JP2017518965A - エンジニアリングされたFc構築物に関連する組成物および方法 - Google Patents

エンジニアリングされたFc構築物に関連する組成物および方法 Download PDF

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JP2017518965A
JP2017518965A JP2016564612A JP2016564612A JP2017518965A JP 2017518965 A JP2017518965 A JP 2017518965A JP 2016564612 A JP2016564612 A JP 2016564612A JP 2016564612 A JP2016564612 A JP 2016564612A JP 2017518965 A JP2017518965 A JP 2017518965A
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domain
domain monomer
polypeptide
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construct
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JP2017518965A5 (enExample
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カルロス ジェイ. ボスケス
カルロス ジェイ. ボスケス
ジェイムズ ヒューストン
ジェイムズ エス. ヒューストン
ジョナサン シー. ランシング
レオナ イー. リング
ジェイムズ ミーダー
ダニエル オルティーズ
ローラ ルティツキー
ビルギット シー. シュルテス
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モメンタ ファーマシューティカルズ インコーポレイテッ
モメンタ ファーマシューティカルズ インコーポレイテッド
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    • A—HUMAN NECESSITIES
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    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
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    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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JP2016564612A 2014-05-02 2015-05-01 エンジニアリングされたFc構築物に関連する組成物および方法 Pending JP2017518965A (ja)

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PCT/US2015/028926 WO2015168643A2 (en) 2014-05-02 2015-05-01 Compositions and methods related to engineered fc constructs

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AU (2) AU2015252866B2 (enExample)
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JP2020514301A (ja) * 2017-01-06 2020-05-21 モメンタ ファーマシューティカルズ インコーポレイテッド 改変されたFc抗原結合ドメイン構築体に関する組成物および方法
JP2023507033A (ja) * 2019-12-20 2023-02-20 キソジ・バイオテクノロジー・インコーポレイテッド ポリペプチド、タンパク質複合体及びそれを作製する方法
JP2024532882A (ja) * 2021-08-24 2024-09-10 サンシャイン・レイク・ファーマ・カンパニー・リミテッド Gdf15融合タンパク質及びその使用

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