JP2016528179A5 - - Google Patents
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- JP2016528179A5 JP2016528179A5 JP2016519576A JP2016519576A JP2016528179A5 JP 2016528179 A5 JP2016528179 A5 JP 2016528179A5 JP 2016519576 A JP2016519576 A JP 2016519576A JP 2016519576 A JP2016519576 A JP 2016519576A JP 2016528179 A5 JP2016528179 A5 JP 2016528179A5
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- Prior art keywords
- crystal
- diffraction pattern
- ray diffraction
- compound
- formula
- Prior art date
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- 0 CC(C)C(CS(C(C)*)(=O)=O)N([C@@]([C@](C[C@]1(C)C*)c2cc(*)ccc2)c(cc2)ccc2Cl)C1=O Chemical compound CC(C)C(CS(C(C)*)(=O)=O)N([C@@]([C@](C[C@]1(C)C*)c2cc(*)ccc2)c(cc2)ccc2Cl)C1=O 0.000 description 2
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020084989A JP6891322B2 (ja) | 2013-06-10 | 2020-05-14 | 製造方法及びｍｄｍ２阻害剤の結晶形 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361833196P | 2013-06-10 | 2013-06-10 | |
| US61/833,196 | 2013-06-10 | ||
| PCT/US2014/041594 WO2014200937A1 (en) | 2013-06-10 | 2014-06-09 | Processes of making and crystalline forms of a mdm2 inhibitor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020084989A Division JP6891322B2 (ja) | 2013-06-10 | 2020-05-14 | 製造方法及びｍｄｍ２阻害剤の結晶形 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016528179A JP2016528179A (ja) | 2016-09-15 |
| JP2016528179A5 true JP2016528179A5 (https=) | 2017-07-20 |
| JP6998655B2 JP6998655B2 (ja) | 2022-02-04 |
Family
ID=51063849
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016519576A Active JP6998655B2 (ja) | 2013-06-10 | 2014-06-09 | 製造方法及びｍｄｍ２阻害剤の結晶形 |
| JP2020084989A Active JP6891322B2 (ja) | 2013-06-10 | 2020-05-14 | 製造方法及びｍｄｍ２阻害剤の結晶形 |
| JP2021087378A Active JP7263439B2 (ja) | 2013-06-10 | 2021-05-25 | 製造方法及びｍｄｍ２阻害剤の結晶形 |
| JP2023064715A Pending JP2023089126A (ja) | 2013-06-10 | 2023-04-12 | 製造方法及びｍｄｍ２阻害剤の結晶形 |
| JP2025029906A Pending JP2025084856A (ja) | 2013-06-10 | 2025-02-27 | 製造方法及びｍｄｍ２阻害剤の結晶形 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020084989A Active JP6891322B2 (ja) | 2013-06-10 | 2020-05-14 | 製造方法及びｍｄｍ２阻害剤の結晶形 |
| JP2021087378A Active JP7263439B2 (ja) | 2013-06-10 | 2021-05-25 | 製造方法及びｍｄｍ２阻害剤の結晶形 |
| JP2023064715A Pending JP2023089126A (ja) | 2013-06-10 | 2023-04-12 | 製造方法及びｍｄｍ２阻害剤の結晶形 |
| JP2025029906A Pending JP2025084856A (ja) | 2013-06-10 | 2025-02-27 | 製造方法及びｍｄｍ２阻害剤の結晶形 |
Country Status (38)
Families Citing this family (21)
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| JO2998B1 (ar) | 2010-06-04 | 2016-09-05 | Amgen Inc | مشتقات بيبيريدينون كمثبطات mdm2 لعلاج السرطان |
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| BR112016010564A2 (pt) | 2013-11-11 | 2017-10-10 | Amgen Inc | terapia de combinação incluindo um inibidor de mdm2 e um ou mais agentes farmaceuticamente ativos para tratamento de cânceres |
| CN118436801A (zh) | 2016-05-20 | 2024-08-06 | 豪夫迈·罗氏有限公司 | Protac抗体缀合物及其使用方法 |
| IL319432A (en) * | 2018-04-30 | 2025-05-01 | Kartos Therapeutics Inc | Methods of treating cancer |
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| AU2019327555B2 (en) | 2018-08-31 | 2025-01-16 | Amgen, Inc. | Processes for preparing a MDM2 inhibitor |
| CN110963958B (zh) * | 2018-09-30 | 2025-10-10 | 上海长森药业有限公司 | 一种mdm2抑制剂，及其制备方法、药物组合物和应用 |
| GB201919219D0 (en) | 2019-12-23 | 2020-02-05 | Otsuka Pharma Co Ltd | Cancer biomarkers |
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| GB202103080D0 (en) | 2021-03-04 | 2021-04-21 | Otsuka Pharma Co Ltd | Cancer biomarkers |
| WO2023014160A1 (ko) * | 2021-08-05 | 2023-02-09 | (주)바이오팜솔루션즈 | 페닐카바메이트 결정형 및 이의 제조 방법 |
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| US20250134877A1 (en) * | 2021-09-09 | 2025-05-01 | Kartos Therapeutics | Methods of treating cancer dependent on myc gene expresssion |
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| CN115925589A (zh) * | 2022-12-26 | 2023-04-07 | 诚达药业股份有限公司 | 一种脂肪族亚磺酸钙盐及其制备方法 |
| WO2024240858A1 (en) | 2023-05-23 | 2024-11-28 | Valerio Therapeutics | Protac molecules directed against dna damage repair system and uses thereof |
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2014
- 2014-06-09 CN CN201480033215.1A patent/CN105358530A/zh active Pending
- 2014-06-09 MY MYPI2015002896A patent/MY194848A/en unknown
- 2014-06-09 DK DK14735785.9T patent/DK3008039T3/da active
- 2014-06-09 NZ NZ714821A patent/NZ714821A/en unknown
- 2014-06-09 WO PCT/US2014/041594 patent/WO2014200937A1/en not_active Ceased
- 2014-06-09 BR BR112015031004-4A patent/BR112015031004B1/pt active IP Right Grant
- 2014-06-09 KR KR1020217030265A patent/KR20210121270A/ko not_active Ceased
- 2014-06-09 MX MX2019012007A patent/MX379872B/es unknown
- 2014-06-09 KR KR1020157036194A patent/KR20160018576A/ko not_active Ceased
- 2014-06-09 SI SI201431735T patent/SI3008039T1/sl unknown
- 2014-06-09 PL PL14735785T patent/PL3008039T3/pl unknown
- 2014-06-09 PH PH1/2020/550916A patent/PH12020550916A1/en unknown
- 2014-06-09 CA CA3115609A patent/CA3115609C/en active Active
- 2014-06-09 HU HUE14735785A patent/HUE053047T2/hu unknown
- 2014-06-09 CN CN201910783352.1A patent/CN110627708A/zh active Pending
- 2014-06-09 IL IL297860A patent/IL297860A/en unknown
- 2014-06-09 CA CA3200532A patent/CA3200532A1/en active Pending
- 2014-06-09 HR HRP20202065TT patent/HRP20202065T1/hr unknown
- 2014-06-09 BR BR122020003153-0A patent/BR122020003153B1/pt active IP Right Grant
- 2014-06-09 CN CN201811222652.4A patent/CN110003092A/zh active Pending
- 2014-06-09 UA UAA202000229A patent/UA129695C2/uk unknown
- 2014-06-09 MA MA53572A patent/MA53572A1/fr unknown
- 2014-06-09 CA CA2914723A patent/CA2914723C/en active Active
- 2014-06-09 UA UAA201600159A patent/UA121301C2/uk unknown
- 2014-06-09 AU AU2014278428A patent/AU2014278428B2/en active Active
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