MX379817B - Inhibidores de histona deacetilasa y composiciones y metodos para el uso de los mismos. - Google Patents
Inhibidores de histona deacetilasa y composiciones y metodos para el uso de los mismos.Info
- Publication number
- MX379817B MX379817B MX2017014299A MX2017014299A MX379817B MX 379817 B MX379817 B MX 379817B MX 2017014299 A MX2017014299 A MX 2017014299A MX 2017014299 A MX2017014299 A MX 2017014299A MX 379817 B MX379817 B MX 379817B
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- methods
- histone deacetylase
- deacetylase inhibitors
- inhibitors
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 229940121372 histone deacetylase inhibitor Drugs 0.000 title 1
- 239000003276 histone deacetylase inhibitor Substances 0.000 title 1
- 102000003964 Histone deacetylase Human genes 0.000 abstract 2
- 108090000353 Histone deacetylase Proteins 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562158379P | 2015-05-07 | 2015-05-07 | |
| PCT/US2016/031329 WO2016179550A1 (en) | 2015-05-07 | 2016-05-06 | Histone deacetylase inhibitors and compositions and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017014299A MX2017014299A (es) | 2018-08-09 |
| MX379817B true MX379817B (es) | 2025-03-11 |
Family
ID=57218066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017014299A MX379817B (es) | 2015-05-07 | 2016-05-06 | Inhibidores de histona deacetilasa y composiciones y metodos para el uso de los mismos. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10047073B2 (enExample) |
| EP (1) | EP3291809B1 (enExample) |
| JP (1) | JP6782255B2 (enExample) |
| KR (1) | KR20180002730A (enExample) |
| CN (1) | CN107735087B (enExample) |
| AU (1) | AU2016256917B2 (enExample) |
| BR (1) | BR112017023710B1 (enExample) |
| CA (1) | CA2984621C (enExample) |
| EA (1) | EA035592B1 (enExample) |
| IL (1) | IL255449B2 (enExample) |
| MX (1) | MX379817B (enExample) |
| WO (1) | WO2016179550A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA035592B1 (ru) * | 2015-05-07 | 2020-07-13 | Сиэйчдиай Фаундэйшн, Инк. | Ингибиторы деацетилаз гистонов и композиции и способы их применения |
| CA2984618C (en) | 2015-05-07 | 2024-01-09 | Chdi Foundation, Inc. | Histone deacetylase inhibitors and compositions and methods of use thereof |
| WO2017211650A1 (en) * | 2016-06-09 | 2017-12-14 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
| WO2018015447A1 (en) * | 2016-07-22 | 2018-01-25 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| US10357493B2 (en) | 2017-03-10 | 2019-07-23 | Selenity Therapeutics (Bermuda), Ltd. | Metalloenzyme inhibitor compounds |
| WO2019219464A1 (en) | 2018-05-15 | 2019-11-21 | Basf Se | Substituted trifluoromethyloxadiazoles for combating phytopathogenic fungi |
| KR102009034B1 (ko) | 2019-01-31 | 2019-08-08 | 주식회사 아이스크림에듀 | 학습 분석을 기초로 정보를 제공하는 방법 및 시스템 |
| KR102052844B1 (ko) | 2019-01-31 | 2019-12-05 | 주식회사 아이스크림에듀 | 학습 분석 방법 및 시스템 |
| CN114727974A (zh) | 2019-07-30 | 2022-07-08 | 艾科尼佐治疗股份有限公司 | Hdac6抑制剂及其用途 |
| KR102232343B1 (ko) | 2019-12-11 | 2021-03-26 | 주식회사 아이스크림에듀 | 인공지능 기반 맞춤형 학습 방법 및 시스템 |
| KR102191671B1 (ko) | 2019-12-20 | 2020-12-16 | 주식회사 아이스크림에듀 | 소셜 러닝 및 e포트폴리오 기반 맞춤형 학습 방법 및 시스템 |
| KR102191672B1 (ko) | 2019-12-20 | 2020-12-16 | 주식회사 아이스크림에듀 | 학습 분석 및 인공지능 기반 맞춤형 학습 방법 및 시스템 |
| KR102191670B1 (ko) | 2019-12-20 | 2020-12-16 | 주식회사 아이스크림에듀 | 문제은행 및 지식맵 기반 맞춤형 학습 방법 및 시스템 |
| KR102197752B1 (ko) | 2019-12-20 | 2021-01-04 | 주식회사 아이스크림에듀 | 맞춤형 자동 문항 생성을 통한 인공지능 기반 학습 방법 및 시스템 |
| KR102232344B1 (ko) | 2020-02-27 | 2021-03-26 | 주식회사 아이스크림에듀 | 빅데이터 및 인공지능 기반의 맞춤형 학습 방법 및 시스템 |
| KR102258234B1 (ko) | 2020-02-27 | 2021-05-31 | 주식회사 아이스크림에듀 | 인공지능 가정교사 인터페이스가 적용된 맞춤형 학습 방법 및 시스템 |
| KR102258235B1 (ko) | 2020-02-27 | 2021-05-31 | 주식회사 아이스크림에듀 | 실감 콘텐츠가 적용된 인공지능 기반의 맞춤형 학습 방법 및 시스템 |
| CN111190006A (zh) * | 2020-03-09 | 2020-05-22 | 上海市东方医院（同济大学附属东方医院） | 组蛋白去乙酰化酶6在制备用于评估维持性腹膜透析患者腹膜功能的标志物中的用途 |
| KR102222533B1 (ko) | 2020-06-25 | 2021-03-05 | 주식회사 아이스크림미디어 | 고정형 웹 콘텐츠를 반응형 콘텐츠로 자동 변환하는 시스템 및 그 제어방법 |
| CA3189738A1 (en) * | 2020-08-07 | 2022-02-10 | Italfarmaco S.P.A. | Novel oxadiazole-based selective hdac6 inhibitors |
| KR102248960B1 (ko) | 2020-08-19 | 2021-05-07 | 주식회사 아이스크림에듀 | 인공지능 학습 플랫폼을 이용한 비즈니스 방법 및 시스템 |
| WO2022169985A1 (en) | 2021-02-03 | 2022-08-11 | Eikonizo Therapeutics, Inc. | Hdac6 inhibitors and uses thereof |
| AU2023250964A1 (en) | 2022-04-08 | 2024-11-07 | Eikonizo Therapeutics, Inc. | Oxadiazole hdac6 inhibitors and uses thereof |
| CN117430513A (zh) * | 2023-10-27 | 2024-01-23 | 中昊(大连)化工研究设计院有限公司 | 环丙基胺的合成新方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006061638A2 (en) | 2004-12-10 | 2006-06-15 | Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa | Heterocycle derivatives as histone deacetylase (hdac) inhibitors |
| GB0427138D0 (en) * | 2004-12-10 | 2005-01-12 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
| KR101781663B1 (ko) | 2010-01-13 | 2017-09-25 | 템페로 파마슈티칼즈, 인크. | 히스톤 데아세틸라제 효소를 억제하기 위한 화합물 및 이를 제조하는 방법 |
| EP2523664A4 (en) * | 2010-01-13 | 2013-06-26 | Tempero Pharmaceuticals Inc | COMPOUNDS AND METHODS |
| WO2013006408A1 (en) * | 2011-07-01 | 2013-01-10 | Tempero Pharmaceuticals, Inc. | Compounds and methods |
| EA201490228A1 (ru) * | 2011-07-08 | 2014-08-29 | Новартис Аг | Новые производные трифторметилоксадиазола и их применение для лечения заболевания |
| WO2013009810A1 (en) | 2011-07-13 | 2013-01-17 | Tempero Pharmaceuticals, Inc. | Methods of treatment |
| WO2013009830A1 (en) * | 2011-07-13 | 2013-01-17 | Tempero Pharmaceuticals, Inc. | Methods of treatment |
| SG2014012926A (en) | 2011-08-30 | 2014-06-27 | Chdi Foundation Inc | Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
| CA2856334A1 (en) * | 2011-11-28 | 2013-06-06 | Christina Hebach | Novel trifluoromethyl-oxadiazole derivatives and their use in the treatment of disease |
| JP6275690B2 (ja) * | 2012-04-05 | 2018-02-07 | シーエイチディーアイ ファウンデーション，インコーポレーテッド | キヌレニン−３−モノオキシゲナーゼインヒビターおよびその医薬組成物ならびにこれらの使用方法 |
| EA035592B1 (ru) * | 2015-05-07 | 2020-07-13 | Сиэйчдиай Фаундэйшн, Инк. | Ингибиторы деацетилаз гистонов и композиции и способы их применения |
| CA2984618C (en) | 2015-05-07 | 2024-01-09 | Chdi Foundation, Inc. | Histone deacetylase inhibitors and compositions and methods of use thereof |
| BR112017027798B1 (pt) | 2015-07-27 | 2023-12-19 | Chong Kun Dang Pharmaceutical Corp | Compostos de derivado de 1,3,4-oxadiazol sulfamida como inibidor de histona desacetilase 6 e a composição farmacêutica que compreende os mesmos |
| HRP20230052T1 (hr) | 2015-07-27 | 2023-03-03 | Chong Kun Dang Pharmaceutical Corp. | Spojevi derivata 1,3,4-oksadiazol sulfonamida kao inhibitori histonske deacetilaze 6, i farmaceutski pripravak koji ih sadrži |
| HRP20220003T1 (hr) | 2015-08-04 | 2022-04-01 | Chong Kun Dang Pharmaceutical Corp. | Spojevi derivata 1,3,4-oksadiazola kao inhibitori histonske deacetilaze 6, i farmaceutski pripravak koji ih sadrži |
-
2016
- 2016-05-06 EA EA201792255A patent/EA035592B1/ru not_active IP Right Cessation
- 2016-05-06 BR BR112017023710-5A patent/BR112017023710B1/pt active IP Right Grant
- 2016-05-06 AU AU2016256917A patent/AU2016256917B2/en active Active
- 2016-05-06 MX MX2017014299A patent/MX379817B/es unknown
- 2016-05-06 US US15/148,884 patent/US10047073B2/en active Active
- 2016-05-06 JP JP2017557413A patent/JP6782255B2/ja not_active Expired - Fee Related
- 2016-05-06 EP EP16790199.0A patent/EP3291809B1/en active Active
- 2016-05-06 KR KR1020177034473A patent/KR20180002730A/ko not_active Withdrawn
- 2016-05-06 CA CA2984621A patent/CA2984621C/en active Active
- 2016-05-06 CN CN201680040059.0A patent/CN107735087B/zh active Active
- 2016-05-06 WO PCT/US2016/031329 patent/WO2016179550A1/en not_active Ceased
-
2017
- 2017-11-06 IL IL255449A patent/IL255449B2/en unknown
-
2018
- 2018-07-26 US US16/046,268 patent/US20190185463A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BR112017023710A2 (pt) | 2018-07-31 |
| MX2017014299A (es) | 2018-08-09 |
| CN107735087A (zh) | 2018-02-23 |
| EP3291809A4 (en) | 2018-10-03 |
| EP3291809A1 (en) | 2018-03-14 |
| KR20180002730A (ko) | 2018-01-08 |
| US20190185463A1 (en) | 2019-06-20 |
| EA201792255A1 (ru) | 2018-06-29 |
| AU2016256917B2 (en) | 2021-08-26 |
| US10047073B2 (en) | 2018-08-14 |
| WO2016179550A1 (en) | 2016-11-10 |
| CN107735087B (zh) | 2021-09-03 |
| JP2018515492A (ja) | 2018-06-14 |
| CA2984621C (en) | 2023-09-26 |
| IL255449A0 (en) | 2017-12-31 |
| EA035592B1 (ru) | 2020-07-13 |
| IL255449B2 (en) | 2023-07-01 |
| IL255449B1 (en) | 2023-03-01 |
| AU2016256917A1 (en) | 2017-11-23 |
| HK1252489A1 (zh) | 2019-05-24 |
| EP3291809B1 (en) | 2021-08-25 |
| CA2984621A1 (en) | 2016-11-10 |
| JP6782255B2 (ja) | 2020-11-11 |
| BR112017023710B1 (pt) | 2023-03-07 |
| US20160333001A1 (en) | 2016-11-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2017014299A (es) | Inhibidores de histona deacetilasa y composiciones y metodos para el uso de los mismos. | |
| MX378983B (es) | Inhibidores de histona deacetilasa y composiciones y metodos para el uso de los mismos. | |
| CO2018005381A2 (es) | Inhibidores éster de acc y usos de los mismos | |
| CL2017000576A1 (es) | Inhibidores de mk2 y sus usos | |
| CO2018004124A2 (es) | Compuestos heterocíclicos | |
| DK3442973T3 (da) | Hidtil ukendte forbindelser som autotaxinhæmmere og farmaceutiske sammensætninger omfattende samme | |
| CO2017002532A2 (es) | Indazoles sustituidos con bencilo como inhibidores de bub1 | |
| CU20180001A7 (es) | Derivados de oxopiridina sustituidos y procesos para su preparación | |
| MX2019012434A (es) | Agentes inductores de apoptosis. | |
| EA201890749A1 (ru) | ИНГИБИТОРЫ АЦЕТИЛ-КоА-КАРБОКСИЛАЗЫ (ACC) И ИХ ПРИМЕНЕНИЕ | |
| MX2016015565A (es) | Ciertos inhibidores de la proteina quinasa. | |
| HUE057041T2 (hu) | Hiszton deacetiláz hetero-halogén gátlói | |
| CR20180072A (es) | Nuevos compuestos biciclicos como inhibidores de atx | |
| EP3624804A4 (en) | HISTONE DEACETYLASE INHIBITORS (HDAC) | |
| MX2017013875A (es) | Ciertos inhibidores de la proteína quinasa. | |
| HK1220407A1 (zh) | 组蛋白去乙酰酶抑制剂，其组合物及其使用方法 | |
| CL2017001923A1 (es) | Derivados de 9h-pirrolo-dipiridina | |
| CL2016003074A1 (es) | Compuestos derivados de 2-oxi-2-fenil-n-5-pirrolidin-3-ilamino-1,3,4-tiadiazol-2-ilacetamida, inhibidores gls1 composición farmacéutica y su uso para tratar el cáncer. | |
| EA201590028A1 (ru) | Ингибиторы гистондеацетилазы и их композиции и способы их применения | |
| DK3653620T3 (da) | Nye heteroarylamid-derivater som selektive inhibitorer af histondeacetylaser 1 og 2 (HDAC1-2) | |
| BR112017026682A2 (pt) | novos compostos bicíclicos como inibidores de dupla ação de atx/ca | |
| DOP2018000066A (es) | Compuestos útiles para inhibir ror-gamma-t | |
| HK1220406A1 (zh) | 组蛋白去乙酰酶抑制剂及组合物 | |
| EP3820859C0 (en) | HISTONE DEACETYLASE INHIBITORS | |
| DK3362450T3 (da) | N1- og N7-substituerede sibirilin-derivater og anvendelse deraf som inhibitorer af cellulær nekroptose |