JP2018520352A5 - - Google Patents

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Publication number
JP2018520352A5
JP2018520352A5 JP2017567207A JP2017567207A JP2018520352A5 JP 2018520352 A5 JP2018520352 A5 JP 2018520352A5 JP 2017567207 A JP2017567207 A JP 2017567207A JP 2017567207 A JP2017567207 A JP 2017567207A JP 2018520352 A5 JP2018520352 A5 JP 2018520352A5
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JP
Japan
Prior art keywords
aryl
alkylene
alkyl
pharmaceutical composition
heterocycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2017567207A
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English (en)
Japanese (ja)
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JP2018520352A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2016/038983 external-priority patent/WO2016210106A1/en
Publication of JP2018520352A publication Critical patent/JP2018520352A/ja
Publication of JP2018520352A5 publication Critical patent/JP2018520352A5/ja
Priority to JP2021128745A priority Critical patent/JP2021185146A/ja
Ceased legal-status Critical Current

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JP2017567207A 2015-06-23 2016-06-23 アルギナーゼ活性を阻害するための組成物および方法 Ceased JP2018520352A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021128745A JP2021185146A (ja) 2015-06-23 2021-08-05 アルギナーゼ活性を阻害するための組成物および方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562183524P 2015-06-23 2015-06-23
US62/183,524 2015-06-23
PCT/US2016/038983 WO2016210106A1 (en) 2015-06-23 2016-06-23 Compositions and methods for inhibiting arginase activity

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021128745A Division JP2021185146A (ja) 2015-06-23 2021-08-05 アルギナーゼ活性を阻害するための組成物および方法

Publications (2)

Publication Number Publication Date
JP2018520352A JP2018520352A (ja) 2018-07-26
JP2018520352A5 true JP2018520352A5 (enExample) 2019-07-25

Family

ID=57585664

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017567207A Ceased JP2018520352A (ja) 2015-06-23 2016-06-23 アルギナーゼ活性を阻害するための組成物および方法
JP2021128745A Withdrawn JP2021185146A (ja) 2015-06-23 2021-08-05 アルギナーゼ活性を阻害するための組成物および方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021128745A Withdrawn JP2021185146A (ja) 2015-06-23 2021-08-05 アルギナーゼ活性を阻害するための組成物および方法

Country Status (17)

Country Link
US (4) US10143699B2 (enExample)
EP (1) EP3313410A4 (enExample)
JP (2) JP2018520352A (enExample)
KR (1) KR20180021117A (enExample)
CN (1) CN107921051A (enExample)
AU (1) AU2016281620B2 (enExample)
CA (1) CA2990192A1 (enExample)
EA (1) EA201890113A1 (enExample)
IL (1) IL256352A (enExample)
MA (1) MA42269A (enExample)
MX (1) MX385315B (enExample)
MY (1) MY192605A (enExample)
PH (1) PH12017502391A1 (enExample)
SG (1) SG10202110144TA (enExample)
UA (1) UA123700C2 (enExample)
WO (1) WO2016210106A1 (enExample)
ZA (1) ZA201800328B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201503168VA (en) 2010-04-22 2015-06-29 Mars Inc Inhibitors of arginase and their therapeutic applications
HUE027317T2 (en) 2010-10-26 2016-10-28 Mars Inc Boronates as arginase inhibitors
UA123700C2 (uk) 2015-06-23 2021-05-19 Калітера Байосайєнсиз, Інк. Композиції і способи інгібування активності аргінази
HRP20201046T1 (hr) * 2015-10-30 2020-10-16 Calithera Biosciences, Inc. Sastavi i metode za inhibitivnu aktivnost arginase
PL417066A1 (pl) 2016-05-04 2017-11-06 Oncoarendi Therapeutics Spółka Z Ograniczoną Odpowiedzialnością Inhibitory arginazy oraz ich zastosowania terapeutyczne
KR20190104521A (ko) 2016-11-08 2019-09-10 칼리테라 바이오사이언시즈, 인코포레이티드 아르기나제 억제제 병용 요법들
PE20191541A1 (es) 2016-12-22 2019-10-23 Calithera Biosciences Inc Composiciones y metodos para inhibir la accion de la arginasa
CN108794517B (zh) * 2017-04-27 2021-03-30 南京谷睿生物科技有限公司 一种精氨酸酶抑制剂及其制备方法与用途
BR112019023582A2 (pt) 2017-05-12 2020-06-02 Calithera Biosciences Inc. Método de preparar (3r,4s)-3-acetamido-4-alil-n-(terc-butil)pirrolidina-3-carboxamida
WO2019000163A1 (zh) * 2017-06-26 2019-01-03 余祖江 精氨酸在制备抗肿瘤药物中的用途
CN111491937A (zh) * 2017-12-22 2020-08-04 广东新契生物医药科技有限公司 作为精氨酸酶抑制剂的杂环化合物
MA51837A (fr) * 2018-02-17 2021-06-16 Astrazeneca Ab Inhibiteurs de l'arginase et leurs procédés d'utilisation
UA127897C2 (uk) * 2018-03-05 2024-02-07 Аркус Байосайєнсіз, Інк. Інгібітори аргінази
TWI723366B (zh) 2018-03-29 2021-04-01 波蘭商昂科艾倫迪治療法股份公司 二肽哌啶衍生物
WO2019205979A1 (zh) * 2018-04-27 2019-10-31 四川科伦博泰生物医药股份有限公司 非天然氨基酸类衍生物、包含其的药物组合物及其制备方法和用途
JP7441210B2 (ja) * 2018-08-22 2024-02-29 アストラゼネカ・アクチエボラーグ アルギナーゼインヒビタ及びその使用方法
CA3120196A1 (en) * 2018-11-16 2020-05-22 Arcus Biosciences, Inc. Inhibitors of arg1 and/or arg2
WO2020104626A1 (en) * 2018-11-21 2020-05-28 Black Belt Tx Ltd Inhibitors of arginase
EP3917936A4 (en) * 2019-02-06 2022-12-14 Guangdong Newopp Biopharmaceuticals Co., Ltd. ALKYBORONIC ACIDS AS ARGINASE INHIBITORS
BR112021015581A2 (pt) * 2019-02-08 2021-10-05 Astrazeneca Ab Inibidores de arginase e seus métodos de uso
US10967020B2 (en) * 2019-04-05 2021-04-06 King Saud University Method of synthesizing custard apple peel nanoparticles
CN112110944B (zh) * 2019-06-21 2022-02-11 南京谷睿生物科技有限公司 一种化合物及其制备方法和应用
EP4004004A1 (en) * 2019-07-23 2022-06-01 AstraZeneca AB Arginase inhibitors and methods of use thereof
CN110734456A (zh) * 2019-11-06 2020-01-31 南京谷睿生物科技有限公司 一种化合物及其制备方法和医药上的应用
TW202228720A (zh) 2020-12-22 2022-08-01 波蘭商昂科艾倫迪治療法股份公司 精胺酸酶抑制劑及其使用方法
US20250099408A1 (en) 2022-01-21 2025-03-27 Sammy Oyoo OPIYO Improved suramin methods and compositions

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172896A (en) 1978-06-05 1979-10-30 Dainippon Pharmaceutical Co., Ltd. Methane-sulfonamide derivatives, the preparation thereof and composition comprising the same
GB9217295D0 (en) 1992-08-14 1992-09-30 Wellcome Found Controlled released tablets
GB9315856D0 (en) 1993-07-30 1993-09-15 Wellcome Found Stabilized pharmaceutical
US5358970A (en) 1993-08-12 1994-10-25 Burroughs Wellcome Co. Pharmaceutical composition containing bupropion hydrochloride and a stabilizer
US5541231A (en) 1993-07-30 1996-07-30 Glaxo Wellcome Inc. Stabilized Pharmaceutical
DE69818675T2 (de) 1997-07-29 2004-07-29 Alcon Laboratories, Inc., Fort Worth Galaktomannanpolymere und borat enthaltende augenarzneimittel
WO1999019295A1 (en) 1997-10-10 1999-04-22 Trustees Of The University Of Pennsylvania Compositions and methods for inhibiting arginase activity
JP2002501892A (ja) 1998-01-29 2002-01-22 セプラコア インコーポレーテッド 光学的に純粋な（−）−ビュープロピオンの薬学的使用
US20040063666A1 (en) 1998-10-09 2004-04-01 David Christianson Compositions for inhibiting arginase activity
US8889112B2 (en) 1999-09-16 2014-11-18 Ocularis Pharma, Llc Ophthalmic formulations including selective alpha 1 antagonists
CA2415174A1 (en) * 2000-07-06 2002-01-17 Thomas W. Bell Methods and kits for the detection of arginine compounds
CA2431080A1 (en) 2003-06-02 2004-12-02 Catherine Adele O'brien Enhancement of anticancer immunity through inhibition of arginase
US6933289B2 (en) 2003-07-01 2005-08-23 Allergan, Inc. Inhibition of irritating side effects associated with use of a topical ophthalmic medication
ES2332049T5 (es) 2003-08-07 2014-03-27 Allergan, Inc. Composiciones de administración de sustancias terapéuticas en los ojos
US20050059744A1 (en) 2003-09-12 2005-03-17 Allergan, Inc. Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions
US20090298912A1 (en) 2005-07-01 2009-12-03 The Johns Hopkins University Arginase II: A Target treatment of aging heart and heart failure
CN101755130B (zh) 2007-07-12 2012-10-17 山洋电气株式会社 双重反转式轴流鼓风机
SMT201900320T1 (it) 2009-01-26 2019-07-11 Astrazeneca Uk Ltd Inibitori dell'arginasi e metodi di utilizzo
SG10201503168VA (en) 2010-04-22 2015-06-29 Mars Inc Inhibitors of arginase and their therapeutic applications
HUE027317T2 (en) * 2010-10-26 2016-10-28 Mars Inc Boronates as arginase inhibitors
WO2012091757A1 (en) 2010-12-31 2012-07-05 Corridor Pharmaceuticals, Inc. Arginase inhibitors and methods of use thereof
JP5993459B2 (ja) 2011-10-19 2016-09-14 マーズ インコーポレイテッド アルギナーゼ阻害剤およびそれらの治療用途
KR20140077963A (ko) 2011-10-20 2014-06-24 글락소스미스클라인 엘엘씨 시르투인 조절제로서의 치환된 비시클릭 아자-헤테로사이클 및 유사체
JP6152167B2 (ja) * 2012-04-18 2017-06-21 マーズ インコーポレイテッド アルギナーゼ阻害剤としての環拘束性類似体
CN105848680A (zh) 2013-10-25 2016-08-10 药品循环有限责任公司 使用布鲁顿酪氨酸激酶抑制剂和免疫疗法的治疗
CN105879030A (zh) 2014-09-30 2016-08-24 复旦大学 治疗肿瘤的增效药物复合物及其制备方法
CN107405404A (zh) 2015-03-20 2017-11-28 塞米·欧尤·奥皮约 苏拉明和精氨酸酶抑制剂在恶性肿瘤中的用途
UA123700C2 (uk) 2015-06-23 2021-05-19 Калітера Байосайєнсиз, Інк. Композиції і способи інгібування активності аргінази

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