CN107074969A - 嵌合受体及其在免疫治疗中的应用 - Google Patents

嵌合受体及其在免疫治疗中的应用 Download PDF

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CN107074969A
CN107074969A CN201580048652.5A CN201580048652A CN107074969A CN 107074969 A CN107074969 A CN 107074969A CN 201580048652 A CN201580048652 A CN 201580048652A CN 107074969 A CN107074969 A CN 107074969A
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C·威尔逊
K·麦金尼斯
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Younum Therapeutics Inc
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CN201580048652.5A 2014-09-09 2015-09-09 嵌合受体及其在免疫治疗中的应用 Pending CN107074969A (zh)

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US201462047916P 2014-09-09 2014-09-09
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PCT/US2015/049126 WO2016040441A1 (en) 2014-09-09 2015-09-09 Chimeric receptors and uses thereof in immune therapy

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CN109970864A (zh) * 2017-12-28 2019-07-05 上海细胞治疗研究院 一种双向激活共刺激分子受体及其用途
CN110592014A (zh) * 2019-08-14 2019-12-20 广东美赛尔细胞生物科技有限公司 一种在nk细胞治疗中免辐照体外体内持续去除饲养细胞的方法
CN111065409A (zh) * 2017-09-06 2020-04-24 弗雷德哈钦森癌症研究中心 Strep-tag特异性结合蛋白及其用途
CN111100942A (zh) * 2019-12-31 2020-05-05 海南波莲水稻基因科技有限公司 与水稻光温敏核雄性不育表型相关的分子标记和应用
CN111295189A (zh) * 2017-11-01 2020-06-16 艾洛基治疗公司 修饰的胱天蛋白酶-9多肽及其使用方法
CN111373031A (zh) * 2017-11-10 2020-07-03 朱拉生物公司 基于主要组织相容性复合物的嵌合受体和其用于治疗自身免疫性疾病的用途
CN111876382A (zh) * 2020-08-14 2020-11-03 上海星华生物医药科技有限公司 一种制备通用型免疫细胞的方法及其应用
CN111936171A (zh) * 2017-12-19 2020-11-13 阿库斯股份有限公司 Aav介导的治疗性抗体到内耳的递送
CN111944062A (zh) * 2019-12-09 2020-11-17 深圳市体内生物医药科技有限公司 一种识别Fc片段的嵌合抗原受体及其应用
CN112534046A (zh) * 2018-05-22 2021-03-19 南克维斯特公司 FC-ε CAR
CN113583139A (zh) * 2020-07-06 2021-11-02 上海鑫湾生物科技有限公司 一种嵌合受体及其应用
WO2022032665A1 (zh) * 2020-08-14 2022-02-17 上海星华生物医药科技有限公司 一种制备通用型免疫细胞的方法及其应用
WO2025103439A1 (zh) * 2023-11-16 2025-05-22 广州瑞风生物科技有限公司 一种嵌合抗原受体及其应用
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EP3049526B1 (en) 2013-09-24 2021-02-24 Medicenna Therapeutics, Inc. Interleukin-4 receptor-binding fusion proteins and uses thereof
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KR102308597B1 (ko) * 2013-10-17 2021-10-01 내셔널 유니버시티 오브 싱가포르 다중 종양에 대항하여 항체-의존성 세포 세포독성을 촉발시키는 키메라 수용체
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WO2018112266A1 (en) * 2016-12-14 2018-06-21 The Board Of Trustees Of The Leland Stanford Junior University Il-13 superkine: immune cell targeting constructs and methods of use thereof
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EP3573660A4 (en) * 2017-01-30 2021-01-06 Unum Therapeutics Inc. IMPROVED ANTIBODY T-LYMPHOCYTE RECEPTOR CONSTRUCTIONS AND THEIR THERAPEUTIC USES
US20190381171A1 (en) * 2017-02-17 2019-12-19 Unum Therapeutics Inc. Co-use of anti-bcma antibody and antibody-coupled t cell receptor (actr) in cancer therapy and b cell disorders
AU2018236450A1 (en) * 2017-03-16 2019-10-03 The General Hospital Corporation Chimeric antigen receptors targeting CD37
IL269553B2 (en) 2017-03-27 2025-10-01 Nat Univ Singapore Truncated NKG2D chimeric receptors and their uses in immunotherapy with natural killer cells
CA3056837A1 (en) * 2017-03-27 2018-10-04 F. Hoffmann-La Roche Ag Improved antigen binding receptors
JP2020511979A (ja) * 2017-03-27 2020-04-23 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 改良された抗原結合受容体フォーマット
MX2019011570A (es) 2017-03-27 2019-11-18 Nat Univ Singapore Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.
EA201992875A1 (ru) 2017-06-07 2020-03-25 Сиэтл Дженетикс, Инк. T-клетки со сниженным поверхностным фукозилированием и способы их получения и применения
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