|
EP4282419A1
(en)
|
2012-12-20 |
2023-11-29 |
Purdue Research Foundation |
Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
|
|
WO2014117121A1
(en)
|
2013-01-28 |
2014-07-31 |
St. Jude Children's Research Hospital, Inc. |
A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease
|
|
US9573988B2
(en)
|
2013-02-20 |
2017-02-21 |
Novartis Ag |
Effective targeting of primary human leukemia using anti-CD123 chimeric antigen receptor engineered T cells
|
|
US9657105B2
(en)
|
2013-03-15 |
2017-05-23 |
City Of Hope |
CD123-specific chimeric antigen receptor redirected T cells and methods of their use
|
|
AU2014368892B2
(en)
|
2013-12-20 |
2019-06-13 |
Fred Hutchinson Cancer Center |
Tagged chimeric effector molecules and receptors thereof
|
|
US20160333108A1
(en)
|
2014-01-13 |
2016-11-17 |
Stephen J. Forman |
CHIMERIC ANTIGEN RECEPTORS (CARs) HAVING MUTATIONS IN THE FC SPACER REGION AND METHODS FOR THEIR USE
|
|
AU2015243849B2
(en)
|
2014-04-10 |
2020-12-17 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Transgene genetic tags and methods of use
|
|
KR102211120B1
(ko)
|
2014-05-15 |
2021-02-03 |
내셔널 유니버시티 오브 싱가포르 |
변형된 천연 살해 세포 및 그의 용도
|
|
SG11201700770PA
(en)
|
2014-08-19 |
2017-03-30 |
Novartis Ag |
Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment
|
|
EP3587446A1
(en)
*
|
2014-09-19 |
2020-01-01 |
City of Hope |
Costimulatory chimeric antigen receptor t cells targeting il13 r alpha 2
|
|
CA2969704C
(en)
|
2014-12-05 |
2023-05-02 |
City Of Hope |
Cs1 targeted chimeric antigen receptor-modified t cells
|
|
CA3008162A1
(en)
|
2014-12-15 |
2016-06-23 |
The Regents Of The University Of California |
Bispecific or-gate chimeric antigen receptor responsive to cd19 and cd20
|
|
US11384350B2
(en)
|
2014-12-15 |
2022-07-12 |
The Regents Of The University Of California |
Cytotoxic molecules responsive to intracellular ligands for selective T cell mediated killing
|
|
GB201504840D0
(en)
|
2015-03-23 |
2015-05-06 |
Ucl Business Plc |
Chimeric antigen receptor
|
|
HK1252248A1
(zh)
*
|
2015-04-27 |
2019-05-24 |
Abvitro Llc |
对治疗剂和疾病特异性抗原进行测序、确定、配对和验证的方法
|
|
WO2016176652A2
(en)
|
2015-04-29 |
2016-11-03 |
Fred Hutchinson Cancer Research Center |
Modified stem cells and uses thereof
|
|
AU2016265845B2
(en)
|
2015-05-15 |
2020-10-08 |
City Of Hope |
Chimeric antigen receptor compositions
|
|
JP7162530B2
(ja)
*
|
2015-08-07 |
2022-10-28 |
シアトル チルドレンズ ホスピタル （ディービーエイ シアトル チルドレンズ リサーチ インスティテュート） |
固形腫瘍を標的とする二重特異性ｃａｒ ｔ細胞
|
|
ES2911015T3
(es)
|
2015-08-31 |
2022-05-17 |
Helixmith Co Ltd |
Receptores quiméricos de antígeno anti-sialil Tn
|
|
US11466097B2
(en)
*
|
2015-10-06 |
2022-10-11 |
City Of Hope |
Chimeric antigen receptors targeted to PSCA
|
|
CA3001833A1
(en)
*
|
2015-10-13 |
2017-04-20 |
City Of Hope |
Chimeric antigen receptors containing a chlorotoxin domain
|
|
EP3368075B1
(en)
*
|
2015-10-27 |
2020-01-29 |
Board of Regents, The University of Texas System |
Chimeric antigen receptor molecules and uses thereof
|
|
DK3368571T5
(da)
|
2015-10-30 |
2024-09-30 |
Univ California |
Transformerende, vækstfaktor-beta-responsive polypeptider og fremgangsmåder til anvendelse deraf
|
|
CN108779174B
(zh)
*
|
2015-11-04 |
2022-11-29 |
希望之城公司 |
靶向her2的嵌合抗原受体
|
|
BR112018015836A2
(en)
|
2016-02-05 |
2018-12-26 |
City Of Hope |
engineered t-cell administration for central nervous system cancer treatment
|
|
WO2017172952A1
(en)
*
|
2016-04-01 |
2017-10-05 |
Promab Biotechnologies, Inc. |
Flag tagged cd19-car-t cells
|
|
US12144850B2
(en)
|
2016-04-08 |
2024-11-19 |
Purdue Research Foundation |
Methods and compositions for car T cell therapy
|
|
EP3468994A1
(en)
*
|
2016-06-08 |
2019-04-17 |
Intrexon Corporation |
Cd33 specific chimeric antigen receptors
|
|
CN106117366A
(zh)
*
|
2016-06-24 |
2016-11-16 |
安徽未名细胞治疗有限公司 |
一种cd19特异性嵌合抗原受体及其编码基因、应用
|
|
WO2018013563A1
(en)
|
2016-07-12 |
2018-01-18 |
Kite Pharma, Inc. |
Antigen binding molecules and methods of use thereof
|
|
JP2019530440A
(ja)
|
2016-09-02 |
2019-10-24 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
インターロイキン６受容体α結合単鎖可変断片を含む方法および組成物
|
|
WO2018064626A1
(en)
*
|
2016-09-30 |
2018-04-05 |
Baylor College Of Medicine |
Adaptive chimeric antigen receptor t-cell design
|
|
US11116834B2
(en)
|
2016-10-19 |
2021-09-14 |
City Of Hope |
Use of endogenous viral vaccine in chimeric antigen receptor T cell therapy
|
|
US11408005B2
(en)
|
2016-12-12 |
2022-08-09 |
Seattle Children's Hospital |
Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells
|
|
CN108395482B
(zh)
|
2017-02-08 |
2021-02-05 |
西比曼生物科技（香港）有限公司 |
一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定
|
|
WO2018182511A1
(en)
|
2017-03-27 |
2018-10-04 |
National University Of Singapore |
Stimulatory cell lines for ex vivo expansion and activation of natural killer cells
|
|
IL269553B2
(en)
|
2017-03-27 |
2025-10-01 |
Nat Univ Singapore |
Truncated NKG2D chimeric receptors and their uses in immunotherapy with natural killer cells
|
|
KR20240139092A
(ko)
*
|
2017-05-01 |
2024-09-20 |
주노 쎄러퓨티크스 인코퍼레이티드 |
세포 요법 및 면역조절 화합물의 조합
|
|
CA3071661A1
(en)
*
|
2017-09-06 |
2019-03-14 |
Fred Hutchinson Cancer Research Center |
Strep-tag specific chimeric receptors and uses thereof
|
|
US10844371B2
(en)
*
|
2017-09-22 |
2020-11-24 |
Kite Pharma, Inc. |
Antigen binding molecules and methods of use thereof
|
|
WO2019089982A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Method of assessing activity of recombinant antigen receptors
|
|
MX2020004572A
(es)
|
2017-11-01 |
2020-10-07 |
Juno Therapeutics Inc |
Receptores de antigenos quimericos especificos para el antigeno de maduracion de celulas b y polinucleotidos que codifican los mismos.
|
|
WO2019094498A1
(en)
*
|
2017-11-07 |
2019-05-16 |
City Of Hope |
Treatment of cns lymphoma and systemic lymphoma with intracerebroventricularly administered cd19 car
|
|
CN109971712B
(zh)
*
|
2017-12-28 |
2023-06-20 |
上海细胞治疗研究院 |
特异性靶向cd19抗原且高水平稳定表达pd-1抗体的car-t细胞及用途
|
|
CN109971721B
(zh)
*
|
2017-12-28 |
2023-10-31 |
上海细胞治疗研究院 |
自表达cd47抗体的间皮素特异性car-t细胞及其用途
|
|
CN109971714B
(zh)
*
|
2017-12-28 |
2023-06-20 |
上海细胞治疗研究院 |
自表达pd-1抗体并靶向间皮素的嵌合抗原受体修饰t细胞及其用途
|
|
CN109971716B
(zh)
*
|
2017-12-28 |
2023-08-01 |
上海细胞治疗研究院 |
自分泌cd47抗体的egfr特异性car-t细胞及其用途
|
|
CN109971725B
(zh)
|
2017-12-28 |
2024-02-02 |
上海细胞治疗研究院 |
抗体修饰的嵌合抗原受体修饰t细胞及其用途
|
|
CN109971722B
(zh)
*
|
2017-12-28 |
2023-09-01 |
上海细胞治疗研究院 |
靶向cd19且高水平稳定表达cd40抗体的car-t细胞及其用途
|
|
CN109971717B
(zh)
*
|
2017-12-28 |
2023-06-20 |
上海细胞治疗研究院 |
共表达cd40抗体与间皮素特异性嵌合抗原受体的t细胞及其用途
|
|
CN109971723B
(zh)
*
|
2017-12-28 |
2023-07-07 |
上海细胞治疗研究院 |
包含CD40抗体与muc1特异性嵌合抗原受体基因的T细胞及其用途
|
|
US11311576B2
(en)
*
|
2018-01-22 |
2022-04-26 |
Seattle Children's Hospital |
Methods of use for CAR T cells
|
|
CN111801348A
(zh)
|
2018-02-09 |
2020-10-20 |
新加坡国立大学 |
活化性嵌合受体及其在自然杀伤细胞免疫疗法中的用途
|
|
CA3091674A1
(en)
|
2018-02-23 |
2019-08-29 |
Endocyte, Inc. |
Sequencing method for car t cell therapy
|
|
EP3759130A1
(en)
*
|
2018-02-26 |
2021-01-06 |
Fred Hutchinson Cancer Research Center |
Compositions and methods for cellular immunotherapy
|
|
SG11202008976YA
(en)
|
2018-04-02 |
2020-10-29 |
Nat Univ Singapore |
Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells
|
|
CN112566643A
(zh)
*
|
2018-06-12 |
2021-03-26 |
加利福尼亚大学董事会 |
用于治疗癌症的单链双特异性嵌合抗原受体
|
|
JP7459046B2
(ja)
*
|
2018-07-18 |
2024-04-01 |
アムジエン・インコーポレーテツド |
Ｓｔｅａｐ１に対するキメラ受容体及びその使用方法
|
|
EP3844186A4
(en)
|
2018-08-29 |
2022-08-17 |
National University of Singapore |
METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS
|
|
WO2020056045A1
(en)
*
|
2018-09-13 |
2020-03-19 |
Nkarta, Inc. |
Natural killer cell compositions and immunotherapy methods for treating tumors
|
|
CN109096405B
(zh)
*
|
2018-09-20 |
2021-07-09 |
杭州普略生物科技有限公司 |
以gd2为靶点的嵌合抗原受体及药物组合物
|
|
EP3861854B1
(en)
*
|
2018-09-27 |
2025-01-22 |
Central Institute for Experimental Medicine and Life Science |
Immunodeficient mouse
|
|
SG11202104188VA
(en)
|
2018-11-01 |
2021-05-28 |
Juno Therapeutics Inc |
Methods for treatment using chimeric antigen receptors specific for b-cell maturation antigen
|
|
CA3117978A1
(en)
|
2018-11-08 |
2020-05-14 |
Juno Therapeutics, Inc. |
Methods and combinations for treatment and t cell modulation
|
|
CA3120563A1
(en)
|
2018-11-26 |
2020-06-04 |
Nkarta, Inc. |
Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
|
|
WO2020180882A1
(en)
|
2019-03-05 |
2020-09-10 |
Nkarta, Inc. |
Cd19-directed chimeric antigen receptors and uses thereof in immunotherapy
|
|
EP3964238A4
(en)
*
|
2019-05-07 |
2022-09-14 |
Gracell Biotechnologies (Shanghai) Co., Ltd. |
MANIPULATED IMMUNE CELL TARGETING BCMA AND USE THEREOF
|
|
DK3967329T3
(da)
*
|
2019-05-07 |
2026-05-11 |
Gracell Bioscience Shanghai Co Ltd |
Genmanipuleret immuncelle, der er målrettet mod bcma, og anvendelse deraf
|
|
CN113402612A
(zh)
|
2020-03-17 |
2021-09-17 |
西比曼生物科技（香港）有限公司 |
靶向cd19和cd20的联合嵌合抗原受体及其应用
|
|
CN111499763A
(zh)
*
|
2020-03-31 |
2020-08-07 |
江苏省省级机关医院 |
一种靶向mage-a1的特异性全人源嵌合抗原受体及其应用
|
|
JP2023522330A
(ja)
*
|
2020-04-17 |
2023-05-30 |
シティ・オブ・ホープ |
Ｆｌｔ３陽性悪性腫瘍を処置するためのｆｌｔ３標的化キメラ抗原受容体改変細胞
|
|
CN115461361B
(zh)
*
|
2020-05-08 |
2025-03-14 |
玛希敦大学 |
嵌合抗原受体和携带该受体的经修饰的细胞
|
|
BR112022022953A2
(pt)
*
|
2020-05-12 |
2023-03-21 |
Lyell Immunopharma Inc |
Espaçadores de receptores de antígenos quiméricos
|
|
MX2023002887A
(es)
|
2020-09-10 |
2023-08-16 |
Mustang Bio Inc |
Terapia combinada que comprende células t del receptor de antígenos quiméricos (car) dirigidas al cáncer y un método para utilizar las mismas para un tratamiento para el cáncer.
|
|
CN112111014A
(zh)
*
|
2020-09-22 |
2020-12-22 |
廖文强 |
一种抗氧化嵌合型抗原受体和免疫细胞
|
|
CN116848147A
(zh)
*
|
2020-11-20 |
2023-10-03 |
先声再明医药有限公司 |
Cd19人源化抗体及其应用
|
|
TW202237827A
(zh)
|
2020-12-03 |
2022-10-01 |
美商世紀治療股份有限公司 |
經基因工程改造之細胞及其用途
|
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
|
KR20230121129A
(ko)
*
|
2020-12-16 |
2023-08-17 |
오리온 코포레이션 |
Ｃａｒ ｔ 세포 기능을 향상시키는 키메라 항원 수용체(ｃａｒ)스페이서 변형
|
|
JP2024500847A
(ja)
|
2020-12-18 |
2024-01-10 |
センチュリー セラピューティクス，インコーポレイテッド |
適合可能な受容体特異性を有するキメラ抗原受容体システム
|
|
EP4314040A2
(en)
*
|
2021-03-30 |
2024-02-07 |
City of Hope |
Car t cell therapy and ifn gamma
|
|
EP4722239A2
(en)
*
|
2021-08-20 |
2026-04-08 |
Christopher E. Rudd |
Compositions and methods for anti-virus chimeric antigen receptor
|
|
CN115873126A
(zh)
*
|
2021-11-26 |
2023-03-31 |
深圳科兴药业有限公司 |
人生长激素融合蛋白及其制备和用途
|
|
CN117004604A
(zh)
*
|
2022-04-28 |
2023-11-07 |
南京北恒生物科技有限公司 |
一种ciita基因被敲除的工程化免疫细胞及其用途
|
|
WO2024026107A2
(en)
|
2022-07-28 |
2024-02-01 |
Lentigen Technology, Inc. |
Chimeric antigen receptor therapies for treating solid tumors
|
|
CN116254230A
(zh)
*
|
2022-09-14 |
2023-06-13 |
卡瑞济(北京)生命科技有限公司 |
用于制备和扩增通用型人源化抗cd19 car-nk细胞的方法及其用途
|
|
CN117942275A
(zh)
*
|
2022-10-31 |
2024-04-30 |
康码（上海）生物科技有限公司 |
一种基于病毒阻断剂的洗手液及其应用
|
|
WO2024118866A1
(en)
|
2022-12-01 |
2024-06-06 |
Modernatx, Inc. |
Gpc3-specific antibodies, binding domains, and related proteins and uses thereof
|
|
AU2024244733B2
(en)
|
2023-03-31 |
2025-12-11 |
AbelZeta Inc. |
Bispecific chimeric antigen receptors targeting cd20 and bcma
|
|
CN119101166A
(zh)
*
|
2023-06-08 |
2024-12-10 |
博生吉医药科技(苏州)有限公司 |
B7-H3嵌合抗原受体修饰的Vδ1 T细胞及其应用
|
|
WO2025064828A1
(en)
*
|
2023-09-20 |
2025-03-27 |
Kure.Ai, Inc. |
Methods and reagents to improve cell therapy with the creation of novel car-targeting mr1 protein
|