|
SI2861566T1
(sl)
|
2012-06-13 |
2017-03-31 |
F. Hoffmann-La Roche Ag |
Novi diazaspirocikloalkan in azaspirocikloalkan
|
|
PL2900669T3
(pl)
|
2012-09-25 |
2020-01-31 |
F. Hoffmann-La Roche Ag |
Pochodne heksahydropirolo[3,4-C]pirolu i związki pokrewne jako inhibitory autotaksyny (ATX) oraz inhibitory produkcji kwasu lizofosfatydowego (LPA) do leczenia np. chorób nerek
|
|
AR095079A1
(es)
|
2013-03-12 |
2015-09-16 |
Hoffmann La Roche |
Derivados de octahidro-pirrolo[3,4-c]-pirrol y piridina-fenilo
|
|
AU2014356583B2
(en)
|
2013-11-26 |
2019-02-28 |
F. Hoffmann-La Roche Ag |
New octahydro-cyclobuta (1,2-c;3,4-c')dipyrrol-2-yl
|
|
MA50635A
(fr)
|
2014-03-26 |
2020-08-12 |
Hoffmann La Roche |
Nouveaux composés bicycliques comme inhibiteurs de la production d'autotaxin (atx) et de l'acide lysophosphatidique
|
|
CR20160418A
(es)
|
2014-03-26 |
2016-11-07 |
Hoffmann La Roche |
Nuevos compuestos biciclicos de 7 eslabones
|
|
TWI676626B
(zh)
*
|
2014-04-23 |
2019-11-11 |
美商美國禮來大藥廠 |
抑制瞬時受體電位ａ１離子通道
|
|
TW202140422A
(zh)
|
2014-10-06 |
2021-11-01 |
美商維泰克斯製藥公司 |
囊腫纖維化症跨膜傳導調節蛋白之調節劑
|
|
US10766860B2
(en)
|
2015-03-06 |
2020-09-08 |
Pharmakea, Inc. |
Lysyl oxidase-like 2 inhibitors and uses thereof
|
|
MX376835B
(es)
*
|
2015-03-06 |
2025-03-07 |
Pharmakea Inc |
Inhibidores de lisil oxidasa tipo 2 fluorinados y usos de los mismos.
|
|
MA41898A
(fr)
|
2015-04-10 |
2018-02-13 |
Hoffmann La Roche |
Dérivés de quinazolinone bicyclique
|
|
JP2018519292A
(ja)
*
|
2015-07-01 |
2018-07-19 |
ファーマケア，インク． |
リシルオキシダーゼ様２阻害剤およびその使用
|
|
EP3344619B1
(en)
|
2015-09-04 |
2020-10-28 |
H. Hoffnabb-La Roche Ag |
Phenoxymethyl derivatives
|
|
WO2017050747A1
(en)
|
2015-09-24 |
2017-03-30 |
F. Hoffmann-La Roche Ag |
New bicyclic compounds as dual atx/ca inhibitors
|
|
AU2016328437A1
(en)
|
2015-09-24 |
2018-01-25 |
F. Hoffmann-La Roche Ag |
Bicyclic compounds as ATX inhibitors
|
|
BR112018006080A2
(pt)
|
2015-09-24 |
2018-10-09 |
F. Hoffmann-La Roche Ag |
novos compostos bicíclicos como inibidores de dupla ação de atx/ca
|
|
MA42918A
(fr)
|
2015-09-24 |
2018-08-01 |
Hoffmann La Roche |
Composés bicycliques utilisés en tant qu'inhibiteurs d'atx
|
|
CA3012812A1
(en)
|
2016-02-05 |
2017-08-10 |
Ea Pharma Co., Ltd. |
Heterocyclic sulfonamide derivative and medicine containing same
|
|
CN109476640B
(zh)
*
|
2016-07-20 |
2022-02-25 |
豪夫迈·罗氏有限公司 |
双环脯氨酸化合物
|
|
EP3487849A1
(en)
|
2016-07-20 |
2019-05-29 |
H. Hoffnabb-La Roche Ag |
Sulfonylcycloalkyl carboxamide compounds as trpa1 modulators
|
|
CN109803964A
(zh)
*
|
2016-08-12 |
2019-05-24 |
豪夫迈·罗氏有限公司 |
磺酰基吡啶基trp抑制剂
|
|
SG11201901999XA
(en)
|
2016-09-07 |
2019-04-29 |
Pharmakea Inc |
Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making
|
|
KR20230162996A
(ko)
|
2016-09-07 |
2023-11-29 |
파마케아, 인크. |
리실 옥시다제 유사 2 억제제의 용도
|
|
EA202192783A1
(ru)
|
2016-12-09 |
2022-02-24 |
Вертекс Фармасьютикалз Инкорпорейтед |
Модулятор регулятора трансмембранной проводимости при муковисцидозе, фармацевтические композиции, способы лечения и способ получения указанного модулятора
|
|
WO2018109155A1
(en)
|
2016-12-16 |
2018-06-21 |
Galderma Research & Development |
Trpa1 antagonists for use in the treatment of atopic dermatitis
|
|
KR102515694B1
(ko)
|
2017-01-10 |
2023-03-29 |
바이엘 악티엔게젤샤프트 |
해충 방제제로서의 헤테로사이클 유도체
|
|
EP3596060B1
(en)
|
2017-03-16 |
2023-09-20 |
F. Hoffmann-La Roche AG |
New bicyclic compounds as atx inhibitors
|
|
RU2019132254A
(ru)
|
2017-03-16 |
2021-04-16 |
Ф. Хоффманн-Ля Рош Аг |
Гетероциклические соединения, пригодные в качестве дуальных ингибиторов atx/ca
|
|
MA54105A
(fr)
|
2017-06-08 |
2021-09-15 |
Vertex Pharma |
Méthodes de traitement de la fibrose kystique
|
|
IL272032B2
(en)
|
2017-07-17 |
2026-04-01 |
Vertex Pharma |
Combination therapy for the treatment of cystic fibrosis including N-(1,3-DIMETHYLPYRAZOL-4-YL)SULFONYL-6-[3-(3,3,3-TRIFLUORO-2,2- DIMETHYL-PROPOXY)PYRAZOL-1-YL]-2-[(4S)-2,2,4- TRIMETHYLPYRROLIDIN-1-YL]PYRIDINE-3-CARBOXAMIDE and
|
|
MA49752A
(fr)
|
2017-08-02 |
2021-04-21 |
Vertex Pharma |
Procédés de préparation de composés de pyrrolidine
|
|
KR102678977B1
(ko)
|
2017-09-25 |
2024-06-28 |
씨젠테크 (쑤저우, 차이나) 컴퍼니 리미티드 |
Cxcr4 저해제로서 헤테로아릴 화합물, 그 조성물 및 이용 방법
|
|
CA3078893A1
(en)
|
2017-10-19 |
2019-04-25 |
Vertex Pharmaceuticals Incorporated |
Crystalline forms and compositions of cftr modulators
|
|
KR102716244B1
(ko)
|
2017-12-08 |
2024-10-14 |
버텍스 파마슈티칼스 인코포레이티드 |
낭포성 섬유증 막횡단 전도 조절자의 조정제의 제조 방법
|
|
TWI810243B
(zh)
|
2018-02-05 |
2023-08-01 |
美商維泰克斯製藥公司 |
用於治療囊腫纖化症之醫藥組合物
|
|
TW202000201A
(zh)
|
2018-02-20 |
2020-01-01 |
瑞士商赫孚孟拉羅股份公司 |
製備1-芳基磺醯基-吡咯啶-2-甲醯胺瞬時受體電位通道拮抗劑化合物及其結晶型式之方法
|
|
US10710994B2
(en)
|
2018-03-19 |
2020-07-14 |
Genentech, Inc. |
Oxadiazole transient receptor potential channel inhibitors
|
|
WO2019200246A1
(en)
|
2018-04-13 |
2019-10-17 |
Alexander Russell Abela |
Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator
|
|
WO2020116296A1
(ja)
|
2018-12-07 |
2020-06-11 |
ユニマテック株式会社 |
含フッ素ピリミジン化合物およびその製造方法
|
|
CN110156834A
(zh)
*
|
2019-06-05 |
2019-08-23 |
镇江市高等专科学校 |
一种黄色荧光铜(i)配合物及其制备方法和应用
|
|
JP7471407B2
(ja)
|
2020-05-19 |
2024-04-19 |
ユニマテック株式会社 |
含フッ素ピリミジン化合物および含フッ素ピリミジノン化合物
|
|
FR3114235A1
(fr)
|
2020-09-18 |
2022-03-25 |
Université Grenoble Alpes |
Inhibition du canal trpa1 astrocytaire comme nouvelle cible therapeutique neuroprotectrice dans les phases prodromales de la maladie d’alzheimer
|
|
MX2023005822A
(es)
*
|
2020-11-19 |
2023-05-31 |
Acousia Therapeutics Gmbh |
Composicion de gel no acuoso.
|
|
IT202100015098A1
(it)
|
2021-06-09 |
2022-12-09 |
Flonext S R L |
Composto antagonista del canale trpa1 per uso in patologie degenerative della retina
|
|
WO2023133502A1
(en)
*
|
2022-01-07 |
2023-07-13 |
The Johns Hopkins University |
Treatment and prevention of trigeminal neuralgia
|
|
AR131541A1
(es)
|
2023-01-07 |
2025-04-09 |
Syngenta Crop Protection Ag |
Compuestos de carboxamida novedosos
|
|
WO2025109114A1
(en)
|
2023-11-24 |
2025-05-30 |
Syngenta Crop Protection Ag |
Novel carboxamide compounds
|
|
CN122374291A
(zh)
|
2023-12-12 |
2026-07-10 |
爱杜西亚药品有限公司 |
作为食欲素受体调节剂的芳基砜及砜酮衍生物
|
|
WO2025132542A1
(en)
|
2023-12-19 |
2025-06-26 |
Idorsia Pharmaceuticals Ltd |
Macrocyclic orexin agonists
|
|
WO2025149637A1
(en)
|
2024-01-12 |
2025-07-17 |
Syngenta Crop Protection Ag |
Novel carboxamide compounds
|
|
PY2501648A
(es)
|
2024-01-12 |
2025-10-31 |
Syngenta Crop Protection Ag |
Nuevos compuestos de carboxamida
|
|
WO2025155669A1
(en)
*
|
2024-01-17 |
2025-07-24 |
The Jackson Laboratory |
Trpc3 inhibitors and uses thereof
|
|
WO2026008750A1
(en)
|
2024-07-05 |
2026-01-08 |
Syngenta Crop Protection Ag |
Novel carboxamide compounds
|