JP2017522300A5 - - Google Patents
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- Publication number
- JP2017522300A5 JP2017522300A5 JP2016575499A JP2016575499A JP2017522300A5 JP 2017522300 A5 JP2017522300 A5 JP 2017522300A5 JP 2016575499 A JP2016575499 A JP 2016575499A JP 2016575499 A JP2016575499 A JP 2016575499A JP 2017522300 A5 JP2017522300 A5 JP 2017522300A5
- Authority
- JP
- Japan
- Prior art keywords
- dihydro
- benzoxazin
- oxo
- carbonyl
- acetamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462018790P | 2014-06-30 | 2014-06-30 | |
| US62/018,790 | 2014-06-30 | ||
| PCT/GB2015/051860 WO2016001631A1 (en) | 2014-06-30 | 2015-06-26 | Benzoxazinone amides as mineralocorticoid receptor modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017522300A JP2017522300A (ja) | 2017-08-10 |
| JP2017522300A5 true JP2017522300A5 (enExample) | 2018-07-19 |
| JP6368383B2 JP6368383B2 (ja) | 2018-08-01 |
Family
ID=53539739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016575499A Active JP6368383B2 (ja) | 2014-06-30 | 2015-06-26 | 鉱質コルチコイド受容体修飾因子としてのベンゾオキサジノンアミド |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US10017502B2 (enExample) |
| EP (1) | EP3160948B1 (enExample) |
| JP (1) | JP6368383B2 (enExample) |
| KR (1) | KR102012222B1 (enExample) |
| CN (1) | CN106536491B (enExample) |
| AR (1) | AR101036A1 (enExample) |
| AU (1) | AU2015282450C1 (enExample) |
| CA (1) | CA2953655C (enExample) |
| CY (1) | CY1121596T1 (enExample) |
| DK (1) | DK3160948T3 (enExample) |
| EA (1) | EA029518B1 (enExample) |
| ES (1) | ES2707726T3 (enExample) |
| HR (1) | HRP20190147T1 (enExample) |
| HU (1) | HUE042370T2 (enExample) |
| LT (1) | LT3160948T (enExample) |
| ME (1) | ME03316B (enExample) |
| MX (1) | MX367404B (enExample) |
| PL (1) | PL3160948T3 (enExample) |
| PT (1) | PT3160948T (enExample) |
| RS (1) | RS58274B1 (enExample) |
| SI (1) | SI3160948T1 (enExample) |
| SM (1) | SMT201900039T1 (enExample) |
| TR (1) | TR201900659T4 (enExample) |
| TW (1) | TWI677498B (enExample) |
| UY (1) | UY36195A (enExample) |
| WO (1) | WO2016001631A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS58274B1 (sr) * | 2014-06-30 | 2019-03-29 | Astrazeneca Ab | Benzoksazinon amidi kao modulatori mineralokortikoidnog receptora |
| WO2020016335A1 (en) | 2018-07-19 | 2020-01-23 | Astrazeneca Ab | Methods of treating hfpef employing dapagliflozin and compositions comprising the same |
| CN112107568B (zh) * | 2019-06-19 | 2022-03-25 | 北京龙嘉博创医药科技有限公司 | 二芳基酰胺类化合物及其应用 |
| EP4021507A1 (en) | 2019-08-30 | 2022-07-06 | AstraZeneca AB | Methods of treating heart failure with reduced ejection fraction with dapagliflozin |
| TW202220672A (zh) | 2020-07-27 | 2022-06-01 | 瑞典商阿斯特捷利康公司 | 用達格列淨治療慢性腎臟病之方法 |
| SI4188389T1 (sl) | 2020-07-27 | 2025-11-28 | Astrazeneca Ab | Dapagliflozin za uporabo pri postopkih zdravljenja kronične ledvične bolezni |
| WO2022262736A1 (zh) | 2021-06-15 | 2022-12-22 | 正大天晴药业集团股份有限公司 | 苯并恶嗪酮类衍生物 |
| TW202409023A (zh) | 2022-07-14 | 2024-03-01 | 美商富曼西公司 | 除草苯并𠯤 |
| CA3266292A1 (en) | 2022-09-01 | 2024-03-07 | Astrazeneca Ab | COMBINATION OF SGLT2 INHIBITORS AND MINERALOCORTICOID RECEPTOR MODULATORS INTENDED FOR USE IN THE TREATMENT OF HEART DISEASE |
| CN120344508A (zh) * | 2022-12-15 | 2025-07-18 | 正大天晴药业集团股份有限公司 | 苯并恶嗪酮类化合物的结晶及其制备 |
| WO2025111184A1 (en) | 2023-11-21 | 2025-05-30 | Fmc Corporation | Substituted tetrahydroquinoline and tetrahydroquinoxaline herbicides |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002085868A1 (en) * | 2001-04-23 | 2002-10-31 | Astrazeneca Ab | Benzoxazinone derivatives for use in the treatment of angiogenesis |
| JP2006512357A (ja) * | 2002-12-20 | 2006-04-13 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | Ｐｉ３ｋの阻害剤としてのベンゾキサジンおよびその誘導体 |
| KR20070056060A (ko) * | 2004-07-14 | 2007-05-31 | 리간드 파마슈티칼스 인코포레이티드 | 세포내 수용체 조절화합물 및 방법 |
| KR20070046150A (ko) | 2004-07-28 | 2007-05-02 | 아이알엠 엘엘씨 | 스테로이드 호르몬 핵 수용체의 조절제로서의 화합물 및조성물 |
| CA2635541A1 (en) | 2005-12-28 | 2007-07-12 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compounds and their use as mineralocorticoid receptor ligands |
| TWI385161B (zh) | 2006-02-02 | 2013-02-11 | Mitsubishi Tanabe Pharma Corp | 含氮雜雙環化合物 |
| KR101107800B1 (ko) | 2006-10-31 | 2012-01-25 | 화이자 프로덕츠 인코포레이티드 | 무기질코르티코이드 수용체 길항제로서의 피라졸린 화합물 |
| DE102007009494A1 (de) | 2007-02-27 | 2008-08-28 | Bayer Healthcare Ag | Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung |
| US8063090B2 (en) | 2007-03-23 | 2011-11-22 | Merck Sharp & Dohme Corp. | Mineralocorticoid receptor modulators |
| PL2133330T3 (pl) | 2007-04-09 | 2014-06-30 | Daiichi Sankyo Co Ltd | Atropoizomer pochodnej pirolu |
| JP5173653B2 (ja) * | 2007-08-01 | 2013-04-03 | 田辺三菱製薬株式会社 | 医薬組成物 |
| US8258131B2 (en) | 2007-08-01 | 2012-09-04 | Mitsubishi Tanabe Pharma Corporation | Fused bicyclic compound |
| TWI431010B (zh) | 2007-12-19 | 2014-03-21 | Lilly Co Eli | 礦皮質素受體拮抗劑及使用方法 |
| UY31905A (es) * | 2008-06-18 | 2010-01-29 | Astrazeneca Ab | Derivados de benzoxazinona, procesos de preparación, composiciones farmacéuticas conteniéndolos y aplicaciones. |
| US20100094000A1 (en) | 2008-09-03 | 2010-04-15 | Takeda Pharmaceutical Company Limited | Pyrazole compounds |
| WO2010098286A1 (ja) | 2009-02-25 | 2010-09-02 | 第一三共株式会社 | ミネラルコルチコイド受容体拮抗薬を含有する医薬 |
| US8658638B2 (en) | 2009-03-12 | 2014-02-25 | Eli Lilly And Company | Mineralocorticoid receptor antagonist and methods of use |
| WO2010116282A1 (en) | 2009-04-10 | 2010-10-14 | Pfizer Inc. | 4, 5-dihydro-lh-pyrazole compounds and their pharmaceutical uses |
| WO2011141848A1 (en) | 2010-05-11 | 2011-11-17 | Pfizer Inc. | Morpholine compounds as mineralocorticoid receptor antagonists |
| US8979337B2 (en) | 2010-05-11 | 2015-03-17 | Koninklijke Philips N.V. | Lighting module |
| US20130116227A1 (en) | 2010-07-13 | 2013-05-09 | Dainippon Sumitomo Pharma Co., Ltd. | Biaryl amide derivative or pharmaceutically acceptable salt thereof |
| JP2013542255A (ja) | 2010-11-10 | 2013-11-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ミネラルコルチコイド受容体アンタゴニストとしてのピリジル尿素 |
| RS58274B1 (sr) * | 2014-06-30 | 2019-03-29 | Astrazeneca Ab | Benzoksazinon amidi kao modulatori mineralokortikoidnog receptora |
-
2015
- 2015-06-26 RS RS20190085A patent/RS58274B1/sr unknown
- 2015-06-26 WO PCT/GB2015/051860 patent/WO2016001631A1/en not_active Ceased
- 2015-06-26 ES ES15736015T patent/ES2707726T3/es active Active
- 2015-06-26 SM SM20190039T patent/SMT201900039T1/it unknown
- 2015-06-26 KR KR1020177002518A patent/KR102012222B1/ko active Active
- 2015-06-26 PL PL15736015T patent/PL3160948T3/pl unknown
- 2015-06-26 PT PT15736015T patent/PT3160948T/pt unknown
- 2015-06-26 CN CN201580035032.8A patent/CN106536491B/zh active Active
- 2015-06-26 CA CA2953655A patent/CA2953655C/en active Active
- 2015-06-26 UY UY0001036195A patent/UY36195A/es not_active Application Discontinuation
- 2015-06-26 EP EP15736015.7A patent/EP3160948B1/en active Active
- 2015-06-26 TR TR2019/00659T patent/TR201900659T4/tr unknown
- 2015-06-26 AU AU2015282450A patent/AU2015282450C1/en active Active
- 2015-06-26 US US15/320,379 patent/US10017502B2/en active Active
- 2015-06-26 MX MX2017000183A patent/MX367404B/es active IP Right Grant
- 2015-06-26 HU HUE15736015A patent/HUE042370T2/hu unknown
- 2015-06-26 HR HRP20190147TT patent/HRP20190147T1/hr unknown
- 2015-06-26 LT LTEP15736015.7T patent/LT3160948T/lt unknown
- 2015-06-26 DK DK15736015.7T patent/DK3160948T3/en active
- 2015-06-26 EA EA201790046A patent/EA029518B1/ru not_active IP Right Cessation
- 2015-06-26 JP JP2016575499A patent/JP6368383B2/ja active Active
- 2015-06-26 ME MEP-2019-19A patent/ME03316B/me unknown
- 2015-06-26 SI SI201530572T patent/SI3160948T1/sl unknown
- 2015-06-29 TW TW104120998A patent/TWI677498B/zh active
- 2015-06-29 US US14/753,239 patent/US9394291B2/en active Active
- 2015-06-30 AR ARP150102098A patent/AR101036A1/es active IP Right Grant
-
2019
- 2019-01-24 CY CY20191100097T patent/CY1121596T1/el unknown