CN107074969A - 嵌合受体及其在免疫治疗中的应用 - Google Patents

嵌合受体及其在免疫治疗中的应用 Download PDF

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CN107074969A
CN107074969A CN201580048652.5A CN201580048652A CN107074969A CN 107074969 A CN107074969 A CN 107074969A CN 201580048652 A CN201580048652 A CN 201580048652A CN 107074969 A CN107074969 A CN 107074969A
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C·威尔逊
K·麦金尼斯
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Younum Therapeutics Inc
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Younum Therapeutics Inc
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CN201580048652.5A 2014-09-09 2015-09-09 嵌合受体及其在免疫治疗中的应用 Pending CN107074969A (zh)

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US201462047916P 2014-09-09 2014-09-09
US62/047,916 2014-09-09
PCT/US2015/049126 WO2016040441A1 (en) 2014-09-09 2015-09-09 Chimeric receptors and uses thereof in immune therapy

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US (1) US20180133252A9 (enExample)
EP (1) EP3191507A1 (enExample)
JP (1) JP2017527310A (enExample)
KR (1) KR20170073593A (enExample)
CN (1) CN107074969A (enExample)
AU (1) AU2015315199B2 (enExample)
BR (1) BR112017004675A2 (enExample)
CA (1) CA2972714A1 (enExample)
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CN109970864A (zh) * 2017-12-28 2019-07-05 上海细胞治疗研究院 一种双向激活共刺激分子受体及其用途
CN110592014A (zh) * 2019-08-14 2019-12-20 广东美赛尔细胞生物科技有限公司 一种在nk细胞治疗中免辐照体外体内持续去除饲养细胞的方法
CN111065409A (zh) * 2017-09-06 2020-04-24 弗雷德哈钦森癌症研究中心 Strep-tag特异性结合蛋白及其用途
CN111100942A (zh) * 2019-12-31 2020-05-05 海南波莲水稻基因科技有限公司 与水稻光温敏核雄性不育表型相关的分子标记和应用
CN111295189A (zh) * 2017-11-01 2020-06-16 艾洛基治疗公司 修饰的胱天蛋白酶-9多肽及其使用方法
CN111373031A (zh) * 2017-11-10 2020-07-03 朱拉生物公司 基于主要组织相容性复合物的嵌合受体和其用于治疗自身免疫性疾病的用途
CN111876382A (zh) * 2020-08-14 2020-11-03 上海星华生物医药科技有限公司 一种制备通用型免疫细胞的方法及其应用
CN111936171A (zh) * 2017-12-19 2020-11-13 阿库斯股份有限公司 Aav介导的治疗性抗体到内耳的递送
CN111944062A (zh) * 2019-12-09 2020-11-17 深圳市体内生物医药科技有限公司 一种识别Fc片段的嵌合抗原受体及其应用
CN112534046A (zh) * 2018-05-22 2021-03-19 南克维斯特公司 FC-ε CAR
CN113583139A (zh) * 2020-07-06 2021-11-02 上海鑫湾生物科技有限公司 一种嵌合受体及其应用
WO2022032665A1 (zh) * 2020-08-14 2022-02-17 上海星华生物医药科技有限公司 一种制备通用型免疫细胞的方法及其应用
WO2025103439A1 (zh) * 2023-11-16 2025-05-22 广州瑞风生物科技有限公司 一种嵌合抗原受体及其应用
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JP6936934B2 (ja) 2013-09-24 2021-09-22 メディシナ セラピューティクス インコーポレイテッド インターロイキン−４受容体結合融合タンパク質及びその使用
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SG11201602979RA (en) * 2013-10-17 2016-05-30 Univ Singapore Chimeric receptor that triggers antibody-dependent cell cytotoxicity against multiple tumors
KR20210014210A (ko) 2014-05-15 2021-02-08 내셔널 유니버시티 오브 싱가포르 변형된 천연 살해 세포 및 그의 용도
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WO2018102795A2 (en) 2016-12-02 2018-06-07 University Of Southern California Synthetic immune receptors and methods of use thereof
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CN110582298A (zh) * 2017-02-17 2019-12-17 优努姆治疗公司 抗bcma抗体和抗体偶联t细胞受体(actr)在癌症治疗和b细胞疾病中的联合使用
CN118599009A (zh) * 2017-03-16 2024-09-06 综合医院公司 靶向cd37的嵌合抗原受体
MX2019011526A (es) * 2017-03-27 2019-12-05 Hoffmann La Roche Receptores de union a antigeno mejorados.
CA3054104A1 (en) * 2017-03-27 2018-10-04 F. Hoffmann-La Roche Ag Improved antigen binding receptor formats
CA3056439A1 (en) 2017-03-27 2018-10-04 National University Of Singapore Truncated nkg2d chimeric receptors and uses thereof in natural killer cell immunotherapy
AU2018245749A1 (en) 2017-03-27 2019-10-03 National University Of Singapore Stimulatory cell lines for ex vivo expansion and activation of natural killer cells
IL271012B2 (en) 2017-06-07 2023-12-01 Seagen Inc T cells with reduced surface fucosylation and methods for their preparation and use
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