SG10201701988TA - Virus like particle purification - Google Patents
Virus like particle purificationInfo
- Publication number
- SG10201701988TA SG10201701988TA SG10201701988TA SG10201701988TA SG10201701988TA SG 10201701988T A SG10201701988T A SG 10201701988TA SG 10201701988T A SG10201701988T A SG 10201701988TA SG 10201701988T A SG10201701988T A SG 10201701988TA SG 10201701988T A SG10201701988T A SG 10201701988TA
- Authority
- SG
- Singapore
- Prior art keywords
- virus
- particle purification
- purification
- particle
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/02—Recovery or purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16023—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16051—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Virology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90682107P | 2007-03-14 | 2007-03-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201701988TA true SG10201701988TA (en) | 2017-04-27 |
Family
ID=39760420
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201701988TA SG10201701988TA (en) | 2007-03-14 | 2008-03-14 | Virus like particle purification |
| SG2012018131A SG179488A1 (en) | 2007-03-14 | 2008-03-14 | Virus like particle purification |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2012018131A SG179488A1 (en) | 2007-03-14 | 2008-03-14 | Virus like particle purification |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US8481693B2 (enExample) |
| EP (1) | EP2134360B1 (enExample) |
| JP (4) | JP5284290B2 (enExample) |
| KR (3) | KR20170001720A (enExample) |
| AU (1) | AU2008224877B2 (enExample) |
| CA (1) | CA2683977C (enExample) |
| DK (1) | DK2134360T3 (enExample) |
| ES (1) | ES2559421T3 (enExample) |
| HU (1) | HUE028605T2 (enExample) |
| PL (1) | PL2134360T3 (enExample) |
| SG (2) | SG10201701988TA (enExample) |
| WO (1) | WO2008113011A2 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2601970B1 (en) | 2006-09-29 | 2016-10-26 | Takeda Vaccines, Inc. | Norovirus vaccine formulations |
| EP2134360B1 (en) | 2007-03-14 | 2015-11-18 | Takeda Vaccines, Inc. | Virus like particle purification |
| US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| US10130696B2 (en) | 2007-09-18 | 2018-11-20 | Takeda Vaccines, Inc. | Method of conferring a protective immune response to norovirus |
| EP3067417B1 (en) | 2009-06-16 | 2018-07-25 | Genzyme Corporation | Improved methods for purification of recombinant aav vectors |
| WO2011000058A1 (en) * | 2009-07-03 | 2011-01-06 | The University Of Queensland | A method of preparation of a biological particulate structure |
| US20110142863A1 (en) * | 2009-12-16 | 2011-06-16 | Millipore Corporation | Flow through purification processes for large biomolecules |
| WO2011088225A1 (en) | 2010-01-15 | 2011-07-21 | Bio-Rad Laboratories, Inc. | Surface neutralization of apatite |
| KR101549296B1 (ko) * | 2010-04-14 | 2015-09-01 | 이엠디 밀리포어 코포레이션 | 고역가 고순도 바이러스 스톡의 생산 방법 및 이의 사용 방법 |
| DE102010046817A1 (de) * | 2010-09-28 | 2012-03-29 | Sartorius Stedim Biotech Gmbh | Verfahren zur Abtrennung von Viren aus einem Kontaminanten enthaltenden flüssigen Medium |
| FI122520B (fi) * | 2010-10-15 | 2012-03-15 | Vesna Blazevic | Noroviruksen kapsidi ja rotaviruksen VP6-proteiini käytettäväksi yhdistelmärokotteena |
| WO2012106449A1 (en) | 2011-02-02 | 2012-08-09 | Bio-Rad Laboratories, Inc. | Apatite surface neutralization with alkali solutions |
| BR112014000656A2 (pt) * | 2011-07-11 | 2017-02-14 | Takeda Vaccines Inc | formulações de vacina parenteral contra norovírus |
| EP2554664A1 (de) * | 2011-08-02 | 2013-02-06 | Life Science Inkubator | Verfahren zur Aufreinigung von Virus-ähnlichen Partikeln (VLP) |
| EP2797626B1 (en) * | 2011-12-30 | 2019-07-03 | Deutsches Krebsforschungszentrum | Second generation virus-like particles (vlp) from epstein-barr viruses for vaccination purposes |
| CN104507952B (zh) * | 2012-05-30 | 2018-08-10 | 生物辐射实验室股份有限公司 | 基于磷灰石的色谱树脂的原位恢复 |
| JOP20130186B1 (ar) | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
| SG11201505190VA (en) * | 2013-02-22 | 2015-08-28 | Agency Science Tech & Res | Chromatographic purification of virus preparations with negatively charged particles |
| JP6479305B2 (ja) * | 2013-07-12 | 2019-03-06 | 株式会社Ｕｍｎファーマ | ウイルス様粒子の精製方法 |
| JP2015015931A (ja) * | 2013-07-12 | 2015-01-29 | 株式会社Ｕｍｎファーマ | ウイルス様粒子を含む培養物の製造方法 |
| JP2015017065A (ja) * | 2013-07-12 | 2015-01-29 | 株式会社Ｕｍｎファーマ | ノロウイルスのウイルス様粒子を含む医薬組成物 |
| CN106103720A (zh) | 2013-10-03 | 2016-11-09 | 武田疫苗股份有限公司 | 自细胞系检测和除去弹状病毒的方法 |
| CN105392569B (zh) | 2014-06-23 | 2019-08-20 | 生物辐射实验室股份有限公司 | 磷灰石预处理 |
| WO2015200278A1 (en) | 2014-06-23 | 2015-12-30 | Bio-Rad Laboratories, Inc. | Apatite in-situ restoration |
| CN107603959A (zh) * | 2017-08-30 | 2018-01-19 | 四川大学 | 提高缓冲液盐离子浓度纯化病毒的方法 |
| KR20250077599A (ko) * | 2017-12-07 | 2025-05-30 | 이엠피 바이오테크 게엠베하 | 응용 방사형 기술 크로마토그래피의 시스템 및 방법 |
| JP6704074B2 (ja) * | 2019-02-04 | 2020-06-03 | 株式会社Ｕｍｎファーマ | ウイルス様粒子の精製方法 |
| CN114008067B (zh) * | 2019-07-04 | 2025-08-05 | 株式会社钟化 | 病毒或病毒样颗粒的纯化方法 |
| WO2022044727A1 (ja) * | 2020-08-28 | 2022-03-03 | 株式会社カネカ | 有用物質の精製方法 |
| CN116348598A (zh) * | 2020-10-05 | 2023-06-27 | 赛多利斯比亚分离有限责任公司 | 通过疏水相互作用色谱法改善dna质粒制剂中rna和污染物的去除 |
| AU2022217587A1 (en) * | 2021-02-02 | 2023-08-17 | C. I. TAKIRON Corporation | Solar power generation system and reflector for solar power generation system |
| WO2022246323A1 (en) | 2021-05-21 | 2022-11-24 | Takeda Vaccines, Inc. | Solid composition, freeze-drying method and glass vial |
| WO2025077807A1 (en) * | 2023-10-12 | 2025-04-17 | Chengdu Kanghua Biological Products Co., Ltd. | Methods for obtaining high-purity norovirus virus-like particles (vlps) |
| WO2025077800A1 (en) * | 2023-10-12 | 2025-04-17 | Chengdu Kanghua Biological Products Co., Ltd. | Purification of norovirus virus-like particles (vlps) |
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| JP2833106B2 (ja) | 1990-02-21 | 1998-12-09 | 株式会社島津製作所 | 液体クロマトグラフ |
| WO1994026087A2 (en) | 1993-05-14 | 1994-11-24 | Connor Kim C O | Recombinant protein production and insect cell culture and process |
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| DE19823814A1 (de) | 1998-05-27 | 1999-12-02 | Octapharma Ag Ziegelbruecke | Verfahren zur Trennung und/oder Isolierung von Plasmaproteinen mit annularer Chromatographie |
| DK1105466T3 (da) * | 1998-08-14 | 2006-08-14 | Merck & Co Inc | Fremgangsmåde til oprensning af humant papillomvirus-viruslignende partikler |
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| AU2003213060A1 (en) * | 2002-02-14 | 2003-09-04 | Novavax, Inc. | Optimization of gene sequences of chimeric virus-like particles for expression in insect cells |
| CA2478925C (en) | 2002-04-26 | 2016-06-07 | Robert Lee Fahrner | Non-affinity purification of proteins |
| AU2003268210A1 (en) | 2002-08-28 | 2004-03-19 | Introgen Therapeutics Inc. | Chromatographic methods for adenovirus purification |
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| US7481997B1 (en) * | 2004-02-12 | 2009-01-27 | Montana State University | Snow mountain virus genome sequence, virus-like particles and methods of use |
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| EP1736538A1 (en) * | 2005-06-21 | 2006-12-27 | Cytos Biotechnology AG | Process for the preparative purification of virus-like-particles (VLPs) |
| JP5215865B2 (ja) * | 2005-11-22 | 2013-06-19 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド | ノロウイルス抗原およびサポウイルス抗原 |
| PT3320919T (pt) | 2005-12-29 | 2020-09-03 | Boehringer Ingelheim Animal Health Usa Inc | Composições imunogénicas de pcv2 multivalentes e métodos para produzir composições deste tipo |
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| EP2601970B1 (en) | 2006-09-29 | 2016-10-26 | Takeda Vaccines, Inc. | Norovirus vaccine formulations |
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| EP2134360B1 (en) | 2007-03-14 | 2015-11-18 | Takeda Vaccines, Inc. | Virus like particle purification |
| EP2027875A1 (en) | 2007-08-23 | 2009-02-25 | Octapharma AG | A Process for Isolation and Purification of a Target Protein free of Prion Protein (PrPSC) |
| US10130696B2 (en) | 2007-09-18 | 2018-11-20 | Takeda Vaccines, Inc. | Method of conferring a protective immune response to norovirus |
| EP2235165A1 (en) | 2007-12-21 | 2010-10-06 | Cytos Biotechnology AG | Process for clarifying cell homogenates |
| ES2668836T3 (es) * | 2008-08-08 | 2018-05-22 | Takeda Vaccines, Inc. | Partículas similivíricas que comprenden secuencias de aminoácidos de la cápside compuestas para reactividad cruzada potenciada |
| AU2009319979B2 (en) | 2008-11-03 | 2016-10-20 | Takeda Vaccines, Inc. | Improved methods for isolating enveloped virus-based VLPs free of infectious agents |
| US8945895B2 (en) | 2009-07-31 | 2015-02-03 | Baxter International Inc. | Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof |
| CN102791286B (zh) * | 2010-01-21 | 2017-08-08 | 莱戈赛特医药股份有限公司 | 杯状病毒病毒样颗粒上靶定异源抗原的呈递 |
| JP5903101B2 (ja) | 2010-09-20 | 2016-04-13 | バイオ−ラッド ラボラトリーズ インコーポレーティッド | クロマトグラフィーにおける生成物と複合体形成した夾雑物の分離方法 |
| FI122520B (fi) | 2010-10-15 | 2012-03-15 | Vesna Blazevic | Noroviruksen kapsidi ja rotaviruksen VP6-proteiini käytettäväksi yhdistelmärokotteena |
| CN102260651A (zh) | 2011-06-24 | 2011-11-30 | 华中科技大学同济医学院附属协和医院 | 一种纯化病毒样颗粒蛋白的方法及其应用 |
| JOP20130186B1 (ar) | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
| JP2015015931A (ja) | 2013-07-12 | 2015-01-29 | 株式会社Ｕｍｎファーマ | ウイルス様粒子を含む培養物の製造方法 |
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2008
- 2008-03-14 EP EP08782762.2A patent/EP2134360B1/en active Active
- 2008-03-14 KR KR1020167036031A patent/KR20170001720A/ko not_active Ceased
- 2008-03-14 PL PL08782762T patent/PL2134360T3/pl unknown
- 2008-03-14 DK DK08782762.2T patent/DK2134360T3/en active
- 2008-03-14 HU HUE08782762A patent/HUE028605T2/en unknown
- 2008-03-14 JP JP2009553820A patent/JP5284290B2/ja active Active
- 2008-03-14 AU AU2008224877A patent/AU2008224877B2/en active Active
- 2008-03-14 SG SG10201701988TA patent/SG10201701988TA/en unknown
- 2008-03-14 KR KR1020097021421A patent/KR101576219B1/ko active Active
- 2008-03-14 CA CA2683977A patent/CA2683977C/en active Active
- 2008-03-14 SG SG2012018131A patent/SG179488A1/en unknown
- 2008-03-14 WO PCT/US2008/057072 patent/WO2008113011A2/en not_active Ceased
- 2008-03-14 ES ES08782762.2T patent/ES2559421T3/es active Active
- 2008-03-14 US US12/531,248 patent/US8481693B2/en active Active
- 2008-03-14 KR KR1020157020558A patent/KR20150098681A/ko not_active Ceased
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2013
- 2013-05-29 JP JP2013112580A patent/JP2013176392A/ja active Pending
- 2013-06-10 US US13/914,331 patent/US9359410B2/en active Active
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2016
- 2016-05-02 US US15/144,265 patent/US10172930B2/en active Active
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2017
- 2017-02-23 JP JP2017032171A patent/JP2017086090A/ja active Pending
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2018
- 2018-12-07 US US16/213,297 patent/US10792353B2/en active Active
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2019
- 2019-01-07 JP JP2019000688A patent/JP2019068846A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2134360A4 (en) | 2011-08-24 |
| WO2008113011A2 (en) | 2008-09-18 |
| KR20150098681A (ko) | 2015-08-28 |
| AU2008224877B2 (en) | 2013-07-11 |
| DK2134360T3 (en) | 2016-02-22 |
| CA2683977C (en) | 2017-04-25 |
| US20100150961A1 (en) | 2010-06-17 |
| EP2134360A2 (en) | 2009-12-23 |
| JP2013176392A (ja) | 2013-09-09 |
| ES2559421T3 (es) | 2016-02-12 |
| US10172930B2 (en) | 2019-01-08 |
| KR101576219B1 (ko) | 2015-12-10 |
| US10792353B2 (en) | 2020-10-06 |
| JP2017086090A (ja) | 2017-05-25 |
| HK1138795A1 (zh) | 2010-09-03 |
| HUE028605T2 (en) | 2016-12-28 |
| US20190282686A1 (en) | 2019-09-19 |
| EP2134360B1 (en) | 2015-11-18 |
| JP5284290B2 (ja) | 2013-09-11 |
| US20160317645A1 (en) | 2016-11-03 |
| KR20170001720A (ko) | 2017-01-04 |
| US9359410B2 (en) | 2016-06-07 |
| US8481693B2 (en) | 2013-07-09 |
| CA2683977A1 (en) | 2008-09-18 |
| US20130344107A1 (en) | 2013-12-26 |
| KR20100015562A (ko) | 2010-02-12 |
| PL2134360T3 (pl) | 2016-05-31 |
| AU2008224877A1 (en) | 2008-09-18 |
| JP2010530734A (ja) | 2010-09-16 |
| JP2019068846A (ja) | 2019-05-09 |
| SG179488A1 (en) | 2012-04-27 |
| WO2008113011A3 (en) | 2008-12-24 |
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