JP2018530595A5 - - Google Patents

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Publication number
JP2018530595A5
JP2018530595A5 JP2018519749A JP2018519749A JP2018530595A5 JP 2018530595 A5 JP2018530595 A5 JP 2018530595A5 JP 2018519749 A JP2018519749 A JP 2018519749A JP 2018519749 A JP2018519749 A JP 2018519749A JP 2018530595 A5 JP2018530595 A5 JP 2018530595A5
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JP
Japan
Prior art keywords
trifluoromethyl
ethyl
imidazo
pyrazole
dihydro
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JP2018519749A
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English (en)
Japanese (ja)
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JP6860559B2 (ja
JP2018530595A (ja
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Priority claimed from PCT/US2016/057135 external-priority patent/WO2017066633A1/en
Publication of JP2018530595A publication Critical patent/JP2018530595A/ja
Publication of JP2018530595A5 publication Critical patent/JP2018530595A5/ja
Priority to JP2021053182A priority Critical patent/JP7090770B2/ja
Application granted granted Critical
Publication of JP6860559B2 publication Critical patent/JP6860559B2/ja
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JP2018519749A 2015-10-16 2016-10-14 Ep4アンタゴニスト Active JP6860559B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021053182A JP7090770B2 (ja) 2015-10-16 2021-03-26 Ep4アンタゴニスト

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562242734P 2015-10-16 2015-10-16
US201562242748P 2015-10-16 2015-10-16
US62/242,748 2015-10-16
US62/242,734 2015-10-16
BD2522016 2016-10-13
BD252/2016 2016-10-13
PCT/US2016/057135 WO2017066633A1 (en) 2015-10-16 2016-10-14 Ep4 antagonists

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021053182A Division JP7090770B2 (ja) 2015-10-16 2021-03-26 Ep4アンタゴニスト

Publications (3)

Publication Number Publication Date
JP2018530595A JP2018530595A (ja) 2018-10-18
JP2018530595A5 true JP2018530595A5 (https=) 2019-11-28
JP6860559B2 JP6860559B2 (ja) 2021-04-14

Family

ID=58518017

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018519749A Active JP6860559B2 (ja) 2015-10-16 2016-10-14 Ep4アンタゴニスト
JP2021053182A Active JP7090770B2 (ja) 2015-10-16 2021-03-26 Ep4アンタゴニスト

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021053182A Active JP7090770B2 (ja) 2015-10-16 2021-03-26 Ep4アンタゴニスト

Country Status (11)

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US (3) US10316040B2 (https=)
EP (1) EP3362454B1 (https=)
JP (2) JP6860559B2 (https=)
KR (1) KR102684436B1 (https=)
CN (1) CN108473497B (https=)
AU (1) AU2016338679B2 (https=)
BR (1) BR112018007664B1 (https=)
CA (1) CA3002144C (https=)
IL (1) IL258737A (https=)
MX (1) MX390051B (https=)
WO (1) WO2017066633A1 (https=)

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EA201992676A1 (ru) 2017-05-18 2020-05-06 Идорсия Фармасьютиклз Лтд Фенильные производные в качестве модуляторов pge2 рецепторов
CN110621671A (zh) 2017-05-18 2019-12-27 爱杜西亚药品有限公司 作为pge2受体调节剂的苯并呋喃及苯并噻吩衍生物
CN110621667A (zh) 2017-05-18 2019-12-27 爱杜西亚药品有限公司 嘧啶衍生物
EP3625224B1 (en) 2017-05-18 2021-08-04 Idorsia Pharmaceuticals Ltd N-substituted indole derivatives
PL3625228T3 (pl) 2017-05-18 2021-12-20 Idorsia Pharmaceuticals Ltd Pochodne pirymidyny jako modulatory receptora pge2
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EP3889134B1 (en) 2019-01-22 2024-09-25 Keythera (Suzhou) Pharmaceuticals Co. Ltd. Compound for inhibiting pge2/ep4 signaling transduction inhibiting, preparation method therefor, and medical uses thereof
US20230390303A1 (en) 2020-11-13 2023-12-07 Ono Pharmaceutical Co., Ltd. Cancer treatment by combination of ep4 antagonist and immune checkpoint inhibitor

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