|
US9512194B2
(en)
|
2012-01-27 |
2016-12-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
Modified IL-13 polypeptides
|
|
IN2015KN00329A
(enExample)
|
2012-08-09 |
2015-07-10 |
Univ Leland Stanford Junior |
|
|
SG11201505858VA
(en)
|
2013-01-28 |
2015-09-29 |
St Jude Childrens Res Hospital |
A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease
|
|
JP6936934B2
(ja)
|
2013-09-24 |
2021-09-22 |
メディシナ セラピューティクス インコーポレイテッド |
インターロイキン−４受容体結合融合タンパク質及びその使用
|
|
KR102308597B1
(ko)
*
|
2013-10-17 |
2021-10-01 |
내셔널 유니버시티 오브 싱가포르 |
다중 종양에 대항하여 항체-의존성 세포 세포독성을 촉발시키는 키메라 수용체
|
|
US10144770B2
(en)
|
2013-10-17 |
2018-12-04 |
National University Of Singapore |
Chimeric receptors and uses thereof in immune therapy
|
|
EP3805371A1
(en)
|
2014-05-15 |
2021-04-14 |
National University of Singapore |
Modified natural killer cells and uses thereof
|
|
US20170151281A1
(en)
|
2015-02-19 |
2017-06-01 |
Batu Biologics, Inc. |
Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
|
|
EP3770168A1
(en)
|
2015-05-18 |
2021-01-27 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
EP3430036A4
(en)
*
|
2016-03-18 |
2019-08-14 |
Unum Therapeutics |
MODIFIED CHIMERIC RECEPTORS AND USES IN IMMUNOTHERAPY
|
|
WO2017205254A1
(en)
*
|
2016-05-23 |
2017-11-30 |
Unum Therapeutics |
Immune cells expressing antibody-coupled t-cell receptor (actr) for use in inhibiting cancer cells expressing surface immunoglobulin
|
|
WO2018017649A1
(en)
*
|
2016-07-19 |
2018-01-25 |
Unum Therapeutics Inc. |
Use of antibody-coupled t cell receptor (actr) with multiple anti-cancer antibodies in cancer treatment
|
|
WO2018026953A1
(en)
|
2016-08-02 |
2018-02-08 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
BR112019007100A2
(pt)
|
2016-10-07 |
2019-06-25 |
Tcr2 Therapeutics Inc |
composições e métodos para reprogramação de receptores de célula t com o uso de proteínas de fusão
|
|
CN110177803A
(zh)
|
2016-11-22 |
2019-08-27 |
T细胞受体治疗公司 |
用于使用融合蛋白进行tcr重新编程的组合物和方法
|
|
CN110352068A
(zh)
|
2016-12-02 |
2019-10-18 |
南加利福尼亚大学 |
合成的免疫受体及其使用方法
|
|
US20200095301A1
(en)
*
|
2016-12-14 |
2020-03-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Il-13 superkine: immune cell targeting constructs and methods of use thereof
|
|
US11578115B2
(en)
|
2017-01-10 |
2023-02-14 |
The General Hospital Corporation |
Chimeric antigen receptors based on alternative signal 1 domains
|
|
CN110494162A
(zh)
*
|
2017-01-30 |
2019-11-22 |
优努姆治疗公司 |
改良的抗体-偶联t细胞受体构建体及其治疗用途
|
|
AU2018222741A1
(en)
*
|
2017-02-17 |
2019-09-26 |
Unum Therapeutics Inc. |
Co-use of anti-BCMA antibody and antibody-coupled T celll receptor (ACTR) in cancer therapy and B cell disorders
|
|
EP3595721B1
(en)
|
2017-03-16 |
2025-07-09 |
The General Hospital Corporation |
Chimeric antigen receptors targeting cd37
|
|
CA3056837A1
(en)
*
|
2017-03-27 |
2018-10-04 |
F. Hoffmann-La Roche Ag |
Improved antigen binding receptors
|
|
CN117363636A
(zh)
|
2017-03-27 |
2024-01-09 |
新加坡国立大学 |
一种编码嵌合受体的多核苷酸
|
|
SG11201908784TA
(en)
*
|
2017-03-27 |
2019-10-30 |
Hoffmann La Roche |
Improved antigen binding receptor formats
|
|
MX2019011570A
(es)
|
2017-03-27 |
2019-11-18 |
Nat Univ Singapore |
Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.
|
|
MA50865A
(fr)
|
2017-06-07 |
2020-04-15 |
Seattle Genetics Inc |
Lymphocytes t à fucosylation de surface réduite et procédés de production et d'utilisation de ceux-ci
|
|
KR20200041377A
(ko)
*
|
2017-09-06 |
2020-04-21 |
프레드 헛친슨 켄서 리서치 센터 |
Strep-tag 특이적 결합 단백질 및 그 용도
|
|
CA3078434A1
(en)
|
2017-10-10 |
2019-04-18 |
Medicenna Therapeutics, Inc. |
Il-4-fusion formulations for treatment of central nervous system (cns) tumors
|
|
US20200283501A1
(en)
*
|
2017-10-26 |
2020-09-10 |
Regents Of The University Of Minnesota |
Recombinant immune cells, methods of making, and methods of use
|
|
EP3703689A1
(en)
*
|
2017-11-01 |
2020-09-09 |
Allogene Therapeutics, Inc. |
Modified caspase-9 polypeptides and methods of use thereof
|
|
WO2019094725A2
(en)
*
|
2017-11-09 |
2019-05-16 |
Sangamo Therapeutics, Inc. |
Genetic modification of cytokine inducible sh2-containing protein (cish) gene
|
|
KR102802061B1
(ko)
*
|
2017-11-10 |
2025-05-02 |
주라 바이오, 인크. |
주 조직적합성 복합체-기반 키메라 수용체 및 자가면역 질병을 치료하기 위한 이의 용도
|
|
US11802163B2
(en)
|
2017-11-10 |
2023-10-31 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptors targeting glypican-3 or mesothelin
|
|
CA3086045A1
(en)
|
2017-12-19 |
2019-06-27 |
Akouos, Inc. |
Aav-mediated delivery of therapeutic antibodies to the inner ear
|
|
CN109970864A
(zh)
*
|
2017-12-28 |
2019-07-05 |
上海细胞治疗研究院 |
一种双向激活共刺激分子受体及其用途
|
|
CA3087331A1
(en)
*
|
2017-12-29 |
2019-07-04 |
City Of Hope |
Meditope-enabled t cells
|
|
JP7360174B2
(ja)
|
2018-02-09 |
2023-10-12 |
ナショナル ユニヴァーシティー オブ シンガポール |
ナチュラルキラー細胞免疫療法における活性化キメラ受容体及びその使用
|
|
WO2019179871A1
(en)
*
|
2018-03-19 |
2019-09-26 |
Svar Life Science Ab |
SYSTEM AND PRODUCTS FOR IMPROVED QUANTIFICATION OF ADCC and ADCP ACTIVITY
|
|
US12441787B2
(en)
|
2018-04-02 |
2025-10-14 |
National University Of Singapore |
Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells
|
|
IL321548A
(en)
*
|
2018-05-22 |
2025-08-01 |
Immunitybio Inc |
Recombinant NK cells expressing a chimeric antigen receptor (CAR) for epsilon-FC and uses thereof
|
|
WO2019232523A1
(en)
|
2018-06-01 |
2019-12-05 |
The Board Of Trustees Of The Leland Stanford Junior University |
Il-13/il-4 superkines: immune cell targeting constructs and methods of use thereof
|
|
WO2020010110A1
(en)
|
2018-07-03 |
2020-01-09 |
Unum Therapeutics Inc. |
Chimeric receptors in combination with trans metabolism molecules enhancing glucose import and therapeutic uses thereof
|
|
WO2020037066A1
(en)
|
2018-08-14 |
2020-02-20 |
Unum Therapeutics Inc. |
Chimeric antigen receptor polypeptides in combination with trans metabolism molecules modulating krebs cycle and therapeutic uses thereof
|
|
WO2020044239A1
(en)
|
2018-08-29 |
2020-03-05 |
National University Of Singapore |
A method to specifically stimulate survival and expansion of genetically-modified immune cells
|
|
WO2020068702A1
(en)
*
|
2018-09-24 |
2020-04-02 |
Fred Hutchinson Cancer Research Center |
Chimeric receptor proteins and uses thereof
|
|
EP3876977A1
(en)
|
2018-11-06 |
2021-09-15 |
The Regents Of The University Of California |
Chimeric antigen receptors for phagocytosis
|
|
CN113226340A
(zh)
|
2018-11-26 |
2021-08-06 |
恩卡尔塔公司 |
同时扩增多种免疫细胞类型的方法、相关组合物及其在癌症免疫疗法中的用途
|
|
KR20210137085A
(ko)
|
2019-03-05 |
2021-11-17 |
엔카르타, 인크. |
Cd19 유도된 키메라 항원 수용체 및 면역 요법에서 이의 용도
|
|
AU2020243623A1
(en)
*
|
2019-03-19 |
2021-11-04 |
Ramot At Tel-Aviv University Ltd. |
T cell expressing an FC gamma receptor and methods of use thereof
|
|
JPWO2020213724A1
(enExample)
|
2019-04-19 |
2020-10-22 |
|
|
|
US11026973B2
(en)
|
2019-04-30 |
2021-06-08 |
Myeloid Therapeutics, Inc. |
Engineered phagocytic receptor compositions and methods of use thereof
|
|
CN110592014A
(zh)
*
|
2019-08-14 |
2019-12-20 |
广东美赛尔细胞生物科技有限公司 |
一种在nk细胞治疗中免辐照体外体内持续去除饲养细胞的方法
|
|
WO2021046243A2
(en)
|
2019-09-03 |
2021-03-11 |
Myeloid Therapeutics, Inc. |
Methods and compositions for genomic integration
|
|
CN111944062B
(zh)
|
2019-12-09 |
2023-11-07 |
深圳市体内生物医药科技有限公司 |
一种识别Fc片段的嵌合抗原受体及其应用
|
|
US10980836B1
(en)
|
2019-12-11 |
2021-04-20 |
Myeloid Therapeutics, Inc. |
Therapeutic cell compositions and methods of manufacturing and use thereof
|
|
CN111100942B
(zh)
*
|
2019-12-31 |
2023-03-28 |
海南波莲水稻基因科技有限公司 |
与水稻光温敏核雄性不育表型相关的分子标记和应用
|
|
CN113248620A
(zh)
*
|
2020-02-13 |
2021-08-13 |
四川大学 |
一种嵌合抗原受体的共刺激信号结构域及其应用
|
|
EP3875478A1
(en)
*
|
2020-03-05 |
2021-09-08 |
Canvax Biotech, S.L. |
Novel non-immunogenic chimeric antigen receptors and uses thereof
|
|
WO2021260696A1
(en)
|
2020-06-22 |
2021-12-30 |
Ramot At Tel-Aviv University Ltd. |
Multi subunit protein modules, cells expressing same and uses thereof
|
|
CN113583139A
(zh)
*
|
2020-07-06 |
2021-11-02 |
上海鑫湾生物科技有限公司 |
一种嵌合受体及其应用
|
|
TW202220677A
(zh)
|
2020-07-31 |
2022-06-01 |
日商中外製藥股份有限公司 |
含有表現嵌合受體之細胞的醫藥組成物
|
|
US20230302132A1
(en)
*
|
2020-08-14 |
2023-09-28 |
Shanghai Xinghua Bio Pharmaceutical Science & Technology Co., Ltd |
Method for preparing universal immune cells and use thereof
|
|
CN111876382A
(zh)
*
|
2020-08-14 |
2020-11-03 |
上海星华生物医药科技有限公司 |
一种制备通用型免疫细胞的方法及其应用
|
|
KR20230052279A
(ko)
*
|
2020-08-19 |
2023-04-19 |
아스테라스 세이야쿠 가부시키가이샤 |
비-천연 발생 변형 fc 수용체에 특이적으로 결합하는 igg의 인간 비-천연 발생 변형 fc 영역
|
|
US12702710B2
(en)
|
2020-10-12 |
2026-08-11 |
Medicenna Therapeutics Inc. |
Combination therapy of MDNA55 and a vascular endothelial growth factor a (VEGF-A)
|
|
EP4240367A4
(en)
|
2020-11-04 |
2024-10-16 |
Myeloid Therapeutics, Inc. |
MODIFIED CHIMERIC FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF
|
|
IL303317A
(en)
|
2020-12-01 |
2023-07-01 |
Akouos Inc |
ANTI-NATURAL ANTIBODY STRUCTURES AND RELATED METHODS FOR THE TREATMENT OF SYMPTOMS ASSOCIATED WITH VESTIBULAR SWANNOMA
|
|
AU2021409653B2
(en)
*
|
2020-12-22 |
2026-03-12 |
Immunitybio, Inc. |
Fc-receptor car constructs and cells
|
|
WO2022150379A1
(en)
*
|
2021-01-08 |
2022-07-14 |
Regents Of The University Of Minnesota |
Nk cell engager molecules and methods of use
|
|
KR20240013094A
(ko)
|
2021-03-17 |
2024-01-30 |
마이얼로이드 테라퓨틱스, 인크. |
조작된 키메라 융합 단백질 조성물 및 그의 사용 방법
|
|
WO2022241029A1
(en)
|
2021-05-11 |
2022-11-17 |
Myeloid Therapeutics, Inc. |
Methods and compositions for genomic integration
|
|
MX2024004009A
(es)
|
2021-09-27 |
2024-06-19 |
Sotio Biotech Inc |
Polipéptidos receptores quiméricos en combinación con moléculas transmetabólicas que redirigen metabolitos de glucosa fuera de la vía de la glucólisis y usos terapéuticos de estos.
|
|
CA3237201A1
(en)
|
2021-11-16 |
2023-05-25 |
Sotio Biotech Inc. |
Treatment of myxoid/round cell liposarcoma patients
|
|
CN115806618B
(zh)
*
|
2022-03-30 |
2025-11-11 |
河北森朗生物科技有限公司 |
一种抗cd7的纳米抗体vhh12及其相关产品、方法和用途
|
|
US20260053924A1
(en)
|
2022-08-19 |
2026-02-26 |
Sotio Biotech Inc. |
Genetically engineered immune cells with chimeric receptor polypeptides in combination with multiple trans metabolism molecules and therapeutic uses thereof
|
|
WO2024040207A1
(en)
|
2022-08-19 |
2024-02-22 |
Sotio Biotech Inc. |
Genetically engineered natural killer (nk) cells with chimeric receptor polypeptides in combination with trans metabolism molecules and therapeutic uses thereof
|
|
WO2024102954A1
(en)
*
|
2022-11-10 |
2024-05-16 |
Massachusetts Institute Of Technology |
Activation induced clipping system (aics)
|
|
EP4694916A1
(en)
|
2023-04-14 |
2026-02-18 |
SOTIO Biotech Inc. |
Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists
|
|
WO2024215987A1
(en)
|
2023-04-14 |
2024-10-17 |
Sotio Biotech Inc. |
IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES
|
|
KR20260024373A
(ko)
*
|
2023-05-05 |
2026-02-20 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
다중-수용체 자연 살해 세포
|
|
KR20260113096A
(ko)
*
|
2023-11-16 |
2026-07-21 |
리포진 메디슨 |
키메라 항원 수용체 및 그 용도
|
|
KR102764613B1
(ko)
*
|
2024-03-28 |
2025-02-12 |
한양대학교 에리카산학협력단 |
NaPi2b 특이적 CAR-T를 포함하는 난소암 치료용 약학 조성물
|
|
WO2025235862A1
(en)
*
|
2024-05-10 |
2025-11-13 |
Inndura Therapeutics Inc. |
A modified immune cell receptor comprising a target-binding domain and the extracellular domain of cd16a
|
|
WO2026077463A1
(zh)
*
|
2024-10-12 |
2026-04-16 |
深圳市济因生物科技有限公司 |
一种嵌合蛋白和工程化免疫细胞及其制备方法与应用
|