |
Sperovie Biosciences, Inc. |
COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES
|
|
WO2020028097A1
(en)
|
2018-08-01 |
2020-02-06 |
Gilead Sciences, Inc. |
Solid forms of (r)-11-(methoxymethyl)-12-(3-methoxypropoxy)-3,3-dimethyl-8-0x0-2,3,8,13b-tetrahydro-1h-pyrido[2,1-a]pyrrolo[1,2-c] phthalazine-7-c arboxylic acid
|
|
ES3021247T3
(en)
|
2018-08-16 |
2025-05-26 |
Eisai R&D Man Co Ltd |
Salts of compounds and crystals thereof
|
|
CA3113425A1
(en)
|
2018-09-21 |
2020-03-26 |
Shanghai De Novo Pharmatech Co., Ltd. |
Cyclic dinucleotide analogue, pharmaceutical composition thereof, and application
|
|
AU2019373241A1
(en)
|
2018-10-29 |
2021-06-10 |
Genocea Biosciences, Inc. |
Treatment methods
|
|
WO2020092633A1
(en)
|
2018-10-30 |
2020-05-07 |
Vanderbilt University |
Graft copolymers, methods of forming graft copolymers, and methods of use thereof
|
|
TWI721624B
(zh)
|
2018-10-31 |
2021-03-11 |
美商基利科學股份有限公司 |
經取代之6-氮雜苯并咪唑化合物
|
|
ES2979163T3
(es)
|
2018-10-31 |
2024-09-24 |
Gilead Sciences Inc |
Compuestos de 6-azabenzimidazol sustituidos como inhibidores de HPK1
|
|
JP7251838B2
(ja)
*
|
2019-03-01 |
2023-04-04 |
ヤマサ醤油株式会社 |
３’，３’－ｃＧＡＭＰの実践的酵素合成法
|
|
AU2020231201B2
(en)
|
2019-03-07 |
2025-02-20 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3'-cyclic dinucleotides and prodrugs thereof
|
|
AU2020231115B2
(en)
|
2019-03-07 |
2025-02-20 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3'-cyclic dinucleotides and prodrugs thereof
|
|
WO2020178768A1
(en)
|
2019-03-07 |
2020-09-10 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3'3'-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator
|
|
US12502427B2
(en)
|
2019-03-21 |
2025-12-23 |
Lonza Sales Ag |
Extracellular vesicles for vaccine delivery
|
|
AU2020241903A1
(en)
|
2019-03-21 |
2021-10-14 |
Lonza Sales Ag |
Extracellular vesicle conjugates and uses thereof
|
|
TWI751517B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TW202210480A
(zh)
|
2019-04-17 |
2022-03-16 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
CA3137119A1
(en)
|
2019-05-09 |
2020-11-12 |
Aligos Therapeutics, Inc. |
Modified cyclic dinucleoside compounds as sting modulators
|
|
US11453681B2
(en)
|
2019-05-23 |
2022-09-27 |
Gilead Sciences, Inc. |
Substituted eneoxindoles and uses thereof
|
|
UA129329C2
(uk)
|
2019-06-25 |
2025-03-19 |
Гіліад Сайєнсіз, Інк. |
ЗЛИТІ БІЛКИ FLT3L-Fc
|
|
EP3994158A1
(en)
|
2019-07-03 |
2022-05-11 |
Codiak BioSciences, Inc. |
Extracellular vesicles targeting t cells and uses thereof
|
|
US20230181758A1
(en)
|
2019-07-03 |
2023-06-15 |
Codiak Biosciences, Inc. |
Extracellular vesicles targeting dendritic cells and uses thereof
|
|
EP4017476A1
(en)
|
2019-08-19 |
2022-06-29 |
Gilead Sciences, Inc. |
Pharmaceutical formulations of tenofovir alafenamide
|
|
WO2021041532A1
(en)
|
2019-08-26 |
2021-03-04 |
Dana-Farber Cancer Institute, Inc. |
Use of heparin to promote type 1 interferon signaling
|
|
EP3785719A1
(en)
*
|
2019-08-28 |
2021-03-03 |
Helmholtz-Zentrum für Infektionsforschung GmbH |
New use of cyclic dinucleotides
|
|
EP4034247A1
(en)
|
2019-09-25 |
2022-08-03 |
Codiak BioSciences, Inc. |
Sting agonist comprising exosomes for treating neuroimmunological disorders
|
|
JP2022549328A
(ja)
|
2019-09-25 |
2022-11-24 |
コディアック バイオサイエンシーズ， インコーポレイテッド |
細胞外小胞組成物
|
|
EP4034150A1
(en)
|
2019-09-25 |
2022-08-03 |
Codiak BioSciences, Inc. |
Sting agonist comprising exosomes combined with il-12 displaying exosomes for treating a tumour
|
|
EP4034276A1
(en)
|
2019-09-25 |
2022-08-03 |
Codiak BioSciences, Inc. |
Methods of producing extracellular vesicles
|
|
MX2022003658A
(es)
|
2019-09-30 |
2022-04-25 |
Gilead Sciences Inc |
Vacunas contra el virus de la hepatitis b (vhb) y metodos para tratar el vhb.
|
|
AU2020362115A1
(en)
*
|
2019-10-07 |
2022-04-21 |
The General Hospital Corporation |
Compositions and methods for pulmonary surfactant-biomimetic nanoparticles
|
|
DK4069729T3
(da)
|
2019-12-06 |
2025-04-07 |
Prec Biosciences Inc |
Optimerede, modificerede meganukleaser med specificitet for en genkendelsessekvens i hepatitis b-virusgenomet
|
|
MX2022010515A
(es)
|
2020-02-28 |
2022-11-14 |
Tallac Therapeutics Inc |
Conjugacion mediada por transglutaminasa.
|
|
WO2021184017A1
(en)
|
2020-03-13 |
2021-09-16 |
Codiak Biosciences, Inc. |
Extracellular vesicles for treating neurological disorders
|
|
AU2021237718B2
(en)
|
2020-03-20 |
2023-09-21 |
Gilead Sciences, Inc. |
Prodrugs of 4'-C-substituted-2-halo-2'-deoxyadenosine nucleosides and methods of making and using the same
|
|
JP2023518414A
(ja)
|
2020-03-20 |
2023-05-01 |
コディアック バイオサイエンシーズ， インコーポレイテッド |
治療のための細胞外小胞
|
|
WO2021237100A1
(en)
|
2020-05-21 |
2021-11-25 |
Codiak Biosciences, Inc. |
Methods of targeting extracellular vesicles to lung
|
|
CN116194144A
(zh)
|
2020-08-07 |
2023-05-30 |
吉利德科学公司 |
膦酰胺核苷酸类似物的前药及其药物用途
|
|
CA3191593A1
(en)
|
2020-09-08 |
2022-03-17 |
Jinming Gao |
Polyvalent sting activating compositions and uses thereof
|
|
WO2022066883A1
(en)
|
2020-09-23 |
2022-03-31 |
Codiak Biosciences, Inc. |
Extracellular vesicles comprising kras antigens and uses thereof
|
|
EP4216993A2
(en)
|
2020-09-23 |
2023-08-02 |
Codiak BioSciences, Inc. |
Methods of producing extracellular vesicles
|
|
AU2021374958A1
(en)
|
2020-11-09 |
2023-06-22 |
Takeda Pharmaceutical Company Limited |
Antibody drug conjugates
|
|
WO2022174065A1
(en)
*
|
2021-02-12 |
2022-08-18 |
The Regents Of The University Of California |
Methods for inducing an interferon response by regulating morc3
|
|
AU2022274607A1
(en)
|
2021-05-13 |
2023-11-16 |
Gilead Sciences, Inc. |
COMBINATION OF A TLR8 MODULATING COMPOUND AND ANTI-HBV siRNA THERAPEUTICS
|
|
US20220389394A1
(en)
|
2021-05-18 |
2022-12-08 |
Gilead Sciences, Inc. |
METHODS OF USING FLT3L-Fc FUSION PROTEINS
|
|
US12208150B2
(en)
*
|
2021-05-20 |
2025-01-28 |
Shielded, Beauty, LLC |
Antimicrobial skincare composition
|
|
CN113265435A
(zh)
*
|
2021-06-16 |
2021-08-17 |
中国农业科学院兰州兽医研究所 |
一种细菌第二信使分子环二核苷酸的制备方法
|
|
CN117396478A
(zh)
|
2021-06-23 |
2024-01-12 |
吉利德科学公司 |
二酰基甘油激酶调节化合物
|
|
KR20240023629A
(ko)
|
2021-06-23 |
2024-02-22 |
길리애드 사이언시즈, 인코포레이티드 |
디아실글리세롤 키나제 조절 화합물
|
|
KR20240023628A
(ko)
|
2021-06-23 |
2024-02-22 |
길리애드 사이언시즈, 인코포레이티드 |
디아실글리세롤 키나제 조절 화합물
|
|
US11932634B2
(en)
|
2021-06-23 |
2024-03-19 |
Gilead Sciences, Inc. |
Diacylglycerol kinase modulating compounds
|
|
WO2023056468A1
(en)
|
2021-09-30 |
2023-04-06 |
Codiak Biosciences, Inc. |
Extracellular vesicle comprising cholesterol tagged sting-agonist
|
|
EP4569129A1
(en)
*
|
2022-08-10 |
2025-06-18 |
Aldevron, LLC |
Methods for producing cyclic dinucleotides
|
|
US20250345390A1
(en)
|
2024-05-13 |
2025-11-13 |
Gilead Sciences, Inc. |
Combination therapies
|
|
WO2025240243A1
(en)
|
2024-05-13 |
2025-11-20 |
Gilead Sciences, Inc. |
Combination therapies with bulevirtide and an inhibitory nucleic acid targeting hepatitis b virus
|
|
WO2025240242A1
(en)
|
2024-05-13 |
2025-11-20 |
Gilead Sciences, Inc. |
Combination therapies with ribavirin
|
|
WO2025240246A1
(en)
|
2024-05-13 |
2025-11-20 |
Gilead Sciences, Inc. |
Combination therapies with ribavirin
|