JP2017060473A5 - - Google Patents
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- Publication number
- JP2017060473A5 JP2017060473A5 JP2016191501A JP2016191501A JP2017060473A5 JP 2017060473 A5 JP2017060473 A5 JP 2017060473A5 JP 2016191501 A JP2016191501 A JP 2016191501A JP 2016191501 A JP2016191501 A JP 2016191501A JP 2017060473 A5 JP2017060473 A5 JP 2017060473A5
- Authority
- JP
- Japan
- Prior art keywords
- immunogenic composition
- porcine
- circovirus
- porcine circovirus
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims description 32
- 241000202347 Porcine circovirus Species 0.000 claims description 28
- 230000002163 immunogen Effects 0.000 claims description 22
- 238000000034 method Methods 0.000 claims description 22
- 241000282898 Sus scrofa Species 0.000 claims description 20
- 244000005700 microbiome Species 0.000 claims description 16
- 241001533384 Circovirus Species 0.000 claims description 11
- 241000702619 Porcine parvovirus Species 0.000 claims description 11
- 230000001717 pathogenic effect Effects 0.000 claims description 11
- 241001135989 Porcine reproductive and respiratory syndrome virus Species 0.000 claims description 10
- 101710167800 Capsid assembly scaffolding protein Proteins 0.000 claims description 9
- 101710113540 ORF2 protein Proteins 0.000 claims description 9
- 101710090523 Putative movement protein Proteins 0.000 claims description 9
- 241000700605 Viruses Species 0.000 claims description 9
- 241000606860 Pasteurella Species 0.000 claims description 8
- 244000052769 pathogen Species 0.000 claims description 8
- 241000606748 Actinobacillus pleuropneumoniae Species 0.000 claims description 7
- 241000204045 Mycoplasma hyopneumoniae Species 0.000 claims description 7
- 208000015181 infectious disease Diseases 0.000 claims description 7
- 241000588807 Bordetella Species 0.000 claims description 6
- 208000005577 Gastroenteritis Diseases 0.000 claims description 6
- 241000606807 Glaesserella parasuis Species 0.000 claims description 6
- 208000005342 Porcine Reproductive and Respiratory Syndrome Diseases 0.000 claims description 6
- 241000725681 Swine influenza virus Species 0.000 claims description 6
- 239000000427 antigen Substances 0.000 claims description 6
- 102000036639 antigens Human genes 0.000 claims description 6
- 108091007433 antigens Proteins 0.000 claims description 6
- 230000002458 infectious effect Effects 0.000 claims description 6
- 230000000241 respiratory effect Effects 0.000 claims description 6
- 241001673669 Porcine circovirus 2 Species 0.000 claims description 5
- 241000282887 Suidae Species 0.000 claims description 5
- 208000010399 Wasting Syndrome Diseases 0.000 claims description 5
- 241000711573 Coronaviridae Species 0.000 claims description 4
- 241000589902 Leptospira Species 0.000 claims description 4
- 241000702670 Rotavirus Species 0.000 claims description 4
- 241000607142 Salmonella Species 0.000 claims description 4
- 241000194021 Streptococcus suis Species 0.000 claims description 4
- 239000002671 adjuvant Substances 0.000 claims description 4
- 229940087586 escherichia coli antigen Drugs 0.000 claims description 4
- 230000002238 attenuated effect Effects 0.000 claims description 3
- 230000028993 immune response Effects 0.000 claims description 3
- 210000000056 organ Anatomy 0.000 claims description 3
- 239000002574 poison Substances 0.000 claims description 3
- 231100000614 poison Toxicity 0.000 claims description 3
- 208000009305 pseudorabies Diseases 0.000 claims description 3
- 206010008631 Cholera Diseases 0.000 claims description 2
- 241000588724 Escherichia coli Species 0.000 claims description 2
- 241001138501 Salmonella enterica Species 0.000 claims description 2
- 208000036142 Viral infection Diseases 0.000 claims description 2
- 230000003053 immunization Effects 0.000 claims description 2
- 230000001850 reproductive effect Effects 0.000 claims description 2
- 208000011580 syndromic disease Diseases 0.000 claims description 2
- 230000009385 viral infection Effects 0.000 claims description 2
- 230000001364 causal effect Effects 0.000 claims 2
- 210000002345 respiratory system Anatomy 0.000 claims 1
- 208000023504 respiratory system disease Diseases 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 description 28
- 102000039446 nucleic acids Human genes 0.000 description 28
- 150000007523 nucleic acids Chemical class 0.000 description 28
- 102000004169 proteins and genes Human genes 0.000 description 14
- 108090000623 proteins and genes Proteins 0.000 description 10
- 210000001519 tissue Anatomy 0.000 description 9
- 241000124008 Mammalia Species 0.000 description 5
- 108091005461 Nucleic proteins Proteins 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 210000001165 lymph node Anatomy 0.000 description 3
- 241000588779 Bordetella bronchiseptica Species 0.000 description 2
- 241000606856 Pasteurella multocida Species 0.000 description 2
- 239000002773 nucleotide Substances 0.000 description 2
- 125000003729 nucleotide group Chemical group 0.000 description 2
- 229940051027 pasteurella multocida Drugs 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 101710098119 Chaperonin GroEL 2 Proteins 0.000 description 1
- 241000588722 Escherichia Species 0.000 description 1
- 241000606790 Haemophilus Species 0.000 description 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- 241000125945 Protoparvovirus Species 0.000 description 1
- 241000700638 Raccoonpox virus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 210000000621 bronchi Anatomy 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 231100000676 disease causative agent Toxicity 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 210000002741 palatine tonsil Anatomy 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 210000001913 submandibular gland Anatomy 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1589407P | 2007-12-21 | 2007-12-21 | |
| US61/015,894 | 2007-12-21 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010539780A Division JP2011507522A (ja) | 2007-12-21 | 2008-12-18 | 豚サーコウイルスに対してブタを免疫化するための方法および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017060473A JP2017060473A (ja) | 2017-03-30 |
| JP2017060473A5 true JP2017060473A5 (enExample) | 2017-06-22 |
Family
ID=40436491
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010539780A Pending JP2011507522A (ja) | 2007-12-21 | 2008-12-18 | 豚サーコウイルスに対してブタを免疫化するための方法および組成物 |
| JP2016191501A Pending JP2017060473A (ja) | 2007-12-21 | 2016-09-29 | 豚サーコウイルスに対してブタを免疫化するための方法および組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010539780A Pending JP2011507522A (ja) | 2007-12-21 | 2008-12-18 | 豚サーコウイルスに対してブタを免疫化するための方法および組成物 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20090162398A1 (enExample) |
| EP (1) | EP2225367A1 (enExample) |
| JP (2) | JP2011507522A (enExample) |
| KR (1) | KR20100094587A (enExample) |
| CN (1) | CN101932700A (enExample) |
| AR (1) | AR069882A1 (enExample) |
| AU (1) | AU2008343172B2 (enExample) |
| BR (1) | BRPI0821286A8 (enExample) |
| CA (1) | CA2710247C (enExample) |
| CL (1) | CL2008003813A1 (enExample) |
| CO (1) | CO6290791A2 (enExample) |
| ME (1) | ME01156B (enExample) |
| NZ (1) | NZ586238A (enExample) |
| RU (1) | RU2493254C9 (enExample) |
| UA (1) | UA99495C2 (enExample) |
| WO (1) | WO2009085912A1 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR078253A1 (es) | 2009-09-02 | 2011-10-26 | Boehringer Ingelheim Vetmed | Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad |
| CN102711816A (zh) * | 2009-10-22 | 2012-10-03 | 莱比锡大学 | 患有牛新生儿全血细胞减少症的小牛中的圆环病毒的检测 |
| EP2528931A4 (en) * | 2010-01-25 | 2013-12-04 | Blood Systems Inc | CYCLOVIRUS AND USE METHOD THEREFOR |
| HRP20200258T1 (hr) | 2010-03-16 | 2020-09-04 | Virginia Tech Intellectual Properties Inc | Živo atenuirano himerno cjepivo protiv svinjskog cirkovirusa |
| CA2804604C (en) * | 2010-07-08 | 2023-10-03 | United Biomedical, Inc. | Designer peptide-based pcv2 vaccine |
| CN101920012B (zh) * | 2010-07-22 | 2012-12-12 | 普莱柯生物工程股份有限公司 | 利用家蚕生物反应器生产猪圆环病毒2型重组衣壳蛋白亚单位疫苗的方法及其产品 |
| KR101030792B1 (ko) * | 2010-09-16 | 2011-04-27 | 주식회사 코미팜 | 돼지 써코바이러스２(ｐｃｖ２) 유전자의 표면발현용 벡터 및 이로 형질전환된 살모넬라 백신 균주 |
| CN102199571B (zh) * | 2011-04-06 | 2013-07-31 | 华中农业大学 | 一种表达猪2型圆环病毒orf2基因片段的重组支气管败血波氏杆菌株、疫苗及应用 |
| CN102988978B (zh) * | 2011-08-01 | 2016-02-03 | 普莱柯生物工程股份有限公司 | 含有猪圆环病毒2型抗原与副猪嗜血杆菌抗原的疫苗组合物及其制备方法与应用 |
| HUP1100470A2 (en) | 2011-08-30 | 2013-03-28 | Mezoegazdasagi Biotechnologiai Kutatokoezpont | Nanoparticle-based veterinary vaccine |
| EP2564869A1 (en) | 2011-09-02 | 2013-03-06 | Ceva Sante Animale | Synthetic capsid proteins and uses thereof |
| CN103083655B (zh) * | 2011-11-02 | 2015-08-26 | 普莱柯生物工程股份有限公司 | 预防和治疗猪圆环病毒2型、副猪嗜血杆菌和猪肺炎支原体感染的疫苗组合物及其制备方法 |
| CN102517331A (zh) * | 2011-12-26 | 2012-06-27 | 武汉中博生物股份有限公司 | 一种猪圆环病毒2型亚单位疫苗及其制备方法和其应用 |
| CN103033622B (zh) * | 2011-12-26 | 2015-03-25 | 武汉中博生物股份有限公司 | 猪圆环病毒2型elisa抗原检测试剂盒及其制备方法和其应用 |
| US9474692B2 (en) | 2012-01-13 | 2016-10-25 | Boehringer Ingelheim Vetmedica Gmbh | Kit for the preparation of a vaccinating agent |
| CN104735977B (zh) | 2012-06-12 | 2016-09-21 | 替代基因表达公司 | 用于在宿主细胞中表达重组蛋白的杆状病毒dna元件 |
| JP6364007B2 (ja) | 2012-08-17 | 2018-07-25 | インターベット インターナショナル ベー． フェー． | 不活化レプトスピラ細菌の免疫原性組成物 |
| CN102824634B (zh) * | 2012-09-14 | 2014-03-19 | 范红结 | 表达猪圆环病毒2型Cap蛋白的重组猪痘病毒载体疫苗及其制备方法 |
| CN103920146A (zh) * | 2013-01-14 | 2014-07-16 | 普莱柯生物工程股份有限公司 | 猪圆环病毒ⅱ型与猪伪狂犬病二联疫苗及其制备方法和应用 |
| BR102013001893B1 (pt) * | 2013-01-25 | 2022-01-25 | Fundação De Amparo À Pesquisa Do Estado De Minas Gerais - Fapemig | Antígenos recombinantes do porcine circovirus 2 (pcv-2) para formulações vacinais, kit de diagnóstico e uso |
| EP2789346A1 (en) | 2013-04-11 | 2014-10-15 | CEVA Santé Animale SA | Fusion polypeptides and vaccines |
| CN103275938B (zh) * | 2013-05-07 | 2015-02-25 | 上海市农业科学院 | 猪圆环病毒弱毒疫苗株的制备方法 |
| DK2994162T3 (en) | 2013-05-08 | 2021-06-21 | Pharmgate Biologics Inc | Vaccine for pcv2 og mycoplasma |
| EP3035958B1 (en) | 2013-08-23 | 2022-10-26 | Boehringer Ingelheim Animal Health USA Inc. | Porcine circovirus type 2 (pcv2) subunit vaccine |
| RU2662685C2 (ru) * | 2013-09-25 | 2018-07-26 | Зоэтис Сервисиз Ллс | Pcv2b дивергентная вакцинная композиция и способы её применения |
| KR20220083861A (ko) | 2013-10-02 | 2022-06-20 | 베링거 인겔하임 애니멀 헬스 유에스에이 인크. | Ｐｃｖ2 ｏｒｆ2 단백질 변이체 및 이로 이루어진 바이러스 유사 입자 |
| CN104248759B (zh) * | 2013-11-19 | 2017-05-10 | 普莱柯生物工程股份有限公司 | 一种疫苗组合物及其制备方法和应用 |
| CN104250640A (zh) | 2014-08-22 | 2014-12-31 | 普莱柯生物工程股份有限公司 | 猪伪狂犬病病毒基因缺失株、疫苗组合物及其制备方法和应用 |
| CN105709220B (zh) * | 2014-12-03 | 2020-03-31 | 普莱柯生物工程股份有限公司 | 用于猪圆环病毒与猪流感的疫苗组合物及制备方法和应用 |
| EP3034609A1 (en) | 2014-12-19 | 2016-06-22 | Ceva Sante Animale | Recombinant swinepox virus and vaccines |
| CN104984335A (zh) * | 2015-07-14 | 2015-10-21 | 浙江诺倍威生物技术有限公司 | 猪圆环病毒双亚型orf2共表达载体构建及疫苗制备 |
| JP7088835B2 (ja) * | 2015-10-16 | 2022-06-21 | カンザス ステイト ユニバーシティ リサーチ ファウンデーション | ブタサーコウイルス３型免疫原性組成物、その製造方法、およびその使用方法 |
| MY191905A (en) * | 2015-12-28 | 2022-07-18 | Boehringer Ingelheim Animal Health Usa Inc | M hyo multivalent vaccine and uses thereof |
| CN105785037B (zh) * | 2016-03-30 | 2017-09-19 | 中国农业科学院兰州兽医研究所 | 猪圆环病毒2型抗体快速检测层析试纸条及制备方法 |
| EP3254692A1 (en) | 2016-06-10 | 2017-12-13 | Ceva Sante Animale | Multivalent recombinant spv |
| CN106435016B (zh) * | 2016-08-30 | 2019-07-26 | 中国农业科学院兰州兽医研究所 | 一种快速显色一步法检测猪圆环病毒2型的lamp试剂盒 |
| CN107937354A (zh) * | 2017-11-10 | 2018-04-20 | 南京天邦生物科技有限公司 | 2型猪圆环病毒及其应用 |
| US20200390878A1 (en) | 2017-12-08 | 2020-12-17 | Ceva Sante Animale | Recombinant swinepox virus and vaccines |
| KR102133632B1 (ko) * | 2018-03-29 | 2020-07-13 | 충남대학교산학협력단 | 재조합 돼지 써코바이러스 및 이를 포함하는 돼지 써코바이러스 감염 질환의 예방용 백신 조성물 |
| JP2021527073A (ja) | 2018-06-11 | 2021-10-11 | セヴァ サンテ アニマレＣｅｖａ Ｓａｎｔｅ Ａｎｉｍａｌｅ | ブタサーコウイルスに対するワクチン接種 |
| CN109381696A (zh) * | 2018-08-27 | 2019-02-26 | 长沙创西生物科技有限公司 | 一种用于防治猪圆环病毒病的缓释微囊的制备方法 |
| CN111088396A (zh) * | 2019-11-14 | 2020-05-01 | 河南科技学院 | 一种同时检测副猪嗜血杆菌、猪细小病毒、猪圆环病毒2型的三重实时荧光pcr方法 |
| RU2747468C1 (ru) * | 2020-06-23 | 2021-05-05 | Федеральное Казенное Предприятие "Щелковский Биокомбинат" | Способ получения вакцины против цирковируса свиней (варианты) |
| CN113907044A (zh) * | 2021-11-09 | 2022-01-11 | 福建省连江县刘氏兔业养殖场 | 一种抗病猪品系的培育方法及其应用 |
| CN115820840A (zh) * | 2022-11-23 | 2023-03-21 | 武汉轻工大学 | 一种副猪嗜血杆菌感染后引起仔猪免疫抑制的分子标记物 |
| US20250332242A1 (en) | 2024-04-30 | 2025-10-30 | Zoetis Services Llc | Porcine endogenous retrovirus (perv)-free porcine circovirus type 2d-based vaccines and methods of use |
| US20250332243A1 (en) | 2024-04-30 | 2025-10-30 | Zoetis Services Llc | Methods of manufacturing porcine endogenous retrovirus (perv) free animal health vaccines |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4708871A (en) * | 1983-03-08 | 1987-11-24 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| US4567043A (en) * | 1983-06-15 | 1986-01-28 | American Home Products Corporation (Del.) | Canine corona virus vaccine |
| US5238662A (en) * | 1987-07-31 | 1993-08-24 | Chevron Research Company | Processes for recovering precious metals |
| US5147966A (en) * | 1990-07-31 | 1992-09-15 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Polyimide molding powder, coating, adhesive and matrix resin |
| FR2781159B1 (fr) * | 1998-07-06 | 2000-10-06 | Merial Sas | Vaccin circovirus et parvovirus porcin |
| US6391314B1 (en) * | 1997-10-03 | 2002-05-21 | Merial | Porcine circoviruses vaccines diagnostic reagents |
| UA78180C2 (uk) * | 1997-10-03 | 2007-03-15 | Меріаль | Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти |
| FR2769322B1 (fr) * | 1997-10-03 | 2002-03-08 | Merial Sas | Nouveaux circovirus porcins, vaccins et reactifs de diagnostic |
| US20040062775A1 (en) * | 1997-12-05 | 2004-04-01 | Agence Francaise De Securite Sanitaire Des Aliments | Circovirus sequences associated with piglet weight loss disease (PWD) |
| FR2772047B1 (fr) * | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
| WO1999045956A1 (en) * | 1998-03-13 | 1999-09-16 | University Of Georgia Research Foundation, Inc. | Vaccines against circovirus infections |
| CA2442135C (en) * | 2001-03-27 | 2008-08-19 | University Of Saskatchewan | Methods to culture circovirus |
| US20030096377A1 (en) * | 2001-06-28 | 2003-05-22 | Virginia Tech Intellectual Properties, Inc. | Differential PCR-RFLP assay for detecting and distinguishing between nonpathogenic PCV-1 and pathogenic PCV-2 |
| US7279166B2 (en) * | 2001-12-12 | 2007-10-09 | Virginia Tech Intellectual Properties, Inc. | Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof |
| US7276353B2 (en) * | 2001-12-12 | 2007-10-02 | Virginia Tech Intellectual Properties, Inc. | Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof |
| DK2371383T3 (en) * | 2005-12-29 | 2015-11-30 | Boehringer Ingelheim Vetmed | Use of a PCV2 immunogenic composition for reduction of clinical symptoms in pigs |
-
2008
- 2008-12-18 US US12/338,226 patent/US20090162398A1/en not_active Abandoned
- 2008-12-18 KR KR1020107016228A patent/KR20100094587A/ko not_active Ceased
- 2008-12-18 CL CL2008003813A patent/CL2008003813A1/es unknown
- 2008-12-18 NZ NZ586238A patent/NZ586238A/xx unknown
- 2008-12-18 UA UAA201007554A patent/UA99495C2/ru unknown
- 2008-12-18 CN CN2008801255848A patent/CN101932700A/zh active Pending
- 2008-12-18 BR BRPI0821286A patent/BRPI0821286A8/pt not_active Application Discontinuation
- 2008-12-18 CA CA2710247A patent/CA2710247C/en active Active
- 2008-12-18 WO PCT/US2008/087361 patent/WO2009085912A1/en not_active Ceased
- 2008-12-18 RU RU2010124791/10A patent/RU2493254C9/ru active
- 2008-12-18 ME MEP-2010-93A patent/ME01156B/me unknown
- 2008-12-18 AU AU2008343172A patent/AU2008343172B2/en not_active Withdrawn - After Issue
- 2008-12-18 JP JP2010539780A patent/JP2011507522A/ja active Pending
- 2008-12-18 EP EP08867869A patent/EP2225367A1/en not_active Ceased
- 2008-12-19 AR ARP080105635A patent/AR069882A1/es not_active Application Discontinuation
-
2010
- 2010-06-21 CO CO10074488A patent/CO6290791A2/es not_active Application Discontinuation
-
2011
- 2011-03-09 US US13/043,853 patent/US20110305725A1/en not_active Abandoned
-
2016
- 2016-09-29 JP JP2016191501A patent/JP2017060473A/ja active Pending
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