JP2016512194A5 - - Google Patents

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Publication number
JP2016512194A5
JP2016512194A5 JP2015561540A JP2015561540A JP2016512194A5 JP 2016512194 A5 JP2016512194 A5 JP 2016512194A5 JP 2015561540 A JP2015561540 A JP 2015561540A JP 2015561540 A JP2015561540 A JP 2015561540A JP 2016512194 A5 JP2016512194 A5 JP 2016512194A5
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JP
Japan
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amino
bromophenyl
optionally substituted
carbamoyl
alkyl
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JP2015561540A
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English (en)
Japanese (ja)
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JP2016512194A (ja
JP6196328B2 (ja
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Priority claimed from PCT/US2014/020273 external-priority patent/WO2014138046A1/en
Publication of JP2016512194A publication Critical patent/JP2016512194A/ja
Publication of JP2016512194A5 publication Critical patent/JP2016512194A5/ja
Application granted granted Critical
Publication of JP6196328B2 publication Critical patent/JP6196328B2/ja
Expired - Fee Related legal-status Critical Current
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JP2015561540A 2013-03-06 2014-03-04 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用 Expired - Fee Related JP6196328B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361773778P 2013-03-06 2013-03-06
US61/773,778 2013-03-06
PCT/US2014/020273 WO2014138046A1 (en) 2013-03-06 2014-03-04 Use of agonists of formyl peptide receptor 2 for treating dermatological diseases

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2017157336A Division JP6496787B2 (ja) 2013-03-06 2017-08-17 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用
JP2017157337A Division JP6496788B2 (ja) 2013-03-06 2017-08-17 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用

Publications (3)

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JP2016512194A JP2016512194A (ja) 2016-04-25
JP2016512194A5 true JP2016512194A5 (cg-RX-API-DMAC7.html) 2017-04-13
JP6196328B2 JP6196328B2 (ja) 2017-09-13

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ID=50389505

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2015561540A Expired - Fee Related JP6196328B2 (ja) 2013-03-06 2014-03-04 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用
JP2017157337A Expired - Fee Related JP6496788B2 (ja) 2013-03-06 2017-08-17 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用
JP2017157336A Expired - Fee Related JP6496787B2 (ja) 2013-03-06 2017-08-17 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用
JP2019043933A Expired - Fee Related JP6672499B2 (ja) 2013-03-06 2019-03-11 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2017157337A Expired - Fee Related JP6496788B2 (ja) 2013-03-06 2017-08-17 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用
JP2017157336A Expired - Fee Related JP6496787B2 (ja) 2013-03-06 2017-08-17 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用
JP2019043933A Expired - Fee Related JP6672499B2 (ja) 2013-03-06 2019-03-11 皮膚疾患を治療するためのホルミルペプチド受容体2アゴニストの使用

Country Status (13)

Country Link
US (5) US20140256685A1 (cg-RX-API-DMAC7.html)
EP (1) EP2964214A1 (cg-RX-API-DMAC7.html)
JP (4) JP6196328B2 (cg-RX-API-DMAC7.html)
KR (2) KR20210024691A (cg-RX-API-DMAC7.html)
CN (2) CN107714683A (cg-RX-API-DMAC7.html)
AR (1) AR095035A1 (cg-RX-API-DMAC7.html)
AU (3) AU2014226001B2 (cg-RX-API-DMAC7.html)
BR (2) BR112015021392B1 (cg-RX-API-DMAC7.html)
CA (3) CA3114347A1 (cg-RX-API-DMAC7.html)
HK (2) HK1219661A1 (cg-RX-API-DMAC7.html)
RU (1) RU2696487C2 (cg-RX-API-DMAC7.html)
TW (1) TW201446241A (cg-RX-API-DMAC7.html)
WO (1) WO2014138046A1 (cg-RX-API-DMAC7.html)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106518742B (zh) 2011-10-26 2020-01-21 阿勒根公司 作为甲酰肽受体样-1(fprl-1)受体调节剂的n-脲取代的氨基酸的酰胺衍生物
SG11201406629VA (en) * 2012-04-16 2014-11-27 Allergan Inc (2-ureidoacetamido)alkyl derivatives as formyl peptide receptor 2 modulators
CA2871334A1 (en) 2012-05-16 2013-11-21 Actelion Pharmaceuticals Ltd 1-(p-tolyl)cyclopropyl substituted bridged spiro[2.4]heptane derivatives as alx receptor agonists
MA37618B1 (fr) 2012-05-16 2017-08-31 Actelion Pharmaceuticals Ltd Dérivés pontés fluorés de spiro[2.4]heptane en tant qu'agonistes de récepteur alx
CN103665043B (zh) 2012-08-30 2017-11-10 江苏豪森药业集团有限公司 一种替诺福韦前药及其在医药上的应用
BR112015021392B1 (pt) * 2013-03-06 2021-11-16 Allergan, Inc Uso de agonistas do receptor de peptídeo formil 2 para tratar doenças dermatológicas
AR096686A1 (es) 2013-06-25 2016-01-27 Actelion Pharmaceuticals Ltd Derivados de espiro[2.4]heptano puenteados sustituidos con difluoroetil-oxazol como agonistas del receptor de alx
WO2015009545A1 (en) * 2013-07-16 2015-01-22 Allergan, Inc. Derivatives of n-urea substituted amino acids as formyl peptide receptor modulators
WO2015007830A1 (en) 2013-07-18 2015-01-22 Actelion Pharmaceuticals Ltd Piperazine substituted bridged spiro[2.4]heptane derivatives as alx receptor agonists
AR097279A1 (es) 2013-08-09 2016-03-02 Actelion Pharmaceuticals Ltd Derivados de benzimidazolil-metil urea como agonistas del receptor de alx
WO2015116566A1 (en) * 2014-01-29 2015-08-06 Allergan, Inc. 2,5-dioxoimidazolidin-1-yl-3-urea derivatives as formyl peptide modulators
US9663457B2 (en) 2014-04-09 2017-05-30 Allergan, Inc. Carbamoyl hydrazine derivatives as formyl peptide modulators
CA2948876A1 (en) 2014-05-21 2015-11-26 Allergan, Inc. Imidazole derivatives as formyl peptide receptor modulators
EP3414227B1 (en) * 2015-12-10 2021-11-24 Bristol-Myers Squibb Company Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists
CN109715602A (zh) * 2016-03-28 2019-05-03 阿勒根公司 苯基脲衍生物作为n-甲酰肽受体调节剂
EP3442950A1 (en) * 2016-04-12 2019-02-20 Allergan, Inc. Phenyl urea derivatives as n-formyl peptide receptor modulators
WO2018066646A1 (ja) * 2016-10-06 2018-04-12 第一三共株式会社 尿素誘導体
GB2561540A (en) * 2017-03-13 2018-10-24 Nodthera Ltd Chemical compounds
ES2799098B2 (es) * 2019-06-10 2021-12-10 Univ Madrid Carlos Iii Aptameros agonistas del receptor fpr2 y usos de los mismos

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4521210A (en) 1982-12-27 1985-06-04 Wong Vernon G Eye implant for relieving glaucoma, and device and method for use therewith
JPS63232846A (ja) 1987-03-20 1988-09-28 Haruo Ogura 新規な固定相担体
AU6909300A (en) * 1999-08-20 2001-03-19 Merck & Co., Inc. Substituted ureas as cell adhesion inhibitors
DE10005275A1 (de) * 2000-02-07 2001-08-09 Bayer Ag Neuartige Glycokonjugate
EP1162194A1 (en) 2000-06-06 2001-12-12 Aventis Pharma Deutschland GmbH Factor VIIa inhibitory (thio)urea derivatives, their preparation and their use
DE10063008A1 (de) 2000-12-16 2002-06-20 Merck Patent Gmbh Carbonsäureamidderivate
CN100497302C (zh) * 2002-09-05 2009-06-10 神经研究公司 二芳基脲衍生物和它们作为氯通道阻滞剂的用途
US7576206B2 (en) 2003-08-14 2009-08-18 Cephalon, Inc. Proteasome inhibitors and methods of using the same
EP1695961A4 (en) 2003-12-17 2007-10-24 Takeda Pharmaceutical UREA DERIVATIVE, METHOD FOR THE PRODUCTION AND THEIR USE
WO2006065755A2 (en) 2004-12-13 2006-06-22 Glaxo Group Limited Quaternary ammonium salts of fused hetearomatic amines as novel muscarinic acetylcholine receptor antagonists
WO2007076055A2 (en) * 2005-12-22 2007-07-05 Entremed, Inc. Compositions and methods comprising proteinase activated receptor antagonists
KR20090121832A (ko) * 2008-05-23 2009-11-26 인제대학교 산학협력단 2-(2-히드록시벤조일)히드라진카르복시아미드 유도체 또는이의 약학적으로 허용가능한 염, 이의 제조방법, 및 이를유효 성분으로 함유하는 선택적 면역 억제용 약학적 조성물
PT2362866E (pt) * 2008-11-11 2015-10-26 Signum Biosciences Inc Compostos de isoprenila e métodos dos mesmos
KR20100101055A (ko) * 2009-03-07 2010-09-16 주식회사 메디젠텍 세포핵에서 세포질로의 gsk3의 이동을 억제하는 화합물을 함유하는 세포핵에서 세포질로의 gsk3 이동 관련 질환의 치료 또는 예방용 약학적 조성물
WO2011073918A2 (en) * 2009-12-16 2011-06-23 Actelion Pharmaceuticals Ltd Peptides as modulators of fprl1 and/or fprl2
EP2585054A1 (en) * 2010-06-24 2013-05-01 Allergan, Inc. Derivatives of cycloalkyl- and cycloalkenyl-1,2-dicarboxylic acid compounds having formyl peptide receptor like-1 (fprl-1) agonist or antagonist activity
WO2012074785A1 (en) * 2010-12-03 2012-06-07 Allergan, Inc. Pharmaceutical compositions comprising 3,4- dihydroisoquinolin-2(1 h)-yl-3-phenylurea derivatives having formyl peptide receptor like-1 (fprl-1) agonist or antagonist activity
AU2012214265A1 (en) 2011-02-11 2013-09-05 Allergan, Inc. Novel 1-(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)urea derivatives as N-formyl peptide receptor like-1 (FPRL-1) receptor modulators
US8653299B2 (en) 2011-03-17 2014-02-18 Allergan, Inc. Dihydronaphthalene and naphthalene derivatives as N-formyl peptide receptor like-1 (FPRL-1) receptor modulators
CA2839735A1 (en) 2011-06-17 2012-12-20 Yong-xin LI D-serine for the treatment of visual system disorders
EP2731931A1 (en) 2011-07-11 2014-05-21 Allergan, Inc. Polycyclic pyrrolidine-2,5-dione derivatives as -formyl peptide receptor like-1 (fprl-1) receptor modulators
CN106518742B (zh) * 2011-10-26 2020-01-21 阿勒根公司 作为甲酰肽受体样-1(fprl-1)受体调节剂的n-脲取代的氨基酸的酰胺衍生物
US8541577B2 (en) * 2011-11-10 2013-09-24 Allergan, Inc. Aryl urea derivatives as N-formyl peptide receptors like-1 (FPRL-1) receptor modulators
US8492556B2 (en) * 2011-11-10 2013-07-23 Allergan, Inc. 2,5-Dioxoimidazolidin-1-yl-3-phenylurea derivatives as formyl peptide receptor like-1 (FPRL-1) receptor modulators
CA2864893A1 (en) 2012-02-16 2013-08-22 Allergan, Inc. Imidazolidine-2,4-dione derivatives as n-formyl peptide receptor 2 modulators
SG11201406629VA (en) * 2012-04-16 2014-11-27 Allergan Inc (2-ureidoacetamido)alkyl derivatives as formyl peptide receptor 2 modulators
BR122017004254B1 (pt) * 2013-03-06 2021-04-13 Allergan, Inc. Uso de agonistas de receptor de formil peptídeo 2 para tratar doenças inflamatórias oculares
BR112015021392B1 (pt) * 2013-03-06 2021-11-16 Allergan, Inc Uso de agonistas do receptor de peptídeo formil 2 para tratar doenças dermatológicas
WO2015009545A1 (en) * 2013-07-16 2015-01-22 Allergan, Inc. Derivatives of n-urea substituted amino acids as formyl peptide receptor modulators
WO2015042071A1 (en) 2013-09-19 2015-03-26 Allergan, Inc. Diphenyl urea derivatives as formyl peptide receptor modulators
RU2703725C1 (ru) 2013-11-21 2019-10-22 Аллерган, Инк. Производные фенилкарбамата в качестве модуляторов формилпептидного рецептора
CA2948876A1 (en) * 2014-05-21 2015-11-26 Allergan, Inc. Imidazole derivatives as formyl peptide receptor modulators

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