JP2018515492A5 - - Google Patents
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- Publication number
- JP2018515492A5 JP2018515492A5 JP2017557413A JP2017557413A JP2018515492A5 JP 2018515492 A5 JP2018515492 A5 JP 2018515492A5 JP 2017557413 A JP2017557413 A JP 2017557413A JP 2017557413 A JP2017557413 A JP 2017557413A JP 2018515492 A5 JP2018515492 A5 JP 2018515492A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- alkyl
- acceptable salt
- membered
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 0 *C(N(*)C(c1c(*)c(*)c(-c2n[o]c(C(F)(F)F)n2)c(*)c1*)=O)=* Chemical compound *C(N(*)C(c1c(*)c(*)c(-c2n[o]c(C(F)(F)F)n2)c(*)c1*)=O)=* 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562158379P | 2015-05-07 | 2015-05-07 | |
| US62/158,379 | 2015-05-07 | ||
| PCT/US2016/031329 WO2016179550A1 (en) | 2015-05-07 | 2016-05-06 | Histone deacetylase inhibitors and compositions and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018515492A JP2018515492A (ja) | 2018-06-14 |
| JP2018515492A5 true JP2018515492A5 (enExample) | 2019-06-13 |
| JP6782255B2 JP6782255B2 (ja) | 2020-11-11 |
Family
ID=57218066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017557413A Expired - Fee Related JP6782255B2 (ja) | 2015-05-07 | 2016-05-06 | ヒストンデアセチラーゼ阻害薬及び組成物並びにそれらの使用の方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10047073B2 (enExample) |
| EP (1) | EP3291809B1 (enExample) |
| JP (1) | JP6782255B2 (enExample) |
| KR (1) | KR20180002730A (enExample) |
| CN (1) | CN107735087B (enExample) |
| AU (1) | AU2016256917B2 (enExample) |
| BR (1) | BR112017023710B1 (enExample) |
| CA (1) | CA2984621C (enExample) |
| EA (1) | EA035592B1 (enExample) |
| IL (1) | IL255449B2 (enExample) |
| MX (1) | MX379817B (enExample) |
| WO (1) | WO2016179550A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA035592B1 (ru) * | 2015-05-07 | 2020-07-13 | Сиэйчдиай Фаундэйшн, Инк. | Ингибиторы деацетилаз гистонов и композиции и способы их применения |
| CA2984618C (en) | 2015-05-07 | 2024-01-09 | Chdi Foundation, Inc. | Histone deacetylase inhibitors and compositions and methods of use thereof |
| WO2017211650A1 (en) * | 2016-06-09 | 2017-12-14 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
| WO2018015447A1 (en) * | 2016-07-22 | 2018-01-25 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| US10357493B2 (en) | 2017-03-10 | 2019-07-23 | Selenity Therapeutics (Bermuda), Ltd. | Metalloenzyme inhibitor compounds |
| WO2019219464A1 (en) | 2018-05-15 | 2019-11-21 | Basf Se | Substituted trifluoromethyloxadiazoles for combating phytopathogenic fungi |
| KR102009034B1 (ko) | 2019-01-31 | 2019-08-08 | 주식회사 아이스크림에듀 | 학습 분석을 기초로 정보를 제공하는 방법 및 시스템 |
| KR102052844B1 (ko) | 2019-01-31 | 2019-12-05 | 주식회사 아이스크림에듀 | 학습 분석 방법 및 시스템 |
| CN114727974A (zh) | 2019-07-30 | 2022-07-08 | 艾科尼佐治疗股份有限公司 | Hdac6抑制剂及其用途 |
| KR102232343B1 (ko) | 2019-12-11 | 2021-03-26 | 주식회사 아이스크림에듀 | 인공지능 기반 맞춤형 학습 방법 및 시스템 |
| KR102191671B1 (ko) | 2019-12-20 | 2020-12-16 | 주식회사 아이스크림에듀 | 소셜 러닝 및 e포트폴리오 기반 맞춤형 학습 방법 및 시스템 |
| KR102191672B1 (ko) | 2019-12-20 | 2020-12-16 | 주식회사 아이스크림에듀 | 학습 분석 및 인공지능 기반 맞춤형 학습 방법 및 시스템 |
| KR102191670B1 (ko) | 2019-12-20 | 2020-12-16 | 주식회사 아이스크림에듀 | 문제은행 및 지식맵 기반 맞춤형 학습 방법 및 시스템 |
| KR102197752B1 (ko) | 2019-12-20 | 2021-01-04 | 주식회사 아이스크림에듀 | 맞춤형 자동 문항 생성을 통한 인공지능 기반 학습 방법 및 시스템 |
| KR102232344B1 (ko) | 2020-02-27 | 2021-03-26 | 주식회사 아이스크림에듀 | 빅데이터 및 인공지능 기반의 맞춤형 학습 방법 및 시스템 |
| KR102258234B1 (ko) | 2020-02-27 | 2021-05-31 | 주식회사 아이스크림에듀 | 인공지능 가정교사 인터페이스가 적용된 맞춤형 학습 방법 및 시스템 |
| KR102258235B1 (ko) | 2020-02-27 | 2021-05-31 | 주식회사 아이스크림에듀 | 실감 콘텐츠가 적용된 인공지능 기반의 맞춤형 학습 방법 및 시스템 |
| CN111190006A (zh) * | 2020-03-09 | 2020-05-22 | 上海市东方医院（同济大学附属东方医院） | 组蛋白去乙酰化酶6在制备用于评估维持性腹膜透析患者腹膜功能的标志物中的用途 |
| KR102222533B1 (ko) | 2020-06-25 | 2021-03-05 | 주식회사 아이스크림미디어 | 고정형 웹 콘텐츠를 반응형 콘텐츠로 자동 변환하는 시스템 및 그 제어방법 |
| CA3189738A1 (en) * | 2020-08-07 | 2022-02-10 | Italfarmaco S.P.A. | Novel oxadiazole-based selective hdac6 inhibitors |
| KR102248960B1 (ko) | 2020-08-19 | 2021-05-07 | 주식회사 아이스크림에듀 | 인공지능 학습 플랫폼을 이용한 비즈니스 방법 및 시스템 |
| WO2022169985A1 (en) | 2021-02-03 | 2022-08-11 | Eikonizo Therapeutics, Inc. | Hdac6 inhibitors and uses thereof |
| AU2023250964A1 (en) | 2022-04-08 | 2024-11-07 | Eikonizo Therapeutics, Inc. | Oxadiazole hdac6 inhibitors and uses thereof |
| CN117430513A (zh) * | 2023-10-27 | 2024-01-23 | 中昊(大连)化工研究设计院有限公司 | 环丙基胺的合成新方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006061638A2 (en) | 2004-12-10 | 2006-06-15 | Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa | Heterocycle derivatives as histone deacetylase (hdac) inhibitors |
| GB0427138D0 (en) * | 2004-12-10 | 2005-01-12 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
| KR101781663B1 (ko) | 2010-01-13 | 2017-09-25 | 템페로 파마슈티칼즈, 인크. | 히스톤 데아세틸라제 효소를 억제하기 위한 화합물 및 이를 제조하는 방법 |
| EP2523664A4 (en) * | 2010-01-13 | 2013-06-26 | Tempero Pharmaceuticals Inc | COMPOUNDS AND METHODS |
| WO2013006408A1 (en) * | 2011-07-01 | 2013-01-10 | Tempero Pharmaceuticals, Inc. | Compounds and methods |
| EA201490228A1 (ru) * | 2011-07-08 | 2014-08-29 | Новартис Аг | Новые производные трифторметилоксадиазола и их применение для лечения заболевания |
| WO2013009810A1 (en) | 2011-07-13 | 2013-01-17 | Tempero Pharmaceuticals, Inc. | Methods of treatment |
| WO2013009830A1 (en) * | 2011-07-13 | 2013-01-17 | Tempero Pharmaceuticals, Inc. | Methods of treatment |
| SG2014012926A (en) | 2011-08-30 | 2014-06-27 | Chdi Foundation Inc | Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
| CA2856334A1 (en) * | 2011-11-28 | 2013-06-06 | Christina Hebach | Novel trifluoromethyl-oxadiazole derivatives and their use in the treatment of disease |
| JP6275690B2 (ja) * | 2012-04-05 | 2018-02-07 | シーエイチディーアイ ファウンデーション，インコーポレーテッド | キヌレニン−３−モノオキシゲナーゼインヒビターおよびその医薬組成物ならびにこれらの使用方法 |
| EA035592B1 (ru) * | 2015-05-07 | 2020-07-13 | Сиэйчдиай Фаундэйшн, Инк. | Ингибиторы деацетилаз гистонов и композиции и способы их применения |
| CA2984618C (en) | 2015-05-07 | 2024-01-09 | Chdi Foundation, Inc. | Histone deacetylase inhibitors and compositions and methods of use thereof |
| BR112017027798B1 (pt) | 2015-07-27 | 2023-12-19 | Chong Kun Dang Pharmaceutical Corp | Compostos de derivado de 1,3,4-oxadiazol sulfamida como inibidor de histona desacetilase 6 e a composição farmacêutica que compreende os mesmos |
| HRP20230052T1 (hr) | 2015-07-27 | 2023-03-03 | Chong Kun Dang Pharmaceutical Corp. | Spojevi derivata 1,3,4-oksadiazol sulfonamida kao inhibitori histonske deacetilaze 6, i farmaceutski pripravak koji ih sadrži |
| HRP20220003T1 (hr) | 2015-08-04 | 2022-04-01 | Chong Kun Dang Pharmaceutical Corp. | Spojevi derivata 1,3,4-oksadiazola kao inhibitori histonske deacetilaze 6, i farmaceutski pripravak koji ih sadrži |
-
2016
- 2016-05-06 EA EA201792255A patent/EA035592B1/ru not_active IP Right Cessation
- 2016-05-06 BR BR112017023710-5A patent/BR112017023710B1/pt active IP Right Grant
- 2016-05-06 AU AU2016256917A patent/AU2016256917B2/en active Active
- 2016-05-06 MX MX2017014299A patent/MX379817B/es unknown
- 2016-05-06 US US15/148,884 patent/US10047073B2/en active Active
- 2016-05-06 JP JP2017557413A patent/JP6782255B2/ja not_active Expired - Fee Related
- 2016-05-06 EP EP16790199.0A patent/EP3291809B1/en active Active
- 2016-05-06 KR KR1020177034473A patent/KR20180002730A/ko not_active Withdrawn
- 2016-05-06 CA CA2984621A patent/CA2984621C/en active Active
- 2016-05-06 CN CN201680040059.0A patent/CN107735087B/zh active Active
- 2016-05-06 WO PCT/US2016/031329 patent/WO2016179550A1/en not_active Ceased
-
2017
- 2017-11-06 IL IL255449A patent/IL255449B2/en unknown
-
2018
- 2018-07-26 US US16/046,268 patent/US20190185463A1/en not_active Abandoned
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