JP2018505893A5 - - Google Patents

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JP2018505893A5
JP2018505893A5 JP2017541808A JP2017541808A JP2018505893A5 JP 2018505893 A5 JP2018505893 A5 JP 2018505893A5 JP 2017541808 A JP2017541808 A JP 2017541808A JP 2017541808 A JP2017541808 A JP 2017541808A JP 2018505893 A5 JP2018505893 A5 JP 2018505893A5
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human igg
glycosylated
variant human
polypeptide
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JP2017541808A
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JP2018505893A (ja
JP6724023B2 (ja
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Priority claimed from PCT/US2016/017100 external-priority patent/WO2016130516A1/en
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JP2017541808A 2015-02-09 2016-02-09 改善された補体活性化を示す操作された免疫グロブリンｆｃポリペプチド Active JP6724023B2 (ja)

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JP2020108886A JP6926285B2 (ja) 2015-02-09 2020-06-24 改善された補体活性化を示す操作された免疫グロブリンｆｃポリペプチド

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US201562113717P 2015-02-09 2015-02-09
US62/113,717 2015-02-09
PCT/US2016/017100 WO2016130516A1 (en) 2015-02-09 2016-02-09 Engineered immunoglobulin fc polypeptides displaying improved complement activation

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JP2018505893A JP2018505893A (ja) 2018-03-01
JP2018505893A5 true JP2018505893A5 (enExample) 2018-12-27
JP6724023B2 JP6724023B2 (ja) 2020-07-15

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JP2020108886A Active JP6926285B2 (ja) 2015-02-09 2020-06-24 改善された補体活性化を示す操作された免疫グロブリンｆｃポリペプチド

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US (2) US10457737B2 (enExample)
EP (1) EP3256490A1 (enExample)
JP (2) JP6724023B2 (enExample)
AU (1) AU2016219511B2 (enExample)
CA (1) CA2976236A1 (enExample)
WO (1) WO2016130516A1 (enExample)

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SG10201607778XA (en) 2016-09-16 2018-04-27 Chugai Pharmaceutical Co Ltd Anti-Dengue Virus Antibodies, Polypeptides Containing Variant Fc Regions, And Methods Of Use
EP3535291A1 (en) * 2016-11-01 2019-09-11 Genmab B.V. Polypeptide variants and uses thereof
TW201834688A (zh) 2017-02-24 2018-10-01 日商中外製藥股份有限公司 藥學組成物、抗原結合分子、治療方法以及篩選方法
KR20200132938A (ko) 2018-03-15 2020-11-25 추가이 세이야쿠 가부시키가이샤 지카 바이러스에 대해 교차-반응성을 갖는 항-뎅기 바이러스 항체 및 사용 방법
JP7523349B2 (ja) * 2018-08-29 2024-07-26 中外製薬株式会社 抗体半分子、および抗体半分子のホモ二量体形成を抑制する方法
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GB2595299B (en) 2020-05-21 2022-08-03 Mabsolve Ltd Modified immunoglobulin FC regions
JP2024500354A (ja) * 2020-12-10 2024-01-09 インベンラ， インコーポレイテッド ヘテロ二量体化のための直交変異
US20240425612A1 (en) * 2021-10-18 2024-12-26 Korea University Research And Business Foundation Fc variants having improved ph-dependent fcrn binding capacity and fcriiia binding selectivity
JP2024544531A (ja) * 2021-11-11 2024-12-03 マクファーレン バーネット インスティテュート フォー メディカル リサーチ アンド パブリック ヘルス リミテッド 位置４２９に変異を有するｆｃ領域成分を含む免疫療法タンパク質
WO2023081958A1 (en) * 2021-11-11 2023-05-19 The Macfarlane Burnet Institute For Medical Research And Public Health Ltd Antiviral agent comprising a cellular entry receptor and fc region component
WO2024229532A1 (en) * 2023-05-10 2024-11-14 Macfarlane Burnet Institute For Medical Research And Public Health Limited Immunotherapeutic proteins
AU2024269644A1 (en) * 2023-05-10 2025-11-27 Macfarlane Burnet Institute For Medical Research And Public Health Limited Immunotherapeutic proteins

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