JP2019043957A5 - - Google Patents
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- Publication number
- JP2019043957A5 JP2019043957A5 JP2018210606A JP2018210606A JP2019043957A5 JP 2019043957 A5 JP2019043957 A5 JP 2019043957A5 JP 2018210606 A JP2018210606 A JP 2018210606A JP 2018210606 A JP2018210606 A JP 2018210606A JP 2019043957 A5 JP2019043957 A5 JP 2019043957A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- group
- compound
- independently
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 0 CC(C)(CC1)[C@](*)C1(C)SC1(CC2)CC2(CC(*)O)CC1 Chemical compound CC(C)(CC1)[C@](*)C1(C)SC1(CC2)CC2(CC(*)O)CC1 0.000 description 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1315335.8 | 2013-08-29 | ||
| GBGB1315335.8A GB201315335D0 (en) | 2013-08-29 | 2013-08-29 | Amino diacids containing peptide modifiers |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016537416A Division JP2016532705A (ja) | 2013-08-29 | 2014-08-28 | アミノ二酸含有ペプチド修飾剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019043957A JP2019043957A (ja) | 2019-03-22 |
| JP2019043957A5 true JP2019043957A5 (enExample) | 2019-05-09 |
| JP6767459B2 JP6767459B2 (ja) | 2020-10-14 |
Family
ID=49356024
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016537416A Pending JP2016532705A (ja) | 2013-08-29 | 2014-08-28 | アミノ二酸含有ペプチド修飾剤 |
| JP2018210606A Active JP6767459B2 (ja) | 2013-08-29 | 2018-11-08 | アミノ二酸含有ペプチド修飾剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016537416A Pending JP2016532705A (ja) | 2013-08-29 | 2014-08-28 | アミノ二酸含有ペプチド修飾剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20160207957A1 (enExample) |
| EP (2) | EP3725801A3 (enExample) |
| JP (2) | JP2016532705A (enExample) |
| KR (1) | KR102461744B1 (enExample) |
| CN (2) | CN110003055B (enExample) |
| AU (2) | AU2014313779B2 (enExample) |
| CA (1) | CA2922220C (enExample) |
| ES (1) | ES2831974T3 (enExample) |
| GB (1) | GB201315335D0 (enExample) |
| WO (1) | WO2015028966A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201315335D0 (en) * | 2013-08-29 | 2013-10-09 | Of Singapore | Amino diacids containing peptide modifiers |
| JP6991196B2 (ja) * | 2016-03-23 | 2022-02-03 | バッヘン・ホールディング・アクチエンゲゼルシャフト | グルカゴン様ペプチドを製造するための方法 |
| US11338018B2 (en) | 2016-12-19 | 2022-05-24 | Harrow Ip, Llc | Adrenocorticotropic hormone-based pharmaceutical formulations and methods for fabricating and using thereof |
| CN110294800B (zh) * | 2018-03-22 | 2022-03-04 | 齐鲁制药有限公司 | 一种索玛鲁肽的制备方法 |
| ES3038393T3 (en) * | 2018-08-09 | 2025-10-13 | Hoffmann La Roche | Cleavable linker for peptide synthesis |
| ES2938734T3 (es) | 2018-10-09 | 2023-04-14 | Fresenius Kabi Ipsum S R L | Procedimiento para la fabricación de análogos de GLP-1 |
| GB201816639D0 (en) * | 2018-10-12 | 2018-11-28 | Heptares Therapeutics Ltd | GLP-1 Receptor Antagonist |
| WO2020150262A1 (en) * | 2019-01-17 | 2020-07-23 | Harrow Ip, Llc | Adrenocorticotropic hormone-based pharmaceutical formulations and methods for fabricating and using thereof |
| CN109776323B (zh) * | 2019-01-28 | 2022-05-17 | 富乐马鸿凯（大连）医药有限公司 | 一种高效选择性制备脂肪二酸单叔丁酯的方法 |
| WO2020208409A1 (en) * | 2019-04-10 | 2020-10-15 | Dr. Reddy’S Laboratories Limited | Improved processes for the preparation of peptide intermediates/modifiers |
| CN110372785B (zh) * | 2019-07-25 | 2020-10-23 | 成都诺和晟泰生物科技有限公司 | 一种索马鲁肽的合成方法 |
| CN111285780A (zh) * | 2020-01-16 | 2020-06-16 | 浙江工业大学 | 索马鲁肽侧链的汇聚式液相合成法 |
| CN111269137A (zh) * | 2020-01-16 | 2020-06-12 | 浙江工业大学 | 一种液相法制备索马鲁肽侧链的方法 |
| CN111253287A (zh) * | 2020-01-16 | 2020-06-09 | 浙江工业大学 | 液相汇聚式合成索马鲁肽侧链的方法 |
| WO2021175974A1 (en) | 2020-03-06 | 2021-09-10 | Sanofi | Peptides as selective gip receptor agonists |
| US12679878B2 (en) | 2020-08-19 | 2026-07-14 | Sanofi | CRF2 receptor agonists and their use in therapy |
| WO2023031455A1 (en) | 2021-09-06 | 2023-03-09 | Sanofi Sa | New peptides as potent and selective gip receptor agonists |
| CN115504893B (zh) * | 2022-11-18 | 2023-03-10 | 成都普康生物科技有限公司 | 一种L-谷氨酸-α-叔丁酯的合成方法 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE122009000079I2 (de) | 1996-08-30 | 2011-06-16 | Novo Nordisk As Novo Alle | Glp-1 derivate |
| NZ507083A (en) | 1998-03-23 | 2003-10-31 | Trimeris Inc | Methods and compositions for peptide synthesis, in particular T-20 (DP-178) and T-20-like peptides |
| US6716963B1 (en) * | 1998-05-22 | 2004-04-06 | Abbott Laboratories | Peptide antiangiogenic drugs |
| GB9812675D0 (en) | 1998-06-11 | 1998-08-12 | Univ Edinburgh | Peptides |
| DE19924606A1 (de) * | 1999-05-28 | 2000-11-30 | Graffinity Pharm Design Gmbh | Ligand-Anker-Konjugate |
| EP1076066A1 (en) | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptides for lowering blood glucose levels |
| WO2001036003A2 (en) * | 1999-11-15 | 2001-05-25 | Drug Innovation & Design, Inc. | Selective cellular targeting: multifunctional delivery vehicles |
| US6621548B2 (en) | 2001-06-15 | 2003-09-16 | Viztec, Inc. | Electrooptical displays constructed with polymer-coated elements positioned between substrates |
| US7671054B1 (en) * | 2001-10-12 | 2010-03-02 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| IL161446A0 (en) * | 2001-11-26 | 2004-09-27 | Daiichi Suntory Pharma Co Ltd | Medicinal compositions for nasal absorption |
| DE60309019T2 (de) | 2002-05-03 | 2007-05-16 | Avecia Ltd., Blackley | Verfahren zur herstellung von peptidamiden durch seitenkettenanknüpfung an einer festphase |
| ES2387803T3 (es) | 2003-01-08 | 2012-10-02 | Novartis Vaccines And Diagnostics, Inc. | Agentes antibacterianos |
| US20040142379A1 (en) * | 2003-01-16 | 2004-07-22 | Carlsberg Research Laboratory | Affinity fishing for ligands and proteins receptors |
| AU2004261353B2 (en) | 2003-08-05 | 2009-12-10 | Novo Nordisk A/S | Novel insulin derivatives |
| ES2369895T3 (es) | 2003-12-03 | 2011-12-07 | Novo Nordisk A/S | Insulina monocatenaria. |
| EP3075247B1 (en) * | 2004-02-02 | 2022-10-12 | BioSight Ltd. | Conjugates for cancer therapy and diagnosis |
| WO2005082404A2 (en) * | 2004-02-27 | 2005-09-09 | Novo Nordisk A/S | Glp-2 derivatives modified by lipophilic substituents |
| JP2008515856A (ja) | 2004-10-07 | 2008-05-15 | ノボ ノルディスク アクティーゼルスカブ | 遅延性ｇｌｐ−１化合物 |
| TWI362392B (en) | 2005-03-18 | 2012-04-21 | Novo Nordisk As | Acylated glp-1 compounds |
| US7560588B2 (en) * | 2006-04-27 | 2009-07-14 | Intezyne Technologies, Inc. | Poly(ethylene glycol) containing chemically disparate endgroups |
| JP2010505781A (ja) | 2006-10-05 | 2010-02-25 | ロンザ ア−ゲ− | ペプチド合成法 |
| KR101046846B1 (ko) | 2006-10-12 | 2011-07-06 | 동국제약 주식회사 | 고체상 합성법을 이용한 펩타이드의 제조방법 |
| WO2009022006A1 (en) | 2007-08-15 | 2009-02-19 | Novo Nordisk A/S | Insulins with an acyl moiety comprising repeating units of alkylene glycol containing amino acids |
| FR2921831B1 (fr) * | 2007-10-05 | 2014-05-09 | Oreal | Composition cosmetique ou dermatologique comprenant un polymere portant des groupes de jonction, et procede de traitement cosmetique |
| EP3673922A1 (en) * | 2008-03-14 | 2020-07-01 | VisEn Medical, Inc. | Integrin targeting agents and methods of using same |
| HUE032284T2 (en) * | 2008-03-18 | 2017-09-28 | Novo Nordisk As | Protease-stabilized, acylated insulin analogues |
| CN102149411A (zh) | 2008-09-12 | 2011-08-10 | 诺沃—诺迪斯克有限公司 | 酰化肽或蛋白的方法 |
| BRPI0921230A2 (pt) * | 2008-11-05 | 2018-10-30 | Hoffmann La Roche | agonistas de receptor de neuropeptídeos-2 (y-2r) e usos dos mesmo. |
| MA32970B1 (fr) * | 2008-12-15 | 2012-01-02 | Zealand Pharma As | Analogues du glucagon |
| CA2756397A1 (en) | 2009-04-02 | 2010-10-07 | Shire Llc | Novel dicarboxylic acid linked amino acid and peptide prodrugs of opioids and uses thereof |
| JP6054742B2 (ja) | 2009-07-13 | 2016-12-27 | ジーランド ファーマ アクティーゼルスカブ | アシル化グルカゴン類似体 |
| JP2013507414A (ja) | 2009-10-13 | 2013-03-04 | エフ．ホフマン−ラ ロシュ アーゲー | 神経ペプチド−２受容体（ｙ−２ｒ）アゴニスト |
| WO2011075393A2 (en) | 2009-12-18 | 2011-06-23 | Indiana University Research And Technology Corporation | Glucagon/glp-1 receptor co-agonists |
| PL2525834T3 (pl) | 2010-01-22 | 2020-10-19 | Novo Nordisk Health Care Ag | Hormony wzrostu o przedłużonej skuteczności in-vivo |
| KR20130018410A (ko) | 2010-03-26 | 2013-02-21 | 노보 노르디스크 에이/에스 | 새로운 글루카곤 유사체 |
| CA2802897A1 (en) | 2010-06-24 | 2011-12-29 | Zealand Pharma A/S | Glucagon analogues |
| CN103097545B (zh) * | 2010-07-07 | 2015-07-22 | 康奈尔大学 | Sirt5调节剂及其筛选方法 |
| JP2013209295A (ja) * | 2010-10-13 | 2013-10-10 | Takeda Chem Ind Ltd | ペプチド誘導体 |
| RU2013117288A (ru) * | 2010-12-17 | 2015-01-27 | Эрроухэд Рисерч Корпорейшн | СОДЕРЖАЩАЯ ГАЛАКТОЗНЫЙ КЛАСТЕР НАЦЕЛИВАЮЩАЯ ГРУППА ДЛЯ миРНК, МОДУЛИРУЮЩАЯ ФОРМАКОКИНЕТИЧЕСКИЕ СВОЙСТВА |
| CN105713957B (zh) * | 2010-12-22 | 2021-03-02 | 康奈尔大学 | Sirt6的调节物及其筛选分析 |
| CN102286092B (zh) | 2011-09-14 | 2014-01-01 | 深圳翰宇药业股份有限公司 | 利拉鲁肽的固相合成方法 |
| CN104011070A (zh) | 2011-12-15 | 2014-08-27 | 爱德迪安（北京）生物技术有限公司 | 具有降血糖作用的化合物、组合物及其用途 |
| KR20140114845A (ko) * | 2011-12-23 | 2014-09-29 | 질랜드 파마 에이/에스 | 글루카곤 유사체 |
| CN102584944B (zh) | 2012-02-06 | 2014-12-17 | 成都圣诺生物科技股份有限公司 | 一种依非巴特的制备方法 |
| EP2664374A1 (en) * | 2012-05-15 | 2013-11-20 | F. Hoffmann-La Roche AG | Lysin-glutamic acid dipeptide derivatives |
| CN102875665B (zh) * | 2012-09-28 | 2014-11-26 | 深圳翰宇药业股份有限公司 | 一种合成利拉鲁肽的方法 |
| CN103214568B (zh) * | 2013-03-08 | 2014-09-24 | 深圳翰宇药业股份有限公司 | 一种固相制备促胰液素的方法 |
| CN103242200A (zh) * | 2013-04-10 | 2013-08-14 | 吉尔生化（上海）有限公司 | 一种Nα-芴甲氧羰基-Nε-乙酰基-赖氨酸的制备方法 |
| GB201315335D0 (en) * | 2013-08-29 | 2013-10-09 | Of Singapore | Amino diacids containing peptide modifiers |
-
2013
- 2013-08-29 GB GBGB1315335.8A patent/GB201315335D0/en not_active Ceased
-
2014
- 2014-08-28 KR KR1020167007531A patent/KR102461744B1/ko active Active
- 2014-08-28 CA CA2922220A patent/CA2922220C/en active Active
- 2014-08-28 ES ES14792591T patent/ES2831974T3/es active Active
- 2014-08-28 JP JP2016537416A patent/JP2016532705A/ja active Pending
- 2014-08-28 AU AU2014313779A patent/AU2014313779B2/en active Active
- 2014-08-28 EP EP20167381.1A patent/EP3725801A3/en not_active Withdrawn
- 2014-08-28 US US14/914,374 patent/US20160207957A1/en not_active Abandoned
- 2014-08-28 EP EP14792591.1A patent/EP3038658B1/en active Active
- 2014-08-28 CN CN201811562748.5A patent/CN110003055B/zh active Active
- 2014-08-28 CN CN201480059789.6A patent/CN105683156A/zh active Pending
- 2014-08-28 WO PCT/IB2014/064123 patent/WO2015028966A2/en not_active Ceased
-
2018
- 2018-11-08 JP JP2018210606A patent/JP6767459B2/ja active Active
- 2018-11-19 US US16/195,145 patent/US11634455B2/en active Active
-
2020
- 2020-06-30 AU AU2020204382A patent/AU2020204382B2/en active Active
-
2023
- 2023-03-23 US US18/189,057 patent/US12441760B2/en active Active
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