JP2018520352A - アルギナーゼ活性を阻害するための組成物および方法 - Google Patents

アルギナーゼ活性を阻害するための組成物および方法 Download PDF

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JP2018520352A
JP2018520352A JP2017567207A JP2017567207A JP2018520352A JP 2018520352 A JP2018520352 A JP 2018520352A JP 2017567207 A JP2017567207 A JP 2017567207A JP 2017567207 A JP2017567207 A JP 2017567207A JP 2018520352 A JP2018520352 A JP 2018520352A
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JP2018520352A5 (enExample
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グロス，マシュー・アイ
ステッゲルダ，スザンネ・エム
リー，ウェイチュイン
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カリセラ バイオサイエンシズ，インコーポレイテッド
カリセラ バイオサイエンシズ，インコーポレイテッド
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    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A—HUMAN NECESSITIES
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
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    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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    • G01—MEASURING; TESTING
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    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Bioinformatics & Computational Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2017567207A 2015-06-23 2016-06-23 アルギナーゼ活性を阻害するための組成物および方法 Ceased JP2018520352A (ja)

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US201562183524P 2015-06-23 2015-06-23
US62/183,524 2015-06-23
PCT/US2016/038983 WO2016210106A1 (en) 2015-06-23 2016-06-23 Compositions and methods for inhibiting arginase activity

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CN (1) CN107921051A (enExample)
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CA (1) CA2990192A1 (enExample)
EA (1) EA201890113A1 (enExample)
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JP2021535111A (ja) * 2018-08-22 2021-12-16 アストラゼネカ・アクチエボラーグAstrazeneca Aktiebolag アルギナーゼインヒビタ及びその使用方法
JP2022507474A (ja) * 2018-11-16 2022-01-18 アーカス バイオサイエンシーズ インコーポレイテッド Ａｒｇ１及び／又はａｒｇ２の阻害剤
KR20220038105A (ko) * 2019-07-23 2022-03-25 아스트라제네카 아베 아르기나제 저해제 및 이의 사용 방법

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UA123700C2 (uk) 2015-06-23 2021-05-19 Калітера Байосайєнсиз, Інк. Композиції і способи інгібування активності аргінази
HRP20201046T1 (hr) * 2015-10-30 2020-10-16 Calithera Biosciences, Inc. Sastavi i metode za inhibitivnu aktivnost arginase
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KR20190104521A (ko) 2016-11-08 2019-09-10 칼리테라 바이오사이언시즈, 인코포레이티드 아르기나제 억제제 병용 요법들
PE20191541A1 (es) 2016-12-22 2019-10-23 Calithera Biosciences Inc Composiciones y metodos para inhibir la accion de la arginasa
CN108794517B (zh) * 2017-04-27 2021-03-30 南京谷睿生物科技有限公司 一种精氨酸酶抑制剂及其制备方法与用途
BR112019023582A2 (pt) 2017-05-12 2020-06-02 Calithera Biosciences Inc. Método de preparar (3r,4s)-3-acetamido-4-alil-n-(terc-butil)pirrolidina-3-carboxamida
WO2019000163A1 (zh) * 2017-06-26 2019-01-03 余祖江 精氨酸在制备抗肿瘤药物中的用途
CN111491937A (zh) * 2017-12-22 2020-08-04 广东新契生物医药科技有限公司 作为精氨酸酶抑制剂的杂环化合物
MA51837A (fr) * 2018-02-17 2021-06-16 Astrazeneca Ab Inhibiteurs de l'arginase et leurs procédés d'utilisation
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TWI723366B (zh) 2018-03-29 2021-04-01 波蘭商昂科艾倫迪治療法股份公司 二肽哌啶衍生物
WO2019205979A1 (zh) * 2018-04-27 2019-10-31 四川科伦博泰生物医药股份有限公司 非天然氨基酸类衍生物、包含其的药物组合物及其制备方法和用途
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BR112021015581A2 (pt) * 2019-02-08 2021-10-05 Astrazeneca Ab Inibidores de arginase e seus métodos de uso
US10967020B2 (en) * 2019-04-05 2021-04-06 King Saud University Method of synthesizing custard apple peel nanoparticles
CN112110944B (zh) * 2019-06-21 2022-02-11 南京谷睿生物科技有限公司 一种化合物及其制备方法和应用
CN110734456A (zh) * 2019-11-06 2020-01-31 南京谷睿生物科技有限公司 一种化合物及其制备方法和医药上的应用
TW202228720A (zh) 2020-12-22 2022-08-01 波蘭商昂科艾倫迪治療法股份公司 精胺酸酶抑制劑及其使用方法
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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021535111A (ja) * 2018-08-22 2021-12-16 アストラゼネカ・アクチエボラーグAstrazeneca Aktiebolag アルギナーゼインヒビタ及びその使用方法
JP7441210B2 (ja) 2018-08-22 2024-02-29 アストラゼネカ・アクチエボラーグ アルギナーゼインヒビタ及びその使用方法
US11952392B2 (en) 2018-08-22 2024-04-09 Astrazeneca Ab Arginase inhibitors and methods of use thereof
JP2022507474A (ja) * 2018-11-16 2022-01-18 アーカス バイオサイエンシーズ インコーポレイテッド Ａｒｇ１及び／又はａｒｇ２の阻害剤
JP7461350B2 (ja) 2018-11-16 2024-04-03 アーカス バイオサイエンシーズ インコーポレイテッド Ａｒｇ１及び／又はａｒｇ２の阻害剤
KR20220038105A (ko) * 2019-07-23 2022-03-25 아스트라제네카 아베 아르기나제 저해제 및 이의 사용 방법
JP2022541592A (ja) * 2019-07-23 2022-09-26 アストラゼネカ・アクチエボラーグ アルギナーゼ阻害剤及びその使用方法
JP7579324B2 (ja) 2019-07-23 2024-11-07 アストラゼネカ・アクチエボラーグ アルギナーゼ阻害剤及びその使用方法
KR102885194B1 (ko) 2019-07-23 2025-11-13 아스트라제네카 아베 아르기나제 저해제 및 이의 사용 방법

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WO2016210106A1 (en) 2016-12-29
UA123700C2 (uk) 2021-05-19
EA201890113A1 (ru) 2018-07-31
US20160375044A1 (en) 2016-12-29
US10398714B2 (en) 2019-09-03
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US20190343852A1 (en) 2019-11-14
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CA2990192A1 (en) 2016-12-29
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