JP2016518403A5 - - Google Patents
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- Publication number
- JP2016518403A5 JP2016518403A5 JP2016512480A JP2016512480A JP2016518403A5 JP 2016518403 A5 JP2016518403 A5 JP 2016518403A5 JP 2016512480 A JP2016512480 A JP 2016512480A JP 2016512480 A JP2016512480 A JP 2016512480A JP 2016518403 A5 JP2016518403 A5 JP 2016518403A5
- Authority
- JP
- Japan
- Prior art keywords
- trehalose
- pharmaceutical
- pharmaceutical formulation
- effective amount
- therapeutically effective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361820278P | 2013-05-07 | 2013-05-07 | |
| US61/820,278 | 2013-05-07 | ||
| PCT/IL2014/050411 WO2014181333A2 (en) | 2013-05-07 | 2014-05-07 | Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019075517A Division JP2019142907A (ja) | 2013-05-07 | 2019-04-11 | トレハロースの非経口投与によるタンパク質凝集ミオパシーおよび神経変性疾患の治療 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016518403A JP2016518403A (ja) | 2016-06-23 |
| JP2016518403A5 true JP2016518403A5 (enExample) | 2017-06-15 |
| JP6837835B2 JP6837835B2 (ja) | 2021-03-03 |
Family
ID=51022384
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016512480A Active JP6837835B2 (ja) | 2013-05-07 | 2014-05-07 | トレハロースの非経口投与によるタンパク質凝集ミオパシーおよび神経変性疾患の治療 |
| JP2019075517A Pending JP2019142907A (ja) | 2013-05-07 | 2019-04-11 | トレハロースの非経口投与によるタンパク質凝集ミオパシーおよび神経変性疾患の治療 |
| JP2021095562A Pending JP2021152032A (ja) | 2013-05-07 | 2021-06-08 | トレハロースの非経口投与によるタンパク質凝集ミオパシーおよび神経変性疾患の治療 |
| JP2023002536A Pending JP2023040211A (ja) | 2013-05-07 | 2023-01-11 | トレハロースの非経口投与によるタンパク質凝集ミオパシーおよび神経変性疾患の治療 |
| JP2025036306A Pending JP2025087858A (ja) | 2013-05-07 | 2025-03-07 | トレハロースの非経口投与によるタンパク質凝集ミオパシーおよび神経変性疾患の治療 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019075517A Pending JP2019142907A (ja) | 2013-05-07 | 2019-04-11 | トレハロースの非経口投与によるタンパク質凝集ミオパシーおよび神経変性疾患の治療 |
| JP2021095562A Pending JP2021152032A (ja) | 2013-05-07 | 2021-06-08 | トレハロースの非経口投与によるタンパク質凝集ミオパシーおよび神経変性疾患の治療 |
| JP2023002536A Pending JP2023040211A (ja) | 2013-05-07 | 2023-01-11 | トレハロースの非経口投与によるタンパク質凝集ミオパシーおよび神経変性疾患の治療 |
| JP2025036306A Pending JP2025087858A (ja) | 2013-05-07 | 2025-03-07 | トレハロースの非経口投与によるタンパク質凝集ミオパシーおよび神経変性疾患の治療 |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US10493023B2 (enExample) |
| EP (2) | EP4218769A3 (enExample) |
| JP (5) | JP6837835B2 (enExample) |
| KR (1) | KR20160009617A (enExample) |
| AU (5) | AU2014264228A1 (enExample) |
| CA (2) | CA3239805A1 (enExample) |
| CR (1) | CR20150637A (enExample) |
| EA (1) | EA201501054A1 (enExample) |
| IL (1) | IL241757B (enExample) |
| MD (1) | MD20150120A2 (enExample) |
| MX (1) | MX2015015355A (enExample) |
| PE (1) | PE20160012A1 (enExample) |
| SG (1) | SG11201509030TA (enExample) |
| WO (1) | WO2014181333A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9084720B2 (en) * | 2013-05-07 | 2015-07-21 | BioBlast Pharma Ltd. | Compositions and methods for treating oculopharyngeal muscular dystrophy |
| US20220288096A1 (en) * | 2013-05-07 | 2022-09-15 | Seelos Therapeutics, Inc. | Compositions and methods for treating an aggregation disease or disorder |
| CA3239805A1 (en) | 2013-05-07 | 2014-11-13 | Seelos Therapeutics, Inc. | Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose |
| US10736909B2 (en) * | 2016-02-08 | 2020-08-11 | Junaxo, Inc. | Use of trehalose for treatment of neurological diseases |
| NZ748599A (en) | 2016-04-21 | 2022-08-26 | Baylor College Medicine | Compositions and methods for the treatment of lysosomal storage disorders and disorders characterized by lysosomal dysfunction |
| LT4154882T (lt) | 2017-08-14 | 2025-11-25 | Amiotrofinės lateralinės sklerozės gydymas pridopidinu | |
| WO2019143685A1 (en) | 2018-01-16 | 2019-07-25 | Women & Infants Hospital Of Rhode Island | Methods and compositions for treating pre-eclampsia |
| BR112022006012A2 (pt) * | 2019-10-01 | 2022-07-12 | Seelos Therapeutics Inc | Formulações de trealose e usos das mesmas |
| AU2021219072B2 (en) * | 2020-02-13 | 2024-10-03 | Prilenia Neurotherapeutics Ltd. | Combination therapy for treating amyotrophic lateral using pridopidine and another active agent |
| WO2022013940A1 (ja) | 2020-07-14 | 2022-01-20 | オリンパス株式会社 | 嚥下検査用システム、嚥下検査方法及び嚥下検査プログラムを記録した記録媒体 |
| CN116966192A (zh) * | 2022-09-26 | 2023-10-31 | 西安文理学院 | 海藻糖在制备sca3疾病治疗药物中的应用 |
| AU2023403437A1 (en) * | 2022-11-30 | 2025-06-19 | GLD Debt Acquisition 2025-1, Inc. | Trehalose for treating huntington's disease |
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| US3782404A (en) | 1972-06-14 | 1974-01-01 | Commercial Shearing | Adjustable, metered, directional flow control arrangements |
| JPS4950521U (enExample) | 1972-08-14 | 1974-05-02 | ||
| JPS516109B2 (enExample) | 1972-12-28 | 1976-02-25 | ||
| JPS557829Y2 (enExample) | 1974-07-01 | 1980-02-21 | ||
| JPS516109A (en) | 1974-07-05 | 1976-01-19 | Toshiba Tungaloy Co Ltd | Aruminaatankachitan chitsukachitankeishoketsugokin |
| AU1172097A (en) | 1995-12-27 | 1997-07-28 | Rohto Pharmaceutical Co., Ltd. | Pharmaceutical composition containing trehalose |
| JP4033510B2 (ja) | 1995-12-27 | 2008-01-16 | ロート製薬株式会社 | トレハロースを含有する眼科用医薬組成物 |
| JP3455633B2 (ja) | 1996-06-28 | 2003-10-14 | 味の素ファルマ株式会社 | 潰瘍性大腸炎の予防又は治療剤 |
| US6440446B1 (en) | 1998-04-22 | 2002-08-27 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Agent for anti-osteoporosis |
| US6602865B1 (en) | 1998-11-16 | 2003-08-05 | Ivax Drug Research Institute, Ltd. | Pyridazino(4,5-b)(1,5)oxazepinone, -thiazepinone and -diazepinone compounds |
| JP2001302517A (ja) * | 2000-04-24 | 2001-10-31 | Tokyo Univ Of Pharmacy & Life Science | 脳浮腫の予防治療薬 |
| CA2355814C (en) | 2000-09-14 | 2010-06-29 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Pharmaceutical composition for ophthalmic use |
| JP4754066B2 (ja) | 2000-12-22 | 2011-08-24 | 株式会社林原生物化学研究所 | 抗関節障害剤 |
| JP4255101B2 (ja) | 2002-03-15 | 2009-04-15 | 独立行政法人理化学研究所 | 神経変性疾患の治療薬 |
| WO2004060343A1 (en) * | 2002-12-31 | 2004-07-22 | Nektar Therapeutics | Antibody-containing particles and compositions |
| EP3143983A1 (en) | 2003-02-13 | 2017-03-22 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | External dermatological formulation comprising saccharide derivative of alpha, alpha-trehalose |
| US20050215562A1 (en) * | 2003-06-23 | 2005-09-29 | Patrick Tremblay | Methods for treating protein aggregation disorders |
| US20050100637A1 (en) | 2003-11-12 | 2005-05-12 | Robert Murray | Carbohydrate and electrolyte replacement composition |
| US20060099567A1 (en) * | 2004-04-08 | 2006-05-11 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
| US20060257391A1 (en) * | 2005-05-11 | 2006-11-16 | Bausch & Lomb Incorporated | Non-surgical method for preventing or reducing the rate of the progression of non-proliferative diabetic retinopathy and the treatment of other ocular conditions |
| WO2006124892A2 (en) | 2005-05-13 | 2006-11-23 | Whitehead Institute For Biomedical Research | Modulators of alpha-synuclein toxicity |
| MY142987A (en) | 2005-06-08 | 2011-02-14 | Hayashibara Biochem Lab | Solution for tissue adhesion prevention and method for tissue adhesion prevention |
| JP2006342108A (ja) * | 2005-06-09 | 2006-12-21 | Mitsubishi Chemicals Corp | アミロスフェロイドにより発生する疾患の予防治療剤 |
| WO2007018124A1 (ja) | 2005-08-11 | 2007-02-15 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | コラーゲン産生増強剤とその用途 |
| KR101413770B1 (ko) | 2005-11-30 | 2014-06-30 | 닛신 오일리오그룹 가부시키가이샤 | 트레할로오스 지방산 에스테르 조성물 |
| JP4950521B2 (ja) | 2006-03-08 | 2012-06-13 | 公益財団法人野口研究所 | トレハロース誘導体とその製造法 |
| EP2000473B1 (en) | 2006-03-27 | 2011-04-06 | Otsuka Chemical Co., Ltd. | Trehalose compound and pharmaceutical comprising the compound |
| CN100571707C (zh) | 2006-07-24 | 2009-12-23 | 凌沛学 | 含有海藻糖的关节腔内注射给药制剂 |
| US20100093993A1 (en) | 2007-01-31 | 2010-04-15 | Otsuka Chemical Co., Ltd. | Trehalose compound, process for production of the compound, and immuno-stimulative agent comprising the compound |
| CN101646442B (zh) * | 2007-02-23 | 2013-09-04 | 21世纪国际新技术株式会社 | 血管痉挛的治疗剂或预防剂 |
| TW200848063A (en) | 2007-04-23 | 2008-12-16 | Combinatorx Inc | Methods and compositions for the treatment of neurodegenerative disorders |
| WO2009058399A1 (en) * | 2007-10-31 | 2009-05-07 | Diffusion Pharmaceuticals Llc | A new class of therapeutics that enhance small molecule diffusion |
| JP2009249292A (ja) * | 2008-04-01 | 2009-10-29 | Toray Ind Inc | ポリリン酸を安定化剤とするエリスロポエチン溶液製剤 |
| US20110142799A1 (en) * | 2008-06-23 | 2011-06-16 | President And Fellows Of Harvard College | Modulation of neurodegenerative disease by modulating xbp-1 activity |
| KR101021078B1 (ko) * | 2008-07-22 | 2011-03-14 | 포항공과대학교 산학협력단 | 이노시톨 또는 트리할로스 유도체 및 이를 함유하는 퇴행성뇌신경계 질환 치료용 약학 조성물 |
| EP2351764A4 (en) | 2008-10-31 | 2012-09-05 | Otsuka Chemical Co Ltd | TREHALOSE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND |
| CN102438652B (zh) * | 2008-11-12 | 2014-08-13 | 米迪缪尼有限公司 | 抗体制剂 |
| MX367131B (es) | 2008-12-10 | 2019-08-06 | Wista Lab Ltd | Sales de xantilio 3,6-disustituidas. |
| EP2248518B1 (en) | 2009-04-17 | 2013-01-16 | Merz Pharma GmbH & Co. KGaA | Formulation for stabilizing proteins, peptides or mixtures thereof. |
| US20120121580A1 (en) * | 2009-07-28 | 2012-05-17 | Merck Sharp & Dohme Corp. | Methods for producing high concentration lyophilized pharmaceutical formulations |
| JP5869882B2 (ja) * | 2010-03-05 | 2016-02-24 | 株式会社林原 | インスリン抵抗性の予防及び/又は改善剤 |
| UA115649C2 (uk) | 2010-06-25 | 2017-12-11 | Шае Хюмен Дженетік Терапіс, Інк. | Способи та композиції для доставки до цнс ідуронат-2-сульфатази |
| CN101914118B (zh) | 2010-08-06 | 2012-07-04 | 山东大学 | 海藻糖衍生物及其制备方法与应用 |
| WO2012061907A2 (en) * | 2010-11-10 | 2012-05-18 | Katholieke Universiteit Leuven | Osteoclast activity |
| US9186356B2 (en) | 2011-01-08 | 2015-11-17 | Academia Sinica | Methods for treating frontotemporal lobar degeneration with ubiquitinated inclusions (FTLD-U) |
| CN103764824B (zh) | 2011-06-20 | 2018-04-24 | 西奈山医学院 | 粘多糖贮积症和其它溶酶体病症的抗TNF-α疗法 |
| US8623839B2 (en) * | 2011-06-30 | 2014-01-07 | Depuy Mitek, Llc | Compositions and methods for stabilized polysaccharide formulations |
| US20130310467A1 (en) | 2012-03-06 | 2013-11-21 | The Nisshin Oillio Group, Ltd. | Trehalose fatty acid ester composition |
| JP5432322B2 (ja) | 2012-05-08 | 2014-03-05 | 株式会社大塚製薬工場 | トレハロース含有肺塞栓形成予防用哺乳動物細胞懸濁液 |
| US20130312784A1 (en) | 2012-05-24 | 2013-11-28 | For Your Ease Only, Inc. | Cosmetic organizer |
| US20140032304A1 (en) | 2012-07-27 | 2014-01-30 | Google Inc. | Determining a correlation between presentation of a content item and a transaction by a user at a point of sale terminal |
| JP2014139160A (ja) | 2012-12-21 | 2014-07-31 | Masaaki Hayashibara | 脳機能改善剤及び脳機能改善用食品 |
| CA3239805A1 (en) | 2013-05-07 | 2014-11-13 | Seelos Therapeutics, Inc. | Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose |
| US20220288096A1 (en) | 2013-05-07 | 2022-09-15 | Seelos Therapeutics, Inc. | Compositions and methods for treating an aggregation disease or disorder |
| US9084720B2 (en) | 2013-05-07 | 2015-07-21 | BioBlast Pharma Ltd. | Compositions and methods for treating oculopharyngeal muscular dystrophy |
| JP6130224B2 (ja) | 2013-05-27 | 2017-05-17 | 公益財団法人微生物化学研究会 | 新規化合物レンツトレハロース、その製造方法、及びその用途、並びに、新規微生物 |
| TWI507197B (zh) | 2013-07-17 | 2015-11-11 | Univ Nat Taiwan Normal | 醫藥組成物於製備不正常多麩醯胺聚集類疾病之藥物上之用途 |
| US10906981B2 (en) | 2013-07-19 | 2021-02-02 | The Regents Of The University Of California | Compositions and methods related to structures that cross the blood brain barrier |
| US20170354666A1 (en) | 2014-11-19 | 2017-12-14 | Rush University Medical Center | Compositions and methods for treating lysosomal disorders |
| US20160303150A1 (en) | 2015-04-16 | 2016-10-20 | BioBlast Pharma Ltd. | Deuterated trehalose formulations and uses thereof |
| WO2017136533A1 (en) | 2016-02-03 | 2017-08-10 | The Trustees Of The University Of Pennsylvania | Methods for treating diagnosing, and monitoring treatment of mucopolysaccharidoses |
| NZ748599A (en) | 2016-04-21 | 2022-08-26 | Baylor College Medicine | Compositions and methods for the treatment of lysosomal storage disorders and disorders characterized by lysosomal dysfunction |
| BR112022006012A2 (pt) | 2019-10-01 | 2022-07-12 | Seelos Therapeutics Inc | Formulações de trealose e usos das mesmas |
-
2014
- 2014-05-07 CA CA3239805A patent/CA3239805A1/en active Pending
- 2014-05-07 PE PE2015002367A patent/PE20160012A1/es not_active Application Discontinuation
- 2014-05-07 EA EA201501054A patent/EA201501054A1/ru unknown
- 2014-05-07 WO PCT/IL2014/050411 patent/WO2014181333A2/en not_active Ceased
- 2014-05-07 KR KR1020157034700A patent/KR20160009617A/ko not_active Withdrawn
- 2014-05-07 EP EP22216238.0A patent/EP4218769A3/en active Pending
- 2014-05-07 MX MX2015015355A patent/MX2015015355A/es unknown
- 2014-05-07 MD MDA20150120A patent/MD20150120A2/ro not_active Application Discontinuation
- 2014-05-07 EP EP14733380.1A patent/EP2994145B1/en active Active
- 2014-05-07 SG SG11201509030TA patent/SG11201509030TA/en unknown
- 2014-05-07 CA CA2911399A patent/CA2911399C/en active Active
- 2014-05-07 JP JP2016512480A patent/JP6837835B2/ja active Active
- 2014-05-07 US US14/889,727 patent/US10493023B2/en active Active
- 2014-05-07 AU AU2014264228A patent/AU2014264228A1/en not_active Abandoned
-
2015
- 2015-09-21 IL IL241757A patent/IL241757B/en active IP Right Grant
- 2015-12-04 CR CR20150637A patent/CR20150637A/es unknown
-
2019
- 2019-04-11 JP JP2019075517A patent/JP2019142907A/ja active Pending
- 2019-06-26 AU AU2019204513A patent/AU2019204513B2/en active Active
- 2019-07-02 US US16/460,046 patent/US10869831B2/en active Active
-
2020
- 2020-11-26 AU AU2020277197A patent/AU2020277197A1/en not_active Abandoned
-
2021
- 2021-06-08 JP JP2021095562A patent/JP2021152032A/ja active Pending
- 2021-06-23 US US17/355,607 patent/US20220117883A1/en not_active Abandoned
-
2023
- 2023-01-11 JP JP2023002536A patent/JP2023040211A/ja active Pending
- 2023-01-20 AU AU2023200303A patent/AU2023200303A1/en not_active Abandoned
- 2023-04-05 US US18/131,161 patent/US12239733B2/en active Active
-
2025
- 2025-03-07 JP JP2025036306A patent/JP2025087858A/ja active Pending
- 2025-03-13 AU AU2025201824A patent/AU2025201824A1/en active Pending
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