JP2017086090A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017086090A5 JP2017086090A5 JP2017032171A JP2017032171A JP2017086090A5 JP 2017086090 A5 JP2017086090 A5 JP 2017086090A5 JP 2017032171 A JP2017032171 A JP 2017032171A JP 2017032171 A JP2017032171 A JP 2017032171A JP 2017086090 A5 JP2017086090 A5 JP 2017086090A5
- Authority
- JP
- Japan
- Prior art keywords
- vlp
- chromatographic
- ion exchange
- contacting
- solution containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90682107P | 2007-03-14 | 2007-03-14 | |
| US60/906,821 | 2007-03-14 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013112580A Division JP2013176392A (ja) | 2007-03-14 | 2013-05-29 | ウイルス様粒子の精製 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019000688A Division JP2019068846A (ja) | 2007-03-14 | 2019-01-07 | ウイルス様粒子の精製 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017086090A JP2017086090A (ja) | 2017-05-25 |
| JP2017086090A5 true JP2017086090A5 (enExample) | 2017-11-02 |
Family
ID=39760420
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009553820A Active JP5284290B2 (ja) | 2007-03-14 | 2008-03-14 | ウイルス様粒子の精製 |
| JP2013112580A Pending JP2013176392A (ja) | 2007-03-14 | 2013-05-29 | ウイルス様粒子の精製 |
| JP2017032171A Pending JP2017086090A (ja) | 2007-03-14 | 2017-02-23 | ウイルス様粒子の精製 |
| JP2019000688A Pending JP2019068846A (ja) | 2007-03-14 | 2019-01-07 | ウイルス様粒子の精製 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009553820A Active JP5284290B2 (ja) | 2007-03-14 | 2008-03-14 | ウイルス様粒子の精製 |
| JP2013112580A Pending JP2013176392A (ja) | 2007-03-14 | 2013-05-29 | ウイルス様粒子の精製 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019000688A Pending JP2019068846A (ja) | 2007-03-14 | 2019-01-07 | ウイルス様粒子の精製 |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US8481693B2 (enExample) |
| EP (1) | EP2134360B1 (enExample) |
| JP (4) | JP5284290B2 (enExample) |
| KR (3) | KR20150098681A (enExample) |
| AU (1) | AU2008224877B2 (enExample) |
| CA (1) | CA2683977C (enExample) |
| DK (1) | DK2134360T3 (enExample) |
| ES (1) | ES2559421T3 (enExample) |
| HU (1) | HUE028605T2 (enExample) |
| PL (1) | PL2134360T3 (enExample) |
| SG (2) | SG179488A1 (enExample) |
| WO (1) | WO2008113011A2 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2601969B1 (en) | 2006-09-29 | 2016-03-30 | Takeda Vaccines, Inc. | Norovirus vaccine formulations |
| CA2683977C (en) | 2007-03-14 | 2017-04-25 | Ligocyte Pharmaceuticals, Inc. | A method of norovirus virus-like particle purification comprising ion exchange chromatography |
| CN104740624B (zh) | 2007-09-18 | 2018-04-24 | 武田疫苗股份有限公司 | 赋予针对诺如病毒的保护性免疫应答的疫苗 |
| US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| JP5956331B2 (ja) * | 2009-06-16 | 2016-07-27 | ジェンザイム・コーポレーション | 組換えａａｖベクターの改良された精製方法 |
| EP2449096A4 (en) * | 2009-07-03 | 2014-01-08 | Univ Queensland | METHOD FOR PRODUCING A BIOLOGICAL PARTICLE STRUCTURE |
| US20110142863A1 (en) | 2009-12-16 | 2011-06-16 | Millipore Corporation | Flow through purification processes for large biomolecules |
| CA2787009C (en) | 2010-01-15 | 2018-04-03 | Bio-Rad Laboratories, Inc. | Surface neutralization of apatite |
| SG184833A1 (en) * | 2010-04-14 | 2012-11-29 | Emd Millipore Corp | Methods of producing high titer, high purity virus stocks and methods of use thereof |
| DE102010046817A1 (de) * | 2010-09-28 | 2012-03-29 | Sartorius Stedim Biotech Gmbh | Verfahren zur Abtrennung von Viren aus einem Kontaminanten enthaltenden flüssigen Medium |
| FI122520B (fi) * | 2010-10-15 | 2012-03-15 | Vesna Blazevic | Noroviruksen kapsidi ja rotaviruksen VP6-proteiini käytettäväksi yhdistelmärokotteena |
| JP5881744B2 (ja) | 2011-02-02 | 2016-03-09 | バイオ−ラッド ラボラトリーズ インコーポレーティッド | アルカリ溶液でのアパタイトの表面中和方法 |
| PH12014500093A1 (en) * | 2011-07-11 | 2014-03-17 | Takeda Vaccines Inc | Parenteral norovirus vaccine formulations |
| EP2554664A1 (de) * | 2011-08-02 | 2013-02-06 | Life Science Inkubator | Verfahren zur Aufreinigung von Virus-ähnlichen Partikeln (VLP) |
| EP2797626B1 (en) * | 2011-12-30 | 2019-07-03 | Deutsches Krebsforschungszentrum | Second generation virus-like particles (vlp) from epstein-barr viruses for vaccination purposes |
| US9815695B2 (en) | 2012-05-30 | 2017-11-14 | Bio-Rad Laboratories, Inc. | In situ restoration of apatite-based chromatography resins |
| JOP20130186B1 (ar) | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
| JP6320429B2 (ja) * | 2013-02-22 | 2018-05-09 | エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ | 負帯電粒子を用いるウイルス調製物のクロマトグラフィー精製 |
| JP2015015931A (ja) * | 2013-07-12 | 2015-01-29 | 株式会社Ｕｍｎファーマ | ウイルス様粒子を含む培養物の製造方法 |
| JP6479305B2 (ja) * | 2013-07-12 | 2019-03-06 | 株式会社Ｕｍｎファーマ | ウイルス様粒子の精製方法 |
| JP2015017065A (ja) * | 2013-07-12 | 2015-01-29 | 株式会社Ｕｍｎファーマ | ノロウイルスのウイルス様粒子を含む医薬組成物 |
| JP2016533172A (ja) | 2013-10-03 | 2016-10-27 | タケダ ワクチン，インコーポレイテッド | 細胞株からラブドウイルスを検出および除去する方法 |
| EP3157863B1 (en) | 2014-06-23 | 2023-06-21 | Bio-Rad Laboratories, Inc. | Apatite in-situ restoration |
| CN105392569B (zh) | 2014-06-23 | 2019-08-20 | 生物辐射实验室股份有限公司 | 磷灰石预处理 |
| CN107603959A (zh) * | 2017-08-30 | 2018-01-19 | 四川大学 | 提高缓冲液盐离子浓度纯化病毒的方法 |
| US11325104B2 (en) * | 2017-12-07 | 2022-05-10 | Emp Biotech Gmbh | System and method of applied radial technology chromatography |
| JP6704074B2 (ja) * | 2019-02-04 | 2020-06-03 | 株式会社Ｕｍｎファーマ | ウイルス様粒子の精製方法 |
| US20220364064A1 (en) * | 2019-07-04 | 2022-11-17 | Kaneka Corporation | Method for purifying virus or virus-like particle |
| EP4206329A4 (en) * | 2020-08-28 | 2024-11-20 | Kaneka Corporation | Method for purifying useful substance |
| JP2023545998A (ja) * | 2020-10-05 | 2023-11-01 | ザルトリウス ビーアイエー セパレーションズ ディー．オー．オー． | 疎水性相互作用クロマトグラフィーによるｄｎａプラスミド調製物からのｒｎａ及び不純物の改善された除去 |
| EP4290762A4 (en) * | 2021-02-02 | 2025-01-08 | Nichimo Corporation | SOLAR POWER GENERATION SYSTEM AND REFLECTOR FOR SOLAR POWER GENERATION SYSTEM |
| WO2022246323A1 (en) | 2021-05-21 | 2022-11-24 | Takeda Vaccines, Inc. | Solid composition, freeze-drying method and glass vial |
| WO2025077807A1 (en) * | 2023-10-12 | 2025-04-17 | Chengdu Kanghua Biological Products Co., Ltd. | Methods for obtaining high-purity norovirus virus-like particles (vlps) |
| WO2025077800A1 (en) * | 2023-10-12 | 2025-04-17 | Chengdu Kanghua Biological Products Co., Ltd. | Purification of norovirus virus-like particles (vlps) |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2833106B2 (ja) | 1990-02-21 | 1998-12-09 | 株式会社島津製作所 | 液体クロマトグラフ |
| WO1994026087A2 (en) | 1993-05-14 | 1994-11-24 | Connor Kim C O | Recombinant protein production and insect cell culture and process |
| ES2264126T3 (es) * | 1994-05-16 | 2006-12-16 | MERCK & CO., INC. | Vacunas contra el papilomavirus. |
| AR004464A1 (es) * | 1994-11-14 | 1998-12-16 | Merck Sharp & Dohme | Un metodo para producir una proteina de capside de papilomavirus |
| JP3316325B2 (ja) | 1994-12-20 | 2002-08-19 | 富士シリシア化学株式会社 | ビール安定化処理用シリカゲル及びその製造方法並びにビールの安定化処理方法 |
| US5641870A (en) | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
| JP4021493B2 (ja) | 1996-11-08 | 2007-12-12 | ザ ガヴァメント オブ ザ ユナイテッド ステイツ オブ アメリカ、レプリゼンテッド バイ ザ セクレタリー、 デパートメント オブ ヘルス アンド ヒューマン サーヴィスィズ | Ｃ型肝炎ウイルス様粒子の合成および精製 |
| AU742409B2 (en) * | 1997-09-05 | 2002-01-03 | Medimmune, Llc | In vitro method for disassembly/reassembly of papillomavirus virus-like particles (VLPs) |
| DE19823814A1 (de) | 1998-05-27 | 1999-12-02 | Octapharma Ag Ziegelbruecke | Verfahren zur Trennung und/oder Isolierung von Plasmaproteinen mit annularer Chromatographie |
| EP1105466B1 (en) * | 1998-08-14 | 2006-04-26 | Merck & Co., Inc. | Process for purifying human papillomavirus virus-like particles |
| US6349843B1 (en) | 1999-04-01 | 2002-02-26 | The Vollrath Company Llc | Pan removal ramp |
| CA2375337C (en) * | 1999-06-22 | 2012-09-25 | Naokazu Takeda | Srsv detection kit |
| DE10012732A1 (de) * | 2000-03-18 | 2001-09-20 | Aventis Behring Gmbh | Thrombin-Zubereitungen und Verfahren zu ihrer Herstellung |
| JP2003066021A (ja) | 2001-08-28 | 2003-03-05 | Hiroshi Shionoya | 連続分取液体クロマトグラフィー装置とそれを用いる方法 |
| WO2003068804A2 (en) * | 2002-02-14 | 2003-08-21 | Novavax, Inc. | Novel insect cell line |
| SI1501369T1 (sl) * | 2002-04-26 | 2015-10-30 | Genentech, Inc. | Neafinitetno čiščenje proteinov |
| US20040106184A1 (en) | 2002-08-28 | 2004-06-03 | Introgen Therapeutics Inc. | Chromatographic methods for adenovirus purification |
| US7879338B2 (en) * | 2003-07-21 | 2011-02-01 | Boyce Thompson Institute For Plant Research | Vectors and methods for immunization against norovirus using transgenic plants |
| US7481997B1 (en) * | 2004-02-12 | 2009-01-27 | Montana State University | Snow mountain virus genome sequence, virus-like particles and methods of use |
| US8277819B2 (en) * | 2005-06-16 | 2012-10-02 | Children's Hospital Medical Center | Norovirus particle for use as an antiviral or vaccine |
| EP1736538A1 (en) * | 2005-06-21 | 2006-12-27 | Cytos Biotechnology AG | Process for the preparative purification of virus-like-particles (VLPs) |
| WO2007081447A2 (en) * | 2005-11-22 | 2007-07-19 | Novartis Vaccines And Diagnostics, Inc. | Norovirus and sapovirus antigens |
| DK2275132T3 (da) | 2005-12-29 | 2021-05-17 | Boehringer Ingelheim Animal Health Usa Inc | Multivalente pcv2-immunogeniske sammensætninger og fremgangsmåder til at fremstille dem |
| EP2044198A4 (en) | 2006-07-27 | 2010-09-08 | Ligocyte Pharmaceuticals Inc | CHIMERIC INFLUENZA VIRUS TYPE PARTICLES |
| EP2601969B1 (en) * | 2006-09-29 | 2016-03-30 | Takeda Vaccines, Inc. | Norovirus vaccine formulations |
| US8202967B2 (en) | 2006-10-27 | 2012-06-19 | Boehringer Ingelheim Vetmedica, Inc. | H5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use |
| CA2683977C (en) | 2007-03-14 | 2017-04-25 | Ligocyte Pharmaceuticals, Inc. | A method of norovirus virus-like particle purification comprising ion exchange chromatography |
| EP2027875A1 (en) | 2007-08-23 | 2009-02-25 | Octapharma AG | A Process for Isolation and Purification of a Target Protein free of Prion Protein (PrPSC) |
| CN104740624B (zh) | 2007-09-18 | 2018-04-24 | 武田疫苗股份有限公司 | 赋予针对诺如病毒的保护性免疫应答的疫苗 |
| EP2235165A1 (en) | 2007-12-21 | 2010-10-06 | Cytos Biotechnology AG | Process for clarifying cell homogenates |
| JP5852883B2 (ja) * | 2008-08-08 | 2016-02-03 | タケダ ワクチン，インコーポレイテッド | 交差反応性の増強のための複合カプシドアミノ酸配列を含むウイルス様粒子 |
| WO2010062757A1 (en) | 2008-11-03 | 2010-06-03 | Ligocyte Pharmaceuticals, Inc. | Improved methods for isolating enveloped virus-based vlps free of infectious agents |
| US8945895B2 (en) | 2009-07-31 | 2015-02-03 | Baxter International Inc. | Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof |
| JP2013517773A (ja) * | 2010-01-21 | 2013-05-20 | リゴサイト ファーマスーティカルズ，インコーポレイテッド | カリシウイルスウイルス様粒子上の標的化異種抗原提示 |
| EP2619217B1 (en) | 2010-09-20 | 2016-11-09 | Bio-Rad Laboratories, Inc. | Dissociation of product-complexed contaminants in chromatography |
| FI122520B (fi) | 2010-10-15 | 2012-03-15 | Vesna Blazevic | Noroviruksen kapsidi ja rotaviruksen VP6-proteiini käytettäväksi yhdistelmärokotteena |
| CN102260651A (zh) | 2011-06-24 | 2011-11-30 | 华中科技大学同济医学院附属协和医院 | 一种纯化病毒样颗粒蛋白的方法及其应用 |
| JOP20130186B1 (ar) | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
| JP2015015931A (ja) | 2013-07-12 | 2015-01-29 | 株式会社Ｕｍｎファーマ | ウイルス様粒子を含む培養物の製造方法 |
-
2008
- 2008-03-14 CA CA2683977A patent/CA2683977C/en active Active
- 2008-03-14 HU HUE08782762A patent/HUE028605T2/en unknown
- 2008-03-14 ES ES08782762.2T patent/ES2559421T3/es active Active
- 2008-03-14 SG SG2012018131A patent/SG179488A1/en unknown
- 2008-03-14 SG SG10201701988TA patent/SG10201701988TA/en unknown
- 2008-03-14 KR KR1020157020558A patent/KR20150098681A/ko not_active Ceased
- 2008-03-14 JP JP2009553820A patent/JP5284290B2/ja active Active
- 2008-03-14 EP EP08782762.2A patent/EP2134360B1/en active Active
- 2008-03-14 AU AU2008224877A patent/AU2008224877B2/en active Active
- 2008-03-14 KR KR1020167036031A patent/KR20170001720A/ko not_active Ceased
- 2008-03-14 PL PL08782762T patent/PL2134360T3/pl unknown
- 2008-03-14 KR KR1020097021421A patent/KR101576219B1/ko active Active
- 2008-03-14 DK DK08782762.2T patent/DK2134360T3/en active
- 2008-03-14 WO PCT/US2008/057072 patent/WO2008113011A2/en not_active Ceased
- 2008-03-14 US US12/531,248 patent/US8481693B2/en active Active
-
2013
- 2013-05-29 JP JP2013112580A patent/JP2013176392A/ja active Pending
- 2013-06-10 US US13/914,331 patent/US9359410B2/en active Active
-
2016
- 2016-05-02 US US15/144,265 patent/US10172930B2/en active Active
-
2017
- 2017-02-23 JP JP2017032171A patent/JP2017086090A/ja active Pending
-
2018
- 2018-12-07 US US16/213,297 patent/US10792353B2/en active Active
-
2019
- 2019-01-07 JP JP2019000688A patent/JP2019068846A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2007532477A5 (enExample) | ||
| KR101569783B1 (ko) | 항체의 정제 방법 | |
| CA2683977C (en) | A method of norovirus virus-like particle purification comprising ion exchange chromatography | |
| CN105017412B (zh) | 一种从牛血清中分离高纯度牛血清白蛋白的方法 | |
| JP2012018171A5 (enExample) | ||
| CA2807617C (en) | Elution of proteins from hydroxyapatite resins without resin deterioration | |
| JP2013519652A (ja) | 単一ユニット抗体精製 | |
| JP2016519137A5 (enExample) | ||
| JP6665184B2 (ja) | 混床イオン交換吸着剤 | |
| CN102234332B (zh) | 一种重组人血白蛋白及其融合蛋白的分离纯化工艺 | |
| JP2015503524A5 (enExample) | ||
| JP2023537565A5 (enExample) | ||
| Wang et al. | Evaluation of mixed-mode chromatographic resins for separating IgG from serum albumin containing feedstock | |
| JP7526360B2 (ja) | マルチモーダル金属アフィニティー処理ａａｖカプシド | |
| JP7540667B2 (ja) | アデノウイルス精製の方法 | |
| CN104818254A (zh) | 离子交换色谱纯化口蹄疫灭活病毒抗原的方法 | |
| CN116234619A (zh) | 宿主细胞dna的金属亲和提取 | |
| Fan et al. | Directing membrane chromatography to manufacture α1-antitrypsin from human plasma fraction IV | |
| WO2020153390A1 (ja) | 活性炭材料を使用する工程を含む抗体精製方法 | |
| KR20170035980A (ko) | 항체의 정제 방법 | |
| JP6303379B2 (ja) | 抗体の精製方法 | |
| JP2023529187A (ja) | 混入ｄｎａをより効果的に除去するための、アデノ随伴ウイルスの精製の強化 | |
| JP2002541155A5 (enExample) | ||
| JP5389342B2 (ja) | 吸着担体及び吸着担体の製造方法 | |
| Iyer et al. | Flow-through purification of viruses-a novel approach to vaccine purification |