|
FR2338043A1
(fr)
|
1976-01-13 |
1977-08-12 |
Delmar Chem |
Derives de 4-arylpiperidine et procedes de production
|
|
US4132710A
(en)
|
1976-12-20 |
1979-01-02 |
Ayerst, Mckenna And Harrison, Ltd. |
[2]Benzopyrano[3,4-c]pyridines and process therefor
|
|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
IN164232B
(cg-RX-API-DMAC10.html)
|
1986-04-11 |
1989-02-04 |
Hoechst India |
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
JP2691986B2
(ja)
|
1987-08-28 |
1997-12-17 |
チッソ株式会社 |
ピリジン骨格を有する光学活性化合物の製造法
|
|
DE3743824C2
(de)
|
1987-12-23 |
1997-03-06 |
Hoechst Ag |
Verfahren zur enzymatischen Racematspaltung von racemischen Alkoholen mit/in Vinylestern durch Umesterung
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
DE3836676A1
(de)
|
1988-10-28 |
1990-05-03 |
Hoechst Ag |
Die verwendung von 4h-1-benzopyran-4-on-derivaten, neue 4h-1-benzopyran-4-on-derivate und diese enthaltende arzneimittel
|
|
US5284856A
(en)
|
1988-10-28 |
1994-02-08 |
Hoechst Aktiengesellschaft |
Oncogene-encoded kinases inhibition using 4-H-1-benzopyran-4-one derivatives
|
|
GB8827305D0
(en)
|
1988-11-23 |
1988-12-29 |
British Bio Technology |
Compounds
|
|
EP0739904A1
(en)
|
1989-06-29 |
1996-10-30 |
Medarex, Inc. |
Bispecific reagents for aids therapy
|
|
US5804604A
(en)
|
1989-12-21 |
1998-09-08 |
Biogen, Inc. |
Tat-derived transport polypeptides and fusion proteins
|
|
US5670617A
(en)
|
1989-12-21 |
1997-09-23 |
Biogen Inc |
Nucleic acid conjugates of tat-derived transport polypeptides
|
|
EP1690935A3
(en)
|
1990-01-12 |
2008-07-30 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
ES2246502T3
(es)
|
1990-08-29 |
2006-02-16 |
Genpharm International, Inc. |
Animales no humanos transgenicos capaces de producir anticuerpos heterologos.
|
|
JPH0641075A
(ja)
|
1990-09-01 |
1994-02-15 |
Kazuo Achinami |
新規な１，４−ジヒドロピリジン化合物及びその製造方法
|
|
JPH05192145A
(ja)
|
1991-04-02 |
1993-08-03 |
Hoechst Ag |
固定化生体触媒、その製造およびカラムリアクター中でのエステル合成におけるその使用
|
|
WO1992020373A1
(en)
|
1991-05-14 |
1992-11-26 |
Repligen Corporation |
Heteroconjugate antibodies for treatment of hiv infection
|
|
FI941572L
(fi)
|
1991-10-07 |
1994-05-27 |
Oncologix Inc |
Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenetelmä
|
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
|
CA2372813A1
(en)
|
1992-02-06 |
1993-08-19 |
L.L. Houston |
Biosynthetic binding protein for cancer marker
|
|
ES2301158T3
(es)
|
1992-07-24 |
2008-06-16 |
Amgen Fremont Inc. |
Produccion de anticuerpos xenogenicos.
|
|
ATE139900T1
(de)
|
1992-11-13 |
1996-07-15 |
Idec Pharma Corp |
Therapeutische verwendung von chimerischen und markierten antikörper gegen menschlichen b lymphozyt beschränkter differenzierung antigen für die behandlung von b-zell-lymphoma
|
|
US6177401B1
(en)
|
1992-11-13 |
2001-01-23 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften |
Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis
|
|
US5455258A
(en)
|
1993-01-06 |
1995-10-03 |
Ciba-Geigy Corporation |
Arylsulfonamido-substituted hydroxamic acids
|
|
IL112248A0
(en)
|
1994-01-25 |
1995-03-30 |
Warner Lambert Co |
Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
|
|
GB9422836D0
(en)
|
1994-11-11 |
1995-01-04 |
Wainscoat James |
Monitoring malignant disease
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US5863949A
(en)
|
1995-03-08 |
1999-01-26 |
Pfizer Inc |
Arylsulfonylamino hydroxamic acid derivatives
|
|
CA2218503C
(en)
|
1995-04-20 |
2001-07-24 |
Pfizer Inc. |
Arylsulfonyl hydroxamic acid derivatives
|
|
CA2219361C
(en)
|
1995-04-27 |
2012-02-28 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
WO1996034096A1
(en)
|
1995-04-28 |
1996-10-31 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
US5880141A
(en)
|
1995-06-07 |
1999-03-09 |
Sugen, Inc. |
Benzylidene-Z-indoline compounds for the treatment of disease
|
|
AU705563B2
(en)
|
1995-07-28 |
1999-05-27 |
Marie Curie Cancer Care |
Transport proteins and their uses
|
|
GB9520822D0
(en)
|
1995-10-11 |
1995-12-13 |
Wellcome Found |
Therapeutically active compounds
|
|
US5733920A
(en)
|
1995-10-31 |
1998-03-31 |
Mitotix, Inc. |
Inhibitors of cyclin dependent kinases
|
|
GB9624482D0
(en)
|
1995-12-18 |
1997-01-15 |
Zeneca Phaema S A |
Chemical compounds
|
|
DK0780386T3
(da)
|
1995-12-20 |
2003-02-03 |
Hoffmann La Roche |
Matrixmetalloproteaseinhibitorer
|
|
EP0888458A4
(en)
|
1996-02-20 |
2004-05-06 |
Sloan Kettering Institutefor C |
COMBINATION OF PKC INHIBITORS AND THERAPEUTIC AGENTS FOR TREATING CANCER
|
|
NZ331191A
(en)
|
1996-03-05 |
2000-03-27 |
Zeneca Ltd |
4-anilinoquinazoline derivatives and pharmaceutical compositions thereof
|
|
US6087366A
(en)
|
1996-03-07 |
2000-07-11 |
The Trustees Of Columbia University In The City Of New York |
Use of flavopiridol or a pharmaceutically acceptable salt thereof for inhibiting cell damage or cell death
|
|
US5849733A
(en)
|
1996-05-10 |
1998-12-15 |
Bristol-Myers Squibb Co. |
2-thio or 2-oxo flavopiridol analogs
|
|
EP0818442A3
(en)
|
1996-07-12 |
1998-12-30 |
Pfizer Inc. |
Cyclic sulphone derivatives as inhibitors of metalloproteinases and of the production of tumour necrosis factor
|
|
US6391874B1
(en)
|
1996-07-13 |
2002-05-21 |
Smithkline Beecham Corporation |
Fused heterocyclic compounds as protein tyrosine kinase inhibitors
|
|
AR007855A1
(es)
|
1996-07-13 |
1999-11-24 |
Glaxo Group Ltd |
Compuestos heterociclicos fusionados como inhibidores de proteina tirosina quinasa, sus metodos de preparacion, intermediarios, uso en medicinay composiciones farmaceuticas que los contienen
|
|
HRP970371A2
(en)
|
1996-07-13 |
1998-08-31 |
Kathryn Jane Smith |
Heterocyclic compounds
|
|
EP0923585B1
(en)
|
1996-07-18 |
2002-05-08 |
Pfizer Inc. |
Phosphinate based inhibitors of matrix metalloproteases
|
|
EP0922030A1
(en)
|
1996-08-23 |
1999-06-16 |
Pfizer Inc. |
Arylsulfonylamino hydroxamic acid derivatives
|
|
US5965703A
(en)
|
1996-09-20 |
1999-10-12 |
Idun Pharmaceuticals |
Human bad polypeptides, encoding nucleic acids and methods of use
|
|
US5908934A
(en)
|
1996-09-26 |
1999-06-01 |
Bristol-Myers Squibb Company |
Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs
|
|
ID18494A
(id)
|
1996-10-02 |
1998-04-16 |
Novartis Ag |
Turunan pirazola leburan dan proses pembuatannya
|
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
|
US6077864A
(en)
|
1997-01-06 |
2000-06-20 |
Pfizer Inc. |
Cyclic sulfone derivatives
|
|
HUP0000852A2
(hu)
|
1997-02-03 |
2001-05-28 |
Pfizer Products Inc. |
Aril-szulfonil-amino-hidroxámsav-származékok, valamint e vegyületeket tartalmazó gyógyászati készítmények
|
|
ES2301194T3
(es)
|
1997-02-05 |
2008-06-16 |
Warner-Lambert Company Llc |
Pirido 2,3-d pirimidinas y 4-aminopirimidinas como inhibidores de la proliferacion celular.
|
|
JP2000507975A
(ja)
|
1997-02-07 |
2000-06-27 |
ファイザー・インク |
Ｎ−ヒドロキシ−β−スルホニルプロピオンアミド誘導体類及びそれらのマトリックスメタロプロテイナーゼ阻害薬としての使用
|
|
NZ336836A
(en)
|
1997-02-11 |
2001-02-23 |
Pfizer |
Arylsulfonyl hydroxamic acid derivatives suitable for a broad range of medicinal treatments
|
|
GB9704444D0
(en)
|
1997-03-04 |
1997-04-23 |
Isis Innovation |
Non-invasive prenatal diagnosis
|
|
CA2289102A1
(en)
|
1997-05-07 |
1998-11-12 |
Sugen, Inc. |
2-indolinone derivatives as modulators of protein kinase activity
|
|
CA2291709A1
(en)
|
1997-05-30 |
1998-12-03 |
Merck & Co., Inc. |
Novel angiogenesis inhibitors
|
|
TR200000368T2
(tr)
|
1997-08-08 |
2000-07-21 |
Pfizer Products Inc. |
Ariloksiariarilsülfonilamino hidroksamik asit türevleri.
|
|
DE69838172T2
(de)
|
1997-08-22 |
2008-04-10 |
Astrazeneca Ab |
Oxindolylchinazolinderivate als angiogenesehemmer
|
|
US7064193B1
(en)
|
1997-09-17 |
2006-06-20 |
The Walter And Eliza Hall Institute Of Medical Research |
Therapeutic molecules
|
|
WO1999016787A1
(en)
|
1997-09-26 |
1999-04-08 |
Washington University |
Cell death agonists
|
|
AU744939B2
(en)
|
1997-09-26 |
2002-03-07 |
Merck & Co., Inc. |
Novel angiogenesis inhibitors
|
|
SK6652000A3
(en)
|
1997-11-11 |
2002-05-09 |
Pfizer Prod Inc |
Thienopyrimidine and thienopyridine derivatives useful as anticancer agents
|
|
GB9725782D0
(en)
|
1997-12-05 |
1998-02-04 |
Pfizer Ltd |
Therapeutic agents
|
|
RS49779B
(sr)
|
1998-01-12 |
2008-06-05 |
Glaxo Group Limited, |
Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
|
|
GB9800575D0
(en)
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
|
US6437136B2
(en)
|
1998-01-23 |
2002-08-20 |
Aventis Pharma Deutschland Gmbh |
Process for the preparation of (−)cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)piperidine
|
|
DE19802449A1
(de)
|
1998-01-23 |
1999-07-29 |
Hoechst Marion Roussel De Gmbh |
Verfahren zur Herstellung von (-)cis-3-Hydroxy-1-methyl-4-(2,4,6-trimethoxypyhenyl)-piperidin
|
|
GB9801690D0
(en)
|
1998-01-27 |
1998-03-25 |
Pfizer Ltd |
Therapeutic agents
|
|
DE19809649A1
(de)
|
1998-03-06 |
1999-09-09 |
Hoechst Marion Roussel De Gmbh |
Verfahren zur enzymatischen Enantiomeren-Trennung von 3(R)- und 3(S)-Hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydro-pyridin bzw. der Carbonsäureester
|
|
JP4462654B2
(ja)
|
1998-03-26 |
2010-05-12 |
ソニー株式会社 |
映像素材選択装置及び映像素材選択方法
|
|
PA8469501A1
(es)
|
1998-04-10 |
2000-09-29 |
Pfizer Prod Inc |
Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico
|
|
PA8469401A1
(es)
|
1998-04-10 |
2000-05-24 |
Pfizer Prod Inc |
Derivados biciclicos del acido hidroxamico
|
|
US20020029391A1
(en)
|
1998-04-15 |
2002-03-07 |
Claude Geoffrey Davis |
Epitope-driven human antibody production and gene expression profiling
|
|
KR100743287B1
(ko)
|
1998-05-29 |
2007-07-26 |
수젠, 인크. |
피롤기로 치환된 2-인돌리논 단백질 인산화 효소 억제제
|
|
UA60365C2
(uk)
|
1998-06-04 |
2003-10-15 |
Пфайзер Продактс Інк. |
Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
|
|
FR2780056B1
(fr)
|
1998-06-18 |
2000-08-04 |
Hoechst Marion Roussel Inc |
Nouveau procede de preparation de derives de la 4-phenyl-1-2 3,6-tetrahydropyridine et les produits imtermediaires mis en oeuvre
|
|
DE69923322T2
(de)
|
1998-07-30 |
2005-12-22 |
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. |
Verwendung von propionyl-l-carnitin und acetyl-l-carnitin zur herstellung von arzneimittel mit antikrebs wirkung
|
|
US6268499B1
(en)
|
1998-08-10 |
2001-07-31 |
Hoffman-La Roche Inc. |
Process and intermediates for preparation of substituted piperidine-epoxides
|
|
AU1029500A
(en)
|
1998-08-29 |
2000-03-21 |
Miklos Ghyczy |
Pharmaceutical and/or diet product
|
|
EP1004578B1
(en)
|
1998-11-05 |
2004-02-25 |
Pfizer Products Inc. |
5-oxo-pyrrolidine-2-carboxylic acid hydroxamide derivatives
|
|
UA71945C2
(en)
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
|
US6399633B1
(en)
|
1999-02-01 |
2002-06-04 |
Aventis Pharmaceuticals Inc. |
Use of 4-H-1-benzopryan-4-one derivatives as inhibitors of smooth muscle cell proliferation
|
|
EP1210098A1
(en)
|
1999-04-07 |
2002-06-05 |
Thomas Jefferson University |
Enhancement of peptide cellular uptake
|
|
US6511993B1
(en)
|
1999-06-03 |
2003-01-28 |
Kevin Neil Dack |
Metalloprotease inhibitors
|
|
WO2001012661A2
(en)
|
1999-08-16 |
2001-02-22 |
The Government Of The United States Of America, Asrepresented By The Secretary, Department Of Healthand Human Services, The National Institutes Of Health |
RECEPTOR-MEDIATED UPTAKE OF AN EXTRACELLULAR BCL-xL FUSION PROTEIN INHIBITS APOPTOSIS
|
|
US6576647B2
(en)
|
2000-01-18 |
2003-06-10 |
Aventis Pharmaceuticals Inc. |
Pseudopolymorph of (—)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4R-(3S-hydroxy -1-methyl)piperidinyl]-4H-1-benzopyran-4-one
|
|
US6821990B2
(en)
|
2000-01-18 |
2004-11-23 |
Aventis Pharma Deutschland Gmbh |
Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5, 7-dihydroxy-8 [4R-(3S-hydroxy-1-M ethyl) piperidinyl]-4H-1-benzopyran-4-one
|
|
HRP20020751B1
(hr)
|
2000-02-15 |
2011-01-31 |
Sugen |
Pirolom supstituirani 2-indolinoni kao inhibitori protein kinaze
|
|
WO2002020568A2
(en)
|
2000-09-06 |
2002-03-14 |
Abbott Laboratories |
Mutant peptides derived from bad and their use to identify substances which bind to a member of the bcl-2 family of proteins
|
|
AU2002228849A1
(en)
|
2000-12-08 |
2002-06-18 |
Bristol-Myers Squibb Pharma Company |
Semicarbazides and their uses as cyclin dependent kinase inhibitors
|
|
WO2002069995A2
(en)
|
2001-02-16 |
2002-09-12 |
Medical College Of Georgia Research Institute, Inc. |
Use of trail and antiprogestins for treating cancer
|
|
AU2002303164A1
(en)
|
2001-03-23 |
2002-10-08 |
Protarga, Inc. |
Fatty amine drug conjugates
|
|
AU2002305099A1
(en)
|
2001-03-23 |
2002-10-08 |
Protarga, Inc. |
Fatty alcohol drug conjugates
|
|
EP1436406A4
(en)
|
2001-09-24 |
2004-10-13 |
Blood Ct Res Foundation |
METHOD FOR MODULATING OR EXAMINING THE KU70 MIRROR IN CELLS
|
|
KR20030026069A
(ko)
|
2001-09-24 |
2003-03-31 |
주식회사 엘지생명과학 |
티엔에프계 단백질과 플라보피리돌의 조합에 의한 암세포특이적인 세포사멸 유도용 조성물
|
|
WO2003040168A2
(en)
|
2001-11-06 |
2003-05-15 |
Enanta Pharmaceuticals, Inc. |
Methods and compositions for identifying peptide aptamers capable of altering a cell phenotype
|
|
WO2003057158A2
(en)
|
2001-12-31 |
2003-07-17 |
Dana-Farber Cancer Institute, Inc. |
Method of treating apoptosis and compositions thereof
|
|
CA2478047C
(en)
|
2002-03-01 |
2014-01-21 |
Immunomedics, Inc. |
Rs7 antibodies
|
|
US20040106647A1
(en)
|
2002-06-28 |
2004-06-03 |
Schneider Michael D. |
Modulators of Cdk9 as a therapeutic target in cardiac hypertrophy
|
|
CA2496400A1
(en)
|
2002-09-09 |
2004-03-18 |
Dana-Farber Cancer Institute, Inc. |
Bh3 peptides and method of use thereof
|
|
WO2004058804A1
(en)
|
2002-12-24 |
2004-07-15 |
Walter And Eliza Hall Institute Of Medical Research |
Peptides and therapeutic uses thereof
|
|
US7452901B2
(en)
|
2003-04-25 |
2008-11-18 |
Gilead Sciences, Inc. |
Anti-cancer phosphonate analogs
|
|
EP1620109A2
(en)
|
2003-04-25 |
2006-02-01 |
Gilead Sciences, Inc. |
Kinase inhibitor phosphonate conjugates
|
|
GB0315259D0
(en)
|
2003-06-30 |
2003-08-06 |
Cyclacel Ltd |
Use
|
|
CN1302004C
(zh)
|
2003-08-22 |
2007-02-28 |
浙江海正药业股份有限公司 |
一种阿糖胞苷的制备方法
|
|
EP1680443B9
(en)
|
2003-11-05 |
2014-09-03 |
Dana-Farber Cancer Institute, Inc. |
Stabilized alpha helical peptides and uses thereof
|
|
WO2006069186A2
(en)
|
2004-12-22 |
2006-06-29 |
The Ohio State Research Foundation |
Small molecule bcl-xl/bcl-2 binding inhibitors
|
|
WO2006101846A1
(en)
|
2005-03-16 |
2006-09-28 |
Aventis Pharmaceuticals Inc. |
Dosing regimen of flavopiridol for treating cancer in particular cll
|
|
WO2006099667A1
(en)
|
2005-03-21 |
2006-09-28 |
The Walter And Eliza Hall Institute Of Medical Research |
Prophylactic and therapeutic agents and uses therefor
|
|
US7750000B2
(en)
|
2005-09-02 |
2010-07-06 |
Bayer Schering Pharma Ag |
Substituted imidazo[1,2b]pyridazines as kinase inhibitors, their preparation and use as medicaments
|
|
US8221966B2
(en)
|
2006-03-31 |
2012-07-17 |
Dana Farber Cancer Institute |
Methods of determining cellular chemosensitivity
|
|
US20090142337A1
(en)
|
2006-05-08 |
2009-06-04 |
Astex Therapeutics Limited |
Pharmaceutical Combinations of Diazole Derivatives for Cancer Treatment
|
|
US9360473B2
(en)
|
2006-08-16 |
2016-06-07 |
Eutropics Pharmaceuticals, Inc. |
Assay system to identify therapeutic agents
|
|
MX2009009117A
(es)
|
2007-03-01 |
2009-09-03 |
Supergen Inc |
Derivados de pirimidin-2,4-diamina y su uso como inhibidores de la cinasa jak2.
|
|
GB0706633D0
(en)
|
2007-04-04 |
2007-05-16 |
Cyclacel Ltd |
Combination
|
|
RU2438664C2
(ru)
|
2007-05-15 |
2012-01-10 |
Пирамал Лайф Сайнсиз Лимитед |
Синергическая фармацевтическая комбинация для лечения рака
|
|
CA2687204C
(en)
|
2007-05-15 |
2015-11-24 |
Piramal Life Sciences Limited |
A synergistic pharmaceutical combination for the treatment of cancer
|
|
WO2009014642A1
(en)
|
2007-07-19 |
2009-01-29 |
Amgen Inc. |
Combination of a de novo purine biosynthesis inhibitor and a cyclin dependent kinase inhibitor for the treatment of cancer
|
|
EP2208061B1
(en)
|
2007-09-26 |
2017-11-08 |
Dana Farber Cancer Institute |
Methods and compositions for modulating bcl-2 family polypeptides
|
|
CA2708264C
(en)
|
2007-12-10 |
2018-07-03 |
Sunesis Pharmaceuticals, Inc. |
Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders
|
|
TWI378781B
(en)
|
2008-03-12 |
2012-12-11 |
Jung Tang Huang |
A belt integrated with stress sensing and output reaction
|
|
WO2009137664A1
(en)
|
2008-05-07 |
2009-11-12 |
Eutropics Pharmaceuticals, Inc. |
Antibodies specific to heterodimers of bcl-2 family and uses thereof
|
|
PL2307002T3
(pl)
|
2008-06-09 |
2013-05-31 |
Cyclacel Ltd |
Kombinacje sapacytabiny lub cndac z inhibitorami metylotransferazy dna, takimi jak decytabina i prokaina
|
|
CA2751293A1
(en)
|
2009-02-11 |
2010-08-19 |
Abbott Laboratories |
Methods and compositions for identifying, classifying and monitoring subject having bcl-2 family inhibitor-resistant tumors and cancers
|
|
PL3912643T3
(pl)
|
2009-02-13 |
2023-01-23 |
Immunomedics Inc. |
Immunokoniugaty z połączeniem rozszczepialnym wewnątrzkomórkowo
|
|
WO2010147961A1
(en)
|
2009-06-15 |
2010-12-23 |
Precision Therapeutics, Inc. |
Methods and markers for predicting responses to chemotherapy
|
|
WO2011088137A2
(en)
|
2010-01-12 |
2011-07-21 |
H. Lee Moffitt Cancer Center & Research Institute |
Bad pathway gene signature
|
|
US8372819B2
(en)
|
2010-04-11 |
2013-02-12 |
Salk Institute For Biological Studies |
Methods and compositions for targeting skip
|
|
CN103154246B
(zh)
|
2010-05-14 |
2015-11-25 |
达那-法伯癌症研究所 |
用于治疗白血病的组合物和方法
|
|
SG180031A1
(en)
|
2010-10-15 |
2012-05-30 |
Agency Science Tech & Res |
Combination treatment of cancer
|
|
EP2655334B1
(en)
|
2010-12-22 |
2018-10-03 |
Eutropics Pharmaceuticals, Inc. |
Compositions and methods useful for treating diseases
|
|
WO2012122370A2
(en)
|
2011-03-08 |
2012-09-13 |
Eutropics Pharmaceuticals, Inc. |
Compositions and methods useful for treating diseases
|
|
CN103608012A
(zh)
|
2011-06-14 |
2014-02-26 |
诺华股份有限公司 |
在癌症如骨髓增殖性肿瘤治疗中的帕比司他与鲁索利替尼的组合
|
|
EP2561867A1
(en)
|
2011-08-22 |
2013-02-27 |
Lead Discovery Center GmbH |
CDK9 inhibitors in the treatment of midline carcinoma
|
|
US9012215B2
(en)
|
2011-09-22 |
2015-04-21 |
The Johns Hopkins University |
Methods for identifying leukemia stem cells and distinguishing them from normal hematopietic stem cells in patients with acute myeloid leukemia: uses in diagnosis, treatment, and research
|
|
US20130122492A1
(en)
|
2011-11-14 |
2013-05-16 |
Kellbenx Inc. |
Detection, isolation and analysis of rare cells in biological fluids
|
|
WO2013082660A1
(en)
|
2011-12-09 |
2013-06-13 |
Alfred Health |
Prediction method
|
|
WO2013138702A2
(en)
|
2012-03-15 |
2013-09-19 |
Bristol-Myers Squibb Company |
Methods for predicting gastrointestinal immune-related adverse events (gi-irae) in patients treated with modulation of the co-stimulatory pathway
|
|
AU2013235425B2
(en)
|
2012-03-20 |
2017-09-21 |
Dana Farber Cancer Institute, Inc. |
Inhibition of MCL-1 and/or BFL-1/A1
|
|
WO2013170176A2
(en)
*
|
2012-05-10 |
2013-11-14 |
Eutropics Pharmaceuticals, Inc. |
Surrogate functional diagnostics test for cancer
|
|
MX347755B
(es)
|
2012-05-11 |
2017-05-10 |
Momentum Dynamics Corp |
Metodo y aparato para generar reactancia ajustable.
|
|
WO2013182519A1
(en)
|
2012-06-04 |
2013-12-12 |
Universitaet Basel |
Combination of lysosomotropic or autophagy modulating agents and a gsk-3 inhibitor for treatment of cancer
|
|
WO2013188355A1
(en)
|
2012-06-12 |
2013-12-19 |
Merck Sharp & Dohme Corp. |
Cdk inhibitor for treating refractory chronic lymphocytic leukemia
|
|
EP2863920B1
(en)
|
2012-06-20 |
2023-03-22 |
Eutropics Pharmaceuticals, Inc. |
Quinoline derivatives for use in the tratment of breast cancer
|
|
WO2013188978A1
(en)
|
2012-06-20 |
2013-12-27 |
Cytospan Technologies Corporation |
Apparatus and method for quantification of replicative lifespan and observation of senescene
|
|
WO2014047342A1
(en)
|
2012-09-19 |
2014-03-27 |
Dana-Farber Cancer Institute, Inc. |
Dynamic bh3 profiling
|
|
US9241941B2
(en)
|
2012-09-20 |
2016-01-26 |
Memorial Sloan-Kettering Cancer Center |
Methods for treatment of lymphomas with mutations in cell cycle genes
|
|
SG11201502757QA
(en)
|
2012-10-09 |
2015-05-28 |
Igenica Biotherapeutics Inc |
Anti-c16orf54 antibodies and methods of use thereof
|
|
EP2912178B1
(en)
|
2012-10-25 |
2020-06-17 |
Whitehead Institute For Biomedical Research |
Super-enhancers and methods of use thereof
|
|
WO2015010094A1
(en)
|
2013-07-18 |
2015-01-22 |
Eutropics Pharmaceuticals, Inc. |
Differential bh3 mitochondrial profiling
|
|
US10732182B2
(en)
|
2013-08-01 |
2020-08-04 |
Eutropics Pharmaceuticals, Inc. |
Method for predicting cancer sensitivity
|
|
AU2014323526B2
(en)
|
2013-09-19 |
2020-07-23 |
Dana-Farber Cancer Institute, Inc. |
Methods of BH3 profiling
|
|
CA2920192A1
(en)
|
2013-09-27 |
2015-04-02 |
Immunomedics, Inc. |
Anti-trop-2 antibody-drug conjugates and uses thereof
|
|
AU2014342269B2
(en)
|
2013-10-30 |
2020-02-27 |
Eutropics Pharmaceuticals, Inc. |
Methods for determining chemosensitivity and chemotoxicity
|
|
US11446309B2
(en)
|
2013-11-08 |
2022-09-20 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy for cancer using bromodomain and extra-terminal (BET) protein inhibitors
|
|
US9925192B2
(en)
|
2014-02-28 |
2018-03-27 |
Merck Sharp & Dohme Corp. |
Method for treating cancer
|
|
WO2015161247A1
(en)
|
2014-04-17 |
2015-10-22 |
Igenica Biotherapeutics, Inc. |
Humanized anti-c16orf54 antibodies and methods of use thereof
|
|
US10577417B2
(en)
|
2014-09-17 |
2020-03-03 |
Novartis Ag |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
US10300073B2
(en)
|
2014-10-14 |
2019-05-28 |
The Regents Of The University Of California |
Use of CDK9 and BRD4 inhibitors to inhibit inflammation
|
|
MX385762B
(es)
|
2014-11-07 |
2025-03-18 |
Sumitomo Pharma Oncology Inc |
Métodos para el control transcripcional objetivo en regiones del super mejorador.
|
|
WO2016115105A1
(en)
|
2015-01-12 |
2016-07-21 |
Eutropics Pharmaceuticals, Inc. |
Context dependent diagnostics test for guiding cancer treatment
|
|
EP3258941A4
(en)
|
2015-02-17 |
2018-09-26 |
Cantex Pharmaceuticals, Inc. |
Treatment of cancers and hematopoietic stem cell disorders privileged by cxcl12-cxcr4 interaction
|
|
EP3270945A4
(en)
|
2015-03-18 |
2018-09-05 |
Massachusetts Institute of Technology |
Selective mcl-1 binding peptides
|
|
WO2016154380A1
(en)
|
2015-03-24 |
2016-09-29 |
Eutropics Pharmaceuticals, Inc. |
Surrogate functional biomarker for solid tumor cancer
|
|
WO2016161248A1
(en)
|
2015-04-02 |
2016-10-06 |
Tolero Pharmaceuticals, Inc. |
Targeting pim kinases in combination with btk inhibition
|
|
AU2016252609B2
(en)
*
|
2015-04-20 |
2022-06-30 |
Sumitomo Pharma Oncology, Inc. |
Predicting response to alvocidib by mitochondrial profiling
|
|
AU2016255749B2
(en)
|
2015-04-27 |
2021-10-14 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for assessing toxicity using Dynamic BH3 profiling
|
|
HUE045585T2
(hu)
|
2015-05-18 |
2020-01-28 |
Tolero Pharmaceuticals Inc |
Megnövelt biológiai hozzáférhetõséggel rendelkezõ Alvocidib gyógyszer-elõanyagok
|
|
AU2016301315C1
(en)
|
2015-08-03 |
2022-07-07 |
Sumitomo Pharma Oncology, Inc. |
Combination therapies for treatment of cancer
|
|
WO2017075349A2
(en)
|
2015-10-30 |
2017-05-04 |
Massachusetts Institute Of Technology |
Selective mcl-1 binding peptides
|
|
CN105919955A
(zh)
|
2016-06-13 |
2016-09-07 |
佛山市腾瑞医药科技有限公司 |
一种鲁索利替尼制剂及其应用
|
|
WO2018094275A1
(en)
|
2016-11-18 |
2018-05-24 |
Tolero Pharmaceuticals, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
|
CA3047557A1
(en)
|
2016-12-19 |
2018-06-28 |
Tolero Pharmaceuticals, Inc. |
Profiling peptides and methods for sensitivity profiling
|
|
JP7196160B2
(ja)
|
2017-09-12 |
2022-12-26 |
スミトモ ファーマ オンコロジー， インコーポレイテッド |
Ｍｃｌ－１阻害剤アルボシジブを用いた、ｂｃｌ－２阻害剤に対して非感受性である癌の治療レジメン
|
|
US20190314357A1
(en)
|
2018-04-13 |
2019-10-17 |
Tolero Pharmaceuticals, Inc. |
Cyclin-dependent kinase inhibitors in combination with anthracyclines for treatment of cancer
|