JP2017522300A5 - - Google Patents

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Publication number
JP2017522300A5
JP2017522300A5 JP2016575499A JP2016575499A JP2017522300A5 JP 2017522300 A5 JP2017522300 A5 JP 2017522300A5 JP 2016575499 A JP2016575499 A JP 2016575499A JP 2016575499 A JP2016575499 A JP 2016575499A JP 2017522300 A5 JP2017522300 A5 JP 2017522300A5
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JP
Japan
Prior art keywords
dihydro
benzoxazin
oxo
carbonyl
acetamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016575499A
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English (en)
Japanese (ja)
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JP6368383B2 (ja
JP2017522300A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2015/051860 external-priority patent/WO2016001631A1/en
Publication of JP2017522300A publication Critical patent/JP2017522300A/ja
Publication of JP2017522300A5 publication Critical patent/JP2017522300A5/ja
Application granted granted Critical
Publication of JP6368383B2 publication Critical patent/JP6368383B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2016575499A 2014-06-30 2015-06-26 鉱質コルチコイド受容体修飾因子としてのベンゾオキサジノンアミド Active JP6368383B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462018790P 2014-06-30 2014-06-30
US62/018,790 2014-06-30
PCT/GB2015/051860 WO2016001631A1 (en) 2014-06-30 2015-06-26 Benzoxazinone amides as mineralocorticoid receptor modulators

Publications (3)

Publication Number Publication Date
JP2017522300A JP2017522300A (ja) 2017-08-10
JP2017522300A5 true JP2017522300A5 (enExample) 2018-07-19
JP6368383B2 JP6368383B2 (ja) 2018-08-01

Family

ID=53539739

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016575499A Active JP6368383B2 (ja) 2014-06-30 2015-06-26 鉱質コルチコイド受容体修飾因子としてのベンゾオキサジノンアミド

Country Status (26)

Country Link
US (2) US10017502B2 (enExample)
EP (1) EP3160948B1 (enExample)
JP (1) JP6368383B2 (enExample)
KR (1) KR102012222B1 (enExample)
CN (1) CN106536491B (enExample)
AR (1) AR101036A1 (enExample)
AU (1) AU2015282450C1 (enExample)
CA (1) CA2953655C (enExample)
CY (1) CY1121596T1 (enExample)
DK (1) DK3160948T3 (enExample)
EA (1) EA029518B1 (enExample)
ES (1) ES2707726T3 (enExample)
HR (1) HRP20190147T1 (enExample)
HU (1) HUE042370T2 (enExample)
LT (1) LT3160948T (enExample)
ME (1) ME03316B (enExample)
MX (1) MX367404B (enExample)
PL (1) PL3160948T3 (enExample)
PT (1) PT3160948T (enExample)
RS (1) RS58274B1 (enExample)
SI (1) SI3160948T1 (enExample)
SM (1) SMT201900039T1 (enExample)
TR (1) TR201900659T4 (enExample)
TW (1) TWI677498B (enExample)
UY (1) UY36195A (enExample)
WO (1) WO2016001631A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2953655C (en) * 2014-06-30 2020-05-12 Astrazeneca Ab Benzoxazinone amides as mineralocorticoid receptor modulators
SG11202100417RA (en) 2018-07-19 2021-02-25 Astrazeneca Ab Methods of treating hfpef employing dapagliflozin and compositions comprising the same
CN112107568B (zh) * 2019-06-19 2022-03-25 北京龙嘉博创医药科技有限公司 二芳基酰胺类化合物及其应用
MX2020005388A (es) 2019-08-30 2022-10-25 Astrazeneca Ab Uso de composiciones farmacéuticas que comprenden dapagliflozina e inhibidores de sglt2.
TW202220672A (zh) 2020-07-27 2022-06-01 瑞典商阿斯特捷利康公司 用達格列淨治療慢性腎臟病之方法
TWI808786B (zh) * 2021-06-15 2023-07-11 大陸商正大天晴藥業集團股份有限公司 酮類衍生物
TW202409023A (zh) 2022-07-14 2024-03-01 美商富曼西公司 除草苯并𠯤
CR20250276A (es) 2022-09-01 2025-09-04 Astrazeneca Ab Combinación de inhibidores de sglt2 y moduladores del receptor mineralcorticoide para usar en el tratamiento de enfermedades cardiorrenales (divisional 2025-0112)
WO2024125591A1 (zh) * 2022-12-15 2024-06-20 正大天晴药业集团股份有限公司 苯并恶嗪酮类化合物的结晶及其制备
WO2025111184A1 (en) 2023-11-21 2025-05-30 Fmc Corporation Substituted tetrahydroquinoline and tetrahydroquinoxaline herbicides

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002085868A1 (en) * 2001-04-23 2002-10-31 Astrazeneca Ab Benzoxazinone derivatives for use in the treatment of angiogenesis
WO2004056820A1 (en) * 2002-12-20 2004-07-08 Warner-Lambert Company Llc Benzoxazines and derivatives thereof as inhibitors of pi3ks
JP2008506689A (ja) * 2004-07-14 2008-03-06 リガンド・ファーマシューティカルズ・インコーポレイテッド 細胞間受容体のモジュレーター化合物および方法
RU2007107177A (ru) * 2004-07-28 2008-09-10 Айрм Ллк (Bm) Соединения и композиции, как модуляторы ядерных рецепторов стероидных гормонов
AR056893A1 (es) 2005-12-28 2007-10-31 Takeda Pharmaceutical Compuestos heterociclicos fusionados y no fusionados, antagonistas de receptores mineralocorticoides
TWI385161B (zh) 2006-02-02 2013-02-11 Mitsubishi Tanabe Pharma Corp 含氮雜雙環化合物
WO2008053300A1 (en) 2006-10-31 2008-05-08 Pfizer Products Inc. Pyrazoline compounds as mineralocorticoid receptor antagonists
DE102007009494A1 (de) 2007-02-27 2008-08-28 Bayer Healthcare Ag Substituierte 4-Aryl-1, 4-dihydro-1,6-naphthyridinamide und ihre Verwendung
JP2010522168A (ja) 2007-03-23 2010-07-01 メルク・シャープ・エンド・ドーム・コーポレイション 鉱質コルチコイドレセプターモジュレータ
BRPI0809656B8 (pt) 2007-04-09 2021-05-25 Daiichi Sankyo Co Ltd atropisômero, composto, agente profilático ou terapêutico, e, composição farmacêutica
JP5173653B2 (ja) * 2007-08-01 2013-04-03 田辺三菱製薬株式会社 医薬組成物
US8258131B2 (en) 2007-08-01 2012-09-04 Mitsubishi Tanabe Pharma Corporation Fused bicyclic compound
PE20091057A1 (es) 2007-12-19 2009-07-20 Lilly Co Eli Antagonistas del receptor mineralcorticoide y metodos de uso
WO2009154557A1 (en) * 2008-06-18 2009-12-23 Astrazeneca Ab Benzoxazinone derivatives acting as beta2-adrenoreceptor agonist for the treatment of respiratory disorders
US20100094000A1 (en) 2008-09-03 2010-04-15 Takeda Pharmaceutical Company Limited Pyrazole compounds
WO2010098286A1 (ja) 2009-02-25 2010-09-02 第一三共株式会社 ミネラルコルチコイド受容体拮抗薬を含有する医薬
KR101312179B1 (ko) 2009-03-12 2013-09-26 일라이 릴리 앤드 캄파니 미네랄로코르티코이드 수용체 길항제 및 사용 방법
WO2010116282A1 (en) 2009-04-10 2010-10-14 Pfizer Inc. 4, 5-dihydro-lh-pyrazole compounds and their pharmaceutical uses
EP2569576B1 (en) 2010-05-11 2016-07-06 Koninklijke Philips N.V. Lighting module
CA2798831A1 (en) 2010-05-11 2011-11-17 Pfizer Inc. Morpholine compounds as mineralocorticoid receptor antagonists
JPWO2012008435A1 (ja) 2010-07-13 2013-09-09 大日本住友製薬株式会社 ビアリールアミド誘導体またはその薬理学的に許容される塩
EP2638012A1 (en) 2010-11-10 2013-09-18 Boehringer Ingelheim International GmbH Pyridyl ureas as mineralocorticoid receptor antagonists
CA2953655C (en) * 2014-06-30 2020-05-12 Astrazeneca Ab Benzoxazinone amides as mineralocorticoid receptor modulators

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