|
EP2850093B1
(en)
|
2012-01-27 |
2019-01-09 |
The Board of Trustees of the Leland Stanford Junior University |
Therapeutic il-13 polypeptides
|
|
IN2015KN00329A
(enExample)
|
2012-08-09 |
2015-07-10 |
Univ Leland Stanford Junior |
|
|
WO2014117121A1
(en)
|
2013-01-28 |
2014-07-31 |
St. Jude Children's Research Hospital, Inc. |
A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease
|
|
CN105764926A
(zh)
|
2013-09-24 |
2016-07-13 |
梅迪塞纳医疗股份有限公司 |
白介素-4受体结合融合蛋白及其应用
|
|
US10144770B2
(en)
|
2013-10-17 |
2018-12-04 |
National University Of Singapore |
Chimeric receptors and uses thereof in immune therapy
|
|
WO2015058018A1
(en)
*
|
2013-10-17 |
2015-04-23 |
National University Of Singapore |
Chimeric receptor that triggers antibody-dependent cell cytotoxicity against multiple tumors
|
|
KR102211120B1
(ko)
|
2014-05-15 |
2021-02-03 |
내셔널 유니버시티 오브 싱가포르 |
변형된 천연 살해 세포 및 그의 용도
|
|
US20170151281A1
(en)
|
2015-02-19 |
2017-06-01 |
Batu Biologics, Inc. |
Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
|
|
BR112017024757A2
(pt)
|
2015-05-18 |
2018-11-13 |
TCR2 Therapeutics Inc. |
composições e métodos para reprogramação de tcr utilizando proteínas de fusão
|
|
WO2017161333A1
(en)
*
|
2016-03-18 |
2017-09-21 |
Unum Therapeutics |
Modified chimeric receptors and uses thereof in immune therapy
|
|
WO2017205254A1
(en)
*
|
2016-05-23 |
2017-11-30 |
Unum Therapeutics |
Immune cells expressing antibody-coupled t-cell receptor (actr) for use in inhibiting cancer cells expressing surface immunoglobulin
|
|
WO2018017649A1
(en)
*
|
2016-07-19 |
2018-01-25 |
Unum Therapeutics Inc. |
Use of antibody-coupled t cell receptor (actr) with multiple anti-cancer antibodies in cancer treatment
|
|
WO2018026953A1
(en)
|
2016-08-02 |
2018-02-08 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
MX2019003899A
(es)
|
2016-10-07 |
2019-08-14 |
Tcr2 Therapeutics Inc |
Composiciones y metodos para reprogramacion de receptores de linfocitos t mediante el uso de proteinas de fusion.
|
|
AU2017363311A1
(en)
|
2016-11-22 |
2019-06-13 |
TCR2 Therapeutics Inc. |
Compositions and methods for TCR reprogramming using fusion proteins
|
|
JP7685735B2
(ja)
|
2016-12-02 |
2025-05-30 |
アンヘレス セラピューティクス インコーポレイテッド |
合成免疫受容体およびその使用方法
|
|
WO2018112266A1
(en)
*
|
2016-12-14 |
2018-06-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Il-13 superkine: immune cell targeting constructs and methods of use thereof
|
|
WO2018132506A1
(en)
|
2017-01-10 |
2018-07-19 |
The General Hospital Corporation |
Chimeric antigen receptors based on alternative signal 1 domains
|
|
AU2018213407A1
(en)
*
|
2017-01-30 |
2019-08-08 |
Unum Therapeutics Inc. |
Improved antibody-coupled T cell receptor constructs and therapeutic uses thereof
|
|
CA3053640A1
(en)
*
|
2017-02-17 |
2018-08-23 |
Unum Therapeutics Inc. |
Co-use of anti-bcma antibody and antibody-coupled t celll receptor (actr) in cancer therapy and b cell disorders
|
|
EP3595721B1
(en)
*
|
2017-03-16 |
2025-07-09 |
The General Hospital Corporation |
Chimeric antigen receptors targeting cd37
|
|
BR112019017629A2
(pt)
*
|
2017-03-27 |
2020-04-07 |
Hoffmann La Roche |
receptor de união ao antígeno, polinucleotídeo isolado, vetor, célula t transduzida, métodos para o tratamento de uma doença e para induzir a lise, utilização do receptor e receptor
|
|
IL269553B2
(en)
|
2017-03-27 |
2025-10-01 |
Nat Univ Singapore |
Truncated NKG2D chimeric receptors and their uses in immunotherapy with natural killer cells
|
|
WO2018182511A1
(en)
|
2017-03-27 |
2018-10-04 |
National University Of Singapore |
Stimulatory cell lines for ex vivo expansion and activation of natural killer cells
|
|
IL269531B2
(en)
|
2017-03-27 |
2024-10-01 |
Hoffmann La Roche |
Improved antigen binding receptors
|
|
US11891644B2
(en)
|
2017-06-07 |
2024-02-06 |
Seagen Inc. |
T cells with reduced surface fucosylation and methods of making and using the same
|
|
CA3072908A1
(en)
*
|
2017-09-06 |
2019-03-14 |
Fred Hutchinson Cancer Research Center |
Strep-tag specific binding proteins and uses thereof
|
|
CA3078434A1
(en)
|
2017-10-10 |
2019-04-18 |
Medicenna Therapeutics, Inc. |
Il-4-fusion formulations for treatment of central nervous system (cns) tumors
|
|
AU2018355462B9
(en)
*
|
2017-10-26 |
2022-04-28 |
Regents Of The University Of Minnesota |
Recombinant immune cells, methods of making, and methods of use
|
|
CA3079096A1
(en)
*
|
2017-11-01 |
2019-05-09 |
Allogene Therapeutics, Inc. |
Modified caspase-9 polypeptides and methods of use thereof
|
|
BR112020008568A2
(pt)
*
|
2017-11-09 |
2020-10-06 |
Sangamo Therapeutics, Inc. |
modificação genética de gene de proteína contendo sh2 indutível por citoquina (cish)
|
|
CN111683962B
(zh)
|
2017-11-10 |
2025-05-16 |
美国政府(由卫生和人类服务部的部长所代表) |
靶向肿瘤抗原的嵌合抗原受体
|
|
CN111373031A
(zh)
|
2017-11-10 |
2020-07-03 |
朱拉生物公司 |
基于主要组织相容性复合物的嵌合受体和其用于治疗自身免疫性疾病的用途
|
|
BR112020012336A2
(pt)
|
2017-12-19 |
2021-03-30 |
Akouos, Inc. |
Administração de anticorpos terapêuticos mediada por aav para o ouvido interno
|
|
CN109970864A
(zh)
*
|
2017-12-28 |
2019-07-05 |
上海细胞治疗研究院 |
一种双向激活共刺激分子受体及其用途
|
|
KR20200115511A
(ko)
*
|
2017-12-29 |
2020-10-07 |
시티 오브 호프 |
메디토프-이용 가능한 t 세포
|
|
CN111801348A
(zh)
|
2018-02-09 |
2020-10-20 |
新加坡国立大学 |
活化性嵌合受体及其在自然杀伤细胞免疫疗法中的用途
|
|
KR102593359B1
(ko)
*
|
2018-03-19 |
2023-10-24 |
사바 라이프 사이언스 에이비 |
Adcc 및 adcp 활성의 향상된 정량화를 위한 시스템 및 제품
|
|
SG11202008976YA
(en)
|
2018-04-02 |
2020-10-29 |
Nat Univ Singapore |
Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells
|
|
IL321548A
(en)
|
2018-05-22 |
2025-08-01 |
Immunitybio Inc |
Recombinant NK cells expressing a chimeric antigen receptor (CAR) for epsilon-FC and uses thereof
|
|
CA3102097A1
(en)
|
2018-06-01 |
2019-12-05 |
The Board Of Trustees Of The Leland Stanford Junior Unversity |
Il-13/il-4 superkines: immune cell targeting constructs and methods of use thereof
|
|
AU2019299439C1
(en)
|
2018-07-03 |
2025-06-26 |
Sotio Biotech, Inc. |
Chimeric receptors in combination with trans metabolism molecules enhancing glucose import and therapeutic uses thereof
|
|
JP7456638B2
(ja)
|
2018-08-14 |
2024-03-27 |
ソティオ，リミティド ライアビリティ カンパニー |
クレブス回路を調節するトランス代謝分子と組み合わせたキメラ抗原受容体ポリペプチド、及び、それらの治療的使用
|
|
EP3844186A4
(en)
|
2018-08-29 |
2022-08-17 |
National University of Singapore |
METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS
|
|
US20240165232A1
(en)
*
|
2018-09-24 |
2024-05-23 |
Fred Hutchinson Cancer Research Center |
Chimeric receptor proteins and uses thereof
|
|
EP3876977A1
(en)
|
2018-11-06 |
2021-09-15 |
The Regents Of The University Of California |
Chimeric antigen receptors for phagocytosis
|
|
CA3120563A1
(en)
|
2018-11-26 |
2020-06-04 |
Nkarta, Inc. |
Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
|
|
WO2020180882A1
(en)
|
2019-03-05 |
2020-09-10 |
Nkarta, Inc. |
Cd19-directed chimeric antigen receptors and uses thereof in immunotherapy
|
|
EP3941492A4
(en)
*
|
2019-03-19 |
2023-05-03 |
Ramot at Tel-Aviv University Ltd. |
T-CELL EXPRESSING A FC GAMMA RECEPTOR AND METHODS OF USE THEREOF
|
|
JPWO2020213724A1
(enExample)
|
2019-04-19 |
2020-10-22 |
|
|
|
US11013764B2
(en)
|
2019-04-30 |
2021-05-25 |
Myeloid Therapeutics, Inc. |
Engineered phagocytic receptor compositions and methods of use thereof
|
|
CN110592014A
(zh)
*
|
2019-08-14 |
2019-12-20 |
广东美赛尔细胞生物科技有限公司 |
一种在nk细胞治疗中免辐照体外体内持续去除饲养细胞的方法
|
|
KR20220097875A
(ko)
|
2019-09-03 |
2022-07-08 |
마이얼로이드 테라퓨틱스, 인크. |
게놈 통합을 위한 방법 및 조성물
|
|
CN111944062B
(zh)
*
|
2019-12-09 |
2023-11-07 |
深圳市体内生物医药科技有限公司 |
一种识别Fc片段的嵌合抗原受体及其应用
|
|
US10980836B1
(en)
|
2019-12-11 |
2021-04-20 |
Myeloid Therapeutics, Inc. |
Therapeutic cell compositions and methods of manufacturing and use thereof
|
|
CN111100942B
(zh)
*
|
2019-12-31 |
2023-03-28 |
海南波莲水稻基因科技有限公司 |
与水稻光温敏核雄性不育表型相关的分子标记和应用
|
|
JP7466231B2
(ja)
*
|
2020-02-13 |
2024-04-12 |
四川大学 |
キメラ抗原受容体及びその適用
|
|
EP3875478A1
(en)
*
|
2020-03-05 |
2021-09-08 |
Canvax Biotech, S.L. |
Novel non-immunogenic chimeric antigen receptors and uses thereof
|
|
IL299276A
(en)
|
2020-06-22 |
2023-02-01 |
Univ Ramot |
Multi subunit protein modules, cells expressing same and uses thereof
|
|
CN113583139A
(zh)
*
|
2020-07-06 |
2021-11-02 |
上海鑫湾生物科技有限公司 |
一种嵌合受体及其应用
|
|
CN116194124A
(zh)
|
2020-07-31 |
2023-05-30 |
中外制药株式会社 |
包含表达嵌合受体的细胞的药物组合物
|
|
EP4198120A4
(en)
*
|
2020-08-14 |
2024-05-08 |
Shanghai Xinghua Bio Pharmaceutical Science & Technology Co., Ltd |
METHOD FOR PREPARING UNIVERSAL IMMUNE CELLS AND THEIR USE
|
|
CN111876382A
(zh)
*
|
2020-08-14 |
2020-11-03 |
上海星华生物医药科技有限公司 |
一种制备通用型免疫细胞的方法及其应用
|
|
JP2023549140A
(ja)
|
2020-11-04 |
2023-11-22 |
マイエロイド・セラピューティクス，インコーポレーテッド |
操作されたキメラ融合タンパク質組成物およびその使用方法
|
|
IL303317A
(en)
|
2020-12-01 |
2023-07-01 |
Akouos Inc |
ANTI-NATURAL ANTIBODY STRUCTURES AND RELATED METHODS FOR THE TREATMENT OF SYMPTOMS ASSOCIATED WITH VESTIBULAR SWANNOMA
|
|
CN116964082A
(zh)
*
|
2020-12-22 |
2023-10-27 |
免疫生物公司 |
Fc受体CAR构建体和细胞
|
|
WO2022150379A1
(en)
*
|
2021-01-08 |
2022-07-14 |
Regents Of The University Of Minnesota |
Nk cell engager molecules and methods of use
|
|
KR20240013094A
(ko)
|
2021-03-17 |
2024-01-30 |
마이얼로이드 테라퓨틱스, 인크. |
조작된 키메라 융합 단백질 조성물 및 그의 사용 방법
|
|
BR112023023642A2
(pt)
|
2021-05-11 |
2024-01-30 |
Myeloid Therapeutics Inc |
Métodos e composições para integração genômica
|
|
JP2024536859A
(ja)
|
2021-09-27 |
2024-10-08 |
ソティオ バイオテック インコーポレイティド |
解糖経路からグルコース代謝産物を再誘導するトランス代謝分子と組み合わせたキメラ受容体ポリペプチド及びその治療的使用
|
|
AU2022388928A1
(en)
|
2021-11-16 |
2024-05-16 |
Sotio Biotech Inc. |
Treatment of myxoid/round cell liposarcoma patients
|
|
CN114685662B
(zh)
*
|
2022-03-30 |
2022-12-27 |
河北森朗生物科技有限公司 |
抗cd7纳米抗体、衍生物及其在肿瘤治疗中的应用
|
|
WO2024040207A1
(en)
|
2022-08-19 |
2024-02-22 |
Sotio Biotech Inc. |
Genetically engineered natural killer (nk) cells with chimeric receptor polypeptides in combination with trans metabolism molecules and therapeutic uses thereof
|
|
WO2024040208A1
(en)
|
2022-08-19 |
2024-02-22 |
Sotio Biotech Inc. |
Genetically engineered immune cells with chimeric receptor polypeptides in combination with multiple trans metabolism molecules and therapeutic uses thereof
|
|
WO2024102954A1
(en)
*
|
2022-11-10 |
2024-05-16 |
Massachusetts Institute Of Technology |
Activation induced clipping system (aics)
|
|
EP4694916A1
(en)
|
2023-04-14 |
2026-02-18 |
SOTIO Biotech Inc. |
Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists
|
|
WO2024215987A1
(en)
|
2023-04-14 |
2024-10-17 |
Sotio Biotech Inc. |
IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES
|
|
KR20260024373A
(ko)
*
|
2023-05-05 |
2026-02-20 |
더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 |
다중-수용체 자연 살해 세포
|
|
WO2025103439A1
(zh)
*
|
2023-11-16 |
2025-05-22 |
广州瑞风生物科技有限公司 |
一种嵌合抗原受体及其应用
|
|
KR102764613B1
(ko)
*
|
2024-03-28 |
2025-02-12 |
한양대학교 에리카산학협력단 |
NaPi2b 특이적 CAR-T를 포함하는 난소암 치료용 약학 조성물
|
|
WO2025235862A1
(en)
*
|
2024-05-10 |
2025-11-13 |
Inndura Therapeutics Inc. |
A modified immune cell receptor comprising a target-binding domain and the extracellular domain of cd16a
|
|
WO2026077463A1
(zh)
*
|
2024-10-12 |
2026-04-16 |
深圳市济因生物科技有限公司 |
一种嵌合蛋白和工程化免疫细胞及其制备方法与应用
|