CN113501880A - 涉及工程化Fc构建体的组合物和方法 - Google Patents

涉及工程化Fc构建体的组合物和方法 Download PDF

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Publication number
CN113501880A
CN113501880A CN202110761899.9A CN202110761899A CN113501880A CN 113501880 A CN113501880 A CN 113501880A CN 202110761899 A CN202110761899 A CN 202110761899A CN 113501880 A CN113501880 A CN 113501880A
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domain
construct
domain monomer
ser
val
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Chinese (zh)
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C·J·博斯克斯
J·S·休斯顿
J·C·兰星
L·E·凌
J·米多尔
D·奥尔蒂斯
L·鲁蒂茨基
B·C·舒尔特斯
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Momenta Pharmaceuticals Inc
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Momenta Pharmaceuticals Inc
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    • A61P37/02—Immunomodulators
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
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    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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CN202110761899.9A 2014-05-02 2015-05-01 涉及工程化Fc构建体的组合物和方法 Pending CN113501880A (zh)

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US201461987863P 2014-05-02 2014-05-02
US61/987863 2014-05-02
US201462081923P 2014-11-19 2014-11-19
US62/081923 2014-11-19
CN201580020385.0A CN106661125B (zh) 2014-05-02 2015-05-01 涉及工程化Fc构建体的组合物和方法

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US (4) US10239944B2 (enExample)
EP (2) EP4299595A3 (enExample)
JP (3) JP2017518965A (enExample)
KR (1) KR102546875B1 (enExample)
CN (2) CN113501880A (enExample)
AU (2) AU2015252866B2 (enExample)
CA (1) CA2941072A1 (enExample)
DK (1) DK3137506T5 (enExample)
ES (1) ES2962694T3 (enExample)
IL (3) IL286367B2 (enExample)
PL (1) PL3137506T3 (enExample)
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