JP2016533753A5 - - Google Patents
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- Publication number
- JP2016533753A5 JP2016533753A5 JP2016537898A JP2016537898A JP2016533753A5 JP 2016533753 A5 JP2016533753 A5 JP 2016533753A5 JP 2016537898 A JP2016537898 A JP 2016537898A JP 2016537898 A JP2016537898 A JP 2016537898A JP 2016533753 A5 JP2016533753 A5 JP 2016533753A5
- Authority
- JP
- Japan
- Prior art keywords
- kynureninase
- present
- therapy
- seq
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361872132P | 2013-08-30 | 2013-08-30 | |
| US61/872,132 | 2013-08-30 | ||
| US201461986366P | 2014-04-30 | 2014-04-30 | |
| US61/986,366 | 2014-04-30 | ||
| PCT/US2014/053437 WO2015031771A2 (en) | 2013-08-30 | 2014-08-29 | Administration of kynurenine depleting enzymes for tumor therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018042760A Division JP7029316B2 (ja) | 2013-08-30 | 2018-03-09 | 腫瘍の治療のための、キヌレニンを枯渇させる酵素の投与 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016533753A JP2016533753A (ja) | 2016-11-04 |
| JP2016533753A5 true JP2016533753A5 (enExample) | 2017-10-05 |
| JP6307163B2 JP6307163B2 (ja) | 2018-04-04 |
Family
ID=52583559
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016537898A Active JP6307163B2 (ja) | 2013-08-30 | 2014-08-29 | 腫瘍の治療のための、キヌレニンを枯渇させる酵素の投与 |
| JP2018042760A Active JP7029316B2 (ja) | 2013-08-30 | 2018-03-09 | 腫瘍の治療のための、キヌレニンを枯渇させる酵素の投与 |
| JP2020073212A Withdrawn JP2020111611A (ja) | 2013-08-30 | 2020-04-16 | 腫瘍の治療のための、キヌレニンを枯渇させる酵素の投与 |
| JP2022132161A Pending JP2022159570A (ja) | 2013-08-30 | 2022-08-23 | 腫瘍の治療のための、キヌレニンを枯渇させる酵素の投与 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018042760A Active JP7029316B2 (ja) | 2013-08-30 | 2018-03-09 | 腫瘍の治療のための、キヌレニンを枯渇させる酵素の投与 |
| JP2020073212A Withdrawn JP2020111611A (ja) | 2013-08-30 | 2020-04-16 | 腫瘍の治療のための、キヌレニンを枯渇させる酵素の投与 |
| JP2022132161A Pending JP2022159570A (ja) | 2013-08-30 | 2022-08-23 | 腫瘍の治療のための、キヌレニンを枯渇させる酵素の投与 |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US9808486B2 (enExample) |
| EP (2) | EP3492094A1 (enExample) |
| JP (4) | JP6307163B2 (enExample) |
| KR (2) | KR102442231B1 (enExample) |
| CN (2) | CN113957061A (enExample) |
| AU (1) | AU2014312119B2 (enExample) |
| BR (1) | BR112016004095A2 (enExample) |
| CA (2) | CA2922670C (enExample) |
| ES (1) | ES2707711T3 (enExample) |
| IL (2) | IL244312B (enExample) |
| WO (1) | WO2015031771A2 (enExample) |
| ZA (1) | ZA201601443B (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4282419A1 (en) | 2012-12-20 | 2023-11-29 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| WO2015031771A2 (en) * | 2013-08-30 | 2015-03-05 | Board Of Regents, The University Of Texas System | Administration of kynurenine depleting enzymes for tumor therapy |
| EP3186371B1 (en) | 2014-08-29 | 2024-08-14 | Board of Regents, The University of Texas System | Administration of kynurenine depleting enzymes for tumor therapy |
| BR112017007765B1 (pt) | 2014-10-14 | 2023-10-03 | Halozyme, Inc | Composições de adenosina deaminase-2 (ada2), variantes do mesmo e métodos de usar o mesmo |
| EP3271463A4 (en) * | 2015-03-18 | 2018-08-01 | Baylor College of Medicine | Her2/erbb2 chimeric antigen receptor |
| CA3011283A1 (en) | 2016-01-11 | 2017-07-20 | Synlogic Operating Company, Inc. | Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells |
| US11542486B2 (en) | 2016-03-02 | 2023-01-03 | Board Of Regents, The University Of Texas System | Human kynureninase enzyme variants having improved pharmacological properties |
| US12144850B2 (en) | 2016-04-08 | 2024-11-19 | Purdue Research Foundation | Methods and compositions for car T cell therapy |
| ES2939646T3 (es) | 2016-10-13 | 2023-04-25 | Juno Therapeutics Inc | Métodos y composiciones de inmunoterapia que comprenden moduladores de la vía metabólica del triptófano |
| AU2018219226B2 (en) | 2017-02-07 | 2024-12-19 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
| ES3010559T3 (en) | 2017-02-28 | 2025-04-03 | Endocyte Inc | Compositions and methods for car t cell therapy |
| CN111246865A (zh) | 2017-07-12 | 2020-06-05 | 同生运营公司 | 程序化以在肿瘤细胞中产生免疫调节剂和抗癌治疗剂的微生物 |
| WO2019089740A1 (en) * | 2017-11-03 | 2019-05-09 | Dana-Farber Cancer Institute, Inc. | Biomarkers of clinical response and benefit to immune checkpoint inhibitor therapy |
| US11311576B2 (en) | 2018-01-22 | 2022-04-26 | Seattle Children's Hospital | Methods of use for CAR T cells |
| WO2019156795A1 (en) | 2018-02-06 | 2019-08-15 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors |
| CA3091674A1 (en) | 2018-02-23 | 2019-08-29 | Endocyte, Inc. | Sequencing method for car t cell therapy |
| BR112020020772A2 (pt) | 2018-04-16 | 2021-02-02 | Board Of Regents, The University Of Texas System | enzimas quinureninase humana e usos das mesmas |
| CN110412179A (zh) * | 2018-04-26 | 2019-11-05 | 缪荣明 | 一种液相色谱检测颗粒酶a的方法 |
| US20220056407A1 (en) * | 2018-12-14 | 2022-02-24 | Autolus Limited | Cell |
| US20210115416A1 (en) * | 2019-10-17 | 2021-04-22 | Ikena Oncology, Inc. | Pegylated kynureninase enzymes and uses thereof for the treatment of cancer |
| KR20220163940A (ko) | 2020-02-04 | 2022-12-12 | 시애틀 칠드런즈 호스피탈 디/비/에이 시애틀 칠드런즈 리서치 인스티튜트 | 항-디니트로페놀 키메라 항원 수용체 |
| JPWO2023229024A1 (enExample) * | 2022-05-27 | 2023-11-30 | ||
| WO2024085280A1 (ko) * | 2022-10-20 | 2024-04-25 | 서울대학교 산학협력단 | 신규한 키뉴레니나제 및 이의 용도 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824311A (en) | 1987-11-30 | 1998-10-20 | Trustees Of The University Of Pennsylvania | Treatment of tumors with monoclonal antibodies against oncogene antigens |
| US4870287A (en) | 1988-03-03 | 1989-09-26 | Loma Linda University Medical Center | Multi-station proton beam therapy system |
| US5329028A (en) | 1992-08-05 | 1994-07-12 | Genentech, Inc. | Carbohydrate-directed cross-linking reagents |
| US5801029A (en) | 1993-02-16 | 1998-09-01 | Onyx Pharmaceuticals, Inc. | Cytopathic viruses for therapy and prophylaxis of neoplasia |
| US5801005A (en) | 1993-03-17 | 1998-09-01 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated |
| GB9506466D0 (en) | 1994-08-26 | 1995-05-17 | Prolifix Ltd | Cell cycle regulated repressor and dna element |
| US5760395A (en) | 1996-04-18 | 1998-06-02 | Universities Research Assoc., Inc. | Method and apparatus for laser-controlled proton beam radiology |
| US5739169A (en) | 1996-05-31 | 1998-04-14 | Procept, Incorporated | Aromatic compounds for inhibiting immune response |
| US6812339B1 (en) * | 2000-09-08 | 2004-11-02 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| US20030194721A1 (en) | 2001-09-19 | 2003-10-16 | Incyte Genomics, Inc. | Genes expressed in treated foam cells |
| WO2003065984A2 (en) | 2002-02-01 | 2003-08-14 | Millennium Pharmaceuticals, Inc. | Methods and compositions for treating cardiovascular disease |
| CN1330774C (zh) * | 2002-03-01 | 2007-08-08 | 国家人类基因组南方研究中心 | 犬尿氨酸水解酶多态性及其用途 |
| CA2520172C (en) * | 2003-03-27 | 2012-10-02 | Lankenau Institute For Medical Research | Novel methods for the treatment of cancer with an indoleamine 2, 3-dioxygenase inhibitor |
| US20070207158A1 (en) | 2003-06-17 | 2007-09-06 | Harrison Roger G | Conjugate for the specific targeting of anticancer agents to tumor cells or tumor vasculature and production thereof |
| US7109304B2 (en) | 2003-07-31 | 2006-09-19 | Immunomedics, Inc. | Humanized anti-CD19 antibodies |
| JP2008237022A (ja) * | 2005-06-30 | 2008-10-09 | Osaka Prefecture | 非小細胞肺がんの予防・治療剤および診断薬 |
| JP5319532B2 (ja) * | 2006-09-19 | 2013-10-16 | インサイト・コーポレイション | インドールアミン２，３−ジオキシゲナーゼのモジュレーターとしてのｎ−ヒドロキシアミジノヘテロサイクル |
| GB0625310D0 (en) * | 2006-12-19 | 2007-01-24 | Bioalvo | Yeast platform construction and screening methods |
| US8465743B2 (en) | 2009-10-01 | 2013-06-18 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer |
| EP2614077B1 (en) | 2010-09-08 | 2016-08-17 | Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus | Chimeric antigen receptors with an optimized hinge region |
| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| KR20120085209A (ko) * | 2011-01-21 | 2012-07-31 | 인제대학교 산학협력단 | 트립토판 대사효소 유전자를 발현하는 줄기세포를 함유하는 면역 반응 억제용 조성물 |
| WO2012099441A2 (ko) * | 2011-01-21 | 2012-07-26 | 인제대학교산학협력단 | 트립토판 대사효소 유전자를 발현하는 줄기세포를 함유하는 면역 반응 억제용 조성물 |
| RU2640913C2 (ru) * | 2011-09-07 | 2018-01-12 | Дойчес Кребсфоршунгсцентрум | Средства и способы лечения и/или предотвращения рака, зависимого от природного лиганда ahr |
| IN2014CN02906A (enExample) | 2011-10-20 | 2015-07-03 | Us Health | |
| WO2015031771A2 (en) * | 2013-08-30 | 2015-03-05 | Board Of Regents, The University Of Texas System | Administration of kynurenine depleting enzymes for tumor therapy |
| EP3186371B1 (en) | 2014-08-29 | 2024-08-14 | Board of Regents, The University of Texas System | Administration of kynurenine depleting enzymes for tumor therapy |
| US11542486B2 (en) | 2016-03-02 | 2023-01-03 | Board Of Regents, The University Of Texas System | Human kynureninase enzyme variants having improved pharmacological properties |
| JP6912171B2 (ja) * | 2016-09-15 | 2021-07-28 | 株式会社トプコン | 眼科検査装置 |
| BR112020020772A2 (pt) | 2018-04-16 | 2021-02-02 | Board Of Regents, The University Of Texas System | enzimas quinureninase humana e usos das mesmas |
-
2014
- 2014-08-29 WO PCT/US2014/053437 patent/WO2015031771A2/en not_active Ceased
- 2014-08-29 CA CA2922670A patent/CA2922670C/en active Active
- 2014-08-29 BR BR112016004095A patent/BR112016004095A2/pt not_active Application Discontinuation
- 2014-08-29 ES ES14840339T patent/ES2707711T3/es active Active
- 2014-08-29 JP JP2016537898A patent/JP6307163B2/ja active Active
- 2014-08-29 KR KR1020217019661A patent/KR102442231B1/ko active Active
- 2014-08-29 CN CN202111132607.1A patent/CN113957061A/zh active Pending
- 2014-08-29 US US14/473,040 patent/US9808486B2/en active Active
- 2014-08-29 CN CN201480053899.1A patent/CN105722522B/zh active Active
- 2014-08-29 EP EP18204264.8A patent/EP3492094A1/en not_active Withdrawn
- 2014-08-29 KR KR1020167008486A patent/KR102271498B1/ko active Active
- 2014-08-29 CA CA3173052A patent/CA3173052A1/en active Pending
- 2014-08-29 AU AU2014312119A patent/AU2014312119B2/en active Active
- 2014-08-29 EP EP14840339.7A patent/EP3038636B1/en active Active
-
2016
- 2016-02-28 IL IL244312A patent/IL244312B/en active IP Right Grant
- 2016-03-02 ZA ZA2016/01443A patent/ZA201601443B/en unknown
- 2016-11-14 US US15/351,060 patent/US20170056449A1/en not_active Abandoned
-
2018
- 2018-03-09 JP JP2018042760A patent/JP7029316B2/ja active Active
-
2019
- 2019-02-19 IL IL264901A patent/IL264901B/en active IP Right Grant
- 2019-04-02 US US16/373,588 patent/US10772913B2/en active Active
-
2020
- 2020-04-16 JP JP2020073212A patent/JP2020111611A/ja not_active Withdrawn
- 2020-08-18 US US16/996,806 patent/US11534463B2/en active Active
-
2022
- 2022-08-23 JP JP2022132161A patent/JP2022159570A/ja active Pending
- 2022-12-13 US US18/065,451 patent/US20240091258A1/en active Pending
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