JP2017086090A5 - - Google Patents
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- Publication number
- JP2017086090A5 JP2017086090A5 JP2017032171A JP2017032171A JP2017086090A5 JP 2017086090 A5 JP2017086090 A5 JP 2017086090A5 JP 2017032171 A JP2017032171 A JP 2017032171A JP 2017032171 A JP2017032171 A JP 2017032171A JP 2017086090 A5 JP2017086090 A5 JP 2017086090A5
- Authority
- JP
- Japan
- Prior art keywords
- vlp
- chromatographic
- ion exchange
- contacting
- solution containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90682107P | 2007-03-14 | 2007-03-14 | |
| US60/906,821 | 2007-03-14 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013112580A Division JP2013176392A (ja) | 2007-03-14 | 2013-05-29 | ウイルス様粒子の精製 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019000688A Division JP2019068846A (ja) | 2007-03-14 | 2019-01-07 | ウイルス様粒子の精製 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017086090A JP2017086090A (ja) | 2017-05-25 |
| JP2017086090A5 true JP2017086090A5 (enExample) | 2017-11-02 |
Family
ID=39760420
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009553820A Active JP5284290B2 (ja) | 2007-03-14 | 2008-03-14 | ウイルス様粒子の精製 |
| JP2013112580A Pending JP2013176392A (ja) | 2007-03-14 | 2013-05-29 | ウイルス様粒子の精製 |
| JP2017032171A Pending JP2017086090A (ja) | 2007-03-14 | 2017-02-23 | ウイルス様粒子の精製 |
| JP2019000688A Pending JP2019068846A (ja) | 2007-03-14 | 2019-01-07 | ウイルス様粒子の精製 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009553820A Active JP5284290B2 (ja) | 2007-03-14 | 2008-03-14 | ウイルス様粒子の精製 |
| JP2013112580A Pending JP2013176392A (ja) | 2007-03-14 | 2013-05-29 | ウイルス様粒子の精製 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019000688A Pending JP2019068846A (ja) | 2007-03-14 | 2019-01-07 | ウイルス様粒子の精製 |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US8481693B2 (enExample) |
| EP (1) | EP2134360B1 (enExample) |
| JP (4) | JP5284290B2 (enExample) |
| KR (3) | KR20150098681A (enExample) |
| AU (1) | AU2008224877B2 (enExample) |
| CA (1) | CA2683977C (enExample) |
| DK (1) | DK2134360T3 (enExample) |
| ES (1) | ES2559421T3 (enExample) |
| HU (1) | HUE028605T2 (enExample) |
| PL (1) | PL2134360T3 (enExample) |
| SG (2) | SG10201701988TA (enExample) |
| WO (1) | WO2008113011A2 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2641613A1 (en) | 2006-09-29 | 2013-09-25 | Ligocyte Pharmaceuticals, Inc. | Liquid norovirus vaccine formulations comprising toll-like receptor (TLR) agonist as adjuvant |
| SG10201701988TA (en) | 2007-03-14 | 2017-04-27 | Ligocyte Pharmaceuticals Inc | Virus like particle purification |
| CN101918028B (zh) | 2007-09-18 | 2015-01-07 | 莱戈赛特医药股份有限公司 | 赋予针对诺如病毒的保护性免疫应答的疫苗 |
| US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| HUE028341T2 (en) * | 2009-06-16 | 2016-12-28 | Genzyme Corp | Improved methods for purification of recombinant aav vectors |
| EP2449096A4 (en) * | 2009-07-03 | 2014-01-08 | Univ Queensland | METHOD FOR PRODUCING A BIOLOGICAL PARTICLE STRUCTURE |
| US20110142863A1 (en) | 2009-12-16 | 2011-06-16 | Millipore Corporation | Flow through purification processes for large biomolecules |
| EP2524215B1 (en) | 2010-01-15 | 2018-12-26 | Bio-Rad Laboratories, Inc. | Surface neutralization of apatite |
| CN102985536B (zh) * | 2010-04-14 | 2017-12-05 | Emd密理博公司 | 生产高效价、高纯度的病毒母液的方法及使用其的方法 |
| DE102010046817A1 (de) * | 2010-09-28 | 2012-03-29 | Sartorius Stedim Biotech Gmbh | Verfahren zur Abtrennung von Viren aus einem Kontaminanten enthaltenden flüssigen Medium |
| FI122520B (fi) * | 2010-10-15 | 2012-03-15 | Vesna Blazevic | Noroviruksen kapsidi ja rotaviruksen VP6-proteiini käytettäväksi yhdistelmärokotteena |
| WO2012106449A1 (en) | 2011-02-02 | 2012-08-09 | Bio-Rad Laboratories, Inc. | Apatite surface neutralization with alkali solutions |
| MX356586B (es) | 2011-07-11 | 2018-06-05 | Takeda Vaccines Inc | Formulaciones parenterales de vacunas contra los norovirus. |
| EP2554664A1 (de) * | 2011-08-02 | 2013-02-06 | Life Science Inkubator | Verfahren zur Aufreinigung von Virus-ähnlichen Partikeln (VLP) |
| US9517261B2 (en) * | 2011-12-30 | 2016-12-13 | Deutsches Krebsforschungszentrum | Second generation virus-like particles (VLP) from Epstein-Barr viruses for vaccination purposes |
| US9815695B2 (en) | 2012-05-30 | 2017-11-14 | Bio-Rad Laboratories, Inc. | In situ restoration of apatite-based chromatography resins |
| JOP20130186B1 (ar) * | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
| KR20150118155A (ko) * | 2013-02-22 | 2015-10-21 | 에이전시 포 사이언스, 테크놀로지 앤드 리서치 | 음성 하전된 입자들을 갖는 바이러스 제제들의 크로마토그래피 정제 |
| JP6479305B2 (ja) | 2013-07-12 | 2019-03-06 | 株式会社Ｕｍｎファーマ | ウイルス様粒子の精製方法 |
| JP2015017065A (ja) * | 2013-07-12 | 2015-01-29 | 株式会社Ｕｍｎファーマ | ノロウイルスのウイルス様粒子を含む医薬組成物 |
| JP2015015931A (ja) * | 2013-07-12 | 2015-01-29 | 株式会社Ｕｍｎファーマ | ウイルス様粒子を含む培養物の製造方法 |
| CA2926225A1 (en) | 2013-10-03 | 2015-04-09 | Takeda Vaccines, Inc. | Methods of detection and removal of rhabdoviruses from cell lines |
| EP3157551B1 (en) | 2014-06-23 | 2023-02-15 | Bio-Rad Laboratories, Inc. | Apatite in-situ restoration |
| CN105392569B (zh) | 2014-06-23 | 2019-08-20 | 生物辐射实验室股份有限公司 | 磷灰石预处理 |
| CN107603959A (zh) * | 2017-08-30 | 2018-01-19 | 四川大学 | 提高缓冲液盐离子浓度纯化病毒的方法 |
| WO2019111057A1 (en) * | 2017-12-07 | 2019-06-13 | Emp Biotech Gmbh | System and method of applied radial technology chromatography |
| JP6704074B2 (ja) * | 2019-02-04 | 2020-06-03 | 株式会社Ｕｍｎファーマ | ウイルス様粒子の精製方法 |
| WO2021002257A1 (ja) * | 2019-07-04 | 2021-01-07 | 株式会社カネカ | ウイルスまたはウイルス様粒子の精製方法 |
| JPWO2022044727A1 (enExample) * | 2020-08-28 | 2022-03-03 | ||
| JP2023545998A (ja) * | 2020-10-05 | 2023-11-01 | ザルトリウス ビーアイエー セパレーションズ ディー．オー．オー． | 疎水性相互作用クロマトグラフィーによるｄｎａプラスミド調製物からのｒｎａ及び不純物の改善された除去 |
| JP7621392B2 (ja) * | 2021-02-02 | 2025-01-24 | 株式会社ニチモ | 太陽光発電システム |
| EP4340874A1 (en) | 2021-05-21 | 2024-03-27 | Takeda Vaccines, Inc. | Solid composition, freeze-drying method and glass vial |
| WO2025077800A1 (en) * | 2023-10-12 | 2025-04-17 | Chengdu Kanghua Biological Products Co., Ltd. | Purification of norovirus virus-like particles (vlps) |
| WO2025077807A1 (en) * | 2023-10-12 | 2025-04-17 | Chengdu Kanghua Biological Products Co., Ltd. | Methods for obtaining high-purity norovirus virus-like particles (vlps) |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2833106B2 (ja) | 1990-02-21 | 1998-12-09 | 株式会社島津製作所 | 液体クロマトグラフ |
| WO1994026087A2 (en) | 1993-05-14 | 1994-11-24 | Connor Kim C O | Recombinant protein production and insect cell culture and process |
| AU693203B2 (en) * | 1994-05-16 | 1998-06-25 | Merck Sharp & Dohme Corp. | Papillomavirus vaccines |
| AR004464A1 (es) * | 1994-11-14 | 1998-12-16 | Merck Sharp & Dohme | Un metodo para producir una proteina de capside de papilomavirus |
| JP3316325B2 (ja) | 1994-12-20 | 2002-08-19 | 富士シリシア化学株式会社 | ビール安定化処理用シリカゲル及びその製造方法並びにビールの安定化処理方法 |
| US5641870A (en) | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
| WO1998021338A1 (en) | 1996-11-08 | 1998-05-22 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Synthesis and purification of hepatitis c virus-like particles |
| AU742409B2 (en) | 1997-09-05 | 2002-01-03 | Medimmune, Llc | In vitro method for disassembly/reassembly of papillomavirus virus-like particles (VLPs) |
| DE19823814A1 (de) * | 1998-05-27 | 1999-12-02 | Octapharma Ag Ziegelbruecke | Verfahren zur Trennung und/oder Isolierung von Plasmaproteinen mit annularer Chromatographie |
| SK2232001A3 (en) * | 1998-08-14 | 2001-08-06 | Merck & Co Inc | Process for purifying human papillomavirus virus-like particles |
| US6349843B1 (en) | 1999-04-01 | 2002-02-26 | The Vollrath Company Llc | Pan removal ramp |
| ES2398413T3 (es) * | 1999-06-22 | 2013-03-19 | Japan As Represented By Director-General Of National Institute Of Infectious Diseases | Kit de detección de SRSV |
| DE10012732A1 (de) | 2000-03-18 | 2001-09-20 | Aventis Behring Gmbh | Thrombin-Zubereitungen und Verfahren zu ihrer Herstellung |
| JP2003066021A (ja) | 2001-08-28 | 2003-03-05 | Hiroshi Shionoya | 連続分取液体クロマトグラフィー装置とそれを用いる方法 |
| AU2003217413A1 (en) * | 2002-02-14 | 2003-09-04 | Novavax, Inc. | Method for isolation and purification of expressed gene products in vitro |
| DK1501369T3 (en) * | 2002-04-26 | 2015-09-28 | Genentech Inc | Non-affinity purification of proteins |
| CA2496918A1 (en) | 2002-08-28 | 2004-03-11 | Introgen Therapeutics Inc. | Chromatographic methods for adenovirus purification |
| US7879338B2 (en) * | 2003-07-21 | 2011-02-01 | Boyce Thompson Institute For Plant Research | Vectors and methods for immunization against norovirus using transgenic plants |
| US7481997B1 (en) * | 2004-02-12 | 2009-01-27 | Montana State University | Snow mountain virus genome sequence, virus-like particles and methods of use |
| US8277819B2 (en) * | 2005-06-16 | 2012-10-02 | Children's Hospital Medical Center | Norovirus particle for use as an antiviral or vaccine |
| EP1736538A1 (en) * | 2005-06-21 | 2006-12-27 | Cytos Biotechnology AG | Process for the preparative purification of virus-like-particles (VLPs) |
| US7527801B2 (en) | 2005-11-22 | 2009-05-05 | Novartis Vaccines And Diagnostics, Inc. | Norovirus and Sapovirus antigens |
| CN101389350B (zh) | 2005-12-29 | 2013-11-13 | 贝林格尔.英格海姆维特梅迪卡有限公司 | 多价pcv2免疫原性组合物和制备此类组合物的方法 |
| AU2007345768B2 (en) | 2006-07-27 | 2013-08-01 | Ligocyte Pharmaceuticals, Inc. | Chimeric influenza virus-like particles |
| EP2641613A1 (en) * | 2006-09-29 | 2013-09-25 | Ligocyte Pharmaceuticals, Inc. | Liquid norovirus vaccine formulations comprising toll-like receptor (TLR) agonist as adjuvant |
| US8202967B2 (en) | 2006-10-27 | 2012-06-19 | Boehringer Ingelheim Vetmedica, Inc. | H5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use |
| SG10201701988TA (en) | 2007-03-14 | 2017-04-27 | Ligocyte Pharmaceuticals Inc | Virus like particle purification |
| EP2027875A1 (en) | 2007-08-23 | 2009-02-25 | Octapharma AG | A Process for Isolation and Purification of a Target Protein free of Prion Protein (PrPSC) |
| CN101918028B (zh) | 2007-09-18 | 2015-01-07 | 莱戈赛特医药股份有限公司 | 赋予针对诺如病毒的保护性免疫应答的疫苗 |
| EP2235165A1 (en) | 2007-12-21 | 2010-10-06 | Cytos Biotechnology AG | Process for clarifying cell homogenates |
| EP2324113B8 (en) * | 2008-08-08 | 2018-04-04 | Takeda Vaccines, Inc. | Virus-like particles comprising composite capsid amino acid sequences for enhanced cross reactivity |
| US20110262483A1 (en) | 2008-11-03 | 2011-10-27 | Ligocyte Pharmaceuticals, Inc. | Methods for isolating enveloped virus-based vlps free of infectious agents |
| US8945895B2 (en) | 2009-07-31 | 2015-02-03 | Baxter International Inc. | Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof |
| KR20120125627A (ko) * | 2010-01-21 | 2012-11-16 | 리고사이트 파머슈티컬즈 인코퍼레이티드 | 칼리시바이러스 바이러스 유사 입자들 상에 표적화된 이종 항원 제공 |
| US9193760B2 (en) | 2010-09-20 | 2015-11-24 | Bio-Rad Laboratories, Inc. | Dissociation of product-complexed contaminants in chromatography |
| FI122520B (fi) | 2010-10-15 | 2012-03-15 | Vesna Blazevic | Noroviruksen kapsidi ja rotaviruksen VP6-proteiini käytettäväksi yhdistelmärokotteena |
| CN102260651A (zh) | 2011-06-24 | 2011-11-30 | 华中科技大学同济医学院附属协和医院 | 一种纯化病毒样颗粒蛋白的方法及其应用 |
| JOP20130186B1 (ar) | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
| JP2015015931A (ja) | 2013-07-12 | 2015-01-29 | 株式会社Ｕｍｎファーマ | ウイルス様粒子を含む培養物の製造方法 |
-
2008
- 2008-03-14 SG SG10201701988TA patent/SG10201701988TA/en unknown
- 2008-03-14 ES ES08782762.2T patent/ES2559421T3/es active Active
- 2008-03-14 US US12/531,248 patent/US8481693B2/en active Active
- 2008-03-14 PL PL08782762T patent/PL2134360T3/pl unknown
- 2008-03-14 KR KR1020157020558A patent/KR20150098681A/ko not_active Ceased
- 2008-03-14 CA CA2683977A patent/CA2683977C/en active Active
- 2008-03-14 EP EP08782762.2A patent/EP2134360B1/en active Active
- 2008-03-14 HU HUE08782762A patent/HUE028605T2/en unknown
- 2008-03-14 JP JP2009553820A patent/JP5284290B2/ja active Active
- 2008-03-14 DK DK08782762.2T patent/DK2134360T3/en active
- 2008-03-14 AU AU2008224877A patent/AU2008224877B2/en active Active
- 2008-03-14 KR KR1020167036031A patent/KR20170001720A/ko not_active Ceased
- 2008-03-14 KR KR1020097021421A patent/KR101576219B1/ko active Active
- 2008-03-14 WO PCT/US2008/057072 patent/WO2008113011A2/en not_active Ceased
- 2008-03-14 SG SG2012018131A patent/SG179488A1/en unknown
-
2013
- 2013-05-29 JP JP2013112580A patent/JP2013176392A/ja active Pending
- 2013-06-10 US US13/914,331 patent/US9359410B2/en active Active
-
2016
- 2016-05-02 US US15/144,265 patent/US10172930B2/en active Active
-
2017
- 2017-02-23 JP JP2017032171A patent/JP2017086090A/ja active Pending
-
2018
- 2018-12-07 US US16/213,297 patent/US10792353B2/en active Active
-
2019
- 2019-01-07 JP JP2019000688A patent/JP2019068846A/ja active Pending
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