SG11201509030TA - Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose - Google Patents
Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehaloseInfo
- Publication number
- SG11201509030TA SG11201509030TA SG11201509030TA SG11201509030TA SG11201509030TA SG 11201509030T A SG11201509030T A SG 11201509030TA SG 11201509030T A SG11201509030T A SG 11201509030TA SG 11201509030T A SG11201509030T A SG 11201509030TA SG 11201509030T A SG11201509030T A SG 11201509030TA
- Authority
- SG
- Singapore
- Prior art keywords
- myopathic
- trehalose
- treatment
- parenteral administration
- neurodegenerative diseases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361820278P | 2013-05-07 | 2013-05-07 | |
| PCT/IL2014/050411 WO2014181333A2 (en) | 2013-05-07 | 2014-05-07 | Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201509030TA true SG11201509030TA (en) | 2015-11-27 |
Family
ID=51022384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201509030TA SG11201509030TA (en) | 2013-05-07 | 2014-05-07 | Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US10493023B2 (en) |
| EP (2) | EP2994145B1 (en) |
| JP (4) | JP6837835B2 (en) |
| KR (1) | KR20160009617A (en) |
| AU (4) | AU2014264228A1 (en) |
| CA (1) | CA2911399A1 (en) |
| CR (1) | CR20150637A (en) |
| EA (1) | EA201501054A1 (en) |
| HK (1) | HK1217300A1 (en) |
| IL (1) | IL241757B (en) |
| MD (1) | MD20150120A2 (en) |
| MX (1) | MX2015015355A (en) |
| PE (1) | PE20160012A1 (en) |
| SG (1) | SG11201509030TA (en) |
| WO (1) | WO2014181333A2 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9084720B2 (en) * | 2013-05-07 | 2015-07-21 | BioBlast Pharma Ltd. | Compositions and methods for treating oculopharyngeal muscular dystrophy |
| US20220288096A1 (en) * | 2013-05-07 | 2022-09-15 | Seelos Therapeutics, Inc. | Compositions and methods for treating an aggregation disease or disorder |
| KR20160009617A (en) | 2013-05-07 | 2016-01-26 | 바이오 블라스트 파마 리미티드 | Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose |
| US10736909B2 (en) | 2016-02-08 | 2020-08-11 | Junaxo, Inc. | Use of trehalose for treatment of neurological diseases |
| WO2017185010A1 (en) | 2016-04-21 | 2017-10-26 | Beyond Batten Disease Foundation | Compositions and methods for the treatment of lysosomal storage disorders and disorders characterized by lysosomal dysfunction |
| CN116370473A (en) | 2017-08-14 | 2023-07-04 | 普瑞尼亚神经治疗有限公司 | Method of treating amyotrophic lateral sclerosis with pridopidine |
| WO2019143685A1 (en) | 2018-01-16 | 2019-07-25 | Women & Infants Hospital Of Rhode Island | Methods and compositions for treating pre-eclampsia |
| CA3167214A1 (en) * | 2020-02-13 | 2021-08-19 | Michal Geva | Combination therapy for treating amyotrophic lateral using pridopidine and another active agent |
| WO2022013940A1 (en) * | 2020-07-14 | 2022-01-20 | オリンパス株式会社 | System for examination of swallowing, swallowing examination method, and recording medium in which swallowing examination program is recorded |
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| JPS516109B2 (en) | 1972-12-28 | 1976-02-25 | ||
| JPS516109A (en) | 1974-07-05 | 1976-01-19 | Toshiba Tungaloy Co Ltd | Aruminaatankachitan chitsukachitankeishoketsugokin |
| AU1172097A (en) | 1995-12-27 | 1997-07-28 | Rohto Pharmaceutical Co., Ltd. | Pharmaceutical composition containing trehalose |
| JP4033510B2 (en) | 1995-12-27 | 2008-01-16 | ロート製薬株式会社 | Ophthalmic pharmaceutical composition containing trehalose |
| JP3455633B2 (en) | 1996-06-28 | 2003-10-14 | 味の素ファルマ株式会社 | Agent for preventing or treating ulcerative colitis |
| US6440446B1 (en) | 1998-04-22 | 2002-08-27 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Agent for anti-osteoporosis |
| US6602865B1 (en) | 1998-11-16 | 2003-08-05 | Ivax Drug Research Institute, Ltd. | Pyridazino(4,5-b)(1,5)oxazepinone, -thiazepinone and -diazepinone compounds |
| JP2001302517A (en) * | 2000-04-24 | 2001-10-31 | Tokyo Univ Of Pharmacy & Life Science | Prophylactic and remedy for brain edema |
| AU781975B2 (en) | 2000-09-14 | 2005-06-23 | Hayashibara Co., Ltd | Pharmaceutical composition for ophthalmic use |
| JP4754066B2 (en) | 2000-12-22 | 2011-08-24 | 株式会社林原生物化学研究所 | Anti-joint disorder |
| JP4255101B2 (en) * | 2002-03-15 | 2009-04-15 | 独立行政法人理化学研究所 | Drugs for neurodegenerative diseases |
| EP1578394A4 (en) * | 2002-12-31 | 2011-02-23 | Nektar Therapeutics | Antibody-containing particles and compositions |
| CN1761450B (en) | 2003-02-13 | 2010-05-05 | 株式会社林原生物化学研究所 | Skin preparation for external use characterized by containing sugar derivative of a,a-trehalose |
| US20050215562A1 (en) * | 2003-06-23 | 2005-09-29 | Patrick Tremblay | Methods for treating protein aggregation disorders |
| US20050100637A1 (en) * | 2003-11-12 | 2005-05-12 | Robert Murray | Carbohydrate and electrolyte replacement composition |
| US20060099567A1 (en) * | 2004-04-08 | 2006-05-11 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
| AU2006247351A1 (en) | 2005-05-13 | 2006-11-23 | Whitehead Institute For Biomedical Research | Modulators of alpha-synuclein toxicity |
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| JP4950521B2 (en) | 2006-03-08 | 2012-06-13 | 公益財団法人野口研究所 | Trehalose derivatives and process for producing the same |
| JP5114627B2 (en) | 2006-03-27 | 2013-01-09 | 株式会社糖鎖工学研究所 | Trehalose compound and medicament containing the compound |
| CN100571707C (en) | 2006-07-24 | 2009-12-23 | 凌沛学 | The articular cavity inner injecting and administering preparations that contains trehalose |
| JP5258582B2 (en) | 2007-01-31 | 2013-08-07 | 株式会社糖鎖工学研究所 | Trehalose compound, method for producing the same, and immunostimulant containing the compound |
| EP2198869B1 (en) * | 2007-02-23 | 2015-09-16 | Next 21 K.K. | Trehalose for the treatment or prevention of vasospasm |
| WO2008133884A2 (en) | 2007-04-23 | 2008-11-06 | Combinatorx, Incorporated | Methods and compositions for the treatment of neurodegenerative disorders |
| CA2703946A1 (en) * | 2007-10-31 | 2009-05-07 | Diffusion Pharmaceuticals Llc | A new class of therapeutics that enhance small molecule diffusion |
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| US20110142799A1 (en) | 2008-06-23 | 2011-06-16 | President And Fellows Of Harvard College | Modulation of neurodegenerative disease by modulating xbp-1 activity |
| KR101021078B1 (en) | 2008-07-22 | 2011-03-14 | 포항공과대학교 산학협력단 | Inositol or trehalos derivatives and a pharmaceutical composition for treating neurodegenerative diseases containing same |
| WO2010050178A1 (en) | 2008-10-31 | 2010-05-06 | 大塚化学株式会社 | Trehalose compound, method for producing same, and pharmaceutical product containing the compound |
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| US9186356B2 (en) | 2011-01-08 | 2015-11-17 | Academia Sinica | Methods for treating frontotemporal lobar degeneration with ubiquitinated inclusions (FTLD-U) |
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| US9084720B2 (en) | 2013-05-07 | 2015-07-21 | BioBlast Pharma Ltd. | Compositions and methods for treating oculopharyngeal muscular dystrophy |
| KR20160009617A (en) | 2013-05-07 | 2016-01-26 | 바이오 블라스트 파마 리미티드 | Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose |
| JP6130224B2 (en) | 2013-05-27 | 2017-05-17 | 公益財団法人微生物化学研究会 | Novel compound lenteztrehalose, method for producing the same, use thereof, and novel microorganism |
| TWI507197B (en) | 2013-07-17 | 2015-11-11 | Univ Nat Taiwan Normal | Use of pharmaceutical composition for manufacturing drug of abnormal polyglutamine-mediated disease |
| US20160303150A1 (en) | 2015-04-16 | 2016-10-20 | BioBlast Pharma Ltd. | Deuterated trehalose formulations and uses thereof |
-
2014
- 2014-05-07 KR KR1020157034700A patent/KR20160009617A/en not_active Application Discontinuation
- 2014-05-07 AU AU2014264228A patent/AU2014264228A1/en not_active Abandoned
- 2014-05-07 CA CA2911399A patent/CA2911399A1/en active Pending
- 2014-05-07 WO PCT/IL2014/050411 patent/WO2014181333A2/en active Application Filing
- 2014-05-07 EP EP14733380.1A patent/EP2994145B1/en active Active
- 2014-05-07 PE PE2015002367A patent/PE20160012A1/en not_active Application Discontinuation
- 2014-05-07 EP EP22216238.0A patent/EP4218769A3/en active Pending
- 2014-05-07 MD MDA20150120A patent/MD20150120A2/en not_active Application Discontinuation
- 2014-05-07 US US14/889,727 patent/US10493023B2/en active Active
- 2014-05-07 JP JP2016512480A patent/JP6837835B2/en active Active
- 2014-05-07 SG SG11201509030TA patent/SG11201509030TA/en unknown
- 2014-05-07 EA EA201501054A patent/EA201501054A1/en unknown
- 2014-05-07 MX MX2015015355A patent/MX2015015355A/en unknown
-
2015
- 2015-09-21 IL IL241757A patent/IL241757B/en active IP Right Grant
- 2015-12-04 CR CR20150637A patent/CR20150637A/en unknown
-
2016
- 2016-05-10 HK HK16105328.4A patent/HK1217300A1/en unknown
-
2019
- 2019-04-11 JP JP2019075517A patent/JP2019142907A/en active Pending
- 2019-06-26 AU AU2019204513A patent/AU2019204513B2/en active Active
- 2019-07-02 US US16/460,046 patent/US10869831B2/en active Active
-
2020
- 2020-11-26 AU AU2020277197A patent/AU2020277197A1/en not_active Abandoned
-
2021
- 2021-06-08 JP JP2021095562A patent/JP2021152032A/en active Pending
- 2021-06-23 US US17/355,607 patent/US20220117883A1/en not_active Abandoned
-
2023
- 2023-01-11 JP JP2023002536A patent/JP2023040211A/en active Pending
- 2023-01-20 AU AU2023200303A patent/AU2023200303A1/en active Pending
- 2023-04-05 US US18/131,161 patent/US20240009113A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HK1217300A1 (en) | 2017-01-06 |
| JP2021152032A (en) | 2021-09-30 |
| MD20150120A2 (en) | 2016-03-31 |
| JP6837835B2 (en) | 2021-03-03 |
| US10869831B2 (en) | 2020-12-22 |
| WO2014181333A3 (en) | 2015-01-08 |
| US20220117883A1 (en) | 2022-04-21 |
| AU2019204513A1 (en) | 2019-07-18 |
| PE20160012A1 (en) | 2016-02-14 |
| US20190374463A1 (en) | 2019-12-12 |
| JP2016518403A (en) | 2016-06-23 |
| JP2023040211A (en) | 2023-03-22 |
| EP4218769A2 (en) | 2023-08-02 |
| IL241757B (en) | 2020-05-31 |
| AU2014264228A1 (en) | 2015-11-12 |
| AU2020277197A1 (en) | 2020-12-24 |
| EP4218769A3 (en) | 2023-10-18 |
| JP2019142907A (en) | 2019-08-29 |
| EA201501054A1 (en) | 2016-04-29 |
| AU2023200303A1 (en) | 2023-02-23 |
| CA2911399A1 (en) | 2014-11-13 |
| EP2994145A2 (en) | 2016-03-16 |
| EP2994145B1 (en) | 2023-01-04 |
| US10493023B2 (en) | 2019-12-03 |
| KR20160009617A (en) | 2016-01-26 |
| AU2019204513B2 (en) | 2020-09-10 |
| MX2015015355A (en) | 2016-07-18 |
| US20240009113A1 (en) | 2024-01-11 |
| WO2014181333A2 (en) | 2014-11-13 |
| US20160120798A1 (en) | 2016-05-05 |
| CR20150637A (en) | 2016-04-05 |
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